409
Views
67
CrossRef citations to date
0
Altmetric
Original Articles

Quercetin Increased the Antiproliferative Activity of Green Tea Polyphenol (-)-Epigallocatechin Gallate in Prostate Cancer Cells

, &
Pages 580-587 | Received 08 Aug 2011, Accepted 23 Jan 2012, Published online: 27 Mar 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (8)

Hamed Hajipour, Hamed Hamishehkar, Saeed Nazari Soltan Ahmad, Siamak Barghi, Nazila Fathi Maroufi & Ramezan Ali Taheri. (2018) Improved anticancer effects of epigallocatechin gallate using RGD-containing nanostructured lipid carriers. Artificial Cells, Nanomedicine, and Biotechnology 46:sup1, pages 283-292.
Read now
Xiao Zhou, Hong-Yan Liu, Hui Zhao & Tong Wang. (2018) RGD-modified nanoliposomes containing quercetin for lung cancer targeted treatment. OncoTargets and Therapy 11, pages 5397-5405.
Read now
Feng Li, Yongli Wang, Dapeng Li, Yilun Chen, Xuguang Qiao, Rania Fardous, Ashton Lewandowski, Jinbao Liu, Tak-Hang Chan & Q. Ping Dou. (2018) Perspectives on the recent developments with green tea polyphenols in drug discovery. Expert Opinion on Drug Discovery 13:7, pages 643-660.
Read now
Ren-You Gan, Hua-Bin Li, Zhong-Quan Sui & Harold Corke. (2018) Absorption, metabolism, anti-cancer effect and molecular targets of epigallocatechin gallate (EGCG): An updated review. Critical Reviews in Food Science and Nutrition 58:6, pages 924-941.
Read now
Islam Rady, Hadir Mohamed, Mohamad Rady, Imtiaz A. Siddiqui & Hasan Mukhtar. (2018) Cancer preventive and therapeutic effects of EGCG, the major polyphenol in green tea. Egyptian Journal of Basic and Applied Sciences 5:1, pages 1-23.
Read now
Li-Wen Chang, Mei-Ling Hou, Shuo-Hui Hung, Lie-Chwen Lin & Tung-Hu Tsai. (2015) Pharmacokinetics of quercetin-loaded nanodroplets with ultrasound activation and their use for bioimaging. International Journal of Nanomedicine 10, pages 3031-3042.
Read now
Gordana Supic, Maja Jagodic & Zvonko Magic. (2013) Epigenetics: A New Link Between Nutrition and Cancer. Nutrition and Cancer 65:6, pages 781-792.
Read now

Articles from other publishers (59)

Dima Awajan, Anas H. A. Abu-Humaidan & Wamidh H. Talib. (2024) Study of the antitumor activity of the combination baicalin and epigallocatechin gallate in a murine model of vincristine-resistant breast cancer. Pharmacia 71, pages 1-20.
Crossref
Ismail Koyuncu, Ebru Temiz, Fatma Seker, M. Maruf Balos, Feridun Akkafa, Ozgür Yuksekdag, M. Abdullah Yılmaz & Gokhan Zengin. (2024) A mixed‐apoptotic effect of Jurinea mesopotamica extract on prostate cancer cells: a promising source for natural chemotherapeutics . Chemistry & Biodiversity 21:2.
Crossref
Huzaifa Umar, Maryam Rabiu Aliyu, Abdullahi Garba Usman, Umar Muhammad Ghali, Sani Isah Abba & Dilber Uzun Ozsahin. (2023) Prediction of cell migration potential on human breast cancer cells treated with Albizia lebbeck ethanolic extract using extreme machine learning. Scientific Reports 13:1.
Crossref
Miao Hu, Yuyang Huang, Xiaoqian Du, Guannan Liu, Baokun Qi & Yang Li. (2023) The synergistic effect of epigallocatechin-3-gallate and quercetin co-loaded hydrogel beads on inflammatory bowel disease. Food & Function 14:10, pages 4539-4551.
Crossref
Mohammad Imran, Areeba Insaf, Nazeer Hasan, Vrushabh V. Sugandhi, Deumaya Shrestha, Keshav Raj Paudel, Saurav Kumar Jha, Philip M. Hansbro, Kamal Dua, Hari Prasad Devkota & Yousuf Mohammed. (2023) Exploring the Remarkable Chemotherapeutic Potential of Polyphenolic Antioxidants in Battling Various Forms of Cancer. Molecules 28:8, pages 3475.
