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Xenobiotica
the fate of foreign compounds in biological systems
Volume 47, 2017 - Issue 9
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Molecular Toxicology

Polychlorinated biphenyls disrupt hepatic epidermal growth factor receptor signaling

Josiah E. HardestyDepartment of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY, USA,
,
Banrida WahlangUniversity of Kentucky Superfund Research Center, University of Kentucky, Lexington, KY, USA,
,
K. Cameron FalknerDepartment of Medicine, Division of Gastroenterology, Hepatology and Nutrition, and
,
Heather B. ClairDepartment of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY, USA,
,
Barbara J. ClarkDepartment of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY, USA,
,
Brian P. CeresaDepartment of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, KY, USA,
,
Russell A. ProughDepartment of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY, USA,
&
Matthew C. CaveDepartment of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY, USA, ;Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, and ;Department of Pharmacology and Toxicology, University of Louisville School of Medicine, Louisville, KY, USA, ;The Robley Rex Veterans Affairs Medical Center, Louisville, KY, USA, and ;The Kentucky One Health Jewish Hospital Liver Transplant Program, Louisville, KY, USACorrespondence[email protected]
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Pages 807-820 | Received 10 May 2016, Accepted 24 Jul 2016, Published online: 21 Jun 2017

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Hongxue Shi, Josiah E. Hardesty, Jian Jin, Kimberly Z. Head, K. Cameron Falkner, Matthew C. Cave & Russell Allen Prough. (2019) Concentration dependence of human and mouse aryl hydrocarbon receptor responsiveness to polychlorinated biphenyl exposures: Implications for aroclor mixtures. Xenobiotica 49:12, pages 1414-1422.
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Articles from other publishers (21)

