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Neurological Research
A Journal of Progress in Neurosurgery, Neurology and Neurosciences
Volume 43, 2021 - Issue 5
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Original Research Paper

NF-κB 1-induced LINC00665 regulates inflammation and apoptosis of neurons caused by spinal cord injury by targeting miR-34a-5p

Qilong Denga Rehabilitation Medical Center, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, China;b Rehabilitation Medical Center, Luqiao Hospital, Taizhou Enze Medical Center (Group), Taizhou, Zhejiang, ChinaCorrespondence[email protected]
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Lili Maa Rehabilitation Medical Center, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, China;b Rehabilitation Medical Center, Luqiao Hospital, Taizhou Enze Medical Center (Group), Taizhou, Zhejiang, ChinaView further author information
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Ting Chena Rehabilitation Medical Center, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, China;b Rehabilitation Medical Center, Luqiao Hospital, Taizhou Enze Medical Center (Group), Taizhou, Zhejiang, ChinaView further author information
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Yu Yanga Rehabilitation Medical Center, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, China;b Rehabilitation Medical Center, Luqiao Hospital, Taizhou Enze Medical Center (Group), Taizhou, Zhejiang, ChinaView further author information
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Yuetao Maa Rehabilitation Medical Center, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, China;b Rehabilitation Medical Center, Luqiao Hospital, Taizhou Enze Medical Center (Group), Taizhou, Zhejiang, ChinaView further author information
&
Lizhong Maa Rehabilitation Medical Center, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, China;b Rehabilitation Medical Center, Luqiao Hospital, Taizhou Enze Medical Center (Group), Taizhou, Zhejiang, ChinaCorrespondence[email protected]
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Pages 418-427 | Received 13 Aug 2020, Accepted 12 Dec 2020, Published online: 12 Jan 2021

Citations (14)

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Xing Guo, Jindong He, Rongping Zhang, Tiechui Wang, Jinjin Chen, Jinyu Wang, Zihang Wang, Guan Chang, Yubo Niu, Zhiyong Niu & Junjie Song. (2022) N-Acetylcysteine alleviates spinal cord injury in rats after early decompression surgery by regulating inflammation and apoptosis. Neurological Research 44:7, pages 605-613.
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Zhiyan Wang, Qijun Tian, Yumei Tian & Zhonghua Zheng. (2022) MicroRNA-122-3p plays as the target of long non-coding RNA LINC00665 in repressing the progress of arthritis. Bioengineered 13:5, pages 13328-13340.
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Articles from other publishers (12)

Siyuan Chen, Hui Liu, Yue Wang, Shuyuan Wang, Bo Yang, Di Sun & Pengxiao Sun. (2024) Overexpression of lncRNA LINC00665 inhibits the proliferation and chondroblast differentiation of bone marrow mesenchymal stem cells by targeting miR-214-3p. Journal of Orthopaedic Surgery and Research 19:1.
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Wei He, Zhi-qiang Li, Hou-yun Gu, Qi-lin Pan & Fei-xiang Lin. (2023) Targeted Therapy of Spinal Cord Injury: Inhibition of Apoptosis Is a Promising Therapeutic Strategy. Molecular Neurobiology.
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MinBo Jiang, Yang Li, WenWen Fan, XiaoYan Shen, Kai Jiang & DeGuo Wang. (2023) Circ-KATNAL1 Knockdown Reduces Neuronal Apoptosis and Alleviates Spinal Cord Injury Through the miR-98-5p/PRDM5 Regulatory Axis. Molecular Biotechnology.
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Di Qu, Die Hu, Jing Zhang, Guodong Yang, Jia Guo, Dongfang Zhang, Chao Qi & Haitao Fu. (2023) Identification and Validation of Ferroptosis-Related Genes in Patients with Acute Spinal Cord Injury. Molecular Neurobiology 60:9, pages 5411-5425.
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Yi Ding & Qin Chen. (2023) The NF-κB Pathway: a Focus on Inflammatory Responses in Spinal Cord Injury. Molecular Neurobiology 60:9, pages 5292-5308.
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Yun Li, Niaz Khan, Rodney M. Ritzel, Zhuofan Lei, Samantha Allen, Alan I. Faden & Junfang Wu. (2023) Sexually dimorphic extracellular vesicle responses after chronic spinal cord injury are associated with neuroinflammation and neurodegeneration in the aged brain. Journal of Neuroinflammation 20:1.
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Weiguo Ding, Weixing Xu, Di Lu, Hongfeng Sheng, Xinwei Xu, Bin Xu & Aote Zheng. (2023) Inhibition of TERC inhibits neural apoptosis and inflammation in spinal cord injury through Akt activation and p-38 inhibition via the miR-34a-5p/XBP-1 axis. Open Medicine 18:1.
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Giuseppina Conteduca, Davide Cangelosi, Simona Coco, Michela Malacarne, Chiara Baldo, Alessia Arado, Rute Pinto, Barbara Testa & Domenico A. Coviello. (2022) NSD1 Mutations in Sotos Syndrome Induce Differential Expression of Long Noncoding RNAs, miR646 and Genes Controlling the G2/M Checkpoint. Life 12:7, pages 988.
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Hongjun Liu, Lingjun Qi, Xiaoping Tang, Shasha Tan, Zhangyang Gou, Jian Qi, Xingyu Lu, Dong Li & Chunbao Chen. (2022) Astragalus Polysaccharides Affect Glioblastoma Cells Through Targeting miR-34a-5p. Journal of Biomaterials and Tissue Engineering 12:7, pages 1454-1459.
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Chenming Zhong, Zijun Xie, Jinze Shen, Yunhua Jia & Shiwei Duan. (2022) LINC00665: An Emerging Biomarker for Cancer Diagnostics and Therapeutics. Cells 11:9, pages 1540.
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Linglong Liu, Limei Xu, Shengjie Wang, Lili Wang, Xiaoning Wang, Huifeng Xu, Xihai Li & Hongzhi Ye. (2022) Confirmation of inhibitingTLR4/MyD88/NF-κB Signalling Pathway by Duhuo Jisheng Decoction on Osteoarthritis: A Network Pharmacology Approach-Integrated Experimental Study. Frontiers in Pharmacology 12.
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Zhoujing Yang, Sheng Hu, Yinbin He & Ling Ji. (2021) LINC00665 rescues bupivacaine induced neurotoxicity in human neural cell of SH-SY5Y through has-miR-34a-5p. Brain Research Bulletin 177, pages 210-216.
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