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Xenobiotica
the fate of foreign compounds in biological systems
Volume 52, 2022 - Issue 1
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Animal Pharmacokinetics and Metabolism

Absorption, distribution, metabolism, and excretion of [14C]TPN729 after oral administration to rats

Huan Chenga School of Pharmaceutical Sciences, Shandong University of Traditional Chinese Medicine, Jinan, China;b Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, ChinaView further author information
,
Jinghua Yub Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, ChinaView further author information
,
Chen Yangb Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, ChinaView further author information
,
Ning Zhangb Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, ChinaView further author information
,
Zhen Fanc Henan Topfond Pharma Co., Ltd, Zhumadian, ChinaView further author information
,
Xiaojuan Zhangc Henan Topfond Pharma Co., Ltd, Zhumadian, ChinaView further author information
,
Junchen Wangc Henan Topfond Pharma Co., Ltd, Zhumadian, ChinaView further author information
,
Zhen Wangb Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, ChinaView further author information
,
Da-fang Zhongb Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, ChinaView further author information
,
Ji-Xiang Hea School of Pharmaceutical Sciences, Shandong University of Traditional Chinese Medicine, Jinan, ChinaCorrespondence[email protected]
View further author information
,
Shu Yanb Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, ChinaCorrespondence[email protected]
View further author information
&
Xingxing Diaob Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, ChinaCorrespondence[email protected]
View further author information
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Pages 79-90 | Received 03 Nov 2021, Accepted 13 Jan 2022, Published online: 27 Jan 2022

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Xinyu Ge, Sheng Ma, Shu Yan, Yali Wu, Chong Chen, Chongzhuang Tang, Yan Zhan, Yi-cong Bian, Kai Shen, Sheng Feng, Xuehu Gao, Dafang Zhong, Hua Zhang, Li-yan Miao & Xing-xing Diao. (2023) Mass balance study of [14C]SHR0302, a selective and potent JAK1 inhibitor in humans. Xenobiotica 53:2, pages 69-83.
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Articles from other publishers (3)

Xinyue Zhang, Donghui Liu, Ming Lu, Yali Yuan, Chen Yang, Ying Yang, Jin Xiu, Pingsheng Hu, Yuandong Zheng & Xingxing Diao. (2024) Absorption, distribution, metabolism and excretion of linaprazan glurate in rats. Journal of Pharmaceutical and Biomedical Analysis 242, pages 116012.
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Xinyu Ge, Yuandong Zheng, Yifei He, Chong Chen, Chen Yang, Saiwei Lu, Zhenyu Xuan, Dafang Zhong & Xingxing Diao. (2023) Pharmacokinetics, Mass Balance, Tissue Distribution, and Metabolism of [3H]Catalpol in Rats: the Main Bioactive Component of Rehmannia glutinosa for the Treatment of Ischemic Stroke. Current Drug Metabolism 24:6, pages 448-457.
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Xin-mei Li, Yuan-dong Zheng, Yi-fan Zhang, Xia-juan Huan, Chen Yang, Meng-ling Liu, Xiao-kun Shen, Chun-hao Yang & Xing-xing Diao. (2022) Absorption, distribution, metabolism, and excretion of [14C]Mefuparib (CVL218), a novel PARP1/2 inhibitor, in rats. Cancer Chemotherapy and Pharmacology 90:6, pages 499-510.
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