312
Views
51
CrossRef citations to date
0
Altmetric
Original Articles

Deoxynivalenol: Rationale for development and application of a urinary biomarker

, , , , &
Pages 864-871 | Received 05 Oct 2007, Accepted 19 Dec 2007, Published online: 19 Jun 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (8)

Larissa Tuanny Franco, Amir Ismail, Adnan Amjad & Carlos Augusto Fernandes de Oliveira. (2021) Occurrence of toxigenic fungi and mycotoxins in workplaces and human biomonitoring of mycotoxins in exposed workers: a systematic review. Toxin Reviews 40:4, pages 576-591.
Read now
Larissa Tuanny Franco, Amin Mousavi Khaneghah, Sarah Hwa In Lee & Carlos Augusto Fernandes Oliveira. (2021) Biomonitoring of mycotoxin exposure using urinary biomarker approaches: a review. Toxin Reviews 40:4, pages 383-403.
Read now
Maria Papageorgiou, Liz Wells, Courtney Williams, Kay L.M. White, Barbara De Santis, Yunru Liu, Francesca Debegnach, Brunella Miano, Giorgio Moretti, Stephanie Greetham, Carlo Brera, Stephen L. Atkin, Laura J. Hardie & Thozhukat Sathyapalan. (2018) Occurrence of deoxynivalenol in an elderly cohort in the UK: a biomonitoring approach. Food Additives & Contaminants: Part A 35:10, pages 2032-2044.
Read now
Ulrike Brezina, Inga Rempe, Susanne Kersten, Hana Valenta, Hans-Ulrich Humpf & Sven Dänicke. (2014) Diagnosis of intoxications of piglets fed with Fusarium toxin-contaminated maize by the analysis of mycotoxin residues in serum, liquor and urine with LC-MS/MS. Archives of Animal Nutrition 68:6, pages 425-447.
Read now
Silvia W. Gratz, Anthony J. Richardson, Gary Duncan & Grietje Holtrop. (2014) Annual variation of dietary deoxynivalenol exposure during years of different Fusarium prevalence: a pilot biomonitoring study. Food Additives & Contaminants: Part A 31:9, pages 1579-1585.
Read now
S. Piekkola, P.C. Turner, M. Abdel-Hamid, S. Ezzat, M. El-Daly, S. El-Kafrawy, E. Savchenko, T. Poussa, J.C.S. Woo, H. Mykkänen & H. El-Nezami. (2012) Characterisation of aflatoxin and deoxynivalenol exposure among pregnant Egyptian women. Food Additives & Contaminants: Part A 29:6, pages 962-971.
Read now
Paul C. Turner, Kay L.M. White, Victoria J. Burley, Richard P. Hopton, Anita Rajendram, Julie Fisher, Janet E. Cade & Christopher P. Wild. (2010) A comparison of deoxynivalenol intake and urinary deoxynivalenol in UK adults. Biomarkers 15:6, pages 553-562.
Read now
R.P. Hopton, E. Turner, V.J. Burley, P.C. Turner & J. Fisher. (2010) Urine metabolite analysis as a function of deoxynivalenol exposure: an NMR-based metabolomics investigation. Food Additives & Contaminants: Part A 27:2, pages 255-261.
Read now

Articles from other publishers (43)

Tianqi Tan, Tingting Chen, Wenwen Zhu, Lin Gong, Yizhong Yan, Qian Li, Li Chen, Yiling Li, Jialin Liu, Yanan Li, Xuefeng Yang, Liping Hao, Huaiji Wang, Nianhong Yang & Sheng Wei. (2023) Adverse associations between maternal deoxynivalenol exposure and birth outcomes: a prospective cohort study in China. BMC Medicine 21:1.
Crossref
Gunnar Sundstøl Eriksen, Helle K. Knutsen, Morten Sandvik & Anne-Lise Brantsæter. (2021) Urinary deoxynivalenol as a biomarker of exposure in different age, life stage and dietary practice population groups. Environment International 157, pages 106804.
Crossref
Paul C. Turner & Jessica A. Snyder. (2021) Development and Limitations of Exposure Biomarkers to Dietary Contaminants Mycotoxins. Toxins 13:5, pages 314.
Crossref
Ying Deng, Li You, Eugenie Nepovimova, Xu Wang, Kamil Musilek, Qinghua Wu, Wenda Wu & Kamil Kuca. (2021) Biomarkers of deoxynivalenol (DON) and its modified form DON-3-glucoside (DON-3G) in humans. Trends in Food Science & Technology 110, pages 551-558.
