65
Views
71
CrossRef citations to date
0
Altmetric
Original Articles

Evaluation of A Chiral Crown Etherlc Column For the Separation of Racemic Amines

&
Pages 9-28 | Published online: 23 Oct 2006

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (9)

Guy Felix & Alain Berthod. (2007) Commercial Chiral Stationary Phases for the Separations of Clinical Racemic Drugs. Separation & Purification Reviews 36:4, pages 285-481.
Read now
Hee Jung Choi & Myung Ho Hyun. (2007) Liquid Chromatographic Chiral Separations by Crown Ether‐Based Chiral Stationary Phases. Journal of Liquid Chromatography & Related Technologies 30:5-7, pages 853-875.
Read now
S. Chen, H. Yuan, N. Grinberg, A. Dovletoglou & G. Bicker. (2003) Enantiomeric Separation of trans‐2‐Aminocyclohexanol on a Crown Ether Stationary Phase Using Evaporative Light Scattering Detection. Journal of Liquid Chromatography & Related Technologies 26:3, pages 425-442.
Read now
B. Soontornniyomkij , K. Scandrett & D.J. Pietrzyk. (1998) Capillary Zone Electrophoresis Separation of Amino Acid Enantiomers as Dansylated Derivatives Through Control of Electroosmotic Flow. Journal of Liquid Chromatography & Related Technologies 21:15, pages 2245-2263.
Read now
BrianS. Kersten. (1994) HPLC Chiral Optimization of a Unique β-Amino Acid and Its Ester. Journal of Liquid Chromatography 17:1, pages 33-48.
Read now
San Chun Chang, LisaR. Wang & DanielW. Armstrong. (1992) Facile Resolution OF N-tert-Butoxy-Carbonyl Amino Acids: The Importance of Enantiomeric Purity in Peptide Synthesis. Journal of Liquid Chromatography 15:9, pages 1411-1429.
Read now
Martha Hilton & DanielW. Armstrong. (1991) Evaluation of the Enantiomeric Separation of Dipeptides Using a Chiral Crown Ether LC Column. Journal of Liquid Chromatography 14:20, pages 3673-3683.
Read now

Articles from other publishers (62)

Sepideh Khaki Firooz, Joshua Putman, Brandon Fulton, Carl J. Lovely, Alain Berthod & Daniel W. Armstrong. (2022) Liquid chromatography enantiomeric separation of chiral ethanolamine substituted compounds. Chirality 34:4, pages 620-629.
Crossref
Marziyeh E. Kenari, Joshua I. Putman, Ravi P. Singh, Brandon B. Fulton, Huy Phan, Reem K. Haimour, Key Tse, Alain Berthod, Carl J. Lovely & Daniel W. Armstrong. (2021) Enantiomeric Separation of New Chiral Azole Compounds. Molecules 26:1, pages 213.
Crossref
Daipayan Roy & Daniel W. Armstrong. (2019) Fast super/subcritical fluid chromatographic enantioseparations on superficially porous particles bonded with broad selectivity chiral selectors relative to fully porous particles. Journal of Chromatography A 1605, pages 360339.
Crossref
Nada F. Atta, Ahmed Galal & Yousef M. Ahmed. (2019) Highly Conductive Crown Ether/Ionic Liquid Crystal-Carbon Nanotubes Composite Based Electrochemical Sensor for Chiral Recognition of Tyrosine Enantiomers. Journal of The Electrochemical Society 166:8, pages B623-B630.
Crossref
Garrett Hellinghausen & Daniel W. Armstrong. 2019. Chiral Separations. Chiral Separations 183 200 .
Yeeun Lim, Zachary S. Breitbach, Daniel W. Armstrong & Alain Berthod. (2016) Screening primary racemic amines for enantioseparation by derivatized polysaccharide and cyclofructan columns. Journal of Pharmaceutical Analysis 6:6, pages 345-355.
