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Xenobiotica
the fate of foreign compounds in biological systems
Volume 36, 2006 - Issue 2-3
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Research Article

Urinary excretion of the main metabolites of methamphetamine, including p-hydroxymethamphetamine-sulfate and p-hydroxymethamphetamine-glucuronide, in humans and rats

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Pages 259-267 | Received 01 Dec 2005, Published online: 22 Sep 2008

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Read on this site (4)

Nasim Nourani, Arezou Taghvimi, Ahad Bavili-Tabrizi, Yousef Javadzadeh & Siavoush Dastmalchi. (2022) Microextraction Techniques for Sample Preparation of Amphetamines in Urine: A Comprehensive Review. Critical Reviews in Analytical Chemistry 0:0, pages 1-16.
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Adeline M. Nyamathi, Benissa E. Salem, David Farabee & Sheldon Zhang. (2017) Differential reporting of drug use among gay, bisexual and transgender stimulant-using homeless adults post intervention. Journal of Substance Use 22:2, pages 218-224.
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N. Shima, M. Katagi, H. Kamata, K. Zaitsu, T. Kamata, M. Nishikawa, A. Miki, H. Tsuchihashi, T. Sakuma & N. Nemoto. (2008) Urinary excretion of the main metabolites of 3,4-methylenedioxymethamphetamine (MDMA), including the sulfate and glucuronide of 4-hydroxy-3-methoxymethamphetamine (HMMA), in humans and rats. Xenobiotica 38:3, pages 314-324.
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H. T. Kamata, N. Shima, K. Zaitsu, T. Kamata, A. Miki, M. Nishikawa, M. Katagi & H. Tsuchihashi. (2006) Metabolism of the recently encountered designer drug, methylone, in humans and rats. Xenobiotica 36:8, pages 709-723.
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Articles from other publishers (25)

