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Research Article

The in-vitro and in-vivo characterization of PLGA:L-PLA microspheres containing dexamethasone sodium phosphate

Pages 603-612 | Published online: 29 Sep 2008

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Kai Dong, Hefeng Zhang, Yan Yan, Jinyao Sun, Yalin Dong, Ke Wang, Lu Zhang, Xianpeng Shi & Jianfeng Xing. (2017) Improvement of side-effects and treatment on the experimental colitis in mice of a resin microcapsule-loading hydrocortisone sodium succinate. Drug Development and Industrial Pharmacy 43:3, pages 448-457.
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Aiguo Zeng, Kai Dong, Maoling Wang, Jinyao Sun, Yalin Dong, Ke Wang, Chenning Guo, Yan Yan, Lu Zhang, Xianpeng Shi & Jianfeng Xing. (2016) Investigation of the colon-targeting, improvement on the side-effects and therapy on the experimental colitis in mouse of a resin microcapsule loading dexamethasone sodium phosphate. Drug Delivery 23:6, pages 1992-2002.
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Saowanee Jaraswekin, Sompol Prakongpan & Roland Bodmeier. (2007) Effect of poly(lactide-co-glycolide) molecular weight on the release of dexamethasone sodium phosphate from microparticles. Journal of Microencapsulation 24:2, pages 117-128.
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İ. Yeni˙ce, S. Çaliş, B. Ati˙lla, H. S. Kaş, M. Özalp, M. Eki˙zoğlu, H. Bi˙lgi˙li˙ & A. A. Hincal. (2003) in vitro/in vivo evaluation of the efficiency of teicoplanin-loaded biodegradable microparticles formulated for implantation to infected bone defects. Journal of Microencapsulation 20:6, pages 705-717.
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C. S. Chaw, Y. Y. Yang, I. J. Lim & T. T. Phan. (2003) Water-soluble betamethasone-loaded poly(lactide-co-glycolide) hollow microparticles as a sustained release dosage form. Journal of Microencapsulation 20:3, pages 349-359.
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Articles from other publishers (26)

