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Food Additives & Contaminants Volume 23, 2006 - Issue 11
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Original Articles

Determination of genotoxic phenylhydrazine agaritine in mushrooms using liquid chromatography–electrospray ionization tandem mass spectrometry

Kazunari Kondo National Institute of Health Sciences, Division of Foods, Kamiyoga 1-18-1, Setagaya, Tokyo 158-8501, JapanCorrespondence[email protected]
,
Asako Watanabe National Institute of Health Sciences, Division of Foods, Kamiyoga 1-18-1, Setagaya, Tokyo 158-8501, Japan
,
Yuko Iwanaga National Institute of Health Sciences, Division of Foods, Kamiyoga 1-18-1, Setagaya, Tokyo 158-8501, Japan
,
Ikuro Abe University of Shizuoka, School of Pharmaceutical Sciences, Yada 52-1, Suruga-ku, Shizuoka 422-8526, Japan
,
Hideya Tanaka University of Shizuoka, School of Pharmaceutical Sciences, Yada 52-1, Suruga-ku, Shizuoka 422-8526, Japan
,
Megumi Hamano Nagaoka National Institute of Health Sciences, Division of Foods, Kamiyoga 1-18-1, Setagaya, Tokyo 158-8501, Japan
,
Hiroshi Akiyama National Institute of Health Sciences, Division of Foods, Kamiyoga 1-18-1, Setagaya, Tokyo 158-8501, Japan
&
Tamio Maitani National Institute of Health Sciences, Division of Foods, Kamiyoga 1-18-1, Setagaya, Tokyo 158-8501, Japan
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Pages 1179-1186 | Received 30 Nov 2005, Accepted 15 May 2006, Published online: 11 Feb 2011

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Yiğitcan Sümbelli, Rüstem Keçili, Deniz Hür, Arzu Ersöz & Rıdvan Say. (2021) Molecularly imprinted polymer embedded-cryogels as selective genotoxic impurity scavengers. Separation Science and Technology 56:18, pages 3066-3078.
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Articles from other publishers (13)

Hari Naga Prasada Reddy Chittireddy, J. V. Shanmukha Kumar, Anuradha Bhimireddy, Mohammed Rafi Shaik, Mujeeb Khan, Merajuddin Khan, Tae Hwan Oh & Baji Shaik. (2023) Development and Validation of Analytical Method Using Gas Chromatography with Triple Quadrupole Mass Spectrometry for the Detection of Alkyl Halides as Potential Genotoxic Impurities in Posaconazole. Separations 10:5, pages 295.
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Hari Naga Prasada Reddy Chittireddy, J. V. Shanmukha Kumar, Anuradha Bhimireddy, Mohammed Rafi Shaik, Mohammad Rafe Hatshan, Mujeeb Khan, Abdulrahman Alwarthan & Baji Shaik. (2023) Development and Validation for Quantitative Determination of Genotoxic Impurity in Gemfibrozil by Gas Chromatography with Mass Spectrometry. Separations 10:3, pages 145.
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Murat Soyseven, Rüstem Keçili, Hassan Y Aboul-Enein & Göksel Arli. (2021) Determination of Potential Genotoxic Impurity, 5-Amino-2-Chloropyridine, in Active Pharmaceutical Ingredient Using the HPLC-UV System. Journal of Chromatographic Science 59:3, pages 241-245.
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Rüstem Keçili, Ecevit Yılmaz, Arzu Ersöz & Rıdvan Say. 2020. Sustainable Nanoscale Engineering. Sustainable Nanoscale Engineering 317 350 .
Raquel Viveiros, Maria Inês Lopes, William Heggie & Teresa Casimiro. (2017) Green approach on the development of lock-and-key polymers for API purification. Chemical Engineering Journal 308, pages 229-239.
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Ambavaram Vijaya Bhaskar Reddy, Jafariah Jaafar, Khalid Umar, Zaiton Abdul Majid, Azmi Bin Aris, Juhaizah Talib & Gajulapalle Madhavi. (2015) Identification, control strategies, and analytical approaches for the determination of potential genotoxic impurities in pharmaceuticals: A comprehensive review. Journal of Separation Science 38:5, pages 764-779.
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Rustem Kecili, Johan Billing, David Nivhede, Börje Sellergren, Anthony Rees & Ecevit Yilmaz. (2014) Fast identification of selective resins for removal of genotoxic aminopyridine impurities via screening of molecularly imprinted polymer libraries. Journal of Chromatography A 1339, pages 65-72.
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Achille Cappiello, Giorgio Famiglini, Pierangela Palma, Veronica Termopoli & Helga Trufelli. (2012) A new liquid chromatography–mass spectrometry approach for generic screening and quantitation of potential genotoxic alkylation compounds without derivatization. Journal of Chromatography A 1255, pages 286-290.
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Rustem Kecili, David Nivhede, Johan Billing, Mats Leeman, Börje Sellergren & Ecevit Yilmaz. (2012) Removal of Acrolein from Active Pharmaceutical Ingredients Using Aldehyde Scavengers. Organic Process Research & Development 16:6, pages 1225-1229.
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Antonio Giordani, Werner Kobel & Hans Ulrich Gally. (2011) Overall impact of the regulatory requirements for genotoxic impurities on the drug development process. European Journal of Pharmaceutical Sciences 43:1-2, pages 1-15.
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David Q. Liu, Mingjiang Sun & Alireza S. Kord. (2010) Recent advances in trace analysis of pharmaceutical genotoxic impurities. Journal of Pharmaceutical and Biomedical Analysis 51:5, pages 999-1014.
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Kazunari Kondo, Asako Watanabe, Hiroshi Akiyama & Tamio Maitani. (2008) The metabolisms of agaritine, a mushroom hydrazine in mice. Food and Chemical Toxicology 46:3, pages 854-862.
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. (2007) Current literature in mass spectrometry. Journal of Mass Spectrometry 42:6, pages 830-841.
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