Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 33, 2003 - Issue 11
166
Views
71
CrossRef citations to date
0
Altmetric
Research Article

Bioavailability and half-life of decabromodiphenyl ether (BDE-209) in rat

, &
Pages 1149-1158 | Received 03 Apr 2003, Published online: 22 Sep 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Gabriel A. Knudsen, J. Michael Sanders, Michael F. Hughes, Ethan P. Hull & Linda S. Birnbaum. (2017) The biological fate of decabromodiphenyl ethane following oral, dermal or intravenous administration. Xenobiotica 47:10, pages 894-902.
Read now
Pamela D Noyes & Heather M Stapleton. (2014) PBDE flame retardants. Endocrine Disruptors 2:1.
Read now
Qian Luo, Jin-Miao Zha, Zijian Wang, Ming Hung Wong & Zongwei Cai. (2013) Bioaccumulation and debromination of BDE-209 in Japanese medaka (Oryzias Latipes) when continuously exposed to environmental relevant concentrations. Journal of Environmental Science and Health, Part A 48:11, pages 1349-1355.
Read now
Marcia L. Hardy, Marek Banasik & Todd Stedeford. (2009) Toxicology and human health assessment of decabromodiphenyl ether. Critical Reviews in Toxicology 39:sup3, pages 1-44.
Read now

Articles from other publishers (67)

Dieter Schrenk, Margherita Bignami, Laurent Bodin, James Kevin Chipman, Jesús del Mazo, Bettina Grasl‐Kraupp, Christer Hogstrand, Laurentius (Ron) Hoogenboom, Jean‐Charles Leblanc, Carlo Stefano Nebbia, Elsa Nielsen, Evangelia Ntzani, Annette Petersen, Salomon Sand, Tanja Schwerdtle, Heather Wallace, Diane Benford, Peter Fürst, Andy Hart, Martin Rose, Henri Schroeder, Martine Vrijheid, Sofia Ioannidou, Marina Nikolič, Luisa Ramos Bordajandi & Christiane Vleminckx. (2024) Update of the risk assessment of polybrominated diphenyl ethers (PBDEs) in food. EFSA Journal 22:1.
Crossref
Meiqing Lin, Shengtao Ma, Jian Tang, Yingxin Yu, Guiying Li, Ruifang Fan, Guoxia Zhang, Bixian Mai & Taicheng An. (2023) Polybrominated diphenyl ethers and bromophenols in paired serum, hair, and urine samples of e-waste dismantlers: Insights into hair as an indicator of endogenous exposure. Science of The Total Environment 871, pages 161980.
Crossref
Per Eriksson, Niclas Johansson, Henrik Viberg, Sonja Buratovic & Anders Fredriksson. (2023) Perfluorinated chemicals (PFOA) can, by interacting with highly brominated diphenyl ethers (PBDE 209) during a defined period of neonatal brain development, exacerbate neurobehavioural defects. Neurotoxicology and Teratology 96, pages 107150.
Crossref
Yu Wei, Wenfeng Geng, Taifa Zhang, Huan He & Jinxia Zhai. (2023) N-acetylcysteine rescues meiotic arrest during spermatogenesis in mice exposed to BDE-209. Environmental Science and Pollution Research 30:17, pages 50952-50968.
Crossref
Yi Yang, Xing Zhu, Qinxiong Rao, Zehui Liu, Junhua Yang & Zhihui Zhao. (2022) Toxicokinetics and edible tissues-specific bioaccumulation of decabrominated diphenyl ethers (BDE-209) after exposure to the broilers. Ecotoxicology and Environmental Safety 248, pages 114324.
Crossref
Zhichun Zhang, Man Hu, Dongliang Xuan, Linying Wu, Yanfei Zhang, Gengsheng He & Ying Zhou. (2022) Physiologically based pharmacokinetic (PBPK) modeling of BDE-209 following oral exposure in Chinese population. Food and Chemical Toxicology 169, pages 113416.
