312
Views
51
CrossRef citations to date
0
Altmetric
Original Articles

Deoxynivalenol: Rationale for development and application of a urinary biomarker

, , , , &
Pages 864-871 | Received 05 Oct 2007, Accepted 19 Dec 2007, Published online: 19 Jun 2008

References

  • Bhat , RV , Beedu , SR , Ramakrishna , Y and Munshi , KL . 1989 . Outbreak of trichothecenes mycotoxicosis associated with consumption of mould-damaged wheat production in Kashmir Valley, India . Lancet , 1 : 35 – 37 .
  • Bondy , GS and Pestka , JJ . 2000 . Immunomodulation by fungal toxins . J Toxicol Environ Health B Crit Rev , 3 : 109 – 143 .
  • Canady , RA , Coker , RD , Egan , SK , Krska , R , Kuiper-Goodman , T , Olsen , M , Pestka , J , Resnik , S and Schlatter , J . 2001 . Deoxynivalenol , 420 – 529 . Geneva : Safety evaluation of certain mycotoxins in food. . World Health Organization
  • CAST Potential economic costs of mycotoxins in the United States . 2003 . Mycotoxins: Risks in plant, animal, and human systems , Task Force Report No. 139 136 – 142 . Ames IA : Council for Agriculture, Science and Technology .
  • Cote , LM , Dahlem , AM , Yoshizawa , T , Swanson , SP and Buck , WB . 1986 . Excretion of deoxynivalenol and its metabolite in milk, urine, and feces of lactating dairy cows . J Dairy Sci , 69 : 2416 – 2423 .
  • Creppy , EE . 2002 . Update of survey, regulation and toxic effects of mycotoxins in Europe . Toxicol Lett , 127 : 19 – 28 .
  • Cirilloy , T , Ritieniy , A , Galvanoz , F and Amodio-Cocchieriy , R . 2003 . Natural co-occurrence of deoxynivalenol and fumonisins B1 and B2 in Italian marketed foodstuffs . Food Addit Contam , 20 : 566 – 571 .
  • Gong , Y , Torres-Sanchez , L , Lopez-Carrillo , L , Peng , JH , Sutcliffe , AE , White , KLM , Turner , PC , Humpf , H and Wild , CP . 2008 . Detection of fumonisin B1 in Mexican urine samples using liquid chromatography-mass spectrometry: A possible biomarker of dietary fumonisin exposure . Cancer Epidemiol Biomarkers Prev ,
  • Goyarts , T and Danicke , S . 2006 . Bioavailability of the Fusarium toxin deoxynivalenol (DON) from naturally contaminated wheat for the pig . Toxicol Lett , 163 : 171 – 182 .
  • Goyarts , T , Danicke , S , Rothkotter , HJ , Spilke , J , Tiemann , U and Schllenberger , M . 2005 . On the effects of a chronic deoxynivalenol intoxication on performance, haematological and serum parameters of pigs when diets are offered either for ad libitum consumption or fed restrictively . J Vet Med A Physiol Pathol Clin Med , 52 : 305 – 314 .
  • Gray , JS and Pestka , JJ . 2007 . Transcriptional regulation of deoxynivalenol-induced IL-8 expression in human monocytes . Toxicol Sci , 99 : 502 – 511 .
  • Groopman , JD , Jackson , PE , Turner , PC , Wild , CP and Kensler , TW . 2002 . “ Validation of exposure and risk biomarkers: aflatoxin as a case study ” . In Biomarkers of environmentally associated disease , Edited by: Wilson , SH and Suk , WA . 307 – 318 . Boca Raton, FL : CRC Press. .
  • Groopman JD. Johnson , D and Kensler , T . 2005 . Aflatoxin and hepatitis B virus biomarkers: A paradigm for complex environmental exposures and cancer risk . Cancer Biomarkers , 1 : 5 – 14 .
  • Henderson , L , Gregory , J and Swan , G . 2002 . The National Diet and Nutrition Survey: adults aged 19 to 64 years , HMSO : Norwich . Available: http://www.food.gov.uk/multimedia/pdfs/ndnsprintedreport.pdf. Accessed: 5 October 2007
  • Jackson , LS and Bullerman , LB . 1999 . Effect of processing on Fusarium mycotoxins . Adv Exp Med Biol , 459 : 243 – 261 .
