1,964
Views
167
CrossRef citations to date
0
Altmetric
Research Article

Human equilibrative nucleoside transporter (ENT) family of nucleoside and nucleobase transporter proteins

, , , &
Pages 995-1021 | Received 06 Dec 2007, Accepted 17 Jan 2008, Published online: 22 Sep 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (13)

Tejraj V. Janmale, Angus Lindsay & Steven P. Gieseg. (2020) Nucleoside transporters are critical to the uptake and antioxidant activity of 7,8-dihydroneopterin in monocytic cells. Free Radical Research 54:5, pages 341-350.
Read now
Massoud Saidijam, Fatemeh Karimi Dermani, Sareh Sohrabi & Simon G. Patching. (2018) Efflux proteins at the blood–brain barrier: review and bioinformatics analysis. Xenobiotica 48:5, pages 506-532.
Read now
Florian Hinze, Philipp Drewe-Boss, Miha Milek, Uwe Ohler, Markus Landthaler & Michael Gotthardt. (2018) Expanding the map of protein-RNA interaction sites via cell fusion followed by PAR-CLIP. RNA Biology 15:3, pages 359-368.
Read now
Anteneh A. Tesfaye, Mandana Kamgar, Asfar Azmi & Philip A. Philip. (2018) The evolution into personalized therapies in pancreatic ductal adenocarcinoma: challenges and opportunities. Expert Review of Anticancer Therapy 18:2, pages 131-148.
Read now
Ivana Rizzuto, Essam Ghazaly & Godefridus J Peters. (2017) Pharmacological Factors Affecting Accumulation of Gemcitabine’s Active Metabolite, Gemcitabine Triphosphate. Pharmacogenomics 18:9, pages 911-925.
Read now
Christopher J Del Nagro, Jonathan Choi, Yang Xiao, Linda Rangell, Sankar Mohan, Ajay Pandita, Jiping Zha, Peter K. Jackson & Thomas O'Brien. (2014) Chk1 inhibition in p53-deficient cell lines drives rapid chromosome fragmentation followed by caspase-independent cell death. Cell Cycle 13:2, pages 303-314.
Read now
Jung-Suk Choi & Anthony J Berdis. (2012) Nucleoside Transporters: Biological Insights And Therapeutic Applications. Future Medicinal Chemistry 4:11, pages 1461-1478.
Read now
Christopher A Koczor, Rebecca A Torres & William Lewis. (2012) The role of transporters in the toxicity of nucleoside and nucleotide analogs. Expert Opinion on Drug Metabolism & Toxicology 8:6, pages 665-676.
Read now
Olivier Fardel, Elise Kolasa & Marc Le Vee. (2012) Environmental chemicals as substrates, inhibitors or inducers of drug transporters: implication for toxicokinetics, toxicity and pharmacokinetics. Expert Opinion on Drug Metabolism & Toxicology 8:1, pages 29-46.
Read now
German Reyes, Nicole M. I. Nivillac, Muhammad Zia Karim, Leroi Desouza, K. W. Michael Siu & Imogen R. Coe. (2011) The Equilibrative Nucleoside Transporter (ENT1) can be phosphorylated at multiple sites by PKC and PKA. Molecular Membrane Biology 28:6, pages 412-426.
Read now
Ekaitz Errasti-Murugarren & Marçal Pastor-Anglada. (2010) Drug Transporter Pharmacogenetics in Nucleoside-Based Therapies. Pharmacogenomics 11:6, pages 809-841.
Read now
Meryem Köse & Anke C Schiedel. (2009) Nucleoside/Nucleobase Transporters: Drug Targets of the Future?. Future Medicinal Chemistry 1:2, pages 303-326.
Read now

Articles from other publishers (154)

Jose J.G. Marin, Candela Cives-Losada, Rocio I.R. Macias, Marta R. Romero, Rebeca P. Marijuan, Nazaret Hortelano-Hernandez, Kevin Delgado-Calvo, Carmen Villar, Jesus M. Gonzalez-Santiago, Maria J. Monte & Maitane Asensio. (2024) Impact of liver diseases and pharmacological interactions on the transportome involved in hepatic drug disposition. Biochemical Pharmacology, pages 116166.
Crossref
Jang-Ha Ryu, Weizhong Zheng, Xiao-Hong Yang, Hassan Elsaidi, Jim Diakur & Leonard I. Wiebe. (2024) Synthesis and Preliminary Evaluation of an ASGPr-Targeted Polycationic β-Cyclodextrin Carrier for Nucleosides and Nucleotides. Pharmaceutics 16:3, pages 323.
Crossref
Inês Mendes & Nuno Vale. (2024) Overcoming Microbiome-Acquired Gemcitabine Resistance in Pancreatic Ductal Adenocarcinoma. Biomedicines 12:1, pages 227.
Crossref
Hongying Ma, Jian Qu, Yongkang Liao, Linxin Liu, Min Yan, Yiwen Wei, Weixin Xu, Jian Luo, Yuxin Dai, Zicheng Pang & Qiang Qu. (2024) Equilibrative nucleotide transporter ENT3 (SLC29A3): A unique transporter for inherited disorders and cancers. Experimental Cell Research 434:2, pages 113892.
Crossref
Lenka N. C. Boyd, Lynn E. Nooijen, Mahsoem Ali, Jisce R. Puik, Jasmine Moustaquim, Stephanie M. Fraga Rodrigues, Robert Broos, Ali Belkouz, Laura L. Meijer, Tessa Y. S. Le Large, Joris I. Erdmann, Gerrit K. J. Hooijer, Michal Heger, Hanneke W. M. Van Laarhoven, Eva Roos, Geert Kazemier, Elisa Giovannetti, Joanne Verheij & Heinz-Josef Klümpen. (2023) Prognostic and predictive value of human equilibrative nucleoside transporter 1 (hENT1) in extrahepatic cholangiocarcinoma: a translational study. Frontiers in Pharmacology 14.
Crossref
Stefanie A. Baril, Tomoka Gose & John D. Schuetz. (2023) How Cryo-EM Has Expanded Our Understanding of Membrane Transporters. Drug Metabolism and Disposition 51:8, pages 904-922.
Crossref
Anh T. N. Nguyen, Quan L. Tran, Jo-Anne Baltos, Samantha M. McNeill, Diep T. N. Nguyen & Lauren T. May. (2023) Small molecule allosteric modulation of the adenosine A1 receptor. Frontiers in Endocrinology 14.
Crossref
Peifang Qin, Jianguo Yan, Haitao Huang, Qi Wang, Mao Li, Yuting Zhang, Jiahui Wang, Tingting Jiang, Xiaoling Zhang & Yali Zhou. (2023) Equilibrative nucleoside transporter 3 promotes the progression of hepatocellular carcinoma by regulating the AKT/mTOR signaling pathway. International Journal of Biological Macromolecules 241, pages 124323.
Crossref
Tejinder Kaur, Brenna Weadick, Thomas A. Mace, Kajal Desai, Hannah Odom & Rajgopal Govindarajan. (2022) Nucleoside transporters and immunosuppressive adenosine signaling in the tumor microenvironment: Potential therapeutic opportunities. Pharmacology & Therapeutics 240, pages 108300.