Kartikay Lal, Frazer Noble & Khalid Mahmood Arif. (2022) Methamphetamine detection using nanoparticle-based biosensors: A comprehensive review. Sensing and Bio-Sensing Research 38, pages 100538.
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Hidenao Kakehashi, Takahiro Doi, Misato Wada, Tooru Kamata, Noriaki Shima, Akari Miyake, Atsushi Nitta, Ryutaro Asai, Shihoko Fujii, Shuntaro Matsuta, Keiko Sasaki, Hiroe Kamata, Hiroshi Nishioka, Akihiro Miki, Hiroshi Hasegawa & Munehiro Katagi. (2021) Human and rat microsomal metabolites of N-tert-butoxycarbonylmethamphetamine and its urinary metabolites in rat. Forensic Toxicology 40:1, pages 75-87.
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Arezou Taghvimi, Ahad Bavili Tabrizi, Siavoush Dastmalchi & Yousef Javadzadeh. (2019) Metal organic framework based carbon porous as an efficient dispersive solid phase extraction adsorbent for analysis of methamphetamine from urine matrix. Journal of Chromatography B 1109, pages 149-154.
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Achim T. Caspar, Folker Westphal, Markus R. Meyer & Hans H. Maurer. (2017) LC-high resolution-MS/MS for identification of 69 metabolites of the new psychoactive substance 1-(4-ethylphenyl-)-N-[(2-methoxyphenyl)methyl] propane-2-amine (4-EA-NBOMe) in rat urine and human liver S9 incubates and comparison of its screening power with further MS techniques. Analytical and Bioanalytical Chemistry 410:3, pages 897-912.
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Lilian H.J. Richter, Veit Flockerzi, Hans H. Maurer & Markus R. Meyer. (2017) Pooled human liver preparations, HepaRG, or HepG2 cell lines for metabolism studies of new psychoactive substances? A study using MDMA, MDBD, butylone, MDPPP, MDPV, MDPB, 5-MAPB, and 5-API as examples. Journal of Pharmaceutical and Biomedical Analysis 143, pages 32-42.
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David J. Wagner, Jennifer E. Sager, Haichuan Duan, Nina Isoherranen & Joanne Wang. (2017) Interaction and Transport of Methamphetamine and its Primary Metabolites by Organic Cation and Multidrug and Toxin Extrusion Transporters. Drug Metabolism and Disposition 45:7, pages 770-778.
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Christian Görgens, Sven Guddat, Andreas Thomas, Philipp Wachsmuth, Anne-Katrin Orlovius, Gerd Sigmund, Mario Thevis & Wilhelm Schänzer. (2016) Simplifying and expanding analytical capabilities for various classes of doping agents by means of direct urine injection high performance liquid chromatography high resolution/high accuracy mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis 131, pages 482-496.
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Elli Tyrkkö, Mikael Andersson & Robert Kronstrand. (2016) The Toxicology of New Psychoactive Substances. Therapeutic Drug Monitoring 38:2, pages 190-216.
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Christian Görgens, Sven Guddat, Anne-Katrin Orlovius, Gerd Sigmund, Andreas Thomas, Mario Thevis & Wilhelm Schänzer. (2015) “Dilute-and-inject” multi-target screening assay for highly polar doping agents using hydrophilic interaction liquid chromatography high resolution/high accuracy mass spectrometry for sports drug testing. Analytical and Bioanalytical Chemistry 407:18, pages 5365-5379.
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Alistair K. Brown & Charles S. Wong. (2015) Current trends in environmental analysis of human metabolite conjugates of pharmaceuticals. Trends in Environmental Analytical Chemistry 5, pages 8-17.
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Dennis K. Miller, Clark E. Oelrichs, Grace Y. Sun & Agnes Simonyi. (2014) Subchronic apocynin treatment attenuates methamphetamine-induced dopamine release and hyperactivity in rats. Life Sciences 98:1, pages 6-11.
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Kenji Kuwayama, Kenji Tsujikawa, Hajime Miyaguchi, Tatsuyuki Kanamori, Yuko T. Iwata & Hiroyuki Inoue. (2011) Interaction of 3,4‐Methylenedioxymethamphetamine and Methamphetamine During Metabolism by In Vitro Human Metabolic Enzymes and in Rats* . Journal of Forensic Sciences 57:4, pages 1008-1013.
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Keiko Nakanishi, Akihiro Miki, Kei Zaitsu, Hiroe Kamata, Noriaki Shima, Tooru Kamata, Munehiro Katagi, Michiaki Tatsuno, Hitoshi Tsuchihashi & Koichi Suzuki. (2012) Cross-reactivities of various phenethylamine-type designer drugs to immunoassays for amphetamines, with special attention to the evaluation of the one-step urine drug test Instant-View™, and the Emit® assays for use in drug enforcement. Forensic Science International 217:1-3, pages 174-181.
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Kenji Kuwayama, Kenji Tsujikawa, Hajime Miyaguchi, Tatsuyuki Kanamori, Yuko T. Iwata & Hiroyuki Inoue. (2011) Rapid, simple, and highly sensitive analysis of drugs in biological samples using thin-layer chromatography coupled with matrix-assisted laser desorption/ionization mass spectrometry. Analytical and Bioanalytical Chemistry 402:3, pages 1257-1267.
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Malcolm J. Reid, Katherine H. Langford, Jørg Mørland & Kevin V. Thomas. (2011) Quantitative assessment of time dependent drug-use trends by the analysis of drugs and related metabolites in raw sewage. Drug and Alcohol Dependence 119:3, pages 179-186.
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MARIANA CHERNER, CHAD BOUSMAN, IAN EVERALL, DANIEL BARRON, SCOTT LETENDRE, FLORIN VAIDA, J. HAMPTON ATKINSON, ROBERT HEATON & IGOR GRANT. (2010) Cytochrome P450-2D6 extensive metabolizers are more vulnerable to methamphetamine-associated neurocognitive impairment: Preliminary findings. Journal of the International Neuropsychological Society 16:5, pages 890-901.
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Teresa R Gray, Tamsin Kelly, Linda L LaGasse, Lynne M Smith, Chris Derauf, Penny Grant, Rizwan Shah, Amelia Arria, William Haning, Sheri Della Grotta, Arthur Strauss, Barry M Lester & Marilyn A Huestis. (2010) New Meconium Biomarkers of Prenatal Methamphetamine Exposure Increase Identification of Affected Neonates. Clinical Chemistry 56:5, pages 856-860.
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Teresa R Gray, Tamsin Kelly, Linda L LaGasse, Lynne M Smith, Chris Derauf, William Haning, Penny Grant, Rizwan Shah, Amelia Arria, Arthur Strauss, Barry M Lester & Marilyn A Huestis. (2009) Novel Biomarkers of Prenatal Methamphetamine Exposure in Human Meconium. Therapeutic Drug Monitoring 31:1, pages 70-75.
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Noriaki Shima, Munehiro Katagi & Hitoshi Tsuchihashi. (2009) Direct Analysis of Conjugate Metabolites of Methamphetamine, 3,4-Methylenedioxymethamphetamine, and Their Designer Drugs in Biological Fluids. Journal of Health Science 55:4, pages 495-502.
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Karl B. Scheidweiler, Allan J. Barnes & Marilyn A. Huestis. (2008) A validated gas chromatographic–electron impact ionization mass spectrometric method for methamphetamine, methylenedioxymethamphetamine (MDMA), and metabolites in mouse plasma and brain. Journal of Chromatography B 876:2, pages 266-276.
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Noriaki Shima, Munehiro Katagi, Hiroe Kamata, Kei Zaitsu, Tooru Kamata, Akihiro Miki, Hitoshi Tsuchihashi, Tsutomu Sakuma & Nobuo Nemoto. (2008) Conjugates of p-hydroxymethamphetamine and 4-hydroxy-3-methoxymethamphetamine in blood obtained from methamphetamine and 3,4-methylenedioxymethamphetamine users: analysis by LC-MS-MS. Forensic Toxicology 26:2, pages 58-65.
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Kenji Kuwayama, Hiroyuki Inoue, Tatsuyuki Kanamori, Kenji Tsujikawa, Hajime Miyaguchi, Yuko T. Iwata, Seiji Miyauchi & Naoki Kamo. (2008) Analysis of amphetamine-type stimulants and their metabolites in plasma, urine and bile by liquid chromatography with a strong cation-exchange column-tandem mass spectrometry. Journal of Chromatography B 867:1, pages 78-83.
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Kei Zaitsu, Munehiro Katagi, Tooru Kamata, Hiroe Kamata, Noriaki Shima, Hitoshi Tsuchihashi, Takeshi Hayashi, Hisanaga Kuroki & Ryoji Matoba. (2008) Determination of a newly encountered designer drug “p-methoxyethylamphetamine” and its metabolites in human urine and blood. Forensic Science International 177:1, pages 77-84.
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John T. Cody. 2008. Forensic Science. Forensic Science 127 174 .
Howard Hendrickson, Elizabeth Laurenzana & S. Michael Owens. (2006) Quantitative determination of total methamphetamine and active metabolites in rat tissue by liquid chromatography with tandem mass spectrometric detection. The AAPS Journal 8:4, pages E709-E717.
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