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Original Articles

Residues of the beta‐agonist clenbuterol in tissues of medicated farm animals

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Pages 231-244 | Received 21 Aug 1992, Published online: 10 Jan 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (11)

Chi-Fang Peng, Zhi-Feng Qin, Zhou-Xi Ruan, Chuan-Lai Xu & Zheng-Yu Jin. (2011) Rapid Determination of Clenbuterol in Urine by a Competitive Bead Immunoassay Based on Luminex Technology. Immunological Investigations 40:1, pages 14-28.
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P. González-Gigosos, C. Fente-Sampay, C. Franco-Abuín, A. Cepeda-Sáez & B. I. Vázquez-Belda. (2002) Effects of frozen storage on the recovery of clenbuterol from urine samples for official control. Food Additives & Contaminants 19:11, pages 1010-1014.
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Thomas Y. K. Chan. (2001) Food-Borne Clenbuterol May Have Potential for Cardiovascular Effects with Chronic Exposure (Commentary). Journal of Toxicology: Clinical Toxicology 39:4, pages 345-348.
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Laura Cerni, Giancarlo Biancotto, Adriana Tondolo & Paolo Bogoni. (1998) Dexamethasone and clenbuterol detection by enzyme immunoassay in Bovine Liver Tissue: A new multiresidue extraction procedure. Food and Agricultural Immunology 10:4, pages 307-315.
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E. S. Rodgers, C. T. Elliott, A. Li Wan Po, D. P. Mackie, E. M. Scott & J. Kreuter. (1997) The potential of polymeric nanoparticles to increase the immunogenicity of the hapten clenbuterol. Food and Agricultural Immunology 9:3, pages 159-166.
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ChristopherT. Elliott, Andrew Baxter, Willem Haasnoot, Arjen Lommen & William J. McCaughey. (1996) Development of a dual label time‐resolved fluoroimmunoassay for the detection of (β‐agonists in cattle urine. Food and Agricultural Immunology 8:4, pages 219-227.
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C.T. Elliott, H.D. Shortt, D.G. Kennedy & W.J. McCaughey. (1996) Monitoring for clenbuterol abuse in N. Ireland 1989–1994. Veterinary Quarterly 18:2, pages 41-44.
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Eleonora Petruzzelli, Adriano Ius, Silvia Berta, Mauro Dovis & Alberto Albertini. (1996) Preparation and characterization of a monoclonal antibody specific for the β‐agonist clenbuterol. Food and Agricultural Immunology 8:1, pages 3-10.
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C.T. Elliott, W.J. McCaughey, S.R.H. Crooks, J.D.G. McEvoy & D.G. Kennedy. (1995) Residues of clenbuterol in cattle receiving therapeutic doses: Implications for differentiating between legal and illegal use. Veterinary Quarterly 17:3, pages 100-102.
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Articles from other publishers (37)

Michael D. Roberts, John J. McCarthy, Troy A. Hornberger, Stuart M. Phillips, Abigail L. Mackey, Gustavo A. Nader, Marni D. Boppart, Andreas N. Kavazis, Paul T. Reidy, Riki Ogasawara, Cleiton A. Libardi, Carlos Ugrinowitsch, Frank W. Booth & Karyn A. Esser. (2023) Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions. Physiological Reviews 103:4, pages 2679-2757.
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Xinyue Wang & Yang Liu. 2023. Aptamers for Food Applications. Aptamers for Food Applications 213 226 .
Libin Wan, Haidong Gao, Xiao Liu, Shucai Gao, Li Zhou, Fayun Wang & Mantang Chen. (2022) Electromembrane extraction of clenbuterol from swine urine for monitoring illegal use in livestock. Journal of Separation Science 45:21, pages 3966-3973.
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Li Tian, Kexin Wu, Yue Hu, Yue Wang, Yingjie Zhao, Ruizhan Chen & Juan Lu. (2020) A molecularly imprinted electrochemiluminescence nanoprobe based on complexes consisting of CdTe and multiwall carbon nanotube for sensitive determination of clenbuterol. Microchimica Acta 187:6.
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Yuan Chen, Zhen Huang, Song Hu, Ganggang Zhang, Juan Peng, Jun Xia & Weihua Lai. (2019) Integrated immunochromatographic assay for qualitative and quantitative detection of clenbuterol. Analytical Biochemistry 577, pages 45-51.
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Jia Liu, Chaohua Tang, Ruijun Long, Kai Zhang, Yunsheng Han, Qingyu Zhao, Hongliang Wang, Fuzhong Zhao, Qingshi Meng & Junmin Zhang. (2019) The use of hair as a long‐term indicator of low‐dose β 2 agonist treatments in cattle: Implications for growth‐promoting purposes monitoring . Drug Testing and Analysis 11:6, pages 745-751.