Crossref
Farhad Niknejad, Laura Escrivá, Khoda Berdi Adel Rad, Masoud Khoshnia, Francisco J. Barba & Houda Berrada. (2021) Biomonitoring of Multiple Mycotoxins in Urine by GC–MS/MS: A Pilot Study on Patients with Esophageal Cancer in Golestan Province, Northeastern Iran. Toxins 13:4, pages 243.
Crossref
Ruqin Lin, Yu Sun, Peiqiang Mu, Ting Zheng, Haibin Mu, Fengru Deng, Yiqun Deng & Jikai Wen. (2020) Lactobacillus rhamnosus GG supplementation modulates the gut microbiota to promote butyrate production, protecting against deoxynivalenol exposure in nude mice. Biochemical Pharmacology 175, pages 113868.
Crossref
Silvia W. Gratz, Valerie CurrieGary DuncanDiane Jackson. (2019) Multimycotoxin Exposure Assessment in UK Children Using Urinary Biomarkers—A Pilot Survey. Journal of Agricultural and Food Chemistry 68:1, pages 351-357.
Crossref
Amin Mousavi Khaneghah, Yadolah Fakhri, Hadi Hashemi Gahruie, Mehrdad Niakousari & Anderson S. Sant’Ana. (2019) Mycotoxins in cereal-based products during 24 years (1983–2017): A global systematic review. Trends in Food Science & Technology 91, pages 95-105.
Crossref
De Santis, Debegnach, Miano, Moretti, Sonego, Chiaretti, Buonsenso & Brera. (2019) Determination of Deoxynivalenol Biomarkers in Italian Urine Samples. Toxins 11:8, pages 441.
Crossref
Irina Slobodchikova, Reajean Sivakumar, Md Samiur Rahman & Dajana Vuckovic. (2019) Characterization of Phase I and Glucuronide Phase II Metabolites of 17 Mycotoxins Using Liquid Chromatography—High-Resolution Mass Spectrometry. Toxins 11:8, pages 433.
Crossref
Xiaodan Wang, Jiang Liang, Pei Cao, Shuang Zhou, Aibo Wu, Peng Gao, Haibin Xu, Zhaoping Liu & Yunyun Gong. (2019) Biomonitoring Study of Deoxynivalenol Exposure in Chinese Inhabitants. International Journal of Environmental Research and Public Health 16:12, pages 2169.
Crossref
Bingxuan Jia, Song Yu, Qinghua Wu & Aibo Wu. 2019. Food Safety & Mycotoxins. Food Safety & Mycotoxins 79 100 .
Sonia Marín, German Cano-Sancho, Vicente Sanchis & Antonio J. Ramos. (2018) The role of mycotoxins in the human exposome: Application of mycotoxin biomarkers in exposome-health studies. Food and Chemical Toxicology 121, pages 504-518.
Crossref
Cécile Vignal, Madjid Djouina, Muriel Pichavant, Ségolène Caboche, Christophe Waxin, Delphine Beury, David Hot, Corinne Gower-Rousseau & Mathilde Body-Malapel. (2018) Chronic ingestion of deoxynivalenol at human dietary levels impairs intestinal homeostasis and gut microbiota in mice. Archives of Toxicology 92:7, pages 2327-2338.
Crossref
Arnau Vidal, Liesel Claeys, Marcel Mengelers, Valérie Vanhoorne, Chris Vervaet, Bart Huybrechts, Sarah De Saeger & Marthe De Boevre. (2018) Humans significantly metabolize and excrete the mycotoxin deoxynivalenol and its modified form deoxynivalenol-3-glucoside within 24 hours. Scientific Reports 8:1.
Crossref
Maria Papageorgiou, Liz Wells, Courtney Williams, Kay White, Barbara De Santis, Yunru Liu, Francesca Debegnach, Brunella Miano, Giorgio Moretti, Stephanie Greetham, Carlo Brera, Stephen Atkin, Laura Hardie & Thozhukat Sathyapalan. (2018) Assessment of Urinary Deoxynivalenol Biomarkers in UK Children and Adolescents. Toxins 10:2, pages 50.