Crossref
Shengtao Ma, Guofa Ren, Kewen Zheng, Juntao Cui, Pei Li, Xiaomei Huang, Meiqing Lin, Ranran Liu, Jing Yuan, Wenjun Yin, Ping’an Peng, Guoying Sheng & Zhiqiang Yu. (2022) New Insights into Human Biotransformation of BDE-209: Unique Occurrence of Metabolites of Ortho-Substituted Hydroxylated Higher Brominated Diphenyl Ethers in the Serum of e-Waste Dismantlers. Environmental Science & Technology 56:14, pages 10239-10248.
Crossref
Guomao Zheng, Luma Melo, Rishika Chakraborty, James E. Klaunig & Amina Salamova. (2022) Biotransformation of 2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine (TTBP-TAZ) can contribute to high levels of 2,4,6-tribromophenol (2,4,6-TBP) in humans. Environment International 158, pages 106943.
Crossref
Svenja Neumann, Mikael Harju, Dorte Herzke, Tycho Anker-Nilssen, Signe Christensen-Dalsgaard, Magdalene Langset & Geir Wing Gabrielsen. (2021) Ingested plastics in northern fulmars (Fulmarus glacialis): A pathway for polybrominated diphenyl ether (PBDE) exposure?. Science of The Total Environment 778, pages 146313.
Crossref
Ziye Zheng, Hans Peter H. Arp, Gregory Peters & Patrik L. Andersson. (2020) Combining In Silico Tools with Multicriteria Analysis for Alternatives Assessment of Hazardous Chemicals: Accounting for the Transformation Products of decaBDE and Its Alternatives . Environmental Science & Technology 55:2, pages 1088-1098.
Crossref
Huiying Guo, Xiaobo Zheng, Shuling Ru, Xiaojun Luo & Bixian Mai. (2019) The leaching of additive-derived flame retardants (FRs) from plastics in avian digestive fluids: The significant risk of highly lipophilic FRs. Journal of Environmental Sciences 85, pages 200-207.
Crossref
Cynthia A. de Wit, Anna-Karin Johansson, Ulla Sellström & Peter Lindberg. (2019) Mass balance study of brominated flame retardants in female captive peregrine falcons. Environmental Science: Processes & Impacts 21:7, pages 1115-1131.
Crossref
Jing-Xin Wang, Lian-Jun Bao, Pei Luo, Lei Shi, Charles S. Wong & Eddy Y. Zeng. (2017) Intake, distribution, and metabolism of decabromodiphenyl ether and its main metabolites in chickens and implications for human dietary exposure. Environmental Pollution 231, pages 795-801.
Crossref
Sisi Liu, Guodong Zhao, Jun Li, Hongxia Zhao, Yafeng Wang, Jingwen Chen & Haidong Zhao. (2017) Association of polybrominated diphenylethers (PBDEs) and hydroxylated metabolites (OH-PBDEs) serum levels with thyroid function in thyroid cancer patients. Environmental Research 159, pages 1-8.
Crossref
Xiu-Bo Mi, Lian-Jun Bao, Chen-Chou Wu, Charles S. Wong & Eddy Y. Zeng. (2017) Absorption, tissue distribution, metabolism, and elimination of decabrominated diphenyl ether (BDE-209) in rats after multi-dose oral exposure. Chemosphere 186, pages 749-756.
Crossref
Xiu-Bo Mi, Yang Su, Lian-Jun Bao, Shu Tao & Eddy Y. Zeng. (2017) Significance of Cooking Oil to Bioaccessibility of Dichlorodiphenyltrichloroethanes (DDTs) and Polybrominated Diphenyl Ethers (PBDEs) in Raw and Cooked Fish: Implications for Human Health Risk. Journal of Agricultural and Food Chemistry 65:16, pages 3268-3275.
Crossref
Xiaopeng Chen, Yanping Lin, Katherine Dang & Birgit Puschner. (2017) Quantification of Polychlorinated Biphenyls and Polybrominated Diphenyl Ethers in Commercial Cows’ Milk from California by Gas Chromatography–Triple Quadruple Mass Spectrometry. PLOS ONE 12:1, pages e0170129.
Crossref
M. Cheikh Rouhou, A.D. Karelis, D.H. St-Pierre & L. Lamontagne. (2016) Adverse effects of weight loss: Are persistent organic pollutants a potential culprit?. Diabetes & Metabolism 42:4, pages 215-223.
