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Original

Modafinil and Cocaine Interactions

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Pages 577-587 | Published online: 07 Jul 2009

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Read on this site (6)

Dinesh Sangroula, Fatima Motiwala, Bivek Wagle, Vivek C. Shah, Katsuhiko Hagi & Steven Lippmann. (2017) Modafinil Treatment of Cocaine Dependence: A Systematic Review and Meta-Analysis. Substance Use & Misuse 52:10, pages 1292-1306.
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Jee Hyun Kim & Andrew J Lawrence. (2014) Drugs currently in Phase II clinical trials for cocaine addiction. Expert Opinion on Investigational Drugs 23:8, pages 1105-1122.
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Gabriel C Quintero. (2013) Role of nucleus accumbens glutamatergic plasticity in drug addiction. Neuropsychiatric Disease and Treatment 9, pages 1499-1512.
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Christopher D Verrico, Colin N Haile, Thomas F Newton, Thomas R Kosten & Richard De La Garza. (2013) Pharmacotherapeutics for substance-use disorders: a focus on dopaminergic medications. Expert Opinion on Investigational Drugs 22:12, pages 1549-1568.
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Noèlia Fernàndez-castillo, Bru Cormand, Carlos Roncero, Cristina Sánchez-Mora, Lara Grau-Lopez, Begoña Gonzalvo, Laia Miquel, Roser Corominas, Josep Antoni Ramos-Quiroga, Miquel Casas & Marta Ribasés. (2012) Candidate pathway association study in cocaine dependence: The control of neurotransmitter release. The World Journal of Biological Psychiatry 13:2, pages 126-134.
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James Shearer. (2008) The principles of agonist pharmacotherapy for psychostimulant dependence. Drug and Alcohol Review 27:3, pages 301-308.
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Quang Ngo & David T. Plante. (2022) An Update on the Misuse and Abuse Potential of Pharmacological Treatments for Central Disorders of Hypersomnolence. Current Sleep Medicine Reports 8:4, pages 147-159.
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Samantha N Scott, Raul Garcia, Gregory L Powell, Sophia M Doyle, Brielle Ruscitti, Tien Le, Aracely Esquer, Kevin M Blattner, Benjamin E Blass & Janet L Neisewander. (2021) 5-HT 1B receptor agonist attenuates cocaine self-administration after protracted abstinence and relapse in rats . Journal of Psychopharmacology 35:10, pages 1216-1225.
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Laura Brandt, Thomas Chao, Sandra D. Comer & Frances R. Levin. (2020) Pharmacotherapeutic strategies for treating cocaine use disorder—what do we have to offer?. Addiction 116:4, pages 694-710.
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Margaret Haney, Eric Rubin, Rebecca K. Denson & Richard W. Foltin. (2021) Modafinil reduces smoked cocaine self-administration in humans: effects vary as a function of cocaine ‘priming’ and cost. Drug and Alcohol Dependence 221, pages 108554.
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Adriano Zager. (2020) Modulating the immune response with the wake-promoting drug modafinil: A potential therapeutic approach for inflammatory disorders. Brain, Behavior, and Immunity 88, pages 878-886.
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Kyle M. Kampman. (2019) The treatment of cocaine use disorder. Science Advances 5:10.
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Joy M. Schmitz, Angela L. Stotts, Anka A. Vujanovic, Michael F. Weaver, Jin H. Yoon, Jessica Vincent & Charles E. Green. (2018) A sequential multiple assignment randomized trial for cocaine cessation and relapse prevention: Tailoring treatment to the individual. Contemporary Clinical Trials 65, pages 109-115.
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Hai-Ying Zhang, Guo-Hua Bi, Hong-Ju Yang, Yi He, Gilbert Xue, Jiajing Cao, Gianluigi Tanda, Eliot L Gardner, Amy Hauck Newman & Zheng-Xiong Xi. (2017) The Novel Modafinil Analog, JJC8-016, as a Potential Cocaine Abuse Pharmacotherapeutic. Neuropsychopharmacology 42:9, pages 1871-1883.
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Geraldine Dowling, Pierce V. Kavanagh, Brian Talbot, John O’Brien, Gary Hessman, Gavin McLaughlin, Brendan Twamley & Simon D. Brandt. (2017) Outsmarted by nootropics? An investigation into the thermal degradation of modafinil, modafinic acid, adrafinil, CRL-40,940 and CRL-40,941 in the GC injector: formation of 1,1,2,2-tetraphenylethane and its tetra fluoro analog. Drug Testing and Analysis 9:3, pages 518-528.
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Jianjing Cao, Rachel D. Slack, Oluyomi M. Bakare, Caitlin Burzynski, Rana Rais, Barbara S. Slusher, Theresa Kopajtic, Alessandro Bonifazi, Michael P. Ellenberger, Hideaki Yano, Yi He, Guo-Hua Bi, Zheng-Xiong Xi, Claus J. Loland & Amy Hauck Newman. (2016) Novel and High Affinity 2-[(Diphenylmethyl)sulfinyl]acetamide (Modafinil) Analogues as Atypical Dopamine Transporter Inhibitors. Journal of Medicinal Chemistry 59:23, pages 10676-10691.
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Ariadna Amador, Salvador Huitron-Resendiz, Amanda J. Roberts, Theodore M. Kamenecka, Laura A. Solt & Thomas P. Burris. (2016) Pharmacological Targeting the REV-ERBs in Sleep/Wake Regulation. PLOS ONE 11:9, pages e0162452.
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Laurence Lalanne, Pierre-Eric Lutz, Benoit Trojak, Jean-Philippe Lang, Brigitte L. Kieffer & Elisabeth Bacon. (2016) Medications between psychiatric and addictive disorders. Progress in Neuro-Psychopharmacology and Biological Psychiatry 65, pages 215-223.