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Dulal C. Kabiraz, Kinichi Morita, Kazuhira Sakamoto, Masashi Takahashi & Toshikazu Kawaguchi. (2018) Highly sensitive detection of clenbuterol in urine sample by using surface plasmon resonance immunosensor. Talanta 186, pages 521-526.
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Yujuan Yang, Xu Gu, Yingchao Dong, Junguo Li, Haiqiu Ni, Moyong Xue, Zhen Zhao, Zhiwei Sun & Yuchang Qin. (2018) Determination of Salbutamol Residues in Goat Various Tissues After Exposure to Growth-promoting Doses. Journal of Analytical Toxicology 42:1, pages 55-62.
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Jingyun Wang, Lei Zhang, Youju Huang, Anirban Dandapat, Liwei Dai, Ganggang Zhang, Xuefei Lu, Jiawei Zhang, Weihua Lai & Tao Chen. (2017) Hollow Au-Ag Nanoparticles Labeled Immunochromatography Strip for Highly Sensitive Detection of Clenbuterol. Scientific Reports 7:1.
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Zhihong Zhang, Fenghe Duan, Linghao He, Donglai Peng, Fufeng Yan, Minghua Wang, Wei Zong & Chunxiao Jia. (2016) Electrochemical clenbuterol immunosensor based on a gold electrode modified with zinc sulfide quantum dots and polyaniline. Microchimica Acta 183:3, pages 1089-1097.
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Jingyan Kang, Yujie Zhang, Xing Li, Lijing Miao & Aiguo Wu. (2015) A Rapid Colorimetric Sensor of Clenbuterol Based on Cysteamine-Modified Gold Nanoparticles. ACS Applied Materials & Interfaces 8:1, pages 1-5.
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Jelka Pleadin, Ana Vulić, Svjetlana Terzić, Nada Vahčić, Ksenija Šandor & Eleonora Perak. (2014) Comparison of Accumulation of Clenbuterol and Salbutamol Residues in Animal Internal Tissues, Non-Pigmented Eyes and Hair. Journal of Analytical Toxicology 38:9, pages 681-685.
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Qiangqiang Fu, Jiajie Liang, Caifeng Lan, Kenan Zhou, Congying Shi & Yong Tang. (2014) Development of a novel dual-functional lateral-flow sensor for on-site detection of small molecule analytes. Sensors and Actuators B: Chemical 203, pages 683-689.
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J. Pleadin, A. Vulic, N. Persi, S. Terzic, M. Andrisic & I. Zarkovic. (2013) Rapid Immunoassay Method for the Determination of Clenbuterol and Salbutamol in Blood. Journal of Analytical Toxicology 37:4, pages 241-245.
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Shengxi Li, Jiong Zhang, Wangping Deng, Xizhong Shen, Shiping Song & Chunhai Fan. (2012) A Highly Sensitive Amperometric Immunosensor for Clenbuterol Detection in Livestock Urine. Electroanalysis 25:4, pages 867-873.
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?? ?. (2013) Research on Concentration of Clenbuterol in the Pig Urine at Different Storage Conditions. Hans Journal of Food and Nutrition Science 02:03, pages 43-47.
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Ana Gonz?lez-Antu?a, Iv?n Lavandera, Pablo Rodr?guez-Gonz?lez, Julio Rodr?guez, Jos? Ignacio Garc?a Alonso & Vicente Gotor. (2011) A straightforward route to obtain 13C1-labeled clenbuterol. Tetrahedron 67:31, pages 5577-5581.
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Jelka Pleadin, Ana Vulić, Nina Perši & Nada Vahčić. (2010) Clenbuterol residues in pig muscle after repeat administration in a growth-promoting dose. Meat Science 86:3, pages 733-737.
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Jelka Pleadin, Tihomira Gojmerac, Zoran Lipej, Mario Mitak, Dinko Novosel & Nina Per?i. (2009) Accumulation of the ?2-adrenergic agonist clenbuterol in mouse dark hair. Archives of Toxicology 83:11, pages 979-983.
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Jiaming Liu, Liqing Zeng, Zhiming Li, Fei Gao, Xiaomei Huang, Feiming Li & Huiqing Lin. (2009) Solid substrate-room temperature phosphorimetry for the determination of residual clenbuterol hydrochloride based on the catalysis of sodium periodate oxidizing eosine Y. Analytica Chimica Acta 638:1, pages 69-74.
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Tihomira Gojmerac, Jelka Pleadin, Igor Bratoš, Ana Vulić & Nada Vahčić. (2008) Xenobiotic clenbuterol in food producing male pigs: Various tissue residue accumulation on days after withdrawal. Meat Science 80:3, pages 879-884.
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Colin S. Thompson, Simon A. Haughey, Imelda M. Traynor, Terence L. Fodey, Christopher T. Elliott, Jean-Philippe Antignac, Bruno Le Bizec & Steven R.H. Crooks. (2008) Effective monitoring for ractopamine residues in samples of animal origin by SPR biosensor and mass spectrometry. Analytica Chimica Acta 608:2, pages 217-225.