Chenghao Zhang & Roland Bodmeier. (2023) Direct drug milling in organic PLGA solution facilitates the encapsulation of nanosized drug into PLGA microparticles. European Journal of Pharmaceutics and Biopharmaceutics 191, pages 1-11.
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Samet Özdemir, Burcu Üner, Juste Baranauskaite, Engin Sümer, Ecem Yıldırım & Aylin Yaba. (2023) Design and characterization of dexamethasone loaded microsponges for the management of ulcerative colitis. European Journal of Pharmaceutics and Biopharmaceutics 187, pages 34-45.
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Mohamed S. El-khooly. 2023. Updates on Corticosteroids [Working Title]. Updates on Corticosteroids [Working Title].
Yating Gong, Muyao Wu, Fan Gao, Mengying Shi, Haiping Gu, Rong Gao, Bao-Qi Dang & Gang Chen. (2021) Inhibition of the p‑SPAK/p‑NKCC1 signaling pathway protects the blood‑brain barrier and reduces neuronal apoptosis in a rat model of surgical brain injury. Molecular Medicine Reports 24:4.
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Ahmed Saber Abd Raboh, Mohammed Salah El-khooly & Mohammed Yousry Hassaan. (2021) Bioactivity and Drug Release Study of Dexamethasone Loaded Bioglass/Chitosan Composites for Biomedical Applications. Journal of Inorganic and Organometallic Polymers and Materials 31:7, pages 2779-2790.
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Xing Li, Lu Xu, Hemin Nie & Lei Lei. (2020) Dexamethasone‐loaded β‐cyclodextrin for osteogenic induction of mesenchymal stem/progenitor cells and bone regeneration. Journal of Biomedical Materials Research Part A 109:7, pages 1125-1135.
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Scott P. Nichols, Ahyeon Koh, Wesley L. Storm, Jae Ho Shin & Mark H. Schoenfisch. (2013) Biocompatible Materials for Continuous Glucose Monitoring Devices. Chemical Reviews 113:4, pages 2528-2549.
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Parawee Rattanakit, Simon E. Moulton, Karen S. Santiago, Saisunee Liawruangrath & Gordon G. Wallace. (2012) Extrusion printed polymer structures: A facile and versatile approach to tailored drug delivery platforms. International Journal of Pharmaceutics 422:1-2, pages 254-263.
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Youdan Wang, Xinsheng Gao, Satish Kuriyavar, David Bourne, Brian Grady, Kejian Chen, Kenneth Dormer & Richard D. Kopke. (2011) Incorporation, Release, and Effectiveness of Dexamethasone in Poly(Lactic-Co-Glycolic Acid) Nanoparticles for Inner Ear Drug Delivery. Journal of Nanotechnology in Engineering and Medicine 2:1.
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Albino Martins, Ana Rita C. Duarte, Susana Faria, Alexandra P. Marques, Rui L. Reis & Nuno M. Neves. (2010) Osteogenic induction of hBMSCs by electrospun scaffolds with dexamethasone release functionality. Biomaterials 31:22, pages 5875-5885.
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Chunyan Wang, Alireza Javadi, Mehdi Ghaffari & Shaoqin Gong. (2010) A pH-sensitive molecularly imprinted nanospheres/hydrogel composite as a coating for implantable biosensors. Biomaterials 31:18, pages 4944-4951.
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Upkar Bhardwaj & Diane J. Burgess. (2010) Physicochemical properties of extruded and non-extruded liposomes containing the hydrophobic drug dexamethasone. International Journal of Pharmaceutics 388:1-2, pages 181-189.
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Omer Faruk Turkoglu, Hakan Eroglu, Ozerk Okutan, Oktay Gurcan, Ebru Bodur, Mustafa F. Sargon, Levent Öner & Etem Beskonaklı. (2009) Atorvastatin efficiency after traumatic brain injury in rats. Surgical Neurology 72:2, pages 146-152.
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Ana Rita C. Duarte, João F. Mano & Rui L. Reis. (2009) Dexamethasone-loaded scaffolds prepared by supercritical-assisted phase inversion. Acta Biomaterialia 5:6, pages 2054-2062.
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Yogesh Patil & Jayanth Panyam. (2009) Polymeric nanoparticles for siRNA delivery and gene silencing. International Journal of Pharmaceutics 367:1-2, pages 195-203.
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Ana Rita C. Duarte, João F. Mano & Rui L. Reis. (2009) Preparation of chitosan scaffolds loaded with dexamethasone for tissue engineering applications using supercritical fluid technology. European Polymer Journal 45:1, pages 141-148.
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Tze-Wen Chung, Shoei-Shen Wang, Yen-Zen Wang, Chien-Hung Hsieh & Earl Fu. (2008) Enhancing growth and proliferation of human gingival fibroblasts on chitosan grafted poly (ε-caprolactone) films is influenced by nano-roughness chitosan surfaces. Journal of Materials Science: Materials in Medicine 20:1, pages 397-404.
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Mahesh D. Chavanpatil, Ayman Khdair, Yogesh Patil, Hitesh Handa, Guangzhao Mao & Jayanth Panyam. (2007) Polymer‐surfactant nanoparticles for sustained release of water‐soluble drugs. Journal of Pharmaceutical Sciences 96:12, pages 3379-3389.
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Susan S. D'Souza & Patrick P. DeLuca. (2006) Methods to Assess in Vitro Drug Release from Injectable Polymeric Particulate Systems. Pharmaceutical Research 23:3, pages 460-474.
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Tze-Wen Chung, Yen-Zen Wang, Yi-You Huang, Chin-I Pan & Shoei-Shen Wang. (2006) Poly (e-caprolactone) Grafted With Nano-structured Chitosan Enhances Growth of Human Dermal Fibroblasts. Artificial Organs 30:1, pages 35-41.
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L.W. Norton, E. Tegnell, S.S. Toporek & W.M. Reichert. (2005) In vitro characterization of vascular endothelial growth factor and dexamethasone releasing hydrogels for implantable probe coatings. Biomaterials 26:16, pages 3285-3297.
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S. Freiberg & X.X. Zhu. (2004) Polymer microspheres for controlled drug release. International Journal of Pharmaceutics 282:1-2, pages 1-18.
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Amy C. Richards Grayson, Michael J. Cima & Robert Langer. (2004) Molecular release from a polymeric microreservoir device: Influence of chemistry, polymer swelling, and loading on device performance. Journal of Biomedical Materials Research 69A:3, pages 502-512.
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H. Süheyla Kaş. 2004. Biomaterials. Biomaterials 221 230 .
Jun Jin Yoon, Jung Hoe Kim & Tae Gwan Park. (2003) Dexamethasone-releasing biodegradable polymer scaffolds fabricated by a gas-foaming/salt-leaching method. Biomaterials 24:13, pages 2323-2329.
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Jonathan A. Friedman, Anthony J. Windebank, Michael J. Moore, Robert J. Spinner, Bradford L. Currier & Michael J. Yaszemski. (2002) Biodegradable Polymer Grafts for Surgical Repair of the Injured Spinal Cord. Neurosurgery 51:3, pages 742-752.
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