Crossref
Linghong Jin, Wei Wang, Jeroen Degroote, Noémie Van Noten, Honglin Yan, Maryam Majdeddin, Mario Van Poucke, Luc Peelman, Anne Goderis, Kurt Van De Mierop, Ronny Mombaerts, Stefaan De Smet & Joris Michiels. (2017) Mycotoxin binder improves growth rate in piglets associated with reduction of toll-like receptor-4 and increase of tight junction protein gene expression in gut mucosa. Journal of Animal Science and Biotechnology 8:1.
Crossref
Liz Wells, Laura Hardie, Courtney Williams, Kay White, Yunru Liu, Barbara De Santis, Francesca Debegnach, Georgio Moretti, Stephanie Greetham, Carlo Brera, Maria Papageorgiou, Natalie Thatcher, Alan Rigby, Stephen Atkin & Thozhukat Sathyapalan. (2017) Deoxynivalenol Biomarkers in the Urine of UK Vegetarians. Toxins 9:7, pages 196.
Crossref
Delphine Payros, Ulrich Dobrindt, Patricia Martin, Thomas Secher, Ana Paula F. L. Bracarense, Michèle Boury, Joelle Laffitte, Philippe Pinton, Eric Oswald & Isabelle P. Oswald. (2017) The Food Contaminant Deoxynivalenol Exacerbates the Genotoxicity of Gut Microbiota. mBio 8:2.
Crossref
Liz Wells, Laura Hardie, Courtney Williams, Kay White, Yunru Liu, Barbara De Santis, Francesca Debegnach, Georgio Moretti, Stephanie Greetham, Carlo Brera, Alan Rigby, Stephen Atkin & Thozhukat Sathyapalan. (2016) Determination of Deoxynivalenol in the Urine of Pregnant Women in the UK. Toxins 8:11, pages 306.
Crossref
Hyun Jung LeeDojin Ryu. (2015) Advances in Mycotoxin Research: Public Health Perspectives. Journal of Food Science 80:12, pages T2970-T2983.
Crossref
Carlo Brera, Barbara de Santis, Francesca Debegnach, Brunella Miano, Giorgio Moretti, Antonio Lanzone, Gelsomina Del Sordo, Danilo Buonsenso, Antonio Chiaretti, Laura Hardie, Kay White, Anne Lise Brantsæter, Helle Knutsen, Gunnar Sundstøl Eriksen, Morten Sandvik, Liz Wells, Stephanie Allenf & Thozhukat Sathyapalanf. (2015) Experimental study of deoxynivalenol biomarkers in urine. EFSA Supporting Publications 12:6.
Crossref
Catherine Tardivel, Coraline Airault, Mehdi Djelloul, Florent Guillebaud, Rym Barbouche, Jean-Denis Troadec, Stéphanie Gaigé & Michel Dallaporta. (2015) The food born mycotoxin deoxynivalenol induces low-grade inflammation in mice in the absence of observed-adverse effects. Toxicology Letters 232:3, pages 601-611.
Crossref
Ulrike Brezina, Hana Valenta, Inga Rempe, Susanne Kersten, Hans-Ulrich Humpf & Sven Dänicke. (2014) Development of a liquid chromatography tandem mass spectrometry method for the simultaneous determination of zearalenone, deoxynivalenol and their metabolites in pig serum. Mycotoxin Research 30:3, pages 171-186.
Crossref
Yuseok Moon & Dongwook Kim. (2014) Human and Animal Disease Biomarkers and Biomonitoring of Deoxynivalenol and Related Fungal Metabolites as Cereal and Feed Contaminants. Journal of Food Hygiene and Safety 29:2, pages 85-91.
Crossref
Manuel J. Saint-Cyr, Agnès Perrin-Guyomard, Paméla Houée, Jean-Guy Rolland & Michel Laurentie. (2013) Evaluation of an Oral Subchronic Exposure of Deoxynivalenol on the Composition of Human Gut Microbiota in a Model of Human Microbiota-Associated Rats. PLoS ONE 8:11, pages e80578.
Crossref
M. Solfrizzo, L. Gambacorta, B. Warth, K. White, C. Srey, M. Sulyok, R. Krska & Y.Y. Gong. (2013) Comparison of single and multi-analyte methods based on LC-MS/MS for mycotoxin biomarker determination in human urine. World Mycotoxin Journal 6:4, pages 355-366.
Crossref
Brenna M. Flannery, Chidozie J. Amuzie & James J. Pestka. (2013) Evaluation of insulin-like growth factor acid-labile subunit as a potential biomarker of effect for deoxynivalenol-induced proinflammatory cytokine expression. Toxicology 304, pages 192-198.
