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Xenobiotica
the fate of foreign compounds in biological systems
Volume 52, 2022 - Issue 1
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Animal Pharmacokinetics and Metabolism

Pharmacokinetics and metabolism of mirogabalin, a novel α2δ ligand, in rats and monkeys

Naotoshi YamamuraDrug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, JapanCorrespondence[email protected]
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,
Minoru UchiyamaDrug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, JapanView further author information
,
Makoto TakahashiDrug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, JapanView further author information
,
Tomoyo HondaDrug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, JapanView further author information
&
Yumi NishiyaDrug Metabolism & Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, JapanView further author information
Pages 54-64 | Received 07 Jan 2022, Accepted 01 Mar 2022, Published online: 10 Mar 2022

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Naotoshi Yamamura, Tomoki Imaoka, Misa Hoshi, Makiko Yamada & Ken-ichi Itokawa. (2023) Renal tubular transporter-mediated interactions between mirogabalin and cimetidine in rats. Xenobiotica 53:2, pages 114-122.
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Naotoshi Yamamura, Tsuyoshi Mikkaichi, Ken-ichi Itokawa, Misa Hoshi, Katja Damme, Stefanie Geigner & Christine Baumhauer. (2022) Mirogabalin, a novel α2δ ligand, is not a substrate of LAT1, but of PEPT1, PEPT2, OAT1, OAT3, OCT2, MATE1 and MATE2-K. Xenobiotica 52:9-11, pages 997-1009.
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