Crossref
Chrisanne Dsouza, Mahmoud S. Moussa, Nicholas Mikolajewicz & Svetlana V. Komarova. (2022) Extracellular ATP and its derivatives provide spatiotemporal guidance for bone adaptation to wide spectrum of physical forces. Bone Reports 17, pages 101608.
Crossref
Jessica C. Boakes, Steven. P. D. Harborne, Jessie T. S. Ngo, Christos Pliotas & Adrian Goldman. (2022) Novel variants provide differential stabilisation of human equilibrative nucleoside transporter 1 states. Frontiers in Molecular Biosciences 9.
Crossref
Syed Saqib Ali, Ruchika Raj, Tejinder Kaur, Brenna Weadick, Debasis Nayak, Minnsung No, Jane Protos, Hannah Odom, Kajal Desai, Avinash K. Persaud, Joanne Wang & Rajgopal Govindarajan. (2022) Solute Carrier Nucleoside Transporters in Hematopoiesis and Hematological Drug Toxicities: A Perspective. Cancers 14:13, pages 3113.
Crossref
Rajgopal Govindarajan, Antonio López Quiñones & Joanne Wang. 2022. Drug Transporters. Drug Transporters 165 187 .
Bradley M. Roberts, Elizabeth Lambert, Jessica A. Livesey, Zhaofa Wu, Yulong Li & Stephanie J. Cragg. (2022) Dopamine Release in Nucleus Accumbens Is under Tonic Inhibition by Adenosine A 1 Receptors Regulated by Astrocytic ENT1 and Dysregulated by Ethanol . The Journal of Neuroscience 42:9, pages 1738-1751.
Crossref
Zhixiang Wu, Zhongjie Han, Wenxue Zhou, Xiaohan Sun, Lei Chen, Shuang Yang, Jianping Hu & Chunhua Li. (2022) Insight into the nucleoside transport and inhibition of human ENT1. Current Research in Structural Biology 4, pages 192-205.
Crossref
Karen Aughton, Nils O. Elander, Anthony Evans, Richard Jackson, Fiona Campbell, Eithne Costello, Christopher M. Halloran, John R. Mackey, Andrew G. Scarfe, Juan W. Valle, Ross Carter, David Cunningham, Niall C. Tebbutt, David Goldstein, Jennifer Shannon, Bengt Glimelius, Thilo Hackert, Richard M. Charnley, Alan Anthoney, Markus M. Lerch, Julia Mayerle, Daniel H. Palmer, Markus W. Büchler, Paula Ghaneh, John P. Neoptolemos & William Greenhalf. (2021) hENT1 Predicts Benefit from Gemcitabine in Pancreatic Cancer but Only with Low CDA mRNA. Cancers 13:22, pages 5758.
Crossref
Rohit Batra, Vinay Jain & Pankaj Sharma. (2021) Adenosine: a partially discovered medicinal agent. Future Journal of Pharmaceutical Sciences 7:1.
Crossref
Maryam Fallah, Amirhossein Davoodvandi, Shahin Nikmanzar, Sarehnaz Aghili, Seyed Mohammad Ali Mirazimi, Michael Aschner, Amir Rashidian, Michael R. Hamblin, Mohsen Chamanara, Navid Naghsh & Hamed Mirzaei. (2021) Silymarin (milk thistle extract) as a therapeutic agent in gastrointestinal cancer. Biomedicine & Pharmacotherapy 142, pages 112024.
Crossref
Juan C. Sanchez-Arias, Emma van der Slagt, Haley A. Vecchiarelli, Rebecca C. Candlish, Nicole York, Penelope A. Young, Olga Shevtsova, Afnan Juma, Marie-Ève Tremblay & Leigh Anne Swayne. (2021) Purinergic signaling in nervous system health and disease: Focus on pannexin 1. Pharmacology & Therapeutics 225, pages 107840.
Crossref
Satoru Suzuki, Katsuhisa Inoue, Ikumi Tamai & Yoshiyuki Shirasaka. (2021) Model Analysis of the Apparent Saturation Kinetics of Purine Nucleobase Uptake in Cells co-Expressing Transporter and Metabolic Enzyme. Pharmaceutical Research 38:9, pages 1585-1592.
Crossref
Siennah R. Miller, Thomas R. Lane, Kimberley M. Zorn, Sean Ekins, Stephen H. Wright & Nathan J. Cherrington. (2021) Multiple Computational Approaches for Predicting Drug Interactions with Human Equilibrative Nucleoside Transporter 1. Drug Metabolism and Disposition 49:7, pages 479-489.
Crossref
Nicholas J. Wright & Seok-Yong Lee. (2020) Toward a Molecular Basis of Cellular Nucleoside Transport in Humans. Chemical Reviews 121:9, pages 5336-5358.
Crossref
Avinash K. Persaud, Sreenath Nair, Md Fazlur Rahman, Radhika Raj, Brenna Weadick, Debasis Nayak, Craig McElroy, Muruganandan Shanmugam, Sue Knoblaugh, Xiaolin Cheng & Rajgopal Govindarajan. (2021) Facilitative lysosomal transport of bile acids alleviates ER stress in mouse hematopoietic precursors. Nature Communications 12:1.
Crossref
Arthur G. Roberts. 2021. Enzyme Kinetics in Drug Metabolism. Enzyme Kinetics in Drug Metabolism 193 234 .
Safaa M. Naes, Sharaniza Ab-Rahim, Musalmah Mazlan & Amirah Abdul Rahman. (2020) Equilibrative Nucleoside Transporter 2: Properties and Physiological Roles. BioMed Research International 2020, pages 1-8.
Crossref
Tanzina Mollick & Sonia Laín. (2020) Modulating pyrimidine ribonucleotide levels for the treatment of cancer. Cancer & Metabolism 8:1.
Crossref
Francesca Masetto, Konstantin Chegaev, Elena Gazzano, Nidula Mullappilly, Barbara Rolando, Silvia Arpicco, Roberta Fruttero, Chiara Riganti & Massimo Donadelli. (2020) MRP5 nitration by NO-releasing gemcitabine encapsulated in liposomes confers sensitivity in chemoresistant pancreatic adenocarcinoma cells. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1867:12, pages 118824.
Crossref
Ornella Randazzo, Filippo Papini, Giulia Mantini, Alessandro Gregori, Barbara Parrino, Daniel S. K. Liu, Stella Cascioferro, Daniela Carbone, Godefridus J. Peters, Adam E. Frampton, Ingrid Garajova & Elisa Giovannetti. (2020) “Open Sesame?”: Biomarker Status of the Human Equilibrative Nucleoside Transporter-1 and Molecular Mechanisms Influencing its Expression and Activity in the Uptake and Cytotoxicity of Gemcitabine in Pancreatic Cancer. Cancers 12:11, pages 3206.
Crossref
Hiroaki Yuasa, Tomoya Yasujima & Katsuhisa Inoue. (2020) Current Understanding of the Intestinal Absorption of Nucleobases and Analogs. Biological and Pharmaceutical Bulletin 43:9, pages 1293-1300.