Anita A. Waye, Elvis Ticiani & Almudena Veiga-Lopez. (2024) Chemical mixture that targets the epidermal growth factor pathway impairs human trophoblast cell functions. Toxicology and Applied Pharmacology 483, pages 116804.
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Chi Yen Tseng, Christine M. Custer, Thomas W. Custer, Paul M. Dummer, Natalie Karouna-Renier & Cole W. Matson. (2023) Multi-omics responses in tree swallow (Tachycineta bicolor) nestlings from the Maumee Area of Concern, Maumee River, Ohio. Science of The Total Environment 856, pages 159130.
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Belinda J. Petri, Kellianne M. Piell, Banrida Wahlang, Kimberly Z. Head, Kalina Andreeva, Eric C. Rouchka, Matthew C. Cave & Carolyn M. Klinge. (2023) Polychlorinated biphenyls alter hepatic m6A mRNA methylation in a mouse model of environmental liver disease. Environmental Research 216, pages 114686.
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Belinda J. Petri, Kellianne M. Piell, Banrida Wahlang, Kimberly Z. Head, Kalina Andreeva, Eric C. Rouchka, Jianmin Pan, Shesh N. Rai, Matthew C. Cave & Carolyn M. Klinge. (2022) Multiomics analysis of the impact of polychlorinated biphenyls on environmental liver disease in a mouse model. Environmental Toxicology and Pharmacology 94, pages 103928.
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Maegan E. Boutot, Brian W. Whitcomb, Nadia Abdelouahab, Andrea A. Baccarelli, Amélie Boivin, Artuela Caku, Virginie Gillet, Guillaume Martinez, Jean-Charles Pasquier, Jiping Zhu, Larissa Takser, Lindsay St-Cyr & Alexander Suvorov. (2021) In Utero Exposure to Persistent Organic Pollutants and Childhood Lipid Levels. Metabolites 11:10, pages 657.
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Josiah E. Hardesty, Banrida Wahlang, Russell A. Prough, Kim Z. Head, Daniel Wilkey, Michael Merchant, Hongxue Shi, Jian Jin & Matthew C. Cave. (2021) Effect of Epidermal Growth Factor Treatment and Polychlorinated Biphenyl Exposure in a Dietary-Exposure Mouse Model of Steatohepatitis. Environmental Health Perspectives 129:3.
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Elvis Ticiani, Jeremy Gingrich, Yong Pu, Mathew Vettathu, Jacquelyn Davis, Denny Martin, Margaret G. Petroff & Almudena Veiga-Lopez. (2021) Bisphenol S and Epidermal Growth Factor Receptor Signaling in Human Placental Cytotrophoblasts. Environmental Health Perspectives 129:2.
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Masahiko Negishi, Kaoru Kobayashi, Tsutomu Sakuma & Tatsuya Sueyoshi. (2020) Nuclear receptor phosphorylation in xenobiotic signal transduction. Journal of Biological Chemistry 295:45, pages 15210-15225.
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Jenni Küblbeck, Jonna Niskanen & Paavo Honkakoski. (2020) Metabolism-Disrupting Chemicals and the Constitutive Androstane Receptor CAR. Cells 9:10, pages 2306.
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Jian Jin, Banrida Wahlang, Hongxue Shi, Josiah E. Hardesty, K. Cameron Falkner, Kimberly Z. Head, Sudhir Srivastava, Michael L. Merchant, Shesh N. Rai, Matthew C. Cave & Russell A. Prough. (2020) Dioxin-like and non-dioxin-like PCBs differentially regulate the hepatic proteome and modify diet-induced nonalcoholic fatty liver disease severity. Medicinal Chemistry Research 29:7, pages 1247-1263.
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Igor O. Shmarakov, Yun Jee Lee, Hongfeng Jiang & William S. Blaner. (2019) Constitutive androstane receptor mediates PCB-induced disruption of retinoid homeostasis. Toxicology and Applied Pharmacology 381, pages 114731.
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Banrida Wahlang, Jian Jin, Juliane I. Beier, Josiah E. Hardesty, Erica F. Daly, Regina D. Schnegelberger, K. Cameron Falkner, Russell A. Prough, Irina A Kirpich & Matthew C. Cave. (2019) Mechanisms of Environmental Contributions to Fatty Liver Disease. Current Environmental Health Reports 6:3, pages 80-94.
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Banrida Wahlang, Jian Jin, Josiah E. Hardesty, Kimberly Z. Head, Hongxue Shi, K. Cameron Falkner, Russell A. Prough, Carolyn M. Klinge & Matthew C. Cave. (2019) Identifying sex differences arising from polychlorinated biphenyl exposures in toxicant-associated liver disease. Food and Chemical Toxicology 129, pages 64-76.
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Josiah E. Hardesty, Banrida Wahlang, K. Cameron Falkner, Hongxue Shi, Jian Jin, Yun Zhou, Daniel W. Wilkey, Michael L. Merchant, Corey T. Watson, Wenke Feng, Andrew J. Morris, Bernhard Hennig, Russell A. Prough & Matthew C. Cave. (2019) Proteomic Analysis Reveals Novel Mechanisms by Which Polychlorinated Biphenyls Compromise the Liver Promoting Diet-Induced Steatohepatitis. Journal of Proteome Research 18:4, pages 1582-1594.
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Banrida Wahlang, Josiah E. Hardesty, Jian Jin, K. Cameron Falkner & Matthew C. Cave. (2019) Polychlorinated biphenyls and nonalcoholic fatty liver disease. Current Opinion in Toxicology 14, pages 21-28.
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Hongxue Shi, Jian Jan, Josiah E. Hardesty, K. Cameron Falkner, Russell A. Prough, Appakalai N. Balamurugan, Sri Prakash Mokshagundam, Suresh T. Chari & Matthew C. Cave. (2019) Polychlorinated biphenyl exposures differentially regulate hepatic metabolism and pancreatic function: Implications for nonalcoholic steatohepatitis and diabetes. Toxicology and Applied Pharmacology 363, pages 22-33.
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Fengming Chen, Denise M. Coslo, Tao Chen, Limin Zhang, Yuan Tian, Philip B Smith, Andrew D. Patterson & Curtis J Omiecinski. (2018) Metabolomic approaches reveal the role of CAR in energy metabolism. Journal of Proteome Research.
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Alejandro Carazo, Jan Dusek, Ondrej Holas, Josef Skoda, Lucie Hyrsova, Tomas Smutny, Tomas Soukup, Martin Dosedel & Petr Pávek. (2018) Teriflunomide Is an Indirect Human Constitutive Androstane Receptor (CAR) Activator Interacting With Epidermal Growth Factor (EGF) Signaling. Frontiers in Pharmacology 9.
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Kimberly P. Keil, Galen W. Miller, Hao Chen, Sunjay Sethi, Martin R. Schmuck, Kiran Dhakal, Ji Won Kim & Pamela J. Lein. (2018) PCB 95 promotes dendritic growth in primary rat hippocampal neurons via mTOR-dependent mechanisms. Archives of Toxicology 92:10, pages 3163-3173.
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Prachi Gupta, Brendan L. Thompson, Banrida Wahlang, Carolyn T. Jordan, J. Zach Hilt, Bernhard Hennig & Thomas Dziubla. (2017) The environmental pollutant, polychlorinated biphenyls, and cardiovascular disease: a potential target for antioxidant nanotherapeutics. Drug Delivery and Translational Research 8:3, pages 740-759.
Crossref
Chi Yen Tseng, Christine M. Custer, Thomas W. Custer, Paul M. Dummer, Natalie Karouna‐Renier & Cole W. Matson. (2022) Multi-Omics Responses in Tree Swallow (Tachycineta Bicolor) Nestlings from the Maumee Area of Concern, Maumee River, Ohio. SSRN Electronic Journal.
Crossref

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