Crossref
Marie-Line Gentes, Marc J. Mazerolle, Jean-François Giroux, Martin Patenaude-Monette & Jonathan Verreault. (2015) Tracking the sources of polybrominated diphenyl ethers in birds: Foraging in waste management facilities results in higher DecaBDE exposure in males. Environmental Research 138, pages 361-371.
Crossref
Miyoung Yoon, Alina Efremenko, Bas J. Blaauboer & Harvey J. Clewell. (2014) Evaluation of simple in vitro to in vivo extrapolation approaches for environmental compounds. Toxicology in Vitro 28:2, pages 164-170.
Crossref
Robert J. Letcher, Sarah C. Marteinson & Kim J. Fernie. (2014) Dietary exposure of American kestrels (Falco sparverius) to decabromodiphenyl ether (BDE-209) flame retardant: Uptake, distribution, debromination and cytochrome P450 enzyme induction. Environment International 63, pages 182-190.
Crossref
Mohamed Abou-Elwafa Abdallah & Stuart Harrad. (2014) Polybrominated diphenyl ethers in UK human milk: Implications for infant exposure and relationship to external exposure. Environment International 63, pages 130-136.
Crossref
Yanfeng Sun, Guofa Ren, Shengtao Ma, Kewen Zheng, Zhiqiang Yu, Minghong Wu, Guoying Sheng & Jiamo Fu. (2013) Synthesis of Br7–Br9 hydroxylated/methoxylated polybrominated diphenyl ethers (OH/MeO-PBDEs) and analyses on mass spectra and GC data of the MeO-PBDEs. Chemosphere 92:3, pages 286-292.
Crossref
Tetsuya Hirai, Yoshinori Fujimine, Shaw Watanabe & Takeshi Nakano. (2012) Distribution of polybrominated diphenyl ethers in Japanese autopsy tissue and body fluid samples. Environmental Science and Pollution Research 19:8, pages 3538-3546.
Crossref
T. Srikanth Reddy, N. Suryakiran, M. Narasimhulu, D. Ramesh, K. Chinni Mahesh, A. Sai Krishna, P. Kavitha, J. Venkateswara Rao & Y. Venkateswarlu. (2012) Semi-synthesis and bio-evaluation of polybrominated diphenyl ethers from the sponge Dysidea herbacea. Bioorganic & Medicinal Chemistry Letters 22:14, pages 4900-4906.
Crossref
Luis Heredia, Margarita Torrente, María T. Colomina & José L. Domingo. (2012) Behavioral effects of oral subacute exposure to BDE-209 in young adult mice: A preliminary study. Food and Chemical Toxicology 50:3-4, pages 707-712.
Crossref
Cynthia A. de Wit, Justina Awasum Björklund & Kaj Thuresson. (2012) Tri-decabrominated diphenyl ethers and hexabromocyclododecane in indoor air and dust from Stockholm microenvironments 2: Indoor sources and human exposure. Environment International 39:1, pages 141-147.
Crossref
Mohamed Abou-Elwafa Abdallah, Emma Tilston, Stuart Harrad & Chris Collins. (2012) In vitro assessment of the bioaccessibility of brominated flame retardants in indoor dust using a colon extended model of the human gastrointestinal tract. Journal of Environmental Monitoring 14:12, pages 3276.
Crossref
M. Vilaplana, G. Caminal, M. Sarrà, E. Barón, M. Gorga, B. Thienpont, D. Raldúa, E. Eljarrat & D. Barceló. 2013. Emerging Organic Contaminants in Sludges. Emerging Organic Contaminants in Sludges 241 270 .
Yongquan Lai, Minghua Lu, Xiang Gao, Hanzhi Wu & Zongwei Cai. (2011) New Evidence for Toxicity of Polybrominated Diphenyl Ethers: DNA Adduct Formation from Quinone Metabolites. Environmental Science & Technology 45:24, pages 10720-10727.
Crossref
Melissa A. McKinney, Rune Dietz, Christian Sonne, Sylvain De Guise, Karl Skirnisson, Karl Karlsson, Egill Steingrímsson & Robert J. Letcher. (2011) Comparative hepatic microsomal biotransformation of selected PBDEs, including decabromodiphenyl ether, and decabromodiphenyl ethane flame retardants in Arctic marine‐feeding mammals. Environmental Toxicology and Chemistry 30:7, pages 1506-1514.