  • Jelinek , CF , Pohland , AE and Wood , GE . 1989 . Worldwide occurrence of mycotoxins in foods and feeds. An update . J Assoc Off Anal Chem , 72 : 223 – 230 .
  • Lattanzio , VM , Solfrizzo , M , Powers , S and Visconti , A . 2007a . Simultaneous determination of aflatoxins, ochratoxin A and Fusarium toxins in maize by liquid chromatography/tandem mass spectrometry after multitoxin immunoaffinity cleanup . Rapid Commun Mass Spectrom , 21 : 3253 – 3261 .
  • Lattanzio , VM , Solfrizzo , M and Visconti , A . 2007b . Determination of trichothecenes in cereals and cereal-based products by liquid chromatography–tandem mass spectrometry . Food Addit Contam , In press (Epublished ahead of print)
  • Li , F , Luo , X and Yoshizawa , T . 1999 . Mycotoxins (trichothecenes, zearalenone and fumonisins) in cereals associated with human red mold intoxications stored since 1989 and 1991 in China . Nat Toxins , 7 : 93 – 97 .
  • Luo , X . 1994 . Food poisoning caused by Fusarium toxins , 129 – 136 . Proceedings of the 2nd Asian Conference on Food Safety .
  • Luo , Y , Yoshizawa , T and Katayama , T . 1990 . Comparative study on the natural occurrence of Fusarium mycotoxins (trichothecenes and zearalenone) in corn and wheat from high- and low-risk areas for human esophageal cancer in China . Appl Environ Microbiol , 56 : 3723 – 3726 .
  • Meky , FA , Hardie , LJ , Evans , SW and Wild , CP . 2001 . Deoxynivalenol-induced immunomodulation of human lymphocyte proliferation and cytokine production . Food Chem Toxicol , 39 : 827 – 836 .
  • Meky , FA , Turner , PC , Ashcroft , AE , Miller , JD , Qiao , Y-L , Roth , MJ and Wild , CP . 2003 . Development of a urinary biomarker of human exposure to deoxynivalenol . Food Chem Toxicol , 41 : 265 – 273 .
  • Miller , JD . 1995 . Fungi and mycotoxins in grain: Implications for stored product research . J Stored Prod Res , 31 : 1 – 16 .
  • Montesano , R , Hainaut , P and Wild , CP . 1997 . Hepatocellular carcinoma: From gene to public health . J Natl Cancer Inst , 89 : 1844 – 1851 .
  • Office for National Statistics . 2005 . “ Social and Vital Statistics Division and Food Standards Agency ” . In National Diet and Nutrition Survey: Adults Aged 19 to 64 Years , Colchester : UK Data Archive . Essex SN: 5140 2000–2001
  • Pestka , JJ . 2003 . Deoxynivalenol-induced IgA production and IgA nephropathy-aberrant mucosal immune response with systemic repercussions . Toxicol Lett , 140–141 : 287 – 95 .
  • Pestka , JJ and Smolinski , AT . 2005 . Deoxynivalenol: Toxicology and potential effects on humans . J Toxicol Environ Health B Crit Rev , 8 : 39 – 69 .
  • Pestka , JJ , Zhou , HR , Moon , Y and Chung , YJ . 2004 . Cellular and molecular mechanisms for immune modulation by deoxynivalenol and other trichothecenes: Unraveling a paradox . Toxicol Lett , 153 : 61 – 73 .
  • Prelusky , DB . 1997 . Effect of intraperitoneal infusion of deoxynivalenol on feed consumption and weight gain in the pig . Nat Toxins , 5 : 121 – 125 .
  • Prelusky , DB , Trenholm , HL , Lawrence , GA and Scott , PM . 1984 . Nontransmission of deoxynivalenol (vomitoxin) to milk following oral administration to dairy cows . J Environ Sci Health B , 19 : 593 – 609 .
  • Prelusky , DB , Veira , DM , Trenholm , HL and Hartin , KE . 1986 . Excretion profiles of the mycotoxin deoxynivalenol, following oral and intravenous administration to sheep . Fundam Appl Toxicol , 6 : 356 – 363 .
  • Prelusky , DB , Hartin , KE , Trenholm , HL and Miller , JD . 1988 . Pharmacokinetic fate of 14C-labeled deoxynivalenol in swine . Fundam Appl Toxicol , 10 : 276 – 286 .
  • Rotter , BA , Prelusky , DB and Pestka , JJ . 1996 . Toxicology of deoxynivalenol (vomitoxin) . J Toxicol Environ Health , 48 : 1 – 34 .