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Jieyu Zhou, Xueshu Xu & Yuxiao Wang. (2007) Competitive immunoassay for clenbuterol using capillary electrophoresis with laser-induced fluorescence detection. Journal of Chromatography B 848:2, pages 226-231.
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Sophie Danyi, Guy Degand, Colette Duez, Benoît Granier, Guy Maghuin-Rogister & Marie-Louise Scippo. (2007) Solubilisation and binding characteristics of a recombinant β2-adrenergic receptor expressed in the membrane of Escherichia coli for the multianalyte detection of β-agonists and antagonists residues in food-producing animals. Analytica Chimica Acta 589:2, pages 159-165.
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G.P. Zhang, X.N. Wang, J.F. Yang, Y.Y. Yang, G.X. Xing, Q.M. Li, D. Zhao, S.J. Chai & J.Q. Guo. (2006) Development of an immunochromatographic lateral flow test strip for detection of β-adrenergic agonist Clenbuterol residues. Journal of Immunological Methods 312:1-2, pages 27-33.
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Marie Annette Johansson & Karl‐Erik Hellenäs. (2004) Immunobiosensor determination of β ‐agonists in urine using integrated immunofiltration clean‐up . International Journal of Food Science & Technology 39:8, pages 891-898.
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L. R. Soma, C. E. Uboh, F. Guan, Y. Luo, D. Teleis, L. Runbo, E. K. Birks, D. S. Tsang & P. Habecker. (2004) Tissue distribution of clenbuterol in the horse. Journal of Veterinary Pharmacology and Therapeutics 27:2, pages 91-98.
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Imad K. Abukhalaf, Daniel A. von Deutsch, Bryan A. Parks, Larry Wineski, Douglas Paulsen, Hassan Y. Aboul-Enein & David E. Potter. (2000) Comparative analytical quantitation of clenbuterol in biological matrices using GC-MS and EIA. Biomedical Chromatography 14:2, pages 99-105.
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Adriano Podestà, Alberto Luppi, Leonardo Benatti, Chiara Villani, Giorgio Montagnoli & Franco Martelli. (1998) A source of false-negative results in clenbuterol analysis in tissues of veal calves. Journal of Pharmacological and Toxicological Methods 40:1, pages 27-32.
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Jenny Cai & Jack Henion. (1997) Quantitative multi-residue determination of β-agonists in bovine urine using on-line immunoaffinity extraction-coupled column packed capillary liquid chromatography-tandem mass spectrometry. Journal of Chromatography B: Biomedical Sciences and Applications 691:2, pages 357-370.
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S.R.H. Crooks, C.T. Elliott, C.S. Thompson & W.J. McCaughey. (1997) Comparison and evaluation of the specificity and binding capacity of commercial and in house affinity columns used in sample preparation for analysis of growth-promoting drugs. Journal of Chromatography B: Biomedical Sciences and Applications 690:1-2, pages 161-172.
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Timothy Wachs, Robin L. Sheppard & Jack Henion. (1996) Design and applications of a self-aligning liquid junction-electrospray interface for capillary electrophoresis-mass spectrometry. Journal of Chromatography B: Biomedical Sciences and Applications 685:2, pages 335-342.
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Peter Batjoens, Dirk Courtheyn, Hubert F. De Brabander, Jan Vercammen, Katia De Wasch & Maureen Logghe. (1996) Gas chromatographic-tandem mass spectrometric analysis of clenbuterol residues in faeces. Journal of Chromatography A 750:1-2, pages 133-139.
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Damien Boyd, Michael O'Keeffe & Malcolm R. Smyth. (1996) Methods for the determination of β-agonists in biological matrices. A review. The Analyst 121:1, pages 1R-10R.
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M.J. SAUER, R.J.H. PICKETT, S. LIMER & S.N. DIXON. (2008) Distribution and elimination of clenbuterol in tissues and fluids of calves following prolonged oral administration at a growth‐promoting dose. Journal of Veterinary Pharmacology and Therapeutics 18:2, pages 81-86.
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B. Biolatti, E. Bollo, G. Re, S. Appino, E. Tartari, G. Benatti, C.T. Elliott & W.J. McCaughey. (1994) Pathology and residues in veal calves treated experimentally with clenbuterol. Research in Veterinary Science 57:3, pages 365-371.
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C. T. Elliott, S. R. H. Crooks, J. G. D. McEvoy, W. J. McCaughey, S. A. Hewitt, D. Patterson & D. Kilpatrick. (1993) Observations on the effects of long-term withdrawal on carcass composition and residue concentrations in clenbuterol-medicated cattle. Veterinary Research Communications 17:6, pages 459-468.
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