Crossref
Shengyan Tian & Lingyan Zhu. (2011) Bioaccumulation kinetics of sediment-associated DE-83 in benthic invertebrates (Nereis succinea, polychaete). Chemosphere 84:1, pages 160-165.
Crossref
. (2011) Scientific Opinion on Polybrominated Diphenyl Ethers (PBDEs) in Food. EFSA Journal 9:5.
Crossref
Yongquan Lai, Xueguo Chen, Michael Hon-Wah Lam & Zongwei Cai. (2011) Analysis of hydroxylated polybrominated diphenyl ethers in rat plasma by using ultra performance liquid chromatography–tandem mass spectrometry. Journal of Chromatography B 879:15-16, pages 1086-1090.
Crossref
David Trudel, Martin Scheringer, Natalie von Goetz & Konrad Hungerbühler. (2011) Total Consumer Exposure to Polybrominated Diphenyl Ethers in North America and Europe. Environmental Science & Technology 45:6, pages 2391-2397.
Crossref
Yunmei Cai, Wenbing Zhang, Junjie Hu, Guoying Sheng, Dunjin Chen & Jiamo Fu. (2011) Characterization of maternal transfer of decabromodiphenyl ether (BDE-209) administered to pregnant Sprague–Dawley rats. Reproductive Toxicology 31:1, pages 106-110.
Crossref
Lucio G. Costa & Gennaro Giordano. (2011) Is decabromodiphenyl ether (BDE-209) a developmental neurotoxicant?. NeuroToxicology 32:1, pages 9-24.
Crossref
Melissa A. McKinney, Ian Stirling, Nick J. Lunn, Elizabeth Peacock & Robert J. Letcher. (2010) The role of diet on long-term concentration and pattern trends of brominated and chlorinated contaminants in western Hudson Bay polar bears, 1991–2007. Science of The Total Environment 408:24, pages 6210-6222.
Crossref
ChengLian Feng, YiPing Xu, JinMiao Zha, Qian Luo, XiaoQuan Shan & ZiJian Wang. (2010) Toxicokinetics and the related metabolites in rainbow trout (Oncorhynchus mykiss) after exposure to decabromodiphenyl ether. Science China Chemistry 53:11, pages 2379-2386.
Crossref
John A. Biesemeier, Melissa J. Beck, Hanna Silberberg, Nicole R. Myers, John M. Ariano, Eric S. Bodle, Daniel W. Sved, Sylvia Jacobi, Donald G. Stump, Marcia Hardy & Todd Stedeford. (2010) Effects of Dose, Administration Route, and/or Vehicle on Decabromodiphenyl Ether Concentrations in Plasma of Maternal, Fetal, and Neonatal Rats and in Milk of Maternal Rats. Drug Metabolism and Disposition 38:10, pages 1648-1654.
Crossref
Dongli Wang & Qing X. Li. (2009) Application of mass spectrometry in the analysis of polybrominated diphenyl ethers. Mass Spectrometry Reviews 29:5, pages 737-775.
Crossref
Marie Frederiksen, Marianne Thomsen, Katrin Vorkamp & Lisbeth E. Knudsen. (2009) Patterns and concentration levels of polybrominated diphenyl ethers (PBDEs) in placental tissue of women in Denmark. Chemosphere 76:11, pages 1464-1469.
Crossref
Tairan Xing, Liang Chen, Yanan Tao, Ming Wang, Jutao Chen & Di-Yun Ruan. (2009) Effects of Decabrominated Diphenyl Ether (PBDE 209) Exposure at Different Developmental Periods on Synaptic Plasticity in the Dentate Gyrus of Adult Rats In Vivo. Toxicological Sciences 110:2, pages 401-410.
Crossref
Jiang-Ping Wu, Xiao-Jun Luo, Ying Zhang, She-Jun Chen, Bi-Xian Mai, Yun-Tao Guan & Zhong-Yi Yang. (2009) Residues of Polybrominated Diphenyl Ethers in Frogs ( Rana limnocharis ) from a Contaminated Site, South China: Tissue Distribution, Biomagnification, and Maternal Transfer . Environmental Science & Technology 43:14, pages 5212-5217.
