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Research Article

Cytochemical and Ultrastructural Changes in the Osteoclast-like Giant Cells of Giant Cell Tumor of Bone Following Bisphosphonate Administration

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Pages 385-391 | Published online: 10 Jul 2009

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Read on this site (4)

Mingmin Shi, Lei Chen, Yangxin Wang, Wei Wang, Yujie Zhang & Shigui Yan. (2019) Effect of bisphosphonates on local recurrence of giant cell tumor of bone: a meta-analysis. Cancer Management and Research 11, pages 669-680.
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Carol P. Y. Lau, Lin Huang, Kwok Chuen Wong & Shekhar Madhukar Kumta. (2013) Comparison of the anti-tumor effects of denosumab and zoledronic acid on the neoplastic stromal cells of giant cell tumor of bone. Connective Tissue Research 54:6, pages 439-449.
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Irene Sulzbacher, Martin Dominkus, Bettina Pichlhofer & Peter R. Mazal. (2009) Expression of platelet-derived growth factor-alpha receptor and c-kit in giant cell tumours of bone. Pathology 41:7, pages 630-633.
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Meera Shreedhara, Andrew Z. Fenves, Diana Benavides & Marvin J. Stone. (2007) Reversibility of Pamidronate-Associated Glomerulosclerosis. Baylor University Medical Center Proceedings 20:3, pages 249-253.
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Articles from other publishers (22)