Crossref
Meng Li, Mengqi Qian, Qian Jiang, Bie Tan, Yulong Yin & Xinyan Han. (2023) Evidence of Flavonoids on Disease Prevention. Antioxidants 12:2, pages 527.
Crossref
Stina George Fernandes, Kavita Gala & Ekta Khattar. (2023) Telomerase inhibitor MST-312 and quercetin synergistically inhibit cancer cell proliferation by promoting DNA damage. Translational Oncology 27, pages 101569.
Crossref
Julio Cesár López-Romero, Heriberto Torres-Moreno, Dora Edith Valencia-Rivera, Mario Alberto Leyva-Peralta, Ramón Efraín Lugo-Sepúlveda, Ramón Enrique Robles-Zepeda, Karen Lillian Rodríguez-Martínez, Mónica Alejandra Villegas-Ochoa, Norma Julieta Salazar-López & Gustavo Adolfo González-Aguilar. (2022) Nueva información del perfil de compuestos bioactivos, potencial antioxidante y antiproliferativo de Parkinsonia praecox (Fabaceae). Acta Botanica Mexicana:129.
Crossref
Joseph Iruthayaraj Ragavan, Ponnusamy M. Anbarasan, Ammasi Arunkumar & A. Ibrahim. (2022) Design, Synthesis, Spectroscopic Characterization, Molecular Docking and Biological Evaluation of 9H-Carbazole Linked 4-Nitrophenol: A DFT Approach. Journal of Computational Biophysics and Chemistry 21:08, pages 909-926.
Crossref
M. Kavimughil, M. Maria Leena, J.A. Moses & C. Anandharamakrishnan. (2022) 3D printed MCT oleogel as a co-delivery carrier for curcumin and resveratrol. Biomaterials 287, pages 121616.
Crossref
Sze Wan Hung, Yiran Li, Xiaoyan Chen, Kai On Chu, Yiwei Zhao, Yingyu Liu, Xi Guo, Gene Chi-Wai Man & Chi Chiu Wang. (2022) Green Tea Epigallocatechin-3-Gallate Regulates Autophagy in Male and Female Reproductive Cancer. Frontiers in Pharmacology 13.
Crossref
Ankit, Rishabha Malviya & Akanksha Sharma. (2022) Sources, Properties, and Pharmacological Effects of Quercetin. Current Nutrition & Food Science 18:5, pages 457-465.
Crossref
Yan Yin, Deming Li, Fang Liu, Xinjing Wang, Yuan Cui, Shilan Li & Xinli Li. (2022) The Ameliorating Effects of Apple Polyphenol Extract on High-Fat-Diet-Induced Hepatic Steatosis Are SIRT1-Dependent: Evidence from Hepatic-Specific SIRT1 Heterozygous Mutant C57BL/6 Mice. Journal of Agricultural and Food Chemistry 70:18, pages 5579-5594.
Crossref
Tae Woo Kim & Hee Gu Lee. (2021) Apigenin Induces Autophagy and Cell Death by Targeting EZH2 under Hypoxia Conditions in Gastric Cancer Cells. International Journal of Molecular Sciences 22:24, pages 13455.
Crossref
Hui Guan, Wenyuan Zhang, Dongxiao Sun-Waterhouse, Yang Jiang, Feng Li, Geoffrey I.N. Waterhouse & Dapeng Li. (2021) Phenolic-protein interactions in foods and post ingestion: Switches empowering health outcomes. Trends in Food Science & Technology 118, pages 71-86.
Crossref
Haoyang Zou, Haiqing Ye, Rajamanikkam Kamaraj, Tiehua Zhang, Jie Zhang & Petr Pavek. (2021) A review on pharmacological activities and synergistic effect of quercetin with small molecule agents. Phytomedicine 92, pages 153736.
Crossref
Abdullah Al Mamun, Anjuman Ara Mimi, Muhammad Zaeem, Yanqing Wu, Ilma Monalisa, Afroza Akter, Fahad Munir & Jian Xiao. (2021) Role of pyroptosis in diabetic retinopathy and its therapeutic implications. European Journal of Pharmacology 904, pages 174166.
Crossref
Soudeh Ghafouri-Fard, Farnaz Aghazadeh Shabestari, Saba Vaezi, Atefe Abak, Hamed Shoorei, Arash Karimi, Mohammad Taheri & Abbas Basiri. (2021) Emerging impact of quercetin in the treatment of prostate cancer. Biomedicine & Pharmacotherapy 138, pages 111548.
Crossref
Suchismita Daw & Sujata Law. (2020) Quercetin induces autophagy in myelodysplastic bone marrow including hematopoietic stem/progenitor compartment. Environmental Toxicology 36:2, pages 149-167.