Crossref
Katherine E. Potter, Bryan D. Watts, Mark J. La Guardia, Ellen P. Harvey & Robert C. Hale. (2009) Polybrominated diphenyl ether flame retardants in Chesapeake Bay region, USA, peregrine falcon ( Falco peregrinus ) eggs: Urban/rural trends . Environmental Toxicology and Chemistry 28:5, pages 973-981.
Crossref
Susan D. Shaw, Diane Brenner, Michelle L. Berger, Fu Fang, Chia-Swee Hong, Rudolf Addink & David Hilker. (2008) Bioaccumulation of polybrominated diphenyl ethers in harbor seals from the northwest Atlantic. Chemosphere 73:11, pages 1773-1780.
Crossref
N. Johansson, H. Viberg, A. Fredriksson & P. Eriksson. (2008) Neonatal exposure to deca-brominated diphenyl ether (PBDE 209) causes dose–response changes in spontaneous behaviour and cholinergic susceptibility in adult mice. NeuroToxicology 29:6, pages 911-919.
Crossref
Robert G. Arnold, Sondra Teske, Matt Tomanek, Jason Engstrom, Cary Leung, Jianmin Zhang, Qais Banihani, David Quanrud, Wendell P. Ela & A. Eduardo Sáez. (2008) Fate of Polybrominated Diphenyl Ethers during Wastewater Treatment/Polishing and Sludge Stabilization/Disposal. Annals of the New York Academy of Sciences 1140:1, pages 394-411.
Crossref
Espen Mariussen, Eiliv Steinnes, Knut Breivik, Torgeir Nygård, Martin Schlabach & John Atle Kålås. (2008) Spatial patterns of polybrominated diphenyl ethers (PBDEs) in mosses, herbivores and a carnivore from the Norwegian terrestrial biota. Science of The Total Environment 404:1, pages 162-170.
Crossref
Chris E. Talsness. (2008) Overview of toxicological aspects of polybrominated diphenyl ethers: A flame-retardant additive in several consumer products. Environmental Research 108:2, pages 158-167.
Crossref
Leo T.M. Van der Ven, Ton van de Kuil, Pim E.G. Leonards, Wout Slob, Rocío F. Cantón, Silke Germer, Theo J. Visser, Sabina Litens, Helen Håkansson, Dieter Schrenk, Martin van den Berg, Aldert H. Piersma, Josephus G. Vos & Antoon Opperhuizen. (2008) A 28-day oral dose toxicity study in Wistar rats enhanced to detect endocrine effects of decabromodiphenyl ether (decaBDE). Toxicology Letters 179:1, pages 6-14.
Crossref
Anne Riu, Jean-Pierre Cravedi, Laurent Debrauwer, Aurélie Garcia, Cécile Canlet, Isabelle Jouanin & Daniel Zalko. (2008) Disposition and metabolic profiling of [14C]-Decabromodiphenyl ether in pregnant Wistar rats. Environment International 34:3, pages 318-329.
Crossref
Ying Guo, Xiang‐Zhou Meng, Hong‐Lei Tang, Bi‐Xian Mai & Eddy Y. Zeng. (2009) Distribution of polybrominated diphenyl ethers in fish tissues from the Pearl River Delta, China: Levels, compositions, and potential sources. Environmental Toxicology and Chemistry 27:3, pages 576-582.
Crossref
Tatsuya Kunisue, Nozomi Takayanagi, Tomohiko Isobe, Shin Takahashi, Susumu Nakatsu, Toshio Tsubota, Keisuke Okumoto, Sumio Bushisue, Kazuyuki Shindo & Shinsuke Tanabe. (2007) Regional Trend and Tissue Distribution of Brominated Flame Retardants and Persistent Organochlorines in Raccoon Dogs (Nyctereutes procyonoides) from Japan. Environmental Science & Technology 42:3, pages 685-691.