Crossref
Chunhua Zhao, Xiaohua Zhou, Yan Xiao, Dan Wang, Zhen Zhou, Zhixiong Yang, Xiaoqin Jiang & Jiang Wang. (2015) Mechanisms of L‐lysine extraction with sec‐octylphenoxy acetic acid in sulfonated kerosene. Journal of Chemical Technology & Biotechnology 91:7, pages 2047-2055.
Crossref
Dongqiang Wang, Jianchao Zhao, Haixia Wu, Haibo Wu, Jianfeng Cai, Yanxiong Ke & Xinmiao Liang. (2014) Preparation and evaluation of novel chiral stationary phases based on quinine derivatives comprising crown ether moieties. Journal of Separation Science 38:2, pages 205-210.
Crossref
Ping Sun, Chunlei Wang, Nilusha Lasanthi Thilakarathna Padivitage, Yasith S. Nanayakkara, Sirantha Perera, Haixiao Qiu, Ying Zhang & Daniel W. Armstrong. (2011) Evaluation of aromatic-derivatized cyclofructans 6 and 7 as HPLC chiral selectors. The Analyst 136:4, pages 787-800.
Crossref
Ping Sun & Daniel W. Armstrong. (2010) Effective enantiomeric separations of racemic primary amines by the isopropyl carbamate-cyclofructan6 chiral stationary phase. Journal of Chromatography A 1217:30, pages 4904-4918.
Crossref
Ping Sun, Chunlei Wang, Zachary S. Breitbach, Ying Zhang & Daniel W. Armstrong. (2009) Development of New HPLC Chiral Stationary Phases Based on Native and Derivatized Cyclofructans. Analytical Chemistry 81:24, pages 10215-10226.
Crossref
Chunxia Jiang, Man‐Yung Tong, Zachary S. Breitbach & Daniel W. Armstrong. (2009) Synthesis and examination of sulfated cyclofructans as a novel class of chiral selectors for CE. ELECTROPHORESIS 30:22, pages 3897-3909.
Crossref
Ya-Li Hsiao & Shushi Chen. (2009) LC Separation of Enantiomers on Silica-Bonded Thiostrepton Derivatives. Chromatographia 70:7-8, pages 1031-1038.
Crossref
Marie Lecoeur‐Lorin, Raphaël Delépée & Philippe Morin. (2009) Sensitivity improvement by using contactless conductivity rather than indirect UV detection for the determination of enantiomeric purity of amines by CE. ELECTROPHORESIS 30:3, pages 487-498.
Crossref
Xiao Yang Gong & Peter C. Hauser. (2006) Enantiomeric separation of underivatized small amines in conventional and on‐chip capillary electrophoresis with contactless conductivity detection. ELECTROPHORESIS 27:21, pages 4375-4382.
Crossref
Myung Ho Hyun. 2006. Chiral Separation Techniques. Chiral Separation Techniques 275 299 .
Viktor Farkas, Tünde Tóth, György Orosz, Péter Huszthy & Miklós Hollósi. (2006) Enantioseparation of protonated primary arylalkylamines and amino acids containing an aromatic moiety on a pyridino-crown ether based new chiral stationary phase. Tetrahedron: Asymmetry 17:12, pages 1883-1889.
Crossref
Uwe Conrad, Bezhan Chankvetadze & Gerhard K. E. Scriba. (2005) High performance liquid chromatographic separation of dipeptide and tripeptide enantiomers using a chiral crown ether stationary phase. Journal of Separation Science 28:17, pages 2275-2281.
Crossref
János Elek, Debby Mangelings, Timea Iványi, István Lázár & Y. Vander Heyden. (2005) Enantioselective capillary electrophoretic separation of tryptophane- and tyrosine-methylesters in a dual system with a tetra-oxadiaza-crown-ether derivative and a cyclodextrin. Journal of Pharmaceutical and Biomedical Analysis 38:4, pages 601-608.