Crossref
Mei-Lin Chen, Chih-Jen Lai, Yi-Nan Lin, Chien-Ming Huang & Yu-Hsin Lin. (2020) Multifunctional nanoparticles for targeting the tumor microenvironment to improve synergistic drug combinations and cancer treatment effects. Journal of Materials Chemistry B 8:45, pages 10416-10427.
Crossref
Hosam O. Elansary, Agnieszka Szopa, Paweł Kubica, Halina Ekiert, Fahed A. Al-Mana & Mohammed A. Al-Yafrsi. (2020) Antioxidant and Biological Activities of Acacia saligna and Lawsonia inermis Natural Populations. Plants 9:7, pages 908.
Crossref
Julekha Kazi, Ramkrishna Sen, Soumya Ganguly, Tarun Jha, Shantanu Ganguly & Mita Chatterjee Debnath. (2020) Folate decorated epigallocatechin-3-gallate (EGCG) loaded PLGA nanoparticles; in-vitro and in-vivo targeting efficacy against MDA-MB-231 tumor xenograft. International Journal of Pharmaceutics 585, pages 119449.
Crossref
Susanne M. Henning, Piwen Wang, Ru-Po Lee, Amy Trang, George Husari, Jieping Yang, Emma M. Grojean, Austin Ly, Mark Hsu, David Heber, Tristan Grogan, Zhaoping Li & William J. Aronson. (2020) Prospective randomized trial evaluating blood and prostate tissue concentrations of green tea polyphenols and quercetin in men with prostate cancer. Food & Function 11:5, pages 4114-4122.
Crossref
Hosam O. Elansary, Agnieszka Szopa, Paweł Kubica, Halina Ekiert, Diaa O. El-Ansary, Fahed A. Al-Mana & Eman A. Mahmoud. (2020) Polyphenol Content and Biological Activities of Ruta graveolens L. and Artemisia abrotanum L. in Northern Saudi Arabia. Processes 8:5, pages 531.
Crossref
Simona Izzo, Valeria Naponelli & Saverio Bettuzzi. (2020) Flavonoids as Epigenetic Modulators for Prostate Cancer Prevention. Nutrients 12:4, pages 1010.
Crossref
Dalia M. Kopustinskiene, Valdas Jakstas, Arunas Savickas & Jurga Bernatoniene. (2020) Flavonoids as Anticancer Agents. Nutrients 12:2, pages 457.
Crossref
Qiongyu Hao, Tanya Diaz, Alejandro del Rio Verduzco, Clara E. Magyar, Jin Zhong, Yahya Elshimali, Matthew B. Rettig, Susanne M. Henning, Jaydutt V. Vadgama & Piwen Wang. (2020) Arctigenin inhibits prostate tumor growth in high-fat diet fed mice through dual actions on adipose tissue and tumor. Scientific Reports 10:1.
Crossref
Marjorie Reyes-Farias & Catalina Carrasco-Pozo. (2019) The Anti-Cancer Effect of Quercetin: Molecular Implications in Cancer Metabolism. International Journal of Molecular Sciences 20:13, pages 3177.
Crossref
Jesús Santana-Gálvez, Luis Cisneros-Zevallos & Daniel A. Jacobo-Velázquez. (2019) A practical guide for designing effective nutraceutical combinations in the form of foods, beverages, and dietary supplements against chronic degenerative diseases. Trends in Food Science & Technology 88, pages 179-193.
Crossref
Pravien Rajaram, Ziran Jiang, Guanglin Chen, Alyssa Rivera, Alison Phasakda, Qiang Zhang, Shilong Zheng, Guangdi Wang & Qiao-Hong Chen. (2019) Nitrogen-containing derivatives of O-tetramethylquercetin: Synthesis and biological profiles in prostate cancer cell models. Bioorganic Chemistry 87, pages 227-239.
Crossref
Tomoko KAMOHARA, Manami KOSHIGUCHI, Mari MAEDA-YAMAMOTO, Yuki SHINODANorihiro KAMETANIShizuka HIRAI & Yukari EGASHIRA. (2019) The Combination of ‘Benifuuki’ with Quercetin Suppresses Hepatic Fat Accumulation in High-Fat High-Cholesterol Diet-Fed Rats. Journal of Nutritional Science and Vitaminology 65:2, pages 196-201.
