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Inhibitory effects of Nigella sativa and saffron (crocus sativus) on chemical carcinogenesis in mice

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Pages 67-72 | Received 25 Aug 1990, Accepted 31 Dec 1990, Published online: 04 Aug 2009

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Fereshteh Bagheri, Sara Darakhshan, Saharnaz Mazloomi, Behrang Shiri Varnamkhasti & Reza Tahvilian. (2021) Dual loading of Nigella sativa oil-atorvastatin in chitosan–carboxymethyl cellulose nanogel as a transdermal delivery system. Drug Development and Industrial Pharmacy 47:4, pages 569-578.
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Afreen Usmani, Anuradha Mishra, Md Arshad & Asif Jafri. (2019) Development and evaluation of doxorubicin self nanoemulsifying drug delivery system with Nigella Sativa oil against human hepatocellular carcinoma. Artificial Cells, Nanomedicine, and Biotechnology 47:1, pages 933-944.
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Dimitrios Giakoumettis, Chryssa Pourzitaki, Theofanis Vavilis, Anastasia Tsingotjidou, Anastasia Kyriakoudi, Maria Tsimidou, Marina Boziki, Antonia Sioga, Nikolaos Foroglou & Aristeidis Kritis. (2019) Crocus sativus L. Causes a Non Apoptotic Calpain Dependent Death in C6 Rat Glioma Cells, Exhibiting a Synergistic Effect with Temozolomide. Nutrition and Cancer 71:3, pages 491-507.
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Nafise Tabasi, Mahmoud Mahmoudi, Maryam Rastin, Hamid Reza Sadeghnia, Mojtaba HosseinPour Mashhadi, Shahrzad Zamani Taghizade Rabe & Abolfazl Khajavi Rad. (2015) Cytotoxic and apoptogenic properties of Nigella sativa and thymoquinone, its constituent, in human renal cell carcinoma are comparable with cisplatin. Food and Agricultural Immunology 26:1, pages 138-156.
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Zhiyu Zhang, Chong-Zhi Wang, Xiao-Dong Wen, Yukihiro Shoyama & Chun-Su Yuan. (2013) Role of saffron and its constituents on cancer chemoprevention. Pharmaceutical Biology 51:7, pages 920-924.
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Catherine Ulbricht, Julie Conquer, Dawn Costa, Whitney Hollands, Carmen Iannuzzi, Richard Isaac, Joseph K. Jordan, Natalie Ledesma, Cathy Ostroff, Jill M. Grimes Serrano, Michael D. Shaffer & Minney Varghese. (2011) An Evidence-Based Systematic Review of Saffron (Crocus sativus) by the Natural Standard Research Collaboration. Journal of Dietary Supplements 8:1, pages 58-114.
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S. Zahra Bathaie & S. Zeinab Mousavi. (2010) New Applications and Mechanisms of Action of Saffron and its Important Ingredients. Critical Reviews in Food Science and Nutrition 50:8, pages 761-786.
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B.S. Geetha, P.G. Latha & P. Remani. (2010) Evaluation of Elephantopus scaber on the inhibition of chemical carcinogenesis and tumor development in mice. Pharmaceutical Biology 48:3, pages 342-348.
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Elsayed I. Salim & Shoji Fukushima. (2003) Chemopreventive Potential of Volatile Oil From Black Cumin (Nigella sativa L.) Seeds Against Rat Colon Carcinogenesis. Nutrition and Cancer 45:2, pages 195-202.
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K. Premkumar, Suresh K. Abraham, S. T. Santhiya, P. M. Gopinath & A. Ramesh. (2001) INHIBITION OF GENOTOXICITY BY SAFFRON (CROCUS SATIVUS L.) IN MICE. Drug and Chemical Toxicology 24:4, pages 421-428.
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P.G. Latha & K.R. Panikkar. (2000) Inhibition of Chemical Carcinogenesis in Mice by Ixora Coccinea Flowers. Pharmaceutical Biology 38:2, pages 152-156.
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Dolores C. Garc-Olmo, Hans H. Riese, Julio Escribano, Jesús Onta˜´n, José A Fernandez, Manuel Atiénzar & Damiá Garcí-Olmo. (1999) Effects of Long-Term Treatment of Colon Adenocarcinoma With Crocin, a Carotenoid From Saffron (Crocus sativus L.): An Experimental Study in the Rat. Nutrition and Cancer 35:2, pages 120-126.
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S. C. Nair, C D. Varghese, K. R. Paniker, S. K. Kurumboor & R. K. Parathod. (1994) Effects of Saffron on Vitamin A Levels and its Antitumour Activity on the Growth of Solid Tumours in Mice. International Journal of Pharmacognosy 32:2, pages 105-114.
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