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Drug and Chemical Toxicology Volume 43, 2020 - Issue 2
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Research Articles

In vitro cytotoxicity of polyphenols from Datura innoxia aqueous leaf-extract on human leukemia K562 cells: DNA and nuclear proteins as targets

Elham ChamaniCardiovascular Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran; ;Department of Biochemistry, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran; Correspondence[email protected]
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Roshanak EbrahimiDepartment of Biochemistry, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran; View further author information
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Khatereh KhorsandiDepartment of Photodynamic, Medical Laser Research Center, YARA institute, ACECR, Tehran, Iran; Correspondence[email protected]
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Azadeh MeshkiniDepartment of Chemistry, Faculty of Science, Ferdowsi University of Mashhad, Mashhad, Iran; View further author information
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Asghar ZarbanDepartment of Biochemistry, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran; View further author information
&
Gholamreza SharifzadehSocial Determinants of Health Research Center, Birjand University of Medical Sciences, Birjand, IranView further author information
Pages 138-148 | Received 16 Feb 2019, Accepted 02 Jun 2019, Published online: 19 Jul 2019

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Mohammadreza Abdihaji, Masoumeh Mirzaei Chegeni, Alireza Hadizadeh, Negar Farrokhzad, Zahra Kheradmand, Parastoo Fakhrfatemi, Fardad Faress, Kasra Moeinabadi-Bidgoli, Hassan Noorbazargan & Ebrahim Mostafavi. (2023) Polyvinyl Alcohol (PVA)-Based Nanoniosome for Enhanced in vitro Delivery and Anticancer Activity of Thymol. International Journal of Nanomedicine 18, pages 3459-3488.
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Elham Chamani, Zohreh Rezaei, Kazem Dastjerdi, Setareh Javanshir, Khatereh Khorsandi & Gholam Abbas Mohammadi. (2020) Evaluation of some genes and proteins involved in apoptosis on human chronic myeloid leukemia cells (K562 cells) by datura innoxia leaves aqueous extract. Journal of Biomolecular Structure and Dynamics 38:16, pages 4838-4849.
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Wenwen Lian, Yuwei Wang, Jia Zhang, Yu Yan, Congyuan Xia, He Gan, Xiaoyan Wang, Ting Yang, Jiekun Xu, Jun He & Weiku Zhang. (2022) The genus Datura L. (Solanaceae): A systematic review of botany, traditional use, phytochemistry, pharmacology, and toxicology. Phytochemistry 204, pages 113446.
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Bhuwan C. Joshi, Vijay Juyal, Archana N. Sah, Piyush Verma & Minky Mukhija. (2022) Review on Documented Medicinal Plants used for the Treatment of Cancer. Current Traditional Medicine 8:2.
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Tomasz Kowalczyk, Anna Merecz-Sadowska, Patricia Rijo, Mattia Mori, Sophia Hatziantoniou, Karol Górski, Janusz Szemraj, Janusz Piekarski, Tomasz Śliwiński, Michał Bijak & Przemysław Sitarek. (2022) Hidden in Plants—A Review of the Anticancer Potential of the Solanaceae Family in In Vitro and In Vivo Studies. Cancers 14:6, pages 1455.
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Mohammed Al-Zharani, Fahd A. Nasr, Ali S. Alqahtani, Mary Anne W. Cordero, Amal A. Alotaibi, Asmatanzeem Bepari, Saud Alarifi, Ali Daoud, Ibrahim O. Barnawi & Haytham M. Daradka. (2021) In Vitro Cytotoxic Evaluation and Apoptotic Effects of Datura innoxia Grown in Saudi Arabia and Phytochemical Analysis. Applied Sciences 11:6, pages 2864.
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Nosheen Akhtar, Muhammad Waleed Baig, Ihsan-ul Haq, Vinothini Rajeeve & Pedro Rodriguez Cutillas. (2020) Withanolide Metabolites Inhibit PI3K/AKT and MAPK Pro-Survival Pathways and Induce Apoptosis in Acute Myeloid Leukemia Cells. Biomedicines 8:9, pages 333.
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