Crossref
Risa Takenaka, Tomoya Yasujima, Junji Furukawa, Yosuke Hishikawa, Takahiro Yamashiro, Kinya Ohta, Katsuhisa Inoue & Hiroaki Yuasa. (2020) Functional Analysis of the Role of Equilibrative Nucleobase Transporter 1 (ENBT1/SLC43A3) in Adenine Transport in HepG2 Cells. Journal of Pharmaceutical Sciences 109:8, pages 2622-2628.
Crossref
Alireza Rezvani, Erfan Taherifard, Maral Mokhtari, Afrooz Feili & Hamed Movahed. (2020) H syndrome with a possibly new immunological phenotype. International Journal of Dermatology 59:7.
Crossref
Erich H. Schneider, Olga Hofmeister, Solveig Kälble & Roland Seifert. (2020) Apoptotic and anti-proliferative effect of guanosine and guanosine derivatives in HuT-78 T lymphoma cells. Naunyn-Schmiedeberg's Archives of Pharmacology 393:7, pages 1251-1267.
Crossref
Rui Pinto-Cardoso, Flávio Pereira-Costa, João Pedro Faria, Patrícia Bandarrinha, Catarina Bessa-Andrês, Paulo Correia-de-Sá & José Bernardo Noronha-Matos. (2020) Adenosinergic signalling in chondrogenesis and cartilage homeostasis: Friend or foe?. Biochemical Pharmacology 174, pages 113784.
Crossref
Yin-Xin Zhu, Chi Han Li, Guolin Li, Huiyi Feng, Tian Xia, Chi Hin Wong, Frederic Khe Cheong Fung, Joanna Hung-Man Tong, Ka-Fai To, Rufu Chen & Yangchao Chen. (2020) LLGL1 Regulates Gemcitabine Resistance by Modulating the ERK-SP1-OSMR Pathway in Pancreatic Ductal Adenocarcinoma. Cellular and Molecular Gastroenterology and Hepatology 10:4, pages 811-828.
Crossref
Shahid Rehan, Saman Shahid, Tiina A. Salminen, Veli-Pekka Jaakola & Ville O. Paavilainen. (2019) Current Progress on Equilibrative Nucleoside Transporter Function and Inhibitor Design. SLAS Discovery 24:10, pages 953-968.
Crossref
Katsuya Narumi, Tsukika Ohata, Yuichi Horiuchi, Hiroshi Satoh, Ayako Furugen, Masaki Kobayashi & Ken Iseki. (2019) Mutual role of ecto-5'-nucleotidase/CD73 and concentrative nucleoside transporter 3 in the intestinal uptake of dAMP. PLOS ONE 14:10, pages e0223892.
Crossref
Matthew A. Veras, Neil A. Tenn, Miljan Kuljanin, Gilles A. Lajoie, James R. Hammond, S. Jeffrey Dixon & Cheryle A. Séguin. (2019) Loss of ENT1 increases cell proliferation in the annulus fibrosus of the intervertebral disc. Journal of Cellular Physiology 234:8, pages 13705-13719.
Crossref
Nicholas J. Wright & Seok-Yong Lee. (2019) Structures of human ENT1 in complex with adenosine reuptake inhibitors. Nature Structural & Molecular Biology 26:7, pages 599-606.
Crossref
Rita Bagherian, Farideh Yousefipour, Houriyeh Sadat Mousavi, Fatemeh Saffari, Elham HajiShafieha, Samin Nesbat Mohammadi, Hadi Mousakhani, Seyed Mohammad Fathi, Amirhossein Mehrtash, Fatemeh Masomi Verki, Donghyun Lee & Abolfazl Heidari. (2019) Identification of a novel homozygous frameshift mutation in SLC29A3 gene in a case with H syndrome from Iran. Current Research in Translational Medicine 67:2, pages 72-75.
Crossref
Kashika Arora & Ambak Kumar Rai. (2018) Dependence of Leishmania parasite on host derived ATP: an overview of extracellular nucleotide metabolism in parasite. Journal of Parasitic Diseases 43:1, pages 1-13.
Crossref
Nahid Askari, Elham Rezvannejad, Sodaif Darvish Moghadam & Sara Shafieipour. (2019) Structural analysis of misfolding equilibrative nucleoside transporter 3in H-syndrome. Journal of Molecular Structure 1177, pages 177-185.
Crossref
Sylvia Y.M. Yao, Amy M.L. Ng, Carol E. Cass & James D. Young. (2018) Role of cysteine 416 in N -ethylmaleimide sensitivity of human equilibrative nucleoside transporter 1 (hENT1) . Biochemical Journal 475:20, pages 3293-3309.
Crossref
MD Fazlur Rahman, Radhika Raj & Rajgopal Govindarajan. (2018) Identification of Structural and Molecular Features Involved in the Transport of 3′-Deoxy-Nucleoside Analogs by Human Equilibrative Nucleoside Transporter 3. Drug Metabolism and Disposition 46:5, pages 600-609.
Crossref
N. O. Elander, K. Aughton, P. Ghaneh, J. P. Neoptolemos, D. H. Palmer, T. F. Cox, F. Campbell, E. Costello, C. M. Halloran, J. R. Mackey, A. G Scarfe, J. W. Valle, A. C. McDonald, R. Carter, N. C. Tebbutt, D. Goldstein, J. Shannon, C. Dervenis, B. Glimelius, M. Deakin, R. M. Charnley, Alan Anthoney, M. M. Lerch, J. Mayerle, A. Oláh, M. W. Büchler & W. Greenhalf. (2018) Expression of dihydropyrimidine dehydrogenase (DPD) and hENT1 predicts survival in pancreatic cancer. British Journal of Cancer 118:7, pages 947-954.
Crossref
Kazuaki Matsuoka, Fumio Nakagawa, Takashi Kobunai & Teiji Takechi. (2018) Trifluridine/tipiracil overcomes the resistance of human gastric 5-fluorouracil-refractory cells with high thymidylate synthase expression. Oncotarget 9:17, pages 13438-13450.
Crossref
Vassilis L. Tzounakas, Federica Gevi, Hara T. Georgatzakou, Lello Zolla, Issidora S. Papassideri, Anastasios G. Kriebardis, Sara Rinalducci & Marianna H. Antonelou. (2018) Redox Status, Procoagulant Activity, and Metabolome of Fresh Frozen Plasma in Glucose 6-Phosphate Dehydrogenase Deficiency. Frontiers in Medicine 5.
Crossref
Laura PurdieCameron Alexander, Sebastian G. Spain & Johannes P. Magnusson. (2018) Alkyl-Modified Oligonucleotides as Intercalating Vehicles for Doxorubicin Uptake via Albumin Binding. Molecular Pharmaceutics 15:2, pages 437-446.
Crossref
Qiuying Ye, Ge Li, Shuhua Liu, Yalun Guan, Yunfeng Li, Jinling Li, Huanhuan Jia, Xuejiao Li, Qingnan Li, Ren Huang, Hui Wang & Yu Zhang. (2018) Targeted disruption of adenosine kinase in myeloid monocyte cells increases osteoclastogenesis and bone resorption in mice. International Journal of Molecular Medicine.
Crossref
K.K. Wolf & M.F. Paine. 2018. Comprehensive Toxicology. Comprehensive Toxicology 74 98 .
