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Research Articles

In vitro cytotoxicity of polyphenols from Datura innoxia aqueous leaf-extract on human leukemia K562 cells: DNA and nuclear proteins as targets

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Pages 138-148 | Received 16 Feb 2019, Accepted 02 Jun 2019, Published online: 19 Jul 2019

References

  • Afolayan, A, and Wintola, O., 2011. Phytochemical constituents and antioxidant activities of the whole leaf extract of Aloe ferox Mill. Pharmacognosy Magazine, 7 (28), 325.
  • Arulvasu, C., et al., 2014. Purification and identification of bioactive protein from leaves of Datura inoxia P.mil. Biomedicine & Preventive Nutrition, 4 (2), 143–149.
  • Ashrafi, M., et al., 2005. The effect of carotenoids obtained from saffron on histone H1 structure and H1–DNA interaction. International Journal of Biological Macromolecules, 36 (4), 246–252.
  • Banerjee, A., et al., 2017. The plant alkaloid chelerythrine binds to chromatin, alters H3K9Ac and modulates global gene expression. Journal of Biomolecular Structure and Dynamics, 35 (7), 1491–1499.
  • Bathaie, S.Z., et al., 2007. Interaction of saffron carotenoids as anticancer compounds with ctDNA, Oligo (dG.dC) 15, and Oligo (dA.dT) 15. DNA and Cell Biology, 26 (8), 533–540.
  • Bhardwaj, K., Kumar, S., and Ojha, S., 2016. Antioxidant activity and FT-IR analysis of Datura innoxia and Datura metel leaf and seed methanolic extracts. African Journal of Traditional, Complementary and Alternative Medicines, 13 (5), 7–16.
  • Cheshomi, H., Aldaghi, L.S., and Rezaei Seresht, H., 2016. Cytotoxicity of the methanol extract of Datura innoxia petals on MCF-7 and HEK-293 cell lines. Journal of Biomedicine, 1 (2).
  • Cragg, G.M., and Newman, D.J., 2000. Antineoplastic agents from natural sources: achievements and future directions. Expert Opinion on Investigational Drugs, 9 (12), 2783–2797.
  • Dai, J., and Mumper, R.J., 2010. Plant phenolics: extraction, analysis and their antioxidant and anticancer properties. Molecules, 15 (10), 7313–7352.
  • De Wolf, G.P., 1956. Notes on cultivated Solanaceae. 2. Datura. Baileya, 4, 13–23.
  • Dehghan, G., et al., 2011. Spectroscopic studies on the interaction of Quercetin–Terbium(III) complex with Calf Thymus DNA. DNA and Cell Biology, 30 (3), 195–201.
  • Dixon, J.R., Gorkin, D.U., and Ren, B., 2016. Chromatin domains: the unit of chromosome organization. Molecular Cell, 62 (5), 668–680.
  • Fatima, H., et al., 2015. Extraction optimization of medicinally important metabolites from Datura innoxia Mill.: an in vitro biological and phytochemical investigation. BMC Complementary and Alternative Medicine, 15 (1), 376.
  • Hübner, M.R., Eckersley-Maslin, M.A., and Spector, D.L., 2013. Chromatin organization and transcriptional regulation. Current Opinion in Genetics & Development, 23 (2), 89–95.
  • Hurley, L.H., and Boyd, F.L., 1988. DNA as a target for drug action. Trends in Pharmacological Sciences, 9 (11), 402–407.
  • Jabbour, E., and Kantarjian, H., 2018. Chronic myeloid leukemia: 2018 update on diagnosis, therapy and monitoring. American Journal of Hematology, 93 (3), 442–459.
  • Kalashnikova, A.A., Rogge, R.A., and Hansen, J.C., 2016. Linker histone H1 and protein-protein interactions. Biochimica et Biophysica Acta, 1859 (3), 455–461.
  • Kashanian, S., and Dolatabadi, J.E.N., 2009. DNA binding studies of 2-tert-butylhydroquinone (TBHQ) food additive. Food Chemistry, 116 (3), 743–747.
