Citations (16)
Keep up to date with the latest research on this topic with citation updates for this article.
Read on this site (1)
Shin-ichiro Ogawa, Makiko Shimizu & Hiroshi Yamazaki. (2020) Plasma concentrations of pemafibrate with co-administered drugs predicted by physiologically based pharmacokinetic modeling in virtual populations with renal/hepatic impairment. Xenobiotica 50:9, pages 1023-1031.
Read now
Read now
Articles from other publishers (15)
Makiko Shimizu, Shotaro Uehara, Katsuhiro Ohyama, Haruka Nishimura, Yoichi Tanaka, Yoshiro Saito, Hiroshi Suemizu, Sayaka Yoshida & Hiroshi Yamazaki. (2024)
Pharmacokinetic Models Scaled Up from Humanized Liver Mouse Data Can Account for Drug Monitoring Results of Atomoxetine and Its 4-Hydroxylated and
N
-Demethylated Metabolites in Pediatric Patients Genotyped for Cytochrome
P450 2D6
. Drug Metabolism and Disposition 52:1, pages 35-43.
Crossref
Crossref
Shotaro Uehara, Makiko Shimizu, Hiroshi Suemizu & Hiroshi Yamazaki. (2023) Roles of human cytochrome P450 3A4/5 in dexamethasone 6β-hydroxylation mediated by liver microsomes and humanized liver in chimeric mice metabolically suppressed with azamulin. Drug Metabolism and Pharmacokinetics 50, pages 100504.
Crossref
Crossref
Alessia Paradiso, Marina Volpi, Chiara Rinoldi, Nehar Celikkin, Nicola Contessi Negrini, Muge Bilgen, Giorgio Dallera, Filippo Pierini, Marco Costantini, Wojciech Święszkowski & Silvia Farè. (2023)
In vitro
functional models for human liver diseases and drug screening: beyond animal testing
. Biomaterials Science 11:9, pages 2988-3015.
Crossref
Crossref
Hyunki Cho, Young Jun Kim, Jung-Woo Chae, Markus R. Meyer, Sang Kyum Kim & Chang Seon Ryu. (2023) In vitro metabolic characterization of the SARS-CoV-2 papain-like protease inhibitors GRL0617 and HY-17542. Frontiers in Pharmacology 14.
Crossref
Crossref
Hiroshi Yamazaki & Makiko Shimizu. (2023) Species Specificity and Selection of Models for Drug Oxidations Mediated by Polymorphic Human Enzymes. Drug Metabolism and Disposition 51:1, pages 123-129.
Crossref
Crossref
Melissa L. Sykes, Emily K. Kennedy, Kevin D. Read, Marcel Kaiser & Vicky M. Avery. (2022) Temporal and Wash-Out Studies Identify Medicines for Malaria Venture Pathogen Box Compounds with Fast-Acting Activity against Both Trypanosoma cruzi and Trypanosoma brucei. Microorganisms 10:7, pages 1287.
Crossref
Crossref
Daigo Asano, Syoya Hamaue, Hamim Zahir, Hideyuki Shiozawa, Yumi Nishiya, Takako Kimura, Miho Kazui, Naotoshi Yamamura, Marie Ikeguchi, Takahiro Shibayama, Shin-ichi Inoue, Tsuyoshi Shinozuka, Toshiyuki Watanabe, Chizuko Yahara, Nobuaki Watanabe & Kouichi Yoshinari. (2022)
CYP2C8-Mediated Formation of a Human Disproportionate Metabolite of the Selective Na
V
1.7 Inhibitor DS-1971a, a Mixed Cytochrome P450 and Aldehyde Oxidase Substrate
. Drug Metabolism and Disposition 50:3, pages 235-242.
Crossref
Crossref
L. Ward, Philip Butler & Robert J. Riley. 2022. The ADME Encyclopedia. The ADME Encyclopedia
631
641
.
Heather Zhang, Ying C. Ou, Dan Su, Fan Wang, Lai Wang, Srikumar Sahasranaman & Zhiyu Tang. (2021) In vitro investigations into the roles of CYP450 enzymes and drug transporters in the drug interactions of zanubrutinib, a covalent Bruton's tyrosine kinase inhibitor. Pharmacology Research & Perspectives 9:6.
Crossref
Crossref
Cathy Lester, Nicola J. Hewitt, Ursula Müller-Vieira, Manuela Mayer, Corie Ellison, Hélène Duplan, Camille Genies, Carine Jacques-Jamin, Eric Fabian, Ian Sorrell, Daniela Lange, Andreas Schepky & Sébastien Grégoire. (2021) Metabolism and plasma protein binding of 16 straight- and branched-chain parabens in in vitro liver and skin models. Toxicology in Vitro 72, pages 105051.
Crossref
Crossref
Rakshit S. Tanna, Dan-Dan Tian, Nadja B. Cech, Nicholas H. Oberlies, Allan E. Rettie, Kenneth E. Thummel & Mary F. Paine. (2021) Refined Prediction of Pharmacokinetic Kratom-Drug Interactions: Time-Dependent Inhibition Considerations. Journal of Pharmacology and Experimental Therapeutics 376:1, pages 64-73.
Crossref
Crossref
Christof Dücker & Jürgen Brockmöller. (2021) How precise is quantitative prediction of pharmacokinetic effects due to drug-drug interactions and genotype from in vitro data? A comprehensive analysis on the example CYP2D6 and CYP2C19 substrates. Pharmacology & Therapeutics 217, pages 107629.
Crossref
Crossref
L. Ward, P. Butler & R. Riley. 2021. The ADME Encyclopedia. The ADME Encyclopedia
1
11
.
Jeffry Adiwidjaja, Alan V. Boddy & Andrew J. McLachlan. (2020)
Potential for pharmacokinetic interactions between
Schisandra sphenanthera
and bosutinib, but not imatinib: in vitro metabolism study combined with a physiologically‐based pharmacokinetic modelling approach
. British Journal of Clinical Pharmacology 86:10, pages 2080-2094.
Crossref
Crossref
Hugues Chanteux, Maria Rosa, Claude Delatour, Johan Nicolaï, Eric Gillent, Sylvie Dell’Aiera & Anna-Lena Ungell. (2020) Application of Azamulin to Determine the Contribution of CYP3A4/5 to Drug Metabolic Clearance Using Human Hepatocytes. Drug Metabolism and Disposition 48:9, pages 778-787.
Crossref
Crossref