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Xenobiotica
the fate of foreign compounds in biological systems
Volume 34, 2004 - Issue 6
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Research Article

Prediction of clinical pharmacokinetic parameters of linezolid using animal data by allometric scaling: applicability for the development of novel oxazolidinones

R. K. Bhamidipati Drug Metabolism and Pharmacokinetics, Discovery Research, Dr. Reddy's Laboratories Ltd, Miyapur, Hyderabad - 500 049, IndiaCorrespondence[email protected]
,
P. V. Dravid Drug Metabolism and Pharmacokinetics, Discovery Research, Dr. Reddy's Laboratories Ltd, Miyapur, Hyderabad - 500 049, India
,
R. Mullangi Drug Metabolism and Pharmacokinetics, Discovery Research, Dr. Reddy's Laboratories Ltd, Miyapur, Hyderabad - 500 049, India
&
N. R. Srinivas Drug Metabolism and Pharmacokinetics, Discovery Research, Dr. Reddy's Laboratories Ltd, Miyapur, Hyderabad - 500 049, India
Pages 571-579 | Received 04 Dec 2003, Published online: 22 Sep 2008

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Nuggehally R. Srinivas. (2016) Interspecies scaling of excretory amounts using allometry – retrospective analysis with rifapentine, aztreonam, carumonam, pefloxacin, miloxacin, trovafloxacin, doripenem, imipenem, cefozopran, ceftazidime, linezolid for urinary excretion and rifapentine, cabotegravir, and dolutegravir for fecal excretion. Xenobiotica 46:9, pages 784-792.
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Jeng-Pyng Shaw & Sarah Jaw-Tsai. (2011) An interspecies extrapolation of the pharmacokinetics of telavancin, a rapidly bactericidal, concentration-dependent antibiotic. Xenobiotica 41:1, pages 82-89.
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P. Ahlawat & N. R. Srinivas. (2008) Interspecies scaling of a camptothecin analogue: Human predictions for intravenous topotecan using animal data. Xenobiotica 38:11, pages 1377-1385.
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Articles from other publishers (8)

Ravi Kanth Bhamidipati, Sandip Gurav, Anitha Police, Zainuddin Mohd, Sriram Rajagopal & Ramesh Mullangi. (2017) The human pharmacokinetics of odanacatib, a novel cathepsin K inhibitor, predicted by interspecies scaling: a retrospective analysis. International Journal of Pharmacokinetics 2:1, pages 47-55.
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Voon Ong, Shawn Flanagan, Edward Fang, Howard J. Dreskin, Jeffrey B. Locke, Kenneth Bartizal & Philippe Prokocimer. (2014) Absorption, Distribution, Metabolism, and Excretion of the Novel Antibacterial Prodrug Tedizolid Phosphate. Drug Metabolism and Disposition 42:8, pages 1275-1284.
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Mark G. Papich. (2013) Antibiotic Treatment of Resistant Infections in Small Animals. Veterinary Clinics of North America: Small Animal Practice 43:5, pages 1091-1107.
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Nuggehally R. Srinivas, Preeti Ahlawat & Jafar Bhasha Shaik. (2013) Allometric Modeling of Ciclesonide, a Nonhalogenated Glucocorticoid, and Its Active Metabolite, Desisobutyrylciclesonide, Using Animal-Derived Pharmacokinetic Parameters. American Journal of Therapeutics 20:3, pages 261-266.
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Mark G. Papich. (2012) Selection of antibiotics for meticillin-resistant Staphylococcus pseudintermedius: time to revisit some old drugs?. Veterinary Dermatology 23:4, pages 352-e64.
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Ravindranath Reddy Gilibili, Ramesh Mullangi & Nuggehally R. Srinivas. (2011) Intravenous prediction of human pharmacokinetic parameters for ketorolac, a non-steroidal anti-inflammatory agent, using allometry approach. European Journal of Drug Metabolism and Pharmacokinetics 36:2, pages 87-93.
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Ramesh Mullangi, Preeti Ahlawat, Ravi K. Trivedi & Nuggehally R. Srinivas. (2009) Use of bile correction factors for allometric prediction of human pharmacokinetic parameters of torcetrapib, a facile cholesteryl ester transfer protein inhibitor. European Journal of Drug Metabolism and Pharmacokinetics 34:1, pages 57-63.
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Alexander Kuhl, Niels Svenstrup, Christoph Ladel, Michael Otteneder, Annegret Binas, Guido Schiffer, Michael Brands, Thomas Lampe, Karl Ziegelbauer, Helga Rübsamen-Waigmann, Dieter Haebich & Kerstin Ehlert. (2005) Biological Characterization of Novel Inhibitors of the Gram-Positive DNA Polymerase IIIC Enzyme. Antimicrobial Agents and Chemotherapy 49:3, pages 987-995.
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