Judith E K Henning, Timo Deutschbein, Barbara Altieri, Sonja Steinhauer, Stefan Kircher, Silviu Sbiera, Vanessa Wild, Wiebke Schlötelburg, Matthias Kroiss, Paola Perotti, Andreas Rosenwald, Alfredo Berruti, Martin Fassnacht & Cristina L Ronchi. (2017) Gemcitabine-Based Chemotherapy in Adrenocortical Carcinoma: A Multicenter Study of Efficacy and Predictive Factors. The Journal of Clinical Endocrinology & Metabolism 102:11, pages 4323-4332.
Crossref
Mahmoud H. el Kouni. (2017) Pyrimidine metabolism in schistosomes: A comparison with other parasites and the search for potential chemotherapeutic targets. Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 213, pages 55-80.
Crossref
Md Fazlur Rahman, Candice Askwith & Rajgopal Govindarajan. (2017) Molecular determinants of acidic pH-dependent transport of human equilibrative nucleoside transporter 3. Journal of Biological Chemistry 292:36, pages 14775-14785.
Crossref
Anton Ivanyuk, Françoise Livio, Jérôme Biollaz & Thierry Buclin. (2017) Renal Drug Transporters and Drug Interactions. Clinical Pharmacokinetics 56:8, pages 825-892.
Crossref
Ras Mulinta, Sylvia Y.M. Yao, Amy M.L. Ng, Carol E. Cass & James D. Young. (2017) Substituted cysteine accessibility method (SCAM) analysis of the transport domain of human concentrative nucleoside transporter 3 (hCNT3) and other family members reveals features of structural and functional importance. Journal of Biological Chemistry 292:23, pages 9505-9522.
Crossref
Andrea Leiva, Enrique Guzmán-Gutiérrez, Susana Contreras-Duarte, Bárbara Fuenzalida, Claudette Cantin, Lorena Carvajal, Rocío Salsoso, Jaime Gutiérrez, Fabián Pardo & Luis Sobrevia. (2017) Adenosine receptors: Modulators of lipid availability that are controlled by lipid levels. Molecular Aspects of Medicine 55, pages 26-44.
Crossref
Patricia Giuliani, Mariachiara Zuccarini, Silvana Buccella, Luis Emiliano Peña‐Altamira, Elisabetta Polazzi, Marco Virgili, Barbara Monti, Alessandro Poli, Michel P. Rathbone, Patrizia Di Iorio, Renata Ciccarelli & Francesco Caciagli. (2017) Evidence for purine nucleoside phosphorylase (PNP) release from rat C6 glioma cells. Journal of Neurochemistry 141:2, pages 208-221.
Crossref
Justine M. Grixti, Steve O'Hagan, Philip J. Day & Douglas B. Kell. (2017) Enhancing Drug Efficacy and Therapeutic Index through Cheminformatics-Based Selection of Small Molecule Binary Weapons That Improve Transporter-Mediated Targeting: A Cytotoxicity System Based on Gemcitabine. Frontiers in Pharmacology 8.
Crossref
Rana Yadak, Peter Sillevis Smitt, Marike W. van Gisbergen, Niek P. van Til & Irenaeus F. M. de Coo. (2017) Mitochondrial Neurogastrointestinal Encephalomyopathy Caused by Thymidine Phosphorylase Enzyme Deficiency: From Pathogenesis to Emerging Therapeutic Options. Frontiers in Cellular Neuroscience 11.
Crossref
Yolanda Durán-Medina, David Díaz-Ramírez & Nayelli Marsch-Martínez. (2017) Cytokinins on the Move. Frontiers in Plant Science 8.
Crossref
Emelie Perland, Sofie V. Hellsten, Emilia Lekholm, Mikaela M. Eriksson, Vasiliki Arapi & Robert Fredriksson. (2016) The Novel Membrane-Bound Proteins MFSD1 and MFSD3 are Putative SLC Transporters Affected by Altered Nutrient Intake. Journal of Molecular Neuroscience 61:2, pages 199-214.
Crossref
Radim Moravec, Rao Divi & Mukesh Verma. (2017) Detecting circulating tumor material and digital pathology imaging during pancreatic cancer progression. World Journal of Gastrointestinal Oncology 9:6, pages 235.
Crossref
Katsuhisa Inoue. (2017) Molecular Basis of Nucleobase Transport Systems in Mammals. Biological & Pharmaceutical Bulletin Biological and Pharmaceutical Bulletin 40:8, pages 1130-1138.
Crossref
Lauren C. Strazzulla & Bruce N. Cronstein. (2016) Regulation of bone and cartilage by adenosine signaling. Purinergic Signalling 12:4, pages 583-593.
Crossref
Hisataka Ii, Sumeeta Warraich, Neil Tenn, Diana Quinonez, David W. Holdsworth, James R. Hammond, S. Jeffrey Dixon & Cheryle A. Séguin. (2016) Disruption of biomineralization pathways in spinal tissues of a mouse model of diffuse idiopathic skeletal hyperostosis. Bone 90, pages 37-49.
Crossref
Mitesh Patel, Kunal S. Taskar & Maciej J. Zamek‐Gliszczynski. (2016) Importance of Hepatic Transporters in Clinical Disposition of Drugs and Their Metabolites. The Journal of Clinical Pharmacology 56:S7.
Crossref
James D. Young. (2016) The SLC28 (CNT) and SLC29 (ENT) nucleoside transporter families: a 30-year collaborative odyssey. Biochemical Society Transactions 44:3, pages 869-876.
Crossref
A. Bakhchane, Z. Kindil, H. Charoute, K. Benchikhi, K. Khadir, S. Nadifi, K. Baline, R. Roky & A. Barakat. (2016) Compound heterozygous SLC29A3 mutation causes H syndrome in a Moroccan patient: A case report. Current Research in Translational Medicine 64:2, pages 65-68.
Crossref
G. Daniels. (2016) The Augustine blood group system, 48 years in the making. Immunohematology 32:3, pages 100-103.
Crossref
Mohammad Al-Ansari & James D. Craik. (2015) Decreased erythrocyte nucleoside transport and hENT1 transporter expression in glucose 6-phosphate dehydrogenase deficiency. BMC Hematology 15:1.
Crossref
Kristina K. Wolf, Brandon T. Gufford, Scott J. Brantley, Paul B. Watkins & Mary F. Paine. 2015. Yamada' s Textbook of Gastroenterology. Yamada' s Textbook of Gastroenterology 626 638 .
Junji Furukawa, Katsuhisa Inoue, Junya Maeda, Tomoya Yasujima, Kinya Ohta, Yoshikatsu Kanai, Tappei Takada, Hirotaka Matsuo & Hiroaki Yuasa. (2015) Functional identification of SLC43A3 as an equilibrative nucleobase transporter involved in purine salvage in mammals. Scientific Reports 5:1.
Crossref
B. Liu, A. Czajka, A.N. Malik, K. Hussain, P.M. Jones & S.J. Persaud. (2015) Equilibrative nucleoside transporter 3 depletion in β-cells impairs mitochondrial function and promotes apoptosis: Relationship to pigmented hypertrichotic dermatosis with insulin-dependent diabetes. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1852:10, pages 2086-2095.
Crossref
Felicia Tsang & Su-Ju Lin. (2015) Less is more: Nutrient limitation induces cross-talk of nutrient sensing pathways with NAD+ homeostasis and contributes to longevity. Frontiers in Biology 10:4, pages 333-357.
