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Xenobiotica
the fate of foreign compounds in biological systems
Volume 35, 2005 - Issue 8
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Research Article

Chemometric analysis of biofluids following toxicant induced hepatotoxicity: A metabonomic approach to distinguish the effects of 1-naphthylisothiocyanate from its products

J. Azmi Section of Biological Chemistry, Division of Biomedical Sciences, Imperial College of Science Technology & Medicine, London, UK
,
J. L. Griffin Department of Biochemistry, University of Cambridge, Cambridge, UK
,
R. F. Shore CEH Monks Wood, Abbots Ripton, Huntingdon, UK
,
E. Holmes Section of Biological Chemistry, Division of Biomedical Sciences, Imperial College of Science Technology & Medicine, London, UK
&
J. K. Nicholson Section of Biological Chemistry, Division of Biomedical Sciences, Imperial College of Science Technology & Medicine, London, UK
Pages 839-852 | Published online: 22 Sep 2008

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Natalie J Serkova & Mark S Brown. (2012) Quantitative Analysis in Magnetic Resonance Spectroscopy: From Metabolic Profiling to In Vivo Biomarkers. Bioanalysis 4:3, pages 321-341.
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Laura K. Schnackenberg & Richard D. Beger. (2008) The Role of Metabolic Biomarkers in Drug Toxicity Studies. Toxicology Mechanisms and Methods 18:4, pages 301-311.
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Deirdre A. Mahle, Paul E. Anderson, Nicholas J. DelRaso, Michael L. Raymer, Andrew E. Neuforth & Nicholas V. Reo. (2010) A generalized model for metabolomic analyses: application to dose and time dependent toxicity. Metabolomics 7:2, pages 206-216.
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Chunfeng Lu, Yimei Wang, Zhiguo Sheng, Gang Liu, Ze Fu, Jing Zhao, Jun Zhao, Xianzhong Yan, Benzhan Zhu & Shuangqing Peng. (2010) NMR-based metabonomic analysis of the hepatotoxicity induced by combined exposure to PCBs and TCDD in rats. Toxicology and Applied Pharmacology 248:3, pages 178-184.
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Paul E. Anderson, Michael L. Raymer, Benjamin J. Kelly, Nicholas V. Reo, Nicholas J. DelRaso & T. E. Doom. (2009) Characterization of 1H NMR spectroscopic data and the generation of synthetic validation sets. Bioinformatics 25:22, pages 2992-3000.
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Oliver AH Jones, Mahon L Maguire & Julian L Griffin. (2008) Environmental pollution and diabetes: a neglected association. The Lancet 371:9609, pages 287-288.
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R Sabnis. 2007. Handbook of Acid-Base Indicators. Handbook of Acid-Base Indicators 243 281 .
Bin Wu. (2007) Metabonomic technique and prospect of its application in integrated traditional Chinese and Western medicine research. Journal of Chinese Integrative Medicine, pages 475-480.
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Willem G. E. J. Schoonen, Cathelijne P. A. M. Kloks, Jan-Peter H. T. M. Ploemen, Martin J. Smit, Pieter Zandberg, G. Jean Horbach, Jan-Remt Mellema, Carol Thijssen-vanZuylen, Albert C. Tas, Joop H. J. van Nesselrooij & Jack T. W. E. Vogels. (2007) Uniform Procedure of 1H NMR Analysis of Rat Urine and Toxicometabonomics Part II: Comparison of NMR Profiles for Classification of Hepatotoxicity. Toxicological Sciences 98:1, pages 286-297.
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Julian L. Griffin & Richard F. Shore. 2007. The Handbook of Metabonomics and Metabolomics. The Handbook of Metabonomics and Metabolomics 517 532 .
Ching Yu Lin, Mark R. Viant & Ronald S. Tjeerdema. (2006) Metabolomics: Methodologies and applications in the environmental sciences. Journal of Pesticide Science 31:3, pages 245-251.
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