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Amanda J. Quisenberry & Lisa E. Baker. (2015) Dopaminergic mediation of the discriminative stimulus functions of modafinil in rats. Psychopharmacology 232:24, pages 4411-4419.
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Kyle M. Kampman, Kevin G. Lynch, Helen M. Pettinati, Kelly Spratt, Michael R. Wierzbicki, Charles Dackis & Charles P. O’Brien. (2015) A double blind, placebo controlled trial of modafinil for the treatment of cocaine dependence without co-morbid alcohol dependence. Drug and Alcohol Dependence 155, pages 105-110.
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Xiao-Fei Wang, Guo-Hua Bi, Yi He, Hong-Ju Yang, Jun-Tao Gao, Oluyomi M Okunola-Bakare, Rachel D Slack, Eliot L Gardner, Zheng-Xiong Xi & Amy Hauck Newman. (2015) R-Modafinil Attenuates Nicotine-Taking and Nicotine-Seeking Behavior in Alcohol-Preferring Rats. Neuropsychopharmacology 40:7, pages 1762-1771.
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Christopher D. Verrico, Colin N. Haile, James J. Mahoney III, Daisy G.Y. Thompson-Lake, Thomas F. Newton & Richard De La Garza II. (2014) Treatment with modafinil and escitalopram, alone and in combination, on cocaine-induced effects: A randomized, double blind, placebo-controlled human laboratory study. Drug and Alcohol Dependence 141, pages 72-78.
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Joy M. Schmitz, Charles E. Green, Angela L. Stotts, Jan A. Lindsay, Nuvan S. Rathnayaka, John Grabowski & F. Gerard Moeller. (2014) A two-phased screening paradigm for evaluating candidate medications for cocaine cessation or relapse prevention: Modafinil, levodopa–carbidopa, naltrexone. Drug and Alcohol Dependence 136, pages 100-107.
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Maddalena Mereu, Antonello Bonci, Amy Hauck Newman & Gianluigi Tanda. (2013) The neurobiology of modafinil as an enhancer of cognitive performance and a potential treatment for substance use disorders. Psychopharmacology 229:3, pages 415-434.
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Amanda J. Quisenberry, Thomas Prisinzano & Lisa E. Baker. (2013) Combined effects of modafinil and d-amphetamine in male Sprague–Dawley rats trained to discriminate d-amphetamine. Pharmacology Biochemistry and Behavior 110, pages 208-215.
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Charles A. Dackis, Kyle M. Kampman, Kevin G. Lynch, Jennifer G. Plebani, Helen M. Pettinati, Thorne Sparkman & Charles P. O'Brien. (2012) A double-blind, placebo-controlled trial of modafinil for cocaine dependence. Journal of Substance Abuse Treatment 43:3, pages 303-312.
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Charles P. O'Brien. (2012) Modafinil-Cocaine Interactions: Clinical Implications. Biological Psychiatry 72:5, pages 346.
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Colin N. Haile, James J. MahoneyIIIIII, Thomas F. Newton & Richard De La GarzaIIII. (2012) Pharmacotherapeutics directed at deficiencies associated with cocaine dependence: Focus on dopamine, norepinephrine and glutamate. Pharmacology & Therapeutics 134:2, pages 260-277.
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Craig R RushWilliam W Stoops. (2012) Agonist replacement therapy for cocaine dependence: a translational review. Future Medicinal Chemistry 4:2, pages 245-265.
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Christine Yuodelis-Flores, Richard K. Ries & W. Murray Bennett. 2012. Handbook of Community Psychiatry. Handbook of Community Psychiatry 277 292 .
Kathleen T. Brady, Kevin M. Gray & Bryan K. Tolliver. (2011) Cognitive enhancers in the treatment of substance use disorders: Clinical evidence. Pharmacology Biochemistry and Behavior 99:2, pages 285-294.
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Dawn E. Sugarman, James Poling & Mehmet Sofuoglu. (2011) The safety of modafinil in combination with oral ∆9-tetrahydrocannabinol in humans. Pharmacology Biochemistry and Behavior 98:1, pages 94-100.
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Clara Pérez-Mañá, Xavier Castells, Xavier Vidal, Miguel Casas & Dolors Capellà. (2011) Efficacy of indirect dopamine agonists for psychostimulant dependence: A systematic review and meta-analysis of randomized controlled trials. Journal of Substance Abuse Treatment 40:2, pages 109-122.
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Pouya Tahsili-Fahadan, Gregory V Carr, Glenda C Harris & Gary Aston-Jones. (2010) Modafinil Blocks Reinstatement of Extinguished Opiate-Seeking in Rats: Mediation by a Glutamate Mechanism. Neuropsychopharmacology 35:11, pages 2203-2210.
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Kyle M. Kampman. (2010) What’s New in the Treatment of Cocaine Addiction?. Current Psychiatry Reports 12:5, pages 441-447.
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David V. Herin, Craig. R. Rush & John Grabowski. (2010) Agonist-like pharmacotherapy for stimulant dependence: preclinical, human laboratory, and clinical studies. Annals of the New York Academy of Sciences 1187:1, pages 76-100.
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Heath D. Schmidt & R. Christopher Pierce. (2010) Cocaine-induced neuroadaptations in glutamate transmission. Annals of the New York Academy of Sciences 1187:1, pages 35-75.
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Suzanne K. Vosburg, Carl L. Hart, Margaret Haney, Eric Rubin & Richard W. Foltin. (2010) Modafinil does not serve as a reinforcer in cocaine abusers. Drug and Alcohol Dependence 106:2-3, pages 233-236.
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