Crossref
Geoff DanielsBryan A. BallifVirginie HeliasCarole SaisonShane GrimsleyLucienne MannessierHein HustinxEdmond Lee, Jean-Pierre CartronThierry Peyrard & Lionel Arnaud. (2015) Lack of the nucleoside transporter ENT1 results in the Augustine-null blood type and ectopic mineralization. Blood 125:23, pages 3651-3654.
Crossref
Mohammad Al-Haggar, Nanees Salem, Yahya Wahba, Nermin Ahmad, Laurence Jonard, Dina Abdel-Hady, Amany El-Hawary, Ashraf El-Sharkawy, Abdel-Rhman Eid & Amira El-Hawary. (2015) Novel homozygous SLC29A3 mutations among two unrelated Egyptian families with spectral features of H-syndrome . Pediatric Diabetes 16:4, pages 305-316.
Crossref
Felicia Tsang, Christol James, Michiko Kato, Victoria Myers, Irtqa Ilyas, Matthew Tsang & Su-Ju Lin. (2015) Reduced Ssy1-Ptr3-Ssy5 (SPS) Signaling Extends Replicative Life Span by Enhancing NAD+ Homeostasis in Saccharomyces cerevisiae. Journal of Biological Chemistry 290:20, pages 12753-12764.
Crossref
Scott J. Hughes, Xenia Cravetchi, Gonzalo Vilas & James R. Hammond. (2015) Adenosine A1 receptor activation modulates human equilibrative nucleoside transporter 1 (hENT1) activity via PKC-mediated phosphorylation of serine-281. Cellular Signalling 27:5, pages 1008-1018.
Crossref
I. J. Frame, Roman Deniskin, Avish Arora & Myles H. Akabas. (2014) Purine import into malaria parasites as a target for antimalarial drug development. Annals of the New York Academy of Sciences 1342:1, pages 19-28.
Crossref
D. Thimm, A. C. Schiedel, J. Peti‐Peterdi, B. K. Kishore & C. E. Müller. (2015) The nucleobase adenine as a signalling molecule in the kidney. Acta Physiologica 213:4, pages 808-818.
Crossref
Jung-Suk Choi, Ayan Maity, Thomas Gray & Anthony J. Berdis. (2015) A Metal-containing Nucleoside That Possesses Both Therapeutic and Diagnostic Activity against Cancer. Journal of Biological Chemistry 290:15, pages 9714-9726.
Crossref
I. J. Frame, Roman Deniskin, Alison Rinderspacher, Francine Katz, Shi-Xian Deng, Robyn D. Moir, Sophie H. Adjalley, Olivia Coburn-Flynn, David A. Fidock, Ian M. Willis, Donald W. Landry & Myles H. Akabas. (2015) Yeast-Based High-Throughput Screen Identifies Plasmodium falciparum Equilibrative Nucleoside Transporter 1 Inhibitors That Kill Malaria Parasites . ACS Chemical Biology 10:3, pages 775-783.
Crossref
Bruno Stieger & Bo Gao. (2015) Drug Transporters in the Central Nervous System. Clinical Pharmacokinetics 54:3, pages 225-242.
Crossref
Marçal Pastor-Anglada & Sandra Pérez-Torras. (2015) Nucleoside transporter proteins as biomarkers of drug responsiveness and drug targets. Frontiers in Pharmacology 6.
Crossref
Michael P Chu, Vijaya L Damaraju & Michael B Sawyer. (2015) Challenges of combining cytotoxic chemotherapy and tyrosine kinase inhibitors. Clinical Investigation 5:1, pages 39-46.
Crossref
Hilaire Playa, Timothy A. Lewis, Amal Ting, Byung-Chul Suh, Benito Muñoz, Robert Matuza, Brent J. Passer, Stuart L. Schreiber & John K. Buolamwini. (2014) Dilazep analogues for the study of equilibrative nucleoside transporters 1 and 2 (ENT1 and ENT2). Bioorganic & Medicinal Chemistry Letters 24:24, pages 5801-5804.
Crossref
Michiko Kato & Su-Ju Lin. (2014) Regulation of NAD+ metabolism, signaling and compartmentalization in the yeast Saccharomyces cerevisiae. DNA Repair 23, pages 49-58.
Crossref
David J. Hinton, Moonnoh R. Lee, Jin Sung Jang & Doo‐Sup Choi. (2014) Type 1 equilibrative nucleoside transporter regulates astrocyte‐specific glial fibrillary acidic protein expression in the striatum. Brain and Behavior 4:6, pages 903-914.
Crossref
Horace T. B. Ho & Joanne Wang. 2014. Drug Transporters. Drug Transporters 107 126 .
Tamima Ashraf, Patrick T. Ronaldson & Reina Bendayan. 2014. Drug Transporters. Drug Transporters 273 301 .
Alexandre dos Santos-Rodrigues, Natalia Grañé-Boladeras, Alex Bicket & Imogen R. Coe. (2014) Nucleoside transporters in the purinome. Neurochemistry International 73, pages 229-237.
Crossref
Michiko Kato & Su-Ju Lin. (2014) YCL047C/POF1 Is a Novel Nicotinamide Mononucleotide Adenylyltransferase (NMNAT) in Saccharomyces cerevisiae. Journal of Biological Chemistry 289:22, pages 15577-15587.
Crossref
Raquel Valdés, Johannes Elferich, Ujwal Shinde & Scott M. Landfear. (2014) Identification of the Intracellular Gate for a Member of the Equilibrative Nucleoside Transporter (ENT) Family. Journal of Biological Chemistry 289:13, pages 8799-8809.
Crossref
Bertil B. Fredholm. (2013) Adenosine—a physiological or pathophysiological agent?. Journal of Molecular Medicine 92:3, pages 201-206.
Crossref
David J. Hinton, Meghan E. McGee-Lawrence, Moonnoh R. Lee, Hoi K. Kwong, Jennifer J. Westendorf & Doo-Sup Choi. (2014) Aberrant Bone Density in Aging Mice Lacking the Adenosine Transporter ENT1. PLoS ONE 9:2, pages e88818.
Crossref
Tomomi Furihata, Misa Mizuguchi, Yuki Suzuki, Shogo Matsumoto, Kaoru Kobayashi & Kan Chiba. (2014) Identification of Primary Equilibrative Nucleoside Transporter 1 mRNA Isoforms Resulting from Alternative Promoter Usage in Human Hepatocytes. Drug Metabolism and Pharmacokinetics 29:4, pages 325-332.
Crossref
William Greenhalf, Paula Ghaneh, John P. Neoptolemos, Daniel H. Palmer, Trevor F. Cox, Richard F. Lamb, Elizabeth Garner, Fiona Campbell, John R. Mackey, Eithne Costello, Malcolm J. Moore, Juan W. Valle, Alexander C. McDonald, Ross Carter, Niall C. Tebbutt, David Goldstein, Jennifer Shannon, Christos Dervenis, Bengt Glimelius, Mark Deakin, Richard M. Charnley, François Lacaine, Andrew G. Scarfe, Mark R. Middleton, Alan Anthoney, Christopher M. Halloran, Julia Mayerle, Attila Oláh, Richard Jackson, Charlotte L. Rawcliffe, Aldo Scarpa, Claudio Bassi & Markus W. Büchler. (2014) Pancreatic Cancer hENT1 Expression and Survival From Gemcitabine in Patients From the ESPAC-3 Trial. JNCI: Journal of the National Cancer Institute 106:1.
