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Research Article

Lead-Induced Genotoxicity in Lymphocytes from Peripheral Blood Samples of Humans: In Vitro Studies

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Pages 111-124 | Published online: 09 Oct 2008

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Saeed Alshahrani, Pankaj Tripathi, Hassan A. Alhazmi, Syed Mamoon Hussain, Abdul Hakeem Siddiqui, Waquar Ahsan & Mohammad Al Bratty. (2021) Genotoxicity of yellow shammah (smokeless tobacco) in murine bone marrow cells in vivo. Drug and Chemical Toxicology 44:2, pages 124-129.
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Articles from other publishers (28)

Dengnan Yang. (2023) Lead toxicity. Highlights in Science, Engineering and Technology 40, pages 209-213.
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Sirirak Hemmaphan & Narisa K. Bordeerat. (2022) Genotoxic Effects of Lead and Their Impact on the Expression of DNA Repair Genes. International Journal of Environmental Research and Public Health 19:7, pages 4307.
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Yu Meng, Kan Wang, Tuanwei Wang, Yuting Tu, Shiyang Gong, Yunxia Zhang, Guanghui Zhang, William Au, David C. Christiani & Zhao-lin Xia. (2021) Early occupational exposure to lead on neutrophil-to-lymphocyte ratio and genotoxicity. Environment International 151, pages 106448.
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Andrea Čabarkapa, Dragana Dekanski, Lada Živković, Mirjana Milanović-Čabarkapa, Vladan Bajić, Dijana Topalović, Francesca Giampieri, Massimiliano Gasparrini, Maurizio Battino & Biljana Spremo-Potparević. (2017) Unexpected effect of dry olive leaf extract on the level of DNA damage in lymphocytes of lead intoxicated workers, before and after CaNa 2 EDTA chelation therapy. Food and Chemical Toxicology 106, pages 616-623.
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Nisha Singh, Jacky Bhagat & Baban S. Ingole. (2017) Genotoxicity of two heavy metal compounds: lead nitrate and cobalt chloride in Polychaete Perinereis cultrifera. Environmental Monitoring and Assessment 189:7.
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Hyun Soo Kim, Sang Min Lee, Yeo Jin Kim, Wonhee Jang & Young Rok Seo. (2017) Integrative toxicogenomic analysis for elucidating molecular interference on DNA integrity and repair system with underlying signaling networks in response to low-level lead acetate in rat liver model. Molecular & Cellular Toxicology 13:2, pages 179-188.
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G.X. Sun, Y. Chen, C. P. Liu, S. Li & J. Fu. (2016) Effect of Selenium Against Lead-Induced Damage on the Gene Expression of Heat Shock Proteins and Inflammatory Cytokines in Peripheral Blood Lymphocytes of Chickens. Biological Trace Element Research 172:2, pages 474-480.
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Chibuisi G. Alimba, Varinderpal Dhillon, Adekunle A. Bakare & Michael Fenech. (2016) Genotoxicity and cytotoxicity of chromium, copper, manganese and lead, and their mixture in WIL2-NS human B lymphoblastoid cells is enhanced by folate depletion. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 798-799, pages 35-47.
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Chun-Feng Lu, Xiao-Yan Yuan, Li-Zhong Li, Wei Zhou, Jun Zhao, Yi-Mei Wang & Shuang-Qing Peng. (2015) Combined exposure to nano-silica and lead induced potentiation of oxidative stress and DNA damage in human lung epithelial cells. Ecotoxicology and Environmental Safety 122, pages 537-544.
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Aida I. El Makawy, Ihab S. Ashoush & Omaima M. Abd-Elmoneim. (2015) Evaluation of Mango Byproduct Extracts as Antioxidant Against Pb-Acetate-Induced Oxidative Stress and Genotoxicity in Mice. Polish Journal of Food and Nutrition Sciences 65:1.
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Margarita Topashka-Ancheva, Michaela Beltcheva, Roumiana Metcheva, J. Antonio Heredia Rojas, Abraham O. Rodriguez-De la Fuente, Tsvetelina Gerasimova, Laura E. Rodríguez-Flores & Svetla E. Teodorova. (2011) Modified Natural Clinoptilolite Detoxifies Small Mammal’s Organism Loaded with Lead II: Genetic, Cell, and Physiological Effects. Biological Trace Element Research 147:1-3, pages 206-216.