Crossref
Murugesan Sathiya Deepika, Ramar Thangam, Thankaraj Salammal Sheena, Rajendran Sasirekha, Srinivasan Sivasubramanian, Manikandan Dinesh Babu, Kulandaivel Jeganathan & Ramasamy Thirumurugan. (2019) A novel rutin-fucoidan complex based phytotherapy for cervical cancer through achieving enhanced bioavailability and cancer cell apoptosis. Biomedicine & Pharmacotherapy 109, pages 1181-1195.
Crossref
Aleksandra Niedzwiecki, Bilwa Bhanap, M. Waheed Roomi & Matthias Rath. 2019. Nutraceuticals in Veterinary Medicine. Nutraceuticals in Veterinary Medicine 611 624 .
Mariam Abotaleb, Samson Samuel, Elizabeth Varghese, Sharon Varghese, Peter Kubatka, Alena Liskova & Dietrich Büsselberg. (2018) Flavonoids in Cancer and Apoptosis. Cancers 11:1, pages 28.
Crossref
Jin-Oh Chung, Seon-Bong Lee, Kang-Hyun Jeong, Ji-Hoon Song, Su-Kyung Kim, Kyung-Mi Joo, Hyun-Woo Jeong, Jin-Kyu Choi, Jeong-Kee Kim, Wan-Gi Kim, Song-Seok Shin & Soon-Mi Shim. (2018) Quercetin and fisetin enhanced the small intestine cellular uptake and plasma levels of epi -catechins in in vitro and in vivo models . Food & Function 9:1, pages 234-242.
Crossref
Gordana Supic, Katarina Zeljic & Zvonko Magic. 2018. Therapeutic Foods. Therapeutic Foods 449 493 .
Ramakumar Tummala, Wei Lou, Allen C. Gao & Nagalakshmi Nadiminty. (2017) Quercetin Targets hnRNPA1 to Overcome Enzalutamide Resistance in Prostate Cancer Cells. Molecular Cancer Therapeutics 16:12, pages 2770-2779.
Crossref
Yan Ding, Kai Ren, Huanhuan Dong, Fei Song, Jing Chen, Youtian Guo, Yanshan Liu, Weijie Tao & Yali Zhang. (2017) Flavonoids from persimmon (Diospyros kaki L.) leaves inhibit proliferation and induce apoptosis in PC-3 cells by activation of oxidative stress and mitochondrial apoptosis. Chemico-Biological Interactions 275, pages 210-217.
Crossref
Piwen Wang, Walter Solorzano, Tanya Diaz, Clara E. Magyar, Susanne M. Henning & Jaydutt V. Vadgama. (2017) Arctigenin inhibits prostate tumor cell growth in vitro and in vivo. Clinical Nutrition Experimental 13, pages 1-11.
Crossref
Kohji Yamaki & Yoko Takahashi. (2017) Additive Beneficial Effect of Epigallocatechin Gallate and Quercetin on the Arteriosclerosis Index in Mice. Food Science and Technology Research 23:2, pages 355-361.
Crossref
Pushpendra Singh, Shashank Kumar & Felix Bast. 2017. Translational Bioinformatics and Its Application. Translational Bioinformatics and Its Application 177 202 .
Piwen Wang, Susanne M. Henning, Clara E. Magyar, Yahya Elshimali, David Heber & Jaydutt V. Vadgama. (2016) Green tea and quercetin sensitize PC-3 xenograft prostate tumors to docetaxel chemotherapy. Journal of Experimental & Clinical Cancer Research 35:1.
Crossref
Aleksandra Niedzwiecki, Mohd Roomi, Tatiana Kalinovsky & Matthias Rath. (2016) Anticancer Efficacy of Polyphenols and Their Combinations. Nutrients 8:9, pages 552.
Crossref
Asha Srinivasan, Chellappagounder Thangavel, Yi Liu, Sunday Shoyele, Robert B. Den, Ponniah Selvakumar & Ashakumary Lakshmikuttyamma. (2016) Quercetin regulates β-catenin signaling and reduces the migration of triple negative breast cancer. Molecular Carcinogenesis 55:5, pages 743-756.
Crossref
Najeeb Ullah, Mahboob Ahmad, Hasnain Aslam, Muhammad Asad Tahir, Muhammad Aftab, Noreen Bibi & Sohail Ahmad. (2016) Green tea phytocompounds as anticancer: A review. Asian Pacific Journal of Tropical Disease 6:4, pages 330-336.
Crossref
Gordana Supic, Darja Wagner & Zvonko Magic. 2016. Critical Dietary Factors in Cancer Chemoprevention. Critical Dietary Factors in Cancer Chemoprevention 153 181 .