  • SCF Opinion of the Scientific Committee on Food on Fusarium toxins. Part 6 . 2002 . Group evaluation of T-2 toxin, HT-2 toxin, nivalenol and deoxynivalenol: SCF/CS/CNTM/MYC/27 Final , Available: http://europa.eu.int/comm/food/fs/sc/scf/out123_en.pdf. Accessed: 5 October 2007
  • Schlatter , J . 2004 . Toxicity data relevant for hazard characterization . Toxicol Lett , 153 : 83 – 9 .
  • SCOOP . 2003 . Collection of occurrence data of Fusarium toxins in food and assessment of dietary intake by the population of EU member states . SCOOP Task 3.2.10 Final Report , Available: http://europa.eu.int/comm/food/fs/scoop/task3210.pdf. Accessed: 5 October 2007
  • Speijers , GJA and Speijers , MHM . 2004 . Combined toxic effects of mycotoxins . Toxicol Lett , 153 : 91 – 8 .
  • Sundstol-Eriksen , G and Pettersson , H . 2003 . Lack of de-epoxidation of type B trichothecenes in incubates with human faeces . Food Addit Contam , 20 : 579 – 582 .
  • Sugita-Konishi , Y , Park , BJ , Kobayashi-Hattori , K , Tanaka , T , Chonan , T , Yoshikawa , K and Kumagai , S . 2006 . Effect of cooking process on the deoxynivalenol content and its subsequent cytotoxicity in wheat products . Biosci Biotechnol Biochem , 70 : 1764 – 1768 .
  • Tiemann , U , Bruusow , KP , Jonas , L , Pohland , R , Schneider , F and Danicke , S . 2006 . Effects of diets with cereal grains contaminated by graded levels of two Fusarium toxins on selected immunological and histological measurements in the spleen of gilts . J Anim Sci , 84 : 236 – 245 .
  • Turner , PC , Nikiema , P and Wild , CP . 1999 . Fumonisin Contamination of food: Progress in development of biomarkers to better assess human health . Mutat Res , 443 : 81 – 93 .
  • Turner , PC , Burley , VJ , Rothwell , JA , White , KLM , Cade , JE and Wild , CP . 2007 . Dietary wheat reduction decreases the level of urinary deoxynivalenol in UK adults . J Expos Sci Environ Epidemiol , (Epub on line doi:10.1038/sj.jes.7500611)
  • Turner , PC , Rothwell , JA , White , KLM , Cade , JE and Wild , CP . 2008 . Cereal intake is correlated with urinary deoxynivalenol in individuals from the UK . Environ Health Perspect , 36 : 1119 – 1125 .
  • WHO . 1990 . “ Selected Mycotoxins ” . In Ochratoxin, Tricothecenes, Ergot , Environmental Health Criteria No. 105 Geneva : WHO .
  • Wild , CP and Turner , PC . 2001 . “ Exposure biomarkers in chemoprevention studies of liver cancer ” . In Biomarkers in cancer chemoprevention. IARC Scientific Publications No.154 , Edited by: Miller , AB , Bartsch , H , Bofetta , P , Dragsted , L and Vanio , H . 215 – 222 . Lyon, , France : International Agency for Research on Cancer .
  • Wild , CP and Turner , PC . 2002 . The toxicology of aflatoxins as a basis for public health decisions . Mutagenesis , 17 : 471 – 481 .
  • Wild , CP , Andersson , C , O’Brian , NM , Wilson , L and Woods , JA . 2001 . A critical evaluation of the application of biomarkers in epidemiological studies on diet and health . Br J Nutr , 86 ( Suppl 1 ) : S37 – S53 .
  • Wild , CP , Hudson , GJ , Sabbioni , G , Chapot , B , Hall , AJ , Wogan , GN , Whittle , H , Montesano , R and Groopman , JD . 1992 . Dietary intake of aflatoxins and the level of albumin-bound aflatoxin in peripheral blood in The Gambia, West Africa . Cancer Epidemiol Biomarkers Prev , 1 : 229 – 234 .
  • Yoshizawa , T , Cote , LM , Swanson , SP and Buck , WB . 1986 . Confirmation of DOM-1, a de-epoxidation metabolite of deoxynivalenol in biological fluids of lactating cows . Agric Biol Chem , 50 : 227 – 229 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.