Crossref
Tatsuya Kunisue, Nozomi Takayanagi, Tomohiko Isobe, Shin Takahashi, Masato Nose, Taketo Yamada, Hiroaki Komori, Norimasa Arita, Norifumi Ueda & Shinsuke Tanabe. (2007) Polybrominated diphenyl ethers and persistent organochlorines in Japanese human adipose tissues. Environment International 33:8, pages 1048-1056.
Crossref
E. Van den Steen, A. Covaci, V.L.B. Jaspers, T. Dauwe, S. Voorspoels, M. Eens & R. Pinxten. (2007) Accumulation, tissue-specific distribution and debromination of decabromodiphenyl ether (BDE 209) in European starlings (Sturnus vulgaris). Environmental Pollution 148:2, pages 648-653.
Crossref
Janice K. Huwe & David J. Smith. (2007) Accumulation, Whole-Body Depletion, and Debromination of Decabromodiphenyl Ether in Male Sprague−Dawley Rats Following Dietary Exposure. Environmental Science & Technology 41:7, pages 2371-2377.
Crossref
Rocío F. Cantón, J. Thomas Sanderson, Sandra Nijmeijer, Åke Bergman, Robert J. Letcher & Martin van den Berg. (2006) In vitro effects of brominated flame retardants and metabolites on CYP17 catalytic activity: A novel mechanism of action?. Toxicology and Applied Pharmacology 216:2, pages 274-281.
Crossref
Henrik Viberg, Niclas Johansson, Anders Fredriksson, Johan Eriksson, Göran Marsh & Per Eriksson. (2006) Neonatal Exposure to Higher Brominated Diphenyl Ethers, Hepta-, Octa-, or Nonabromodiphenyl Ether, Impairs Spontaneous Behavior and Learning and Memory Functions of Adult Mice. Toxicological Sciences 92:1, pages 211-218.
Crossref
Maria Athanasiadou, Göran Marsh, Ioannis Athanassiadis, Lillemor Asplund & Åke Bergman. (2006) Gas chromatography and mass spectrometry of methoxylated polybrominated diphenyl ethers (MeO‐PBDEs). Journal of Mass Spectrometry 41:6, pages 790-801.
Crossref
Kaj Thuresson, Peter Höglund, Lars Hagmar, Andreas Sjödin, Åke Bergman & Kristina Jakobsson. (2006) Apparent Half-Lives of Hepta- to Decabrominated Diphenyl Ethers in Human Serum as Determined in Occupationally Exposed Workers. Environmental Health Perspectives 114:2, pages 176-181.
Crossref
Per Ola Darnerud & Sofia Risberg. (2006) Tissue localisation of tetra- and pentabromodiphenyl ether congeners (BDE-47, -85 and -99) in perinatal and adult C57BL mice. Chemosphere 62:3, pages 485-493.
Crossref
Ulla Sellström, Cynthia A. de Wit, Nadja Lundgren & Mats Tysklind. (2005) Effect of Sewage-Sludge Application on Concentrations of Higher-Brominated Diphenyl Ethers in Soils and Earthworms. Environmental Science & Technology 39:23, pages 9064-9070.
Crossref
Tina Malmberg, Maria Athanasiadou, Göran Marsh, Ingvar Brandt & Åke Bergman. (2005) Identification of Hydroxylated Polybrominated Diphenyl Ether Metabolites in Blood Plasma from Polybrominated Diphenyl Ether Exposed Rats. Environmental Science & Technology 39:14, pages 5342-5348.
Crossref
Lingyan Y. Zhu & Ronald A. Hites. (2005) Brominated Flame Retardants in Sediment Cores from Lakes Michigan and Erie. Environmental Science & Technology 39:10, pages 3488-3494.
Crossref
Kaj Thuresson, Åke Bergman & Kristina Jakobsson. (2005) Occupational Exposure to Commercial Decabromodiphenyl Ether in Workers Manufacturing or Handling Flame-Retarded Rubber. Environmental Science & Technology 39:7, pages 1980-1986.
Crossref
Gareth O. Thomas, Simon E.W. Moss, Lillemor Asplund & Ailsa J. Hall. (2005) Absorption of decabromodiphenyl ether and other organohalogen chemicals by grey seals (Halichoerus grypus). Environmental Pollution 133:3, pages 581-586.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.