Crossref
Keiji Hirose, Jin Yongzhu, Takashi Nakamura, Ryota Nishioka, Tetsuro Ueshige & Yoshito Tobe. (2005) Preparation and evaluation of a chiral stationary phase covalently bound with chiral pseudo-18-crown-6 ether having 1-phenyl-1,2-cyclohexanediol as a chiral unit. Journal of Chromatography A 1078:1-2, pages 35-41.
Crossref
Keiji Hirose, Jin Yongzhu, Takashi Nakamura, Ryota Nishioka, Tetsuro Ueshige & Yoshito Tobe. (2005) Chiral stationary phase covalently bound with a chiral pseudo‐18‐crown‐6 ether for enantiomer separation of amino compounds using a normal mobile phase. Chirality 17:3, pages 142-148.
Crossref
S. Chen. (2004) The HPLC Stereoselective Resolution of N-2,4-Dinitrophenylated (DNP) Amine-Containing Enantiomers on Teicoplanin Bonded Phase Using the Methanol-Based Mobile Phase. Chromatographia 59:3-4, pages 173-180.
Crossref
Hassan Aboul-Enein & Imran Ali. 2003. Chiral Separations By Liquid Chromatography And Related Technologies. Chiral Separations By Liquid Chromatography And Related Technologies 281 300 .
Myung Ho Hyun. (2003) Characterization of liquid chromatographic chiral separation on chiral crown ether stationary phases. Journal of Separation Science 26:3-4, pages 242-250.
Crossref
Shushi Chen. (2013) The HPLC Enantioresolution of Selected Native or Derivatized Amino Acids on Teicoplanin Bonded Chiral Stationary Phase Using a Methanol‐Based Mobile Phase. Journal of the Chinese Chemical Society 49:4, pages 545-551.
Crossref
Robert J. Steffeck, Yury Zelechonok & Kyung H. Gahm. (2002) Enantioselective separation of racemic secondary amines on a chiral crown ether-based liquid chromatography stationary phase. Journal of Chromatography A 947:2, pages 301-305.
Crossref
A. Péter, E. Vékes, L. Gera, J. M. Stewart & D. W. Armstrong. (2002) A comparison of the direct and indirect LC methods for separating enantiomers of unusual glycine and alanine amino acid analogues. Chromatographia 56:1, pages S79-S89.
Crossref
A. Sanz-Medel & E. Blanco-González. (2001) Chiral speciation of trace elements: approaches to the speciation of selenoaminoacid enantiomers in biological samples. J. Anal. At. Spectrom. 16:9, pages 957-963.
Crossref
Charles W. Gehrke, Robert L. Wixom & Ernst Bayer. 2001. chromatography a century of discovery 1900–2000 - the bridge to the sciences/technology. chromatography a century of discovery 1900–2000 - the bridge to the sciences/technology 99 599 .
Apryll M. Stalcup. 2001. Kirk-Othmer Encyclopedia of Chemical Technology. Kirk-Othmer Encyclopedia of Chemical Technology.
H. Y. Aboul-Enein & I. Ali. (2000) Macrocyclic antibiotics as effective chiral selectors for enantiomeric resolution by liquid chromatography and capillary electrophoresis. Chromatographia 52:11-12, pages 679-691.
Crossref
E. Peyrin, Y. C. Guillaume, A. Villet, A. Ravel, C. Grosset & J. Alary. (2000) 18-crown-6-aminophenol isomer complexes studied by RPLC. Chromatographia 52:9-10, pages 584-588.
Crossref
G. Török, A. Péter, E. Vékes, J. Sápi, M. Laronze, J. -Y. Laronze & D. W. Armstrong. (2000) Enantiomeric high-performance liquid chromatographic separation of β-substituted tryptophan analogues. Chromatographia 51:1, pages S165-S174.
Crossref
György Horváth & Péter Huszthy. (1999) Chromatographic enantioseparation of racemic α-(1-naphthyl)ethylammonium perchlorate by a Merrifield resin-bound enantiomerically pure chiral dimethylpyridino-18-crown-6 ligand. Tetrahedron: Asymmetry 10:23, pages 4573-4583.
