Advanced search
Publication Cover
Nutrition and Cancer Volume 68, 2016 - Issue 7
Submit an article Journal homepage
208
Views
20
CrossRef citations to date
0
Altmetric
Original Articles

Sporoderm-Broken Spores of Ganoderma lucidum Inhibit the Growth of Lung Cancer: Involvement of the Akt/mTOR Signaling Pathway

Yali ChenShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China; Pediatric Translational Medicine Institute, Shanghai Children's Medical Center Affiliated to Shanghai Jiao Tong University, Shanghai, China
,
Jing LvShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China
,
Kun LiNational Center for International Research of Biological Targeting Diagnosis and Therapy, Guangxi Medical University, Nanning, China
,
Jing XuZhejiang Rare Herb Medicine Engineering Research Center, Jinhua, Zhejiang, China
,
Mingyan LiShouxiangu Pharmaceutical Company Limited, Jinhua, Zhejiang, China
,
Wen ZhangShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China
&
Xiufeng PangShanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, ChinaCorrespondence[email protected]
 show all
Pages 1151-1160 | Received 22 Nov 2015, Accepted 25 Apr 2016, Published online: 11 Aug 2016

Citations (20)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (3)

Ying Zhou, Minghang Chu, Farhad Ahmadi, Osman Tuncay Agar, Colin J. Barrow, Frank R. Dunshea & Hafiz A.R. Suleria. (2023) A Comprehensive Review on Phytochemical Profiling in Mushrooms: Occurrence, Biological Activities, Applications and Future Prospective. Food Reviews International 0:0, pages 1-28.
Read now
Asem Mahmoud Abdelshafy, Tarun Belwal, Ze Liang, Lei Wang, Dong Li, Zisheng Luo & Li Li. (2022) A comprehensive review on phenolic compounds from edible mushrooms: Occurrence, biological activity, application and future prospective. Critical Reviews in Food Science and Nutrition 62:22, pages 6204-6224.
Read now
Wenkan Zhang, Zhong Lei, Jiahong Meng, Guoqi Li, Yuxiang Zhang, Jiaming He & Weiqi Yan. (2019) Water Extract of Sporoderm-Broken Spores of Ganoderma lucidum Induces Osteosarcoma Apoptosis and Restricts Autophagic Flux. OncoTargets and Therapy 12, pages 11651-11665.
Read now

Articles from other publishers (17)