Crossref
Tamima Ashraf, Amy Kao & Reina Bendayan. 2014. Pharmacology of the Blood Brain Barrier: Targeting CNS Disorders. Pharmacology of the Blood Brain Barrier: Targeting CNS Disorders 45 111 .
Richard H. Ho & Richard B. Kim. 2014. Handbook of Anticancer Pharmacokinetics and Pharmacodynamics. Handbook of Anticancer Pharmacokinetics and Pharmacodynamics 401 442 .
Vijaya L. DamarajuDelores MowlesMarnie WilsonMichelle KuzmaCarol E. CassMichael B. Sawyer. (2013) Comparative in vitro evaluation of transportability and toxicity of capecitabine and its metabolites in cells derived from normal human kidney and renal cancers. Biochemistry and Cell Biology 91:6, pages 419-427.
Crossref
Jackelyn Golden, Edward Motea, Xuemei Zhang, Jung-Suk Choi, Ye Feng, Yan Xu, Irene Lee & Anthony J. Berdis. (2013) Development and Characterization of a Non-natural Nucleoside that Displays Anticancer Activity Against Solid Tumors. ACS Chemical Biology 8:11, pages 2452-2465.
Crossref
Gregorio Gomez, Vincent Nardone, Sahar Lotfi-Emran, Wei Zhao & Lawrence B. Schwartz. (2013) Intracellular Adenosine Inhibits IgE-Dependent Degranulation of Human Skin Mast Cells. Journal of Clinical Immunology 33:8, pages 1349-1359.
Crossref
Elodie Robin, Jessica Sabourin, Fabrice Marcillac & Eric Raddatz. (2013) Involvement of CD73, equilibrative nucleoside transporters and inosine in rhythm and conduction disturbances mediated by adenosine A1 and A2A receptors in the developing heart. Journal of Molecular and Cellular Cardiology 63, pages 14-25.
Crossref
Cassandra S. Arendt. (2013) Crithidia fasciculata adenosine transporter 1 (CfAT1), a novel high-affinity equilibrative nucleoside transporter specific for adenosine. Molecular and Biochemical Parasitology 191:2, pages 75-79.
Crossref
Wenjie He, Amitabha Mazumder, Tuere Wilder & Bruce N. Cronstein. (2013) Adenosine regulates bone metabolism via A 1 , A 2A , and A 2B receptors in bone marrow cells from normal humans and patients with multiple myeloma . The FASEB Journal 27:9, pages 3446-3454.
Crossref
K M Hillgren, D Keppler, A A Zur, K M Giacomini, B Stieger, C E Cass & L Zhang. (2013) Emerging Transporters of Clinical Importance: An Update From the International Transporter Consortium. Clinical Pharmacology & Therapeutics 94:1, pages 52-63.
Crossref
Eve-Irene Lepist, Vijaya L. Damaraju, Jing Zhang, Wendy P. Gati, Sylvia Y.M. Yao, Kyla M. Smith, Edward Karpinski, James D. Young, Kwan H. Leung & Carol E. Cass. (2013) Transport of A 1 Adenosine Receptor Agonist Tecadenoson by Human and Mouse Nucleoside Transporters: Evidence for Blood-Brain Barrier Transport by Murine Equilibrative Nucleoside Transporter 1 mENT1 . Drug Metabolism and Disposition 41:4, pages 916-922.
Crossref
James D. Young, Sylvia Y.M. Yao, Jocelyn M. Baldwin, Carol E. Cass & Stephen A. Baldwin. (2013) The human concentrative and equilibrative nucleoside transporter families, SLC28 and SLC29. Molecular Aspects of Medicine 34:2-3, pages 529-547.
Crossref
Rachel A. Kudgus, Annamaria Szabolcs, Jameel Ahmad Khan, Chad A. Walden, Joel M. Reid, J. David Robertson, Resham Bhattacharya & Priyabrata Mukherjee. (2013) Inhibiting the Growth of Pancreatic Adenocarcinoma In Vitro and In Vivo through Targeted Treatment with Designer Gold Nanotherapeutics. PLoS ONE 8:3, pages e57522.
Crossref
Edwin K. Jackson, Dongmei Cheng, Travis C. Jackson, Jonathan D. Verrier & Delbert G. Gillespie. (2013) Extracellular guanosine regulates extracellular adenosine levels. American Journal of Physiology-Cell Physiology 304:5, pages C406-C421.
Crossref
Moonnoh R Lee, Christina L Ruby, David J Hinton, Sun Choi, Chelsea A Adams, Na Young Kang & Doo-Sup Choi. (2012) Striatal Adenosine Signaling Regulates EAAT2 and Astrocytic AQP4 Expression and Alcohol Drinking in Mice. Neuropsychopharmacology 38:3, pages 437-445.
Crossref
Zhiwei Feng, Tingjun Hou & Youyong Li. (2013) Transport of nucleosides in the vcCNT facilitated by sodium gradients from molecular dynamics simulations. Molecular BioSystems 9:8, pages 2142.
Crossref
Tamima Ashraf, Olena Kis, Nilasha Banerjee & Reina Bendayan. 2013. Biology and Regulation of Blood-Tissue Barriers. Biology and Regulation of Blood-Tissue Barriers 20 69 .
Raquel Valdés, Ujwal Shinde & Scott M. Landfear. (2012) Cysteine Cross-linking Defines the Extracellular Gate for the Leishmania donovani Nucleoside Transporter 1.1 (LdNT1.1). Journal of Biological Chemistry 287:53, pages 44036-44045.
Crossref
I. J. FrameEmilio F. MerinoVern L. SchrammMaría B. CasseraMyles H. Akabas. (2012) Malaria parasite type 4 equilibrative nucleoside transporters (ENT4) are purine transporters with distinct substrate specificity. Biochemical Journal 446:2, pages 179-190.
Crossref
Ross Corriden & Paul A. Insel. (2012) New insights regarding the regulation of chemotaxis by nucleotides, adenosine, and their receptors. Purinergic Signalling 8:3, pages 587-598.
Crossref
Pedro Cano‐Soldado & Marçal Pastor‐Anglada. (2011) Transporters that translocate nucleosides and structural similar drugs: structural requirements for substrate recognition. Medicinal Research Reviews 32:2, pages 428-457.
Crossref
Chia-Lin HsuWeiyu LinDhaya SeshasayeeYung-Hsiang ChenXiao DingZhonghua LinEric SutoZhiyu HuangWyne P. LeeHyunjoo ParkMin XuMei SunLinda RangellJeff L. LutmanSheila UlufatuEric StefanichCecile ChalouniMeredith SagollaLauri DiehlPaul FielderBrian DeanMercedesz BalazsFlavius Martin. (2012) Equilibrative Nucleoside Transporter 3 Deficiency Perturbs Lysosome Function and Macrophage Homeostasis. Science 335:6064, pages 89-92.
