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Xenobiotica
the fate of foreign compounds in biological systems
Volume 49, 2019 - Issue 7
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General Xenobiochemistry

The impact of azole antifungal drugs on imatinib metabolism in human liver microsomes

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Pages 753-761 | Received 19 Mar 2018, Accepted 03 May 2018, Published online: 25 Mar 2019

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Anna Sofie Buhl Rasmussen, Christen Lykkegaard Andersen, Allan Weimann, Tianwu Yang, Camille Tron, Virginie Gandemer, Kim Dalhoff, Cecilie Utke Rank & Kjeld Schmiegelow. (2024) Therapeutic drug monitoring of imatinib – how far are we in the leukemia setting?. Expert Review of Clinical Pharmacology 17:3, pages 225-234.
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Josefine Schulz, Franziska Kluwe, Gerd Mikus, Robin Michelet & Charlotte Kloft. (2019) Novel insights into the complex pharmacokinetics of voriconazole: a review of its metabolism. Drug Metabolism Reviews 51:3, pages 247-265.
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Dan Lou, Xiao Cui, Su-Su Bao, Wei Sun, Wen-He Pan, Meng-Chun Chen, Yao-Yao Dong, Guo-Xin Hu, Rui-Jie Chen & Zhe Wang. (2019) Effects of ketoconazole, voriconazole, and itraconazole on the pharmacokinetics of apatinib in rats. Drug Development and Industrial Pharmacy 45:4, pages 689-693.
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Qianmeng Lin, Saili Xie, Xiangjun Qiu, Jingjing Chen & Ren-Ai Xu. (2019) Drug–drug interaction study of imatinib and voriconazole in vitro and in vivo. Infection and Drug Resistance 12, pages 1021-1027.
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Yutao Lou, Feifeng Song, Mengting Cheng, Ying Hu, Yitao Chai, Qing Hu, Qiyue Wang, Hongying Zhou, Meihua Bao, Jinping Gu & Yiwen Zhang. (2023) Effects of the CYP3A inhibitors, voriconazole, itraconazole, and fluconazole on the pharmacokinetics of osimertinib in rats. PeerJ 11, pages e15844.
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Josefine Schulz, Antonia Thomas, Ayatallah Saleh, Gerd Mikus, Charlotte Kloft & Robin Michelet. (2022) Towards the Elucidation of the Pharmacokinetics of Voriconazole: A Quantitative Characterization of Its Metabolism. Pharmaceutics 14:3, pages 477.
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Brit Silja Rohr, Kathrin Isabelle Foerster, Antje Blank, Jürgen Burhenne, Mazyar Mahmoudi, Walter Emil Haefeli & Gerd Mikus. (2021) Perpetrator Characteristics of Azole Antifungal Drugs on Three Oral Factor Xa Inhibitors Administered as a Microdosed Cocktail. Clinical Pharmacokinetics 61:1, pages 97-109.
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Andrzej Czyrski, Matylda Resztak, Paweł Świderski, Jan Brylak & Franciszek K. Główka. (2021) The Overview on the Pharmacokinetic and Pharmacodynamic Interactions of Triazoles. Pharmaceutics 13:11, pages 1961.
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Xingxian Luo, Xuecai Xue, Taifeng Li, Ying Zhang, Lin Huang & Gang Cheng. (2020) Differential Impacts of Azole Antifungal Drugs on the Pharmacokinetic Profiles of Dasatinib in Rats by LC-MS-MS. Current Drug Metabolism 21:13, pages 1022-1030.
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Ren-ai Xu, Qianmeng Lin, Xiangjun Qiu, Jingjing Chen, Yuanyuan Shao, Guoxin Hu & Guanyang Lin. (2019) UPLC-MS/MS method for the simultaneous determination of imatinib, voriconazole and their metabolites concentrations in rat plasma. Journal of Pharmaceutical and Biomedical Analysis 166, pages 6-12.
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