Bao Vue, Sheng Zhang & Qiao-Hong Chen. (2015) Synergistic Effects of Dietary Natural Products as Anti-Prostate Cancer Agents. Natural Product Communications 10:12, pages 1934578X1501001.
Crossref
Madhulika Singh & Yogeshwer Shukla. 2015. Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods. Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods 185 217 .
FEIYA YANG, LIMING SONG, HUIPING WANG, JUN WANG, ZHIQING XU & NIANZENG XING. (2015) Quercetin in prostate cancer: Chemotherapeutic and chemopreventive effects, mechanisms and clinical application potential (Review). Oncology Reports 33:6, pages 2659-2668.
Crossref
Feiya Yang, Liming Song, Huiping Wang, Jun Wang, Zhiqing Xu & Nianzeng Xing. (2015) Combination of Quercetin and 2-Methoxyestradiol Enhances Inhibition of Human Prostate Cancer LNCaP and PC-3 Cells Xenograft Tumor Growth. PLOS ONE 10:5, pages e0128277.
Crossref
Massimo Fantini, Monica Benvenuto, Laura Masuelli, Giovanni Frajese, Ilaria Tresoldi, Andrea Modesti & Roberto Bei. (2015) In Vitro and in Vivo Antitumoral Effects of Combinations of Polyphenols, or Polyphenols and Anticancer Drugs: Perspectives on Cancer Treatment. International Journal of Molecular Sciences 16:12, pages 9236-9282.
Crossref
Piwen Wang, Susanne M. Henning, David Heber & Jaydutt V. Vadgama. (2015) Sensitization to docetaxel in prostate cancer cells by green tea and quercetin. The Journal of Nutritional Biochemistry 26:4, pages 408-415.
Crossref
Piwen Wang, Tien Phan, David Gordon, Seyung Chung, Susanne M. Henning & Jaydutt V. Vadgama. (2014) Arctigenin in combination with quercetin synergistically enhances the antiproliferative effect in prostate cancer cells. Molecular Nutrition & Food Research 59:2, pages 250-261.
Crossref
Pushpendra Singh & Felix Bast. (2013) Multitargeted molecular docking study of plant-derived natural products on phosphoinositide-3 kinase pathway components. Medicinal Chemistry Research 23:4, pages 1690-1700.
Crossref
Piwen Wang, Bin Wang, Seyung Chung, Yanyuan Wu, Susanne M. Henning & Jaydutt V. Vadgama. (2014) Increased chemopreventive effect by combining arctigenin, green tea polyphenol and curcumin in prostate and breast cancer cells. RSC Adv. 4:66, pages 35242-35250.
Crossref
Piwen Wang, Jaydutt V. Vadgama, Jonathan W. Said, Clara E. Magyar, Ngan Doan, David Heber & Susanne M. Henning. (2014) Enhanced inhibition of prostate cancer xenograft tumor growth by combining quercetin and green tea. The Journal of Nutritional Biochemistry 25:1, pages 73-80.
Crossref
Cheng Huang, Suz-Yi Lee, Chih-Li Lin, Tzu-Huei Tu, Ling Hsuan Chen, Yi Jing Chen & Hsiu-Chen Huang. (2013) Co-treatment with Quercetin and 1,2,3,4,6-Penta- O -galloyl-β- d -glucose Causes Cell Cycle Arrest and Apoptosis in Human Breast Cancer MDA-MB-231 and AU565 Cells . Journal of Agricultural and Food Chemistry 61:26, pages 6430-6445.
Crossref
Xiaohua Li, Nam Il Park, Yeon Bok Kim, Haeng Hoon Kim, Cheol Ho Park, Qi Wu & Sang Un Park. (2012) Accumulation of flavonoids and expression of flavonoid biosynthetic genes in tartary and rice-tartary buckwheat. Process Biochemistry 47:12, pages 2306-2310.
Crossref
Lalitha Ramachandran, Kanjoormana Aryan Manu, Muthu K. Shanmugam, Feng Li, Kodappully Sivaraman Siveen, Shireen Vali, Shweta Kapoor, Taher Abbasi, Rohit Surana, Duane T. Smoot, Hassan Ashktorab, Patrick Tan, Kwang Seok Ahn, Chun Wei Yap, Alan Prem Kumar & Gautam Sethi. (2012) Isorhamnetin Inhibits Proliferation and Invasion and Induces Apoptosis through the Modulation of Peroxisome Proliferator-activated Receptor γ Activation Pathway in Gastric Cancer. Journal of Biological Chemistry 287:45, pages 38028-38040.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.