Marwa Mohsen, Hasnaa Osama, Mina Nicola, Haitham Saeed & Mohamed E. A. Abdelrahim. (2022) Effect of bisphosphonates on bone giant cell tumor recurrence: a meta-analysis. Beni-Suef University Journal of Basic and Applied Sciences 11:1.
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Atrayee Basu Mallick & Sant P. Chawla. (2021) Giant Cell Tumor of Bone: An Update. Current Oncology Reports 23:5.
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Siddharth Dubey, Shishir Rastogi, Venkatesan Sampath, Shah Alam Khan & Arvind Kumar. (2019) Role of intravenous zoledronic acid in management of giant cell tumor of bone- A prospective, randomized, clinical, radiological and electron microscopic analysis. Journal of Clinical Orthopaedics and Trauma 10:6, pages 1021-1026.
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Isao Shibuya, Masamichi Takami, Arei Miyamoto, Akiko Karakawa, Akira Dezawa, Shigeru Nakamura & Ryutaro Kamijo. (2017) In Vitro Study of the Effects of Denosumab on Giant Cell Tumor of Bone: Comparison with Zoledronic Acid. Pathology & Oncology Research 25:1, pages 409-419.
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Zile Singh Kundu, Rajeev Sen, Ankur Dhiman, Pankaj Sharma, Ramchander Siwach & Parveen Rana. (2018) Effect of Intravenous Zoledronic Acid on Histopathology and Recurrence after Extended Curettage in Giant Cell Tumors of Bone: A Comparative Prospective Study. Indian Journal of Orthopaedics 52:1, pages 45-50.
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Shihui Chen, Poying Lau, Ming Lei, Jiang Peng, Tao Tang, Xiaohong Wang, Ling Qin & Shekhar-Madhukar Kumta. (2017) Segmental composite porous scaffolds with either osteogenesis or anti-bone resorption properties tested in a rabbit ulna defect model. Journal of Tissue Engineering and Regenerative Medicine 11:1, pages 34-43.
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Raphaële Charest-Morin, Stefano Boriani, Charles G. Fisher, Shreyaskumar R. Patel, Norio Kawahara, Ehud Mendel, Chetan Bettegowda & Laurence D. Rhines. (2016) Benign Tumors of the Spine. Spine 41:20, pages S178-S185.
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Thomas Brodowicz, Margit Hemetsberger & Reinhard Windhager. (2015) Denosumab for the treatment of giant cell tumor of the bone. Future Oncology 11:13, pages 1881-1894.
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Omar Kujan, Ahmad Zahi Al-Shawaf, Saleh Azzeghaiby, Ahmad AlManadille, Kusay Aziz & Syed Ahmed Raheel. (2015) Immunohistochemical Comparison of p53, Ki-67, CD68, Vimentin, α-smooth Muscle Actin and Alpha-1-Antichymotrypsin in Oral Peripheral and Central Giant Cell Granuloma. The Journal of Contemporary Dental Practice 16:1, pages 20-24.
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Tobias A. Mattei, Edwin Ramos, Azeem A. Rehman, Andrew Shaw, Shreyasumar R. Patel & Ehud Mendel. (2014) Sustained long-term complete regression of a giant cell tumor of the spine after treatment with denosumab. The Spine Journal 14:7, pages e15-e21.
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Yilin Zhang, Weiqiang Yu, Xinquan Jiang, Kaige Lv, Shengjun Sun & Fuqiang Zhang. (2011) Analysis of the cytotoxicity of differentially sized titanium dioxide nanoparticles in murine MC3T3-E1 preosteoblasts. Journal of Materials Science: Materials in Medicine 22:8, pages 1933-1945.
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Carol P.Y. Lau, Lin Huang, Stephen K.W. Tsui, Patrick K.S. Ng, Pui-Yin. Leung & Shekhar M. Kumta. (2011) Pamidronate, farnesyl transferase, and geranylgeranyl transferase-I inhibitors affects cell proliferation, apoptosis, and OPG/RANKL mRNA expression in stromal cells of giant cell tumor of bone. Journal of Orthopaedic Research 29:3, pages 403-413.
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Maurice Balke, Laura Campanacci, Carsten Gebert, Piero Picci, Max Gibbons, Richard Taylor, Pancras Hogendoorn, Judith Kroep, John Wass & Nicholas Athanasou. (2010) Bisphosphonate treatment of aggressive primary, recurrent and metastatic Giant Cell Tumour of Bone. BMC Cancer 10:1.
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Sheila Conway Adams, Benjamin K. Potter, Philip G. Robinson & H. Thomas Temple. (2010) Giant Cell Tumor of the Distal Femur Associated with Complete Tumor Necrosis. Orthopedics 33:9.
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Jiao Sun & Tingting Ding. (2008) p53 reaction to apoptosis induced by hydroxyapatite nanoparticles in rat macrophages. Journal of Biomedical Materials Research Part A 88A:3, pages 673-679.
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Lung Fung Tse, Kwok Chuen Wong, Shekhar Madhukar Kumta, Lin Huang, Tsun Cheung Chow & James Francis Griffith. (2008) Bisphosphonates reduce local recurrence in extremity giant cell tumor of bone: A case–control study. Bone 42:1, pages 68-73.
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Jesse T. Torbert, Harish S. Hosalkar, Kingsley R. Chin, Edward J. Fox, Carol A. Dolinskas, Richard Daniels & Richard D. Lackman. 2008. Interventional Spine. Interventional Spine 453 467 .
Mathias Werner. (2006) Giant cell tumour of bone: morphological, biological and histogenetical aspects. International Orthopaedics 30:6, pages 484-489.
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Alpdogan Kantarci, Hatice Hasturk & Thomas E. Dyke. (2006) Host-mediated resolution of inflammation in periodontal diseases. Periodontology 2000 40:1, pages 144-163.
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Robert E. Turcotte. (2006) Giant Cell Tumor of Bone. Orthopedic Clinics of North America 37:1, pages 35-51.
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Evandro Neves Abdo, Luiz César Fonseca Alves, Alessandra Sabrina Rodrigues, Ricardo Alves Mesquita & Ricardo Santiago Gomez. (2005) Treatment of a central giant cell granuloma with intralesional corticosteroid. British Journal of Oral and Maxillofacial Surgery 43:1, pages 74-76.
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Y. Y. Cheng, L. Huang, K. M. Lee, J. K. Xu, M. H. Zheng & S. M. Kumta. (2004) Bisphosphonates Induce Apoptosis of Stromal Tumor Cells in Giant Cell Tumor of Bone. Calcified Tissue International 75:1, pages 71-77.
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