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Xenobiotica
the fate of foreign compounds in biological systems
Volume 34, 2004 - Issue 6
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Research Article

Metabolism of the antineoplastic and immunosuppressive drug 2-CdA (Leustatin®) in animals and humans

W. N. Wu Division of Preclinical Drug Evaluation, Johnson & Johnson Pharmaceutical Research & Development, L.L.C, Spring House, PA, USA
,
L. A. Mckown Division of Preclinical Drug Evaluation, Johnson & Johnson Pharmaceutical Research & Development, L.L.C, Spring House, PA, USA
,
M. D. Moyer Division of Preclinical Drug Evaluation, Johnson & Johnson Pharmaceutical Research & Development, L.L.C, Spring House, PA, USA
&
W. Cheung Division of Clinical Drug Development, Johnson & Johnson Pharmaceutical Research & Development, L.L.C, Raritan, NJ, USA
Pages 591-606 | Received 28 Jan 2004, Published online: 22 Sep 2008

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Holger Scheible, Marc Laisney, Elmar Wimmer, Ana Javornik & Hugues Dolgos. (2013) Comparison of the in vitro and in vivo metabolism of Cladribine (Leustatin, Movectro) in animals and human. Xenobiotica 43:12, pages 1084-1094.
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Articles from other publishers (3)

Stefan H.P. Kraus, Felix Luessi, Bettina Trinschek, Steffen Lerch, Mario Hubo, Laura Poisa-Beiro, Magdalena Paterka, Helmut Jonuleit, Frauke Zipp & Valérie Jolivel. (2014) Cladribine exerts an immunomodulatory effect on human and murine dendritic cells. International Immunopharmacology 18:2, pages 347-357.
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Xingxing Diao. 2014. Handbook of Metabolic Pathways of Xenobiotics. Handbook of Metabolic Pathways of Xenobiotics 1 3 .
Robert S. Jansen, Hilde Rosing, Cocky J. F. de Wolf & Jos H. Beijnen. (2007) Development and validation of an assay for the quantitative determination of cladribine nucleotides in MDCKII cells and culture medium using weak anion-exchange liquid chromatography coupled with tandem mass spectrometry. Rapid Communications in Mass Spectrometry 21:24, pages 4049-4059.
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