Lijuan Xia, Ruimin Sun, Liyan Zhang, Jinrong Li, Chengda Zhang, Qian Yang, Lili Zhang, Siming Zhang, Hanbo Wang, Hanying Lyu, Wanqiang Lyu, Zhenhao Li & Lijiang Zhang. (2023) A 26-week repeated dose toxicity evaluation of sporoderm-removed Ganoderma lucidum spores in rats. Food and Chemical Toxicology 182, pages 114175.
Crossref
Nguyen Huu Lac Thuy, Vo Linh Tu, Le Nguyen Anh Thu, Tran Thanh Giang, Dao Tang Khanh Huyen, Duong Hoang Loc, Dao Ngoc Hien Tam, Nguyen Tuan Phat, Hong-Han Huynh, Thien Tan Tri Tai Truyen, Quang-Hien Nguyen, Uyen Do, Dang Nguyen, Truong Van Dat & Le Huu Nhat Minh. (2023) Pharmacological Activities and Safety of Ganoderma lucidum Spores: A Systematic Review. Cureus.
Crossref
Ali Mohammadi, Behzad Mansoori, Elham Safarzadeh, Sahar Gholizadeh & Behzad Baradaran. (2023) Anacyclus pyrethrum extract significantly destroyed lung cancer cell line (A549) by inducing apoptosis. Journal of Herbal Medicine 39, pages 100649.
Crossref
Renald Blundell, Emma Camilleri, Bikash Baral, Tomasz M. Karpiński, Edlira Neza & Omar M. Atrooz. (2023) The Phytochemistry of Ganoderma Species and their Medicinal Potentials . The American Journal of Chinese Medicine 51:04, pages 859-882.
Crossref
M. A. Oke, F. J. Afolabi, O. O. Oyeleke, T. A. Kilani, A. R. Adeosun, A. A. Olanbiwoninu & E. A. Adebayo. (2022) Ganoderma lucidum: Unutilized natural medicine and promising future solution to emerging diseases in Africa. Frontiers in Pharmacology 13.
Crossref
Kaili Cen, Ming Chen, Mengye He, Zhenhao Li, Yinjing Song, Pu Liu, Qi Jiang, Suzhen Xu, Yunlu Jia & Peng Shen. (2022) Sporoderm-Broken Spores of Ganoderma lucidum Sensitizes Ovarian Cancer to Cisplatin by ROS/ERK Signaling and Attenuates Chemotherapy-Related Toxicity. Frontiers in Pharmacology 13.
Crossref
Rizwan Ahmad, Muhammad Riaz, Aslam Khan, Ahmed Aljamea, Mohammad Algheryafi, Deya Sewaket & Aljawharah Alqathama. (2021) Ganoderma lucidum (Reishi) an edible mushroom; a comprehensive and critical review of its nutritional, cosmeceutical, mycochemical, pharmacological, clinical, and toxicological properties . Phytotherapy Research 35:11, pages 6030-6062.
Crossref
Ming Song, Zhen-hao Li, Hong-shun Gu, Ru-ying Tang, Rui Zhang, Ying-li Zhu, Jin-lian Liu, Jian-jun Zhang & Lin-yuan Wang. (2021) Ganoderma lucidum Spore Polysaccharide Inhibits the Growth of Hepatocellular Carcinoma Cells by Altering Macrophage Polarity and Induction of Apoptosis. Journal of Immunology Research 2021, pages 1-14.
Crossref
Guiping Liu & Tao Zeng. (2021) Sporoderm-Removed Ganoderma lucidum Spore Powder May Suppress the Proliferation, Migration, and Invasion of Esophageal Squamous Cell Carcinoma Cells Through PI3K/AKT/mTOR and Erk Pathway . Integrative Cancer Therapies 20, pages 153473542110621.
Crossref
Yunli Yang, Huina Zhang, Jinhui Zuo, Xiaoyan Gong, Fan Yi, Wanshan Zhu & Li Li. (2019) Advances in research on the active constituents and physiological effects of Ganoderma lucidum. Biomedical Dermatology 3:1.
Crossref
Didem Sohretoglu, Chao Zhang, Jun Luo & Shile Huang. (2019) ReishiMax inhibits mTORC1/2 by activating AMPK and inhibiting IGFR/PI3K/Rheb in tumor cells. Signal Transduction and Targeted Therapy 4:1.
Crossref
Yu Sun & Lixin Sun. 2019. Ganoderma and Health. Ganoderma and Health 79 118 .
Paola Rossi, Raffaele Difrancia, Vincenzo Quagliariello, Elena Savino, Paolo Tralongo, Cinzia Lucia Randazzo & Massimiliano Berretta. (2018) B-glucans from Grifola frondosa and Ganoderma lucidum in breast cancer: an example of complementary and integrative medicine. Oncotarget 9:37, pages 24837-24856.
Crossref
Balraj Singh Gill, Navgeet, Richa Mehra, Vicky Kumar & Sanjeev Kumar. (2017) Ganoderic acid, lanostanoid triterpene: a key player in apoptosis. Investigational New Drugs 36:1, pages 136-143.
Crossref
Natalia Nowacka-Jechalke, Marta Olech & Renata Nowak. 2018. Polyphenols: Prevention and Treatment of Human Disease. Polyphenols: Prevention and Treatment of Human Disease 137 150 .
Kang Li, Kun Na, Tingting Sang, Kaikai Wu, Ying Wang & Xingya Wang. (2017) The ethanol extracts of sporoderm-broken spores of Ganoderma lucidum inhibit colorectal cancer in vitro and in vivo. Oncology Reports 38:5, pages 2803-2813.
Crossref
Balraj Singh Gill, Navgeet & Sanjeev Kumar. (2017) Ganoderma lucidum targeting lung cancer signaling: A review . Tumor Biology 39:6, pages 101042831770743.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.