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Experimental Lung Research Volume 35, 2009 - Issue 3
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α-PHENYL-N-tert-BUTYLNITRONE ATTENUATES HYPEROXIA-INDUCED LUNG INJURY BY DOWN-MODULATING INFLAMMATION IN NEONATAL RATS

Yun Sil Chang Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea; Samsung Biomedical Research Institute, Seoul, Korea
,
Yu Jin Kim Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
,
Hye Soo Yoo Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
,
Dong Kyung Sung Samsung Biomedical Research Institute, Seoul, Korea
,
Soo Yoon Kim Samsung Biomedical Research Institute, Seoul, Korea
,
Saem Kang Samsung Biomedical Research Institute, Seoul, Korea
&
Won Soon Park Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea; Samsung Biomedical Research Institute, Seoul, KoreaCorrespondence[email protected]
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Pages 234-249 | Received 13 Aug 2008, Accepted 22 Oct 2008, Published online: 02 Jul 2009

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Chiu-wing Lam, Vincent Castranova, Kevin Driscoll, David Warheit, Valerie Ryder, Ye Zhang, Patti Zeidler-Erdely, Robert Hunter, Robert Scully, William Wallace, John James, Brian Crucian, Mayra Nelman, Richard McCluskey, Donald Gardner, Roger Renne & Roger McClellan. (2023) A review of pulmonary neutrophilia and insights into the key role of neutrophils in particle-induced pathogenesis in the lung from animal studies of lunar dusts and other poorly soluble dust particles. Critical Reviews in Toxicology 53:8, pages 441-479.
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Danielle M. Drake, Kian Afsharian, Benjamin Or, Aaron M. Shapiro, Michelle L. Lai, Lutfiya Miller & Peter G. Wells. (2024) BRCA1 protein dose-dependent risk for embryonic oxidative DNA damage, embryopathies and neurodevelopmental disorders with and without ethanol exposure. Redox Biology 70, pages 103070.
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Danielle M. Drake, Danlin Zhen, Isabel Kerrebijn, Benjamin Or, Sophie Gao, Kian Afsharian, Jason Tran, Shama Bhatia, Ashley Cheng & Peter G. Wells. (2023) Breast cancer 1 (BRCA1) protection in altered gene expression and neurodevelopmental disorders due to physiological and ethanol-enhanced reactive oxygen species formation. Free Radical Biology and Medicine 208, pages 272-284.
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Danielle M. Drake & Peter G. Wells. (2021) Novel mechanisms in alcohol neurodevelopmental disorders via BRCA1 depletion and BRCA1-dependent NADPH oxidase regulation. Redox Biology 48, pages 102148.
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Miyeon Kim, Ji Hye Kwon, Yun Kyung Bae, Gee-Hye Kim, Soyoun Um, Jueun Ha, Soo Jin Choi, Wonil Oh & Hye Jin Jin. (2020) Soluble PTX3 of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Attenuates Hyperoxic Lung Injury by Activating Macrophage Polarization in Neonatal Rat Model. Stem Cells International 2020, pages 1-18.
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Ji Hye Kwon, Miyeon Kim, Yun Kyung Bae, Gee-Hye Kim, Soo Jin Choi, Wonil Oh, Soyoun Um & Hye Jin Jin. (2019) Decorin Secreted by Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Induces Macrophage Polarization via CD44 to Repair Hyperoxic Lung Injury. International Journal of Molecular Sciences 20:19, pages 4815.
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Lutfiya Miller-Pinsler, Amy Sharma & Peter G. Wells. (2015) Enhanced NADPH oxidases and reactive oxygen species in the mechanism of methanol-initiated protein oxidation and embryopathies in vivo and in embryo culture. Archives of Toxicology 90:3, pages 717-730.
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So Yoon Ahn, Yun Sil Chang, Dong Kyung Sung, Hye Soo Yoo, Se In Sung, Soo Jin Choi & Won Soon Park. (2015) Cell type–dependent variation in paracrine potency determines therapeutic efficacy against neonatal hyperoxic lung injury. Cytotherapy 17:8, pages 1025-1035.
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Michelle T. Siu, Aaron M. Shapiro, Michael J. Wiley & Peter G. Wells. (2013) A role for glutathione, independent of oxidative stress, in the developmental toxicity of methanol. Toxicology and Applied Pharmacology 273:3, pages 508-515.
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Lutfiya Miller, Aaron M. Shapiro, Jun Cheng & Peter G. Wells. (2013) The free radical spin trapping agent phenylbutylnitrone reduces fetal brain DNA oxidation and postnatal cognitive deficits caused by in utero exposure to a non-structurally teratogenic dose of ethanol: A role for oxidative stress. Free Radical Biology and Medicine 60, pages 223-232.
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Yun Sil Chang, Soo Jin Choi, Dong Kyung Sung, Soo Yoon Kim, Wonil Oh, Yoon Sun Yang & Won Soon Park. (2011) Intratracheal Transplantation of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Dose-Dependently Attenuates Hyperoxia-Induced Lung Injury in Neonatal Rats. Cell Transplantation 20:11-12, pages 1843-1854.
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Ga Won JeonDong Kyung SungYu Jin JungSoo Hyun KooSeo Heui ChoiYun Sil ChangJong Beom SinWon Soon Park. (2011) Granulocyte Colony Stimulating Factor Attenuates Hyperoxia-Induced Lung Injury by Down-Modulating Inflammatory Responses in Neonatal Rats. Yonsei Medical Journal 52:1, pages 65.
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Sarah Mousavi, Mojtaba Mojtahedza & Mohammad Abdollahi. (2010) Place of Iron Chelators Like Desferrioxamine and Deferasirox in Management of Hyperoxia-induced Lung Injury; A Systematic Review. International Journal of Pharmacology 6:4, pages 326-337.
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