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Original

Microspheres with pH modulated release: Design and characterization of formulation variables for colonic delivery

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Pages 420-431 | Received 07 Feb 2008, Accepted 21 Aug 2008, Published online: 17 Jul 2009

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Read on this site (6)

Enas El-Maghawry, Mina I Tadros, Seham A Elkheshen & Ahmed Abd-Elbary. (2020) Eudragit®-S100 Coated PLGA Nanoparticles for Colon Targeting of Etoricoxib: Optimization and Pharmacokinetic Assessments in Healthy Human Volunteers. International Journal of Nanomedicine 15, pages 3965-3980.
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Hong Zhou & Haixin Qian. (2018) Preparation and characterization of pH-sensitive nanoparticles of budesonide for the treatment of ulcerative colitis. Drug Design, Development and Therapy 12, pages 2601-2609.
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Amit Arya, Dipak K. Majumdar, Dharam Pal Pathak, Anil K. Sharma & Alok R. Ray. (2017) Design and evaluation of acrylate polymeric carriers for fabrication of pH-sensitive microparticles. Drug Development and Industrial Pharmacy 43:2, pages 305-318.
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Anima Vats & Kamla Pathak. (2013) Exploiting microspheres as a therapeutic proficient doer for colon delivery: a review. Expert Opinion on Drug Delivery 10:4, pages 545-557.
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Articles from other publishers (11)

Saikat Pande, Janu Vashi & Ajay Solanki. (2022) QbD-Enabled Systematic Development of Ileo-Colonic Targeted Novel Mucoadhesive Microspheres of Flurbiprofen. Current Drug Delivery 19:3, pages 407-419.
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Deepak PatelSunil Kumar ShahChandra Kishore Tyagi. (2021) Design, Formulation and Characterization of Microspheres containing Mesalamine for the Treatment of Ulcerative Colitis. Research Journal of Science and Technology, pages 165-169.
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Tiziana M.G. Pecora, Simona Cianciolo, Alfio Catalfo, Guido De Guidi, Barbara Ruozi, Maria Chiara Cristiano, Donatella Paolino, Adriana C.E. Graziano, Massimo Fresta & Rosario Pignatello. (2016) Preparation, characterization and photostability assessment of curcumin microencapsulated within methacrylic copolymers. Journal of Drug Delivery Science and Technology 33, pages 88-97.
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Annalisa Dalmoro, Alexander Y. Sitenkov, Gaetano Lamberti, Anna Angela Barba & Rouslan I. Moustafine. (2015) Ultrasonic atomization and polyelectrolyte complexation to produce gastroresistant shell–core microparticles. Journal of Applied Polymer Science 133:6.
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Ahmed Abd El-Bary, Ahmed A. Aboelwafa & Ibrahim M. Al Sharabi. (2011) Influence of Some Formulation Variables on the Optimization of pH-dependent, Colon-targeted, Sustained-release Mesalamine Microspheres. AAPS PharmSciTech 13:1, pages 75-84.
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Ahmed Abd Elbary, Ahmed A. Aboelwafa & Ibrahim M. Al Sharabi. (2011) Once Daily, High-Dose Mesalazine Controlled-Release Tablet for Colonic Delivery: Optimization of Formulation Variables Using Box–Behnken Design. AAPS PharmSciTech 12:4, pages 1454-1464.
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Mohamed A. Alhnan & Abdul W. Basit. (2011) In-Process Crystallization of Acidic Drugs in Acrylic Microparticle Systems: Influence of Physical Factors and Drug–Polymer Interactions. Journal of Pharmaceutical Sciences 100:8, pages 3284-3293.
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S. Jose, M.T. Prema, A.J. Chacko, A. Cinu Thomas & E.B. Souto. (2011) Colon specific chitosan microspheres for chronotherapy of chronic stable angina. Colloids and Surfaces B: Biointerfaces 83:2, pages 277-283.
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Laila Fatima Ali Asghar & Sajeev Chandran. (2011) Design and evaluation of matrix base with sigmoidal release profile for colon-specific delivery using a combination of Eudragit and non-ionic cellulose ether polymers. Drug Delivery and Translational Research 1:2, pages 132-146.
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Xiao Yu & Michael V. Pishko. (2011) Release of paclitaxel from pH sensitive and biodegradable dextran based hydrogels. Soft Matter 7:19, pages 8898.
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Laila F. A. Asghar, Chetan B. Chure & Sajeev Chandran. (2009) Colon Specific Delivery of Indomethacin: Effect of Incorporating pH Sensitive Polymers in Xanthan Gum Matrix Bases. AAPS PharmSciTech 10:2, pages 418-429.
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