Crossref
Reinhard Kuhn. (1999) Enantiomeric separation by capillary electrophoresis using a crown ether as chiral selector. Electrophoresis 20:13, pages 2605-2613.
Crossref
Zoltán Köntös, Péter Huszthy, Jerald S. Bradshaw & Reed M. Izatt. (1999) Enantioseparation of racemic organic ammonium perchlorates by a silica gel bound optically active di-tert-butylpyridino-18-crown-6 ligand. Tetrahedron: Asymmetry 10:11, pages 2087-2099.
Crossref
Y. Machida, H. Nishi & K. Nakamura. (1999) Separation of the enantiomers of amino and amide compounds on novel chiral stationary phases derived from a crown ether. Chromatographia 49:11-12, pages 621-627.
Crossref
Eva Tesařová, Zuzana Bosáková & Věra Pacáková. (1999) Comparison of enantioselective separation of N-tert.-butyloxycarbonyl amino acids and their non-blocked analogues on teicoplanin-based chiral stationary phase. Journal of Chromatography A 838:1-2, pages 121-129.
Crossref
Shushi Chen. (2013) High Performance Liquid Chromatographic Enantioresolution of Benzoyl Amino Acid, Dipeptides and Tripeptide on β‐Cyclodextrin Bonded Stationary Phase Using Polar‐Organic Acetonitrile as the Mobile Phase. Journal of the Chinese Chemical Society 46:2, pages 239-244.
Crossref
Milada Doležalová & Magda Tkaczyková. (1999) Direct high-performance liquid chromatographic determination of the enantiomeric purity of levodopa and methyldopa: comparison with pharmacopoeial polarimetric methods. Journal of Pharmaceutical and Biomedical Analysis 19:3-4, pages 555-567.
Crossref
Daniel W. Armstrong. (2013) The Evolution of Chiral Stationary Phases for Liquid Chromatography. Journal of the Chinese Chemical Society 45:5, pages 581-590.
Crossref
G. Török, A. Péter & F. Fülöp. (1998) High-Performance liquid chromatographic separation of enantiomers of unusual amino acids possessing cycloalkane or cycloalkene skeletons on a chiral crown ether containing stationary phase. Chromatographia 48:1-2, pages 20-26.
Crossref
L Lecointe, V Rolland-Fulcrand, M.L Roumestant, Ph Viallefont & J Martinez. (1998) Chemoenzymatic synthesis of the two enantiomers of 7-azatryptophan. Tetrahedron: Asymmetry 9:10, pages 1753-1758.
Crossref
Bogusław Buszewski, Marta Jezierska, Mirosław Wełniak & Dušan Berek. (1998) Survey and Trends in the Preparation of Chemically Bonded Silica Phases for Liquid Chromatographic Analysis. Journal of High Resolution Chromatography 21:5, pages 267-281.
Crossref
Gabriella Török, Antal Péter, Peter Csomós, Liisa T Kanerva & Ferenc Fülöp. (1998) High-performance liquid chromatographic methods for separation of the isomers of β-amino acids possessing bicyclo[2.2.1]heptane or heptene skeletons. Journal of Chromatography A 797:1-2, pages 177-186.
Crossref
Eva TESAŘOVÁ & Daniel W. ARMSTRONG. 1998. Advanced Chromatographic and Electromigration Methods in BioSciences. Advanced Chromatographic and Electromigration Methods in BioSciences 197 256 .
Lana E. Janes & Romas J. Kazlauskas. (1997) Empirical rules for the enantiopreference of lipase from Aspergillus niger toward secondary alcohols and carboxylic acids, especially α-amino acids. Tetrahedron: Asymmetry 8:22, pages 3719-3733.
Crossref
Xi‐Chun Zhou, Cai‐Ying Wu, Hui Yan & Yuan‐Yin Chen. (2005) Gas chromatographic enantiomer separation on polysiloxane‐anchored chiral crown ether (Chirasil‐man‐18C6‐25). Journal of High Resolution Chromatography 19:11, pages 643-646.
