References
- Anthony ML, Sweatman BC, Beddell CR, Lindon JC, Nicholson JK. Pattern recognition classification of the site of nephrotoxicity based on metabolic data derived from proton nuclear magnetic resonance spectra of urine. Molecular Pharmacology 1994; 46: 199–211
- Azmi JK, Griffin JL, Antti H, Shore RF, Johansson E, Nicholson JK, Holmes E. Metabolic trajectory characterisation of xenobiotic-induced hepatotoxic lesions using statistical batch processing of NMR data. Analyst 2002; 127: 271–276
- Bailie NM, Pearson JM, Lappin PB, Killam AL, Roth RA. Platelets and α-naphthylisothiocyanate-induced liver injury. Toxicology and Applied Pharmacology 1994; 129: 207–213
- Beckwith-Hall BM, Nicholson JK, Nicholls AW, Foxall PJD, Lindon JC, Connor SC, Abdi M, Connelly J, Holmes E. Nuclear magnetic resonance spectroscopic and principal components analysis investigations into biochemical effects of three model hepatotoxins. Chemical Research in Toxicology 1998; 11: 260–272
- Carpenter-Deyo L, Marchand DH, Jean PA, Roth RA, Reed DJ. Involvement of glutathione in 1-naphthylisothiocyanate (ANIT) metabolism and toxicity to isolated hepatocytes. Biochemistry and Pharmacology 1991; 42: 2171–2180
- Dahm LJ, Roth RA. Protection against α-naphthylisothiocyanate-induced liver injury by decreased hepatic non-protein sulfhydryl content. Biochemistry and Pharmacology 1991; 42: 1181–1188
- Elms J, Beckett PN, Griffin P, Curran AD. Mechanisms of isocyanate sensitization. An in vitro approach. Toxicology In Vitro 2001; 15: 631–634
- Ferreira FM, Oliveira PJ, Rolo AP, Santos MS, Moreno AJ, Da Cunha MF, Seica R, Palmeira CM. Cholestasis induced by chronic treatment with alpha-naphthylisothiocyanate (ANIT) affects rat renal mitochondrial bioenergetics. Archives in Toxicology 2003; 77: 194–200
- Goldfarb S, Singer EJ, Popper H. Experimental cholangitis due to alpha-naphthyl-isothiocyanate (ANIT). American Journal of Pathology 1962; 40: 685–697
- Holmes E, Nicholls AW, Lindon JC, Ramos S, Spraul M, Neidig P, Connor SC, Connelly J, Damment SJP, Haselden J, Nicholson JK. Development of a model for classification of toxin-induced lesions using 1H-NMR spectroscopy of urine combined with pattern recognition. NMR Biomedicine 1998; 11: 235–244
- Jean PA, Roth RA. Naphthylsiothiocyanate disposition in bile and its relationship to liver glutathione and toxicity. Biochemistry and Pharmacology 1995; 50: 1469–1474
- Kossor DC, Meunier PC, Dulik DM, Leonard TB, Goldstein RS. Bile duct obstruction is not a prerequisite for type I biliary epithelial cell hyperplasia. Toxicology and Applied Pharmacology 1998; 152: 327–338
- Li Y, Yousef IM, Plaa GL. 1-Naphthyl isocyanate and 1-naphthylamine as metabolites of 1-naphthylisothiocyanate. Liver 1995; 15: 271–275
- Nicholson JK, Connelly J, Lindon JC, Holmes E. Metabonomics: A platform for studying drug toxicity and gene function. Nature Reviews Drug Discovery 2002; 1: 153–161
- Nicholson JK, Wilson ID. High resolution nuclear magnetic resonance spectroscopy of biological samples as an aid to drug development. Progress in Drug Research 1987; 31: 427–479
- Nicholson JK, Wilson ID. High resolution proton magnetic resonance spectroscopy of biological fluids. Progress in NMR Spectroscopy 1989; 21: 449–501
- Rolo AP, Oliveira PJ, Moreno AJM, Palmeira CM. Bile acids affect liver mitochondrial bioenergetics: Possible relevance for cholestasis therapy. Toxicology Science 2000; 57: 177–185
- Tur-Kaspa R, Adler R, Popovtzer MM, Eliakim M. Polyuria in experimental intrahepatic cholangitis by alpha-naphthyl-isothiocyanate. European Journal of Clinical Investigation 1983; 13: 19–24
- Waters NJ, Holmes E, Williams A, Waterfield CJ, Farrant RD, Nicholson JK. NMR and pattern recognition studies on the time-related metabolic effects of α-naphthylisothiocyanate on liver, urine, and plasma in the rat: An integrative metabonomic approach. Chemical Research in Toxicology 2001; 14: 1401–1412