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Okunola A. Alabi, Adekunle A. Bakare, Xijin Xu, Bin Li, Yuling Zhang & Xia Huo. (2012) Comparative evaluation of environmental contamination and DNA damage induced by electronic-waste in Nigeria and China. Science of The Total Environment 423, pages 62-72.
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Minerva Martínez-Alfaro, Daniel Hernández-Cortés, Katarzyna Wrobel, Gustavo Cruz-Jiménez, Julio Cesar Rivera-Leyva, Rosa María Piña-Zentella & Alfonso Cárabez Trejo. (2012) Effect of melatonin administration on DNA damage and repair responses in lymphocytes of rats subchronically exposed to lead. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 742:1-2, pages 37-42.
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Erico R. Carmona, Amadeu Creus & Ricard Marcos. (2011) Genotoxicity testing of two lead-compounds in somatic cells of Drosophila melanogaster. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 724:1-2, pages 35-40.
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Renata Szyguła, Andrzej Bunio & Sławomir Tubek. (2010) The Content of Elements in Rainwater and Its Relation to the Frequency of Hospitalization for Chronic Lymphocytic Leukemia and Chronic Myeloid Leukemia in Opole Voivodship, Poland, During 2000–2002. Biological Trace Element Research 141:1-3, pages 41-52.
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David Kirkland, Lesley Reeve, David Gatehouse & Philippe Vanparys. (2011) A core in vitro genotoxicity battery comprising the Ames test plus the in vitro micronucleus test is sufficient to detect rodent carcinogens and in vivo genotoxins. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 721:1, pages 27-73.
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K. Narayana & Maie Al-Bader. (2011) Ultrastructural and DNA damaging effects of lead nitrate in the liver. Experimental and Toxicologic Pathology 63:1-2, pages 43-51.
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Julia García-Lestón, Josefina Méndez, Eduardo Pásaro & Blanca Laffon. (2010) Genotoxic effects of lead: An updated review. Environment International 36:6, pages 623-636.
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Minerva Martínez‐Alfaro, Alfonso Cárabez‐Trejo, Marco‐Antonio Gallegos‐Corona, Gustavo Pedraza‐Aboytes, Nancy Georgina Hernández‐Chan & Guillermo Enrique Leo‐Amador. (2009) Thinner inhalation effects on oxidative stress and DNA repair in a rat model of abuse. Journal of Applied Toxicology 30:3, pages 226-232.
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Paramjit Grover, P.V. Rekhadevi, K. Danadevi, S.B. Vuyyuri, M. Mahboob & M.F. Rahman. (2010) Genotoxicity evaluation in workers occupationally exposed to lead. International Journal of Hygiene and Environmental Health 213:2, pages 99-106.
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Abjal Pasha Shaik & Kaiser Jamil. (2009) Individual susceptibility and genotoxicity in workers exposed to hazardous materials like lead. Journal of Hazardous Materials 168:2-3, pages 918-924.
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Joaquim Torres Tapisso, Carla Cristina Marques, Maria da Luz Mathias & Maria da Graça Ramalhinho. (2009) Induction of micronuclei and sister chromatid exchange in bone-marrow cells and abnormalities in sperm of Algerian mice (Mus spretus) exposed to cadmium, lead and zinc. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 678:1, pages 59-64.
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AP Shaik, M Khan & K Jamil. (2009) Phylogenetic analysis of ALAD and MGP genes related to lead toxicity. Toxicology and Industrial Health 25:6, pages 403-409.
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A. Ustundag & Y. Duydu. (2008) Induction of Excision Repairable DNA Lesions in Lymphocytes Exposed to Lead and ALA In Vitro. Biological Trace Element Research 128:1, pages 31-37.
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AP Shaik & K Jamil. (2008) A study on the ALAD gene polymorphisms associated with lead exposure. Toxicology and Industrial Health 24:7, pages 501-506.
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Adekunle A. Bakare, Alok K. Pandey, Mahima Bajpayee, Devyani Bhargav, Debapratim Kar Chowdhuri, Kunwar P. Singh, Ramesh C. Murthy & Alok Dhawan. (2006) DNA damage induced in human peripheral blood lymphocytes by industrial solid waste and municipal sludge leachates. Environmental and Molecular Mutagenesis 48:1, pages 30-37.
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