Crossref
Alexandre Bolze, Avinash Abhyankar, Audrey V. Grant, Bhavi Patel, Ruchi Yadav, Minji Byun, Daniel Caillez, Jean-Francois Emile, Marçal Pastor-Anglada, Laurent Abel, Anne Puel, Rajgopal Govindarajan, Loic de Pontual & Jean-Laurent Casanova. (2012) A Mild Form of SLC29A3 Disorder: A Frameshift Deletion Leads to the Paradoxical Translation of an Otherwise Noncoding mRNA Splice Variant. PLoS ONE 7:1, pages e29708.
Crossref
Pedro Cano-SoldadoEdurne Gorraitz, Ekaitz Errasti-MurugarrenF. Javier CasadoM. Pilar Lostao & Marçal Pastor-Anglada. (2012) Functional analysis of the human concentrative nucleoside transporter-1 variant hCNT1S546P provides insight into the sodium-binding pocket. American Journal of Physiology-Cell Physiology 302:1, pages C257-C266.
Crossref
Vijaya L. Damaraju, Delores Mowles, Kyla M. Smith, Sylvia Y. M. Yao, James D. Young, Victor E. Marquez & Carol E. Cass. (2011) Influence of Sugar Ring Conformation on the Transportability of Nucleosides by Human Nucleoside Transporters. ChemBioChem 12:18, pages 2774-2778.
Crossref
Ekaitz Errasti-Murugarren, Paula Díaz, Valeria Godoy, Gloria Riquelme & Marçal Pastor-Anglada. (2011) Expression and Distribution of Nucleoside Transporter Proteins in the Human Syncytiotrophoblast. Molecular Pharmacology 80:5, pages 809-817.
Crossref
Jennifer B. Rose, Zlatina Naydenova, Andrew Bang, Azza Ramadan, Jost Klawitter, Kristin Schram, Gary Sweeney, Almut Grenz, Holger Eltzschig, James Hammond, Doo-Sup Choi & Imogen R. Coe. (2011) Absence of equilibrative nucleoside transporter 1 in ENT1 knockout mice leads to altered nucleoside levels following hypoxic challenge. Life Sciences 89:17-18, pages 621-630.
Crossref
Jennifer L. Spratlin & Karen E. Mulder. (2011) Looking to the Future: Biomarkers in the Management of Pancreatic Adenocarcinoma. International Journal of Molecular Sciences 12:9, pages 5895-5907.
Crossref
Edwena D. Miles, Yan Xue, James R. Strickland, James A. Boling & James C. Matthews. (2011) Ergopeptines Bromocriptine and Ergovaline and the Dopamine Type-2 Receptor Inhibitor Domperidone Inhibit Bovine Equilibrative Nucleoside Transporter 1-like Activity. Journal of Agricultural and Food Chemistry 59:17, pages 9691-9699.
Crossref
Sylvia Y.M. Yao, Amy M.L. Ng, Carol E. Cass, Stephen A. Baldwin & James D. Young. (2011) Nucleobase Transport by Human Equilibrative Nucleoside Transporter 1 (hENT1). Journal of Biological Chemistry 286:37, pages 32552-32562.
Crossref
Sue Ping Lim, Paul Neilsen, Raman Kumar, Andrew Abell & David F. Callen. (2011) The Application of Delivery Systems for DNA Methyltransferase Inhibitors. BioDrugs 25:4, pages 227-242.
Crossref
Ramzi Shawahna, Yasuo Uchida, Xavier Declèves, Sumio Ohtsuki, Salah Yousif, Sandrine Dauchy, Aude Jacob, Francine Chassoux, Catherine Daumas-Duport, Pierre-Olivier Couraud, Tetsuya Terasaki & Jean-Michel Scherrmann. (2011) Transcriptomic and Quantitative Proteomic Analysis of Transporters and Drug Metabolizing Enzymes in Freshly Isolated Human Brain Microvessels. Molecular Pharmaceutics 8:4, pages 1332-1341.
Crossref
I. Novak. (2011) Purinergic signalling in epithelial ion transport: regulation of secretion and absorption. Acta Physiologica 202:3, pages 501-522.
Crossref
Wenwei Lin & John K. Buolamwini. (2011) Design, Synthesis, and Evaluation of 2-Diethanolamino-4,8-diheptamethyleneimino-2-( N -aminoethyl- N -ethanolamino)-6-( N,N -diethanolamino)pyrimido[5,4- d ]pyrimidine-fluorescein Conjugate (8MDP-fluor), As a Novel Equilibrative Nucleoside Transporter Probe . Bioconjugate Chemistry 22:6, pages 1221-1227.
Crossref
German ReyesNicole M.I. NivillacMaria ChalsevImogen R. Coe. (2011) Analysis of recombinant tagged equilibrative nucleoside transporter 1 (ENT1) expressed in E. coli This paper is one of a selection of papers published in a Special Issue entitled CSBMCB 53rd Annual Meeting — Membrane Proteins in Health and Disease, and has undergone the Journal’s usual peer review process. . Biochemistry and Cell Biology 89:2, pages 246-255.
Crossref
Kathryn GrahamSylvia YaoLorelei JohnsonDelores MowlesAmy NgJodi WilkinsonJames D. YoungCarol E. Cass. (2011) Nucleoside transporter gene expression in wild-type and mENT1 knockout miceThis paper is one of a selection of papers published in a Special Issue entitled CSBMCB 53rd Annual Meeting — Membrane Proteins in Health and Disease, and has undergone the Journal’s usual peer review process.. Biochemistry and Cell Biology 89:2, pages 236-245.
Crossref
Shu-Ping Lu & Su-Ju Lin. (2011) Phosphate-responsive Signaling Pathway Is a Novel Component of NAD+ Metabolism in Saccharomyces cerevisiae. Journal of Biological Chemistry 286:16, pages 14271-14281.
Crossref
Akiko Ohashi, Yuko Sugawara, Kaori Mamada, Yoshinori Harada, Tomomi Sumi, Naohiko Anzai, Shin Aizawa & Hiroyuki Hasegawa. (2011) Membrane transport of sepiapterin and dihydrobiopterin by equilibrative nucleoside transporters: A plausible gateway for the salvage pathway of Tetrahydrobiopterin biosynthesis. Molecular Genetics and Metabolism 102:1, pages 18-28.
Crossref
Jennifer L. Spratlin & John R. Mackey. (2010) Human Equilibrative Nucleoside Transporter 1 (hENT1) in Pancreatic Adenocarcinoma: Towards Individualized Treatment Decisions. Cancers 2:4, pages 2044-2054.
Crossref
Sylvine Cottin, Karim Ghani, Pedro Otavio de Campos-Lima & Manuel Caruso. (2010) Gemcitabine intercellular diffusion mediated by gap junctions: new implications for cancer therapy. Molecular Cancer 9:1.
Crossref
Melissa Marvi, Jennifer B. Rose, Andrew Bang, Byung Choo Moon, Zlatko Pozeg, Moheb Ibrahim, Charles Peniston & Imogen R. Coe. (2010) Nucleoside transporter expression profiles in human cardiac tissue show striking individual variability with overall predominance of hENT1. European Journal of Pharmaceutical Sciences 41:5, pages 685-691.
Crossref
Mingyan Zhou, Haichuan Duan, Karen Engel, Li Xia & Joanne Wang. (2010) Adenosine Transport by Plasma Membrane Monoamine Transporter: Reinvestigation and Comparison with Organic Cations. Drug Metabolism and Disposition 38:10, pages 1798-1805.