Crossref
Alain Berthod, Youbang Liu, Christina Bagwill & Daniel W. Armstrong. (1996) Facile liquid chromatographic enantioresolution of native amino acids and peptides using a teicoplanin chiral stationary phase. Journal of Chromatography A 731:1-2, pages 123-137.
Crossref
Shushi Chen. (2013) The Enantioresolution of n ‐Benzoyl and Its Analogs Derivatized Amino Acids on Cyclodextrin Bonded Chiral Stationary Phases Using a Nonaqueous Acetonitrile‐Based Mobile Phase . Journal of the Chinese Chemical Society 43:1, pages 45-51.
Crossref
Martin G. Schmid & Gerald Gübitz. (1995) Capillary zone electrophoretic separation of the enantiomers of dipeptides based on host-guest complexation with a chiral crown ether. Journal of Chromatography A 709:1, pages 81-88.
Crossref
Thomas SchmittThomas Schmitt. 1995. Beiträge zur Enantiomerentrennung in der Kapillarelektrophorese. Beiträge zur Enantiomerentrennung in der Kapillarelektrophorese 234 240 .
Zdzislaw Chilmonczyk, Hanna Ksycińska & Jacek Cybulski. (2006) Direct Determination of the Enantiomeric Purity of ( R )‐(+)‐Aminoglutethimide and its Main Metabolite . Archiv der Pharmazie 328:11-12, pages 745-749.
Crossref
A. A. Prokopov & L. N. Yakhontov. (1994) Chemistry of the azaindoles (review). Pharmaceutical Chemistry Journal 28:7, pages 471-506.
Crossref
Reed M. Izatt, Xian Xin Zhang, Peter Huszthy, Cheng Y. Zhu, Jon K. Hathaway, Tingmin Wang & Jerald S. Bradshaw. (1994) A thermodynamic study of enantiomeric recognition of organic ammonium cations by pyridino-18-crown-6 type ligands in methanol and a 1: 1 methanol-1,2-dichloroethane mixture at 25.0�C. Journal of Inclusion Phenomena and Molecular Recognition in Chemistry 18:4, pages 353-367.
Crossref
Pierfrancesco Castelnovo. (2004) Determination of the enantiomeric purity of 5,6‐ and 6,7‐dihydroxy‐2‐aminotetralins by chiral HPLC. Chirality 5:3, pages 181-187.
Crossref
Evelyne Höhne, Gerd‐Joachim Krauss & Gerald Gübitz. (2005) Capillary zone electrophoresis of the enantiomers of aminoalcohols based on host‐guest complexation with a chiral crown ether. Journal of High Resolution Chromatography 15:10, pages 698-700.
Crossref
Franco M. Pasutto. (2013) Mirror Images: The Analysis of Pharmaceutical Enantiomers. The Journal of Clinical Pharmacology 32:10, pages 917-924.
Crossref
J. Gordon Adamson, Thang Hoang, Anna Crivici & Gilles A. Lajoie. (1992) Use of Marfey's reagent to quantitate racemization upon anchoring of amino acids to solid supports for peptide synthesis. Analytical Biochemistry 202:1, pages 210-214.
Crossref
R. Kuhn, F. Stoecklin & F. Erni. (1992) Chiral separations by host-guest complexation with cyclodextrin and crown ether in capillary zone electrophoresis. Chromatographia 33:1-2, pages 32-36.
Crossref
Benjamin Esquivel, Lawrence Nicholson, Linda Peerey & Michael Fazio. (2005) Enantiomeric resolution of underivatized small peptides by HPLC with a chiral crown ether stationary phase. Journal of High Resolution Chromatography 14:12, pages 816-823.
Crossref
D. W. Armstrong, J. D. Duncan & S. H. Lee. (1991) Evaluation of D-amino acid levels in human urine and in commercial L-amino acid samples. Amino Acids 1:1, pages 97-106.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.