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Xenobiotica
the fate of foreign compounds in biological systems
Volume 47, 2017 - Issue 4
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Topics in Xenobiochemistry

Clinical pharmacokinetics of panobinostat, a novel histone deacetylase (HDAC) inhibitor: review and perspectives

Pages 354-368 | Received 03 Apr 2016, Accepted 26 Apr 2016, Published online: 25 May 2016

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Yi Wu, Bo Zhang, Xiaowu Dong, Shenglin Ma & Shengquan Hu. (2022) Discovery of Novel Small Molecule HDAC1, 2, 3 Inhibitors -- Combined Receptor-Based and Ligand-Based Virtual Screening Strategy. Letters in Drug Design & Discovery 19:7, pages 627-636.
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Evangelos Eleutherakis-Papaiakovou, Nikolaos Kanellias, Efstathios Kastritis, Maria Gavriatopoulou, Evangelos Terpos & Meletios Athanasios Dimopoulos. (2020) Efficacy of Panobinostat for the Treatment of Multiple Myeloma. Journal of Oncology 2020, pages 1-11.
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Fang-I Huang, Yi-Wen Wu, Ting-Yi Sung, Jing-Ping Liou, Mei-Hsiang Lin, Shiow-Lin Pan & Chia-Ron Yang. (2019) MPT0G413, A Novel HDAC6-Selective Inhibitor, and Bortezomib Synergistically Exert Anti-tumor Activity in Multiple Myeloma Cells. Frontiers in Oncology 9.
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B Rösler, X Wang, S T Keating, L A B Joosten, M G Netea & F L van de Veerdonk. (2018) HDAC inhibitors modulate innate immune responses to micro-organisms relevant to chronic mucocutaneous candidiasis. Clinical and Experimental Immunology 194:2, pages 205-219.
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Hsueh-Yun Lee, Kunal Nepali, Fang-I Huang, Chih-Yi Chang, Mei-Jung Lai, Yu-Hsuan Li, Hsiang-Ling Huang, Chia-Ron Yang & Jing-Ping Liou. (2018) ( N -Hydroxycarbonylbenylamino)quinolines as Selective Histone Deacetylase 6 Inhibitors Suppress Growth of Multiple Myeloma in Vitro and in Vivo . Journal of Medicinal Chemistry 61:3, pages 905-917.
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Kalpesh Kumar Giri, P. S. Suresh, Syed Mohd Saim, Mohd Zainuddin, Ravi Kanth Bhamidipati, Purushottam Dewang, Mahanandeesha S. Hallur, Sridharan Rajagopal, Sriram Rajagopal & Ramesh Mullangi. (2017) Validation of an LC–MS/MS method for simultaneous detection of four HDAC inhibitors – belinostat, panobinostat, rocilinostat and vorinostat in mouse plasma and its application to a mouse pharmacokinetic study. Biomedical Chromatography 31:7.
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Badar ul Islam & Shams Tabrez. (2017) Management of Alzheimer’s disease—An insight of the enzymatic and other novel potential targets. International Journal of Biological Macromolecules 97, pages 700-709.
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Vanita Chopra, Luisa Quinti, Prarthana Khanna, Paolo Paganetti, Rainer Kuhn, Anne B. Young, Aleksey G. Kazantsev & Steven Hersch. (2016) LBH589, A Hydroxamic Acid-Derived HDAC Inhibitor, is Neuroprotective in Mouse Models of Huntington’s Disease. Journal of Huntington's Disease 5:4, pages 347-355.
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