Crossref
Nayoung Kang, Ah Hyun Jun, Yangzom Doma Bhutia, Natarajan Kannan, Jashvant D. Unadkat & Rajgopal Govindarajan. (2010) Human Equilibrative Nucleoside Transporter-3 (hENT3) Spectrum Disorder Mutations Impair Nucleoside Transport, Protein Localization, and Stability. Journal of Biological Chemistry 285:36, pages 28343-28352.
Crossref
German Reyes, Zlatina Naydenova, Parween Abdulla, Maria Chalsev, Anita Villani, Jennifer B. Rose, Naz Chaudary, Leroi DeSouza, K.W. Michael Siu & Imogen R. Coe. (2010) Characterization of mammalian equilibrative nucleoside transporters (ENTs) by mass spectrometry. Protein Expression and Purification 73:1, pages 1-9.
Crossref
Morris J. Robins, Yunshan Peng, Vijaya L. Damaraju, Delores Mowles, Geraldine Barron, Tracey Tackaberry, James D. Young & Carol E. Cass. (2010) Improved Syntheses of 5′- S -(2-Aminoethyl)-6- N -(4-nitrobenzyl)-5′-thioadenosine (SAENTA), Analogues, and Fluorescent Probe Conjugates: Analysis of Cell-Surface Human Equilibrative Nucleoside Transporter 1 (hENT1) Levels for Prediction of the Antitumor Efficacy of Gemcitabine . Journal of Medicinal Chemistry 53:16, pages 6040-6053.
Crossref
David Knight, Philip J. Harvey, Konstantin G. Iliadi, Markus K. Klose, Natalia Iliadi, Eva Dolezelova, Milton P. Charlton, Michal Zurovec & Gabrielle L. Boulianne. (2010) Equilibrative Nucleoside Transporter 2 Regulates Associative Learning and Synaptic Function in Drosophila . The Journal of Neuroscience 30:14, pages 5047-5057.
Crossref
Dominique Deville-Bonne, Chahrazade El Amri, Philippe Meyer, Yuxing Chen, Luigi A. Agrofoglio & Joël Janin. (2010) Human and viral nucleoside/nucleotide kinases involved in antiviral drug activation: Structural and catalytic properties. Antiviral Research 86:1, pages 101-120.
Crossref
Jennifer B. RoseZlatina NaydenovaAndrew BangMegumi EguchiGary SweeneyDoo-Sup Choi, James R. Hammond & Imogen R. Coe. (2010) Equilibrative nucleoside transporter 1 plays an essential role in cardioprotection. American Journal of Physiology-Heart and Circulatory Physiology 298:3, pages H771-H777.
Crossref
Curtis D. Klaassen & Lauren M. Aleksunes. (2010) Xenobiotic, Bile Acid, and Cholesterol Transporters: Function and Regulation. Pharmacological Reviews 62:1, pages 1-96.
Crossref
Neil V. Morgan, Mark R. Morris, Hakan Cangul, Diane Gleeson, Anna Straatman-Iwanowska, Nicholas Davies, Stephen Keenan, Shanaz Pasha, Fatimah Rahman, Dean Gentle, Maaike P. G. Vreeswijk, Peter Devilee, Margaret A. Knowles, Serdar Ceylaner, Richard C. Trembath, Carlos Dalence, Erol Kismet, Vedat Köseoğlu, Hans-Christoph Rossbach, Paul Gissen, David Tannahill & Eamonn R. Maher. (2010) Mutations in SLC29A3, Encoding an Equilibrative Nucleoside Transporter ENT3, Cause a Familial Histiocytosis Syndrome (Faisalabad Histiocytosis) and Familial Rosai-Dorfman Disease. PLoS Genetics 6:2, pages e1000833.
Crossref
Cassandra S. Arendt & Buddy Ullman. (2010) Role of Transmembrane Domain 4 in Ligand Permeation by Crithidia fasciculata Equilibrative Nucleoside Transporter 2 (CfNT2). Journal of Biological Chemistry 285:9, pages 6024-6035.
Crossref
Robert J. Paproski, James D. Young & Carol E. Cass. (2010) Predicting gemcitabine transport and toxicity in human pancreatic cancer cell lines with the positron emission tomography tracer 3′-deoxy-3′-fluorothymidine. Biochemical Pharmacology 79:4, pages 587-595.
Crossref
Jean-Pierre Gillet & Michael M. Gottesman. 2010. Multi-Drug Resistance in Cancer. Multi-Drug Resistance in Cancer 47 76 .
Boris D. Zlatopolskiy, Agnieszka Morgenroth, Falk H.-G. Kunkel, Elizaveta A. Urusova, Cornelia Dinger, Thomas Kull, Christian Lepping & Sven N. Reske. (2009) Synthesis and Biologic Study of IV-14, a New Ribonucleoside Radiotracer for Tumor Visualization. Journal of Nuclear Medicine 50:11, pages 1895-1903.
Crossref
Audrey J. Robinson-White, Ioannis Bossis, Hui-Pin Hsiao, Maria Nesterova, Wolfgang W. Leitner & Constantine A. Stratakis. (2009) 8-Cl-Adenosine Inhibits Proliferation and Causes Apoptosis in B-Lymphocytes via Protein Kinase A-Dependent and Independent Effects: Implications for Treatment of Carney Complex-Associated Tumors. The Journal of Clinical Endocrinology & Metabolism 94:10, pages 4061-4069.
Crossref
Boris D. Zlatopolskiy, Agnieszka Morgenroth, Elizaveta A. Urusova, Cornelia Dinger, Thomas Kull, Manuela Pape, Gerhard Glatting & Sven N. Reske. (2009) Towards to hENT1-nucleoside transporter selective imaging agents. Synthesis and in vitro evaluation of the radiolabeled SAENTA analogues. Bioorganic & Medicinal Chemistry Letters 19:17, pages 5151-5154.
Crossref
Melissa D. Slugoski, Amy M.L. Ng, Sylvia Y.M. Yao, Colin C. Lin, Ras Mulinta, Carol E. Cass, Stephen A. Baldwin & James D. Young. (2009) Substituted Cysteine Accessibility Method Analysis of Human Concentrative Nucleoside Transporter hCNT3 Reveals a Novel Discontinuous Region of Functional Importance within the CNT Family Motif (G/A)XKX3NEFVA(Y/M/F). Journal of Biological Chemistry 284:25, pages 17281-17292.
Crossref
Melissa D. Slugoski, Kyla M. Smith, Amy M.L. Ng, Sylvia Y.M. Yao, Edward Karpinski, Carol E. Cass, Stephen A. Baldwin & James D. Young. (2009) Conserved Glutamate Residues Glu-343 and Glu-519 Provide Mechanistic Insights into Cation/Nucleoside Cotransport by Human Concentrative Nucleoside Transporter hCNT3. Journal of Biological Chemistry 284:25, pages 17266-17280.
Crossref
Kristie D. Ibarra & Julie K. Pfeiffer. (2009) Reduced Ribavirin Antiviral Efficacy via Nucleoside Transporter-Mediated Drug Resistance. Journal of Virology 83:9, pages 4538-4547.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.