  • Kayani, S., et al., 2014. Ethnobotanical uses of medicinal plants for respiratory disorders among the inhabitants of Gallies – Abbottabad, Northern Pakistan. Journal of Ethnopharmacology, 156, 47–60.
  • Lin, J.-Y., and Tang, C.-Y., 2007. Determination of total phenolic and flavonoid contents in selected fruits and vegetables, as well as their stimulatory effects on mouse splenocyte proliferation. Food Chemistry, 101 (1), 140–147.
  • Lobo, V., et al., 2010. Free radicals, antioxidants and functional foods: impact on human health. Pharmacognosy Reviews, 4 (8), 118.
  • Mosmann, T., 1983. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. Journal of Immunological Methods, 65 (1–2), 55–63.
  • Mostafavinia, S.E., and Hoshyar, R., 2016. Spectroscopic studies on the interaction of anti cancer rosemary with ctDNA. Gene, Cell and Tissue, 3 (2), e35638.
  • Nair, S.S., and Kumar, R., 2012. Chromatin remodeling in cancer: a gateway to regulate gene transcription. Molecular Oncology, 6 (6), 611–619.
  • Maheshwari, N.O., and Khan, A., and Balu A. C. 2013. Rediscovering the medicinal properties of Datura sp.: a review. Journal of Medicinal Plants Research. 7 (39), 2885–2897.
  • Preedy, V. (Ed.). (2016). Neuropathology of Drug Addictions and Substance Misuse, Volume 2 (1st Edition). New York: Academic Press. Retrieved from https://www.elsevier.com/books/neuropathology-of-drug-addictions-and-substance-misuse-volume-2/preedy/978-0-12-800212-4
  • Quansah, E., and Karikari, T.K., 2016. Potential role of metabolomics in the improvement of research on traditional African medicine. Phytochemistry Letters, 17, 270–277.
  • Russo, G.L., et al., 2017. Dietary polyphenols and chromatin remodeling. Critical Reviews in Food Science and Nutrition, 57 (12), 2589–2599.
  • Sak, K., and Everaus, H., 2016. Established human cell lines as models to study anti-leukemic effects of flavonoids. Current Genomics, 18 (1), 3–26.
  • Sasaki, T., et al., 2002. Inhibition of proliferation and induction of differentiation of glioma cells with Datura stramonium agglutinin. British Journal of Cancer, 87 (8), 918–923.
  • Schultes, R.E., and Hofmann, A., 1979. Plants of the gods: their sacred, healing, and hallucinogenic powers. Rochester: Healing Arts Press. Retrieved from https://books.google.com/books?id=XyR0QgAACAAJ
  • Shabestari, M., and Samarghandian, S., 2013. DNA fragmentation and apoptosis induced by safranal in human prostate cancer cell line. Indian Journal of Urology, 29 (3), 177.
  • Sirajuddin, M., Ali, S., and Badshah, A., 2013. Drug–DNA interactions and their study by UV–Visible, fluorescence spectroscopies and cyclic voltametry. Journal of Photochemistry and Photobiology B: Biology, 124, 1–19.
  • Soni, P., et al., 2012. Pharmacological properties of Datura stramonium L. as a potential medicinal tree: an overview. Asian Pacific Journal of Tropical Biomedicine, 2 (12), 1002–1008.
  • Śramska, P., et al., 2017. Isolation of atropine and scopolamine from plant material using liquid-liquid extraction and EXtrelut® columns. Journal of Chromatography B, 1043, 202–208.
  • Sun, B., Ricardo-da-Silva, J.M., and Spranger, I., 1998. Critical factors of vanillin assay for catechins and proanthocyanidins. Journal of Agricultural and Food Chemistry, 46 (10), 4267–4274.
  • Yang, B.-Y., et al., 2014. New antiproliferative and immunosuppressive withanolides from the seeds of Datura metel. Phytochemistry Letters, 8, 92–96.
  • Zhou, Y., et al., 2016. Natural polyphenols for prevention and treatment of cancer. Nutrients, 8 (8), 515.

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