Crossref
J.D. Groopman, T.W. Kensler & F. Wu. 2013. Encyclopedia of Human Nutrition. Encyclopedia of Human Nutrition 337 341 .
Paul Craig Turner & Barbara Zappe Pasturel. 2013. Risk Assessment and Evaluation of Predictions. Risk Assessment and Evaluation of Predictions 333 347 .
Emmanuel Njumbe Ediage, Jose Diana Di Mavungu, Suquan Song, Aibo Wu, Carlos Van Peteghem & Sarah De Saeger. (2012) A direct assessment of mycotoxin biomarkers in human urine samples by liquid chromatography tandem mass spectrometry. Analytica Chimica Acta 741, pages 58-69.
Crossref
Paul C. Turner, Brenna Flannery, Catherine Isitt, Mariyam Ali & James Pestka. (2012) The role of biomarkers in evaluating human health concerns from fungal contaminants in food. Nutrition Research Reviews 25:1, pages 162-179.
Crossref
Michele Solfrizzo, Lucia Gambacorta, Veronica M. T. Lattanzio, Stephen Powers & Angelo Visconti. (2011) Simultaneous LC–MS/MS determination of aflatoxin M1, ochratoxin A, deoxynivalenol, de-epoxydeoxynivalenol, α and β-zearalenols and fumonisin B1 in urine as a multi-biomarker method to assess exposure to mycotoxins. Analytical and Bioanalytical Chemistry 401:9, pages 2831-2841.
Crossref
Jeanette K.S. Nielsen, Anna C. Vikström, Paul Turner & Lisbeth E. Knudsen. (2011) Deoxynivalenol transport across the human placental barrier. Food and Chemical Toxicology 49:9, pages 2046-2052.
Crossref
André Nogueira da Costa, Jeffrey N. Keen, Christopher P. Wild & John B.C. Findlay. (2011) An analysis of the phosphoproteome of immune cell lines exposed to the immunomodulatory mycotoxin deoxynivalenol. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1814:7, pages 850-857.
Crossref
André Nogueira da Costa, Renée S. Mijal, Jeffrey N. Keen, John B. C. Findlay & Christopher P. Wild. (2011) Proteomic analysis of the effects of the immunomodulatory mycotoxin deoxynivalenol. PROTEOMICS 11:10, pages 1903-1914.
Crossref
Gordon Shephard. (2011) Fusarium mycotoxins and human health. Plant Breeding and Seed Science 64:1, pages 113-121.
Crossref
James J. Pestka. (2010) Deoxynivalenol-Induced Proinflammatory Gene Expression: Mechanisms and Pathological Sequelae. Toxins 2:6, pages 1300-1317.
Crossref
Paul C. Turner, Richard P. Hopton, Yannick Lecluse, Kay L. M. White, Julie Fisher & Pierre Lebailly. (2010) Determinants of Urinary Deoxynivalenol and De-epoxy Deoxynivalenol in Male Farmers from Normandy, France. Journal of Agricultural and Food Chemistry 58:8, pages 5206-5212.
Crossref
G. Shephard, F. Berthiller, J. Dorner, R. Krska, G. Lombaert, B. Malone, C. Maragos, M. Sabino, M. Solfrizzo, M. Trucksess, H. van Egmond & T. Whitaker. (2010) Developments in mycotoxin analysis: an update for 2008-2009. World Mycotoxin Journal 3:1, pages 3-23.
Crossref
Chidozie J. Amuzie & James J. Pestka. (2010) Suppression of Insulin-Like Growth Factor Acid-Labile Subunit Expression—A Novel Mechanism for Deoxynivalenol-Induced Growth Retardation. Toxicological Sciences 113:2, pages 412-421.
Crossref
S. Duarte, J. Bento, A. Pena, C.M. Lino, C. Delerue-Matos, T. Oliva-Teles, S. Morais, M. Correia, M.B.P.P. Oliveira, M.R. Alves & J.A. Pereira. (2010) Monitoring of ochratoxin A exposure of the Portuguese population through a nationwide urine survey — Winter 2007. Science of The Total Environment 408:5, pages 1195-1198.
Crossref
Kai Bester, Christa S. McArdell, Cajsa Wahlberg & Thomas D. Bucheli. 2010. Xenobiotics in the Urban Water Cycle. Xenobiotics in the Urban Water Cycle 3 26 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.