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Brain Injury Volume 18, 2004 - Issue 12
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Case Study

Amantadine for neurobehavioural deficits following delayed post-hypoxic encephalopathy

David B. Arciniegas Brain Injury Rehabilitation Unit, Spalding Rehabilitation Hospital, Aurora, CO, USA; Neuropsychiatry Service, Department of Psychiatry, University of Colorado School of Medicine, Denver, CO, USA; Behavioral Neurology Section, Department of Neurology, University of Colorado School of Medicine, Denver, CO, USACorrespondence[email protected]
,
Kimberly L. Frey Brain Injury Rehabilitation Unit, Spalding Rehabilitation Hospital, Aurora, CO, USA
,
C. Alan Anderson Neuropsychiatry Service, Department of Psychiatry, University of Colorado School of Medicine, Denver, CO, USA; Behavioral Neurology Section, Department of Neurology, University of Colorado School of Medicine, Denver, CO, USA
,
Kristin M. Brousseau Neuropsychiatry Service, Department of Psychiatry, University of Colorado School of Medicine, Denver, CO, USA
&
Susie N. Harris Neuropsychiatry Service, Department of Psychiatry, University of Colorado School of Medicine, Denver, CO, USA
Pages 1309-1318 | Received 13 Aug 2003, Accepted 29 Apr 2004, Published online: 03 Jul 2009

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Peggy Spauwen, Bert Ter Mors, Peter van Harten, Anne-Fleur Domensino, Rudolf Ponds & Caroline van Heugten. (2022) Efficacy and safety of amantadine as a treatment for apathy after brain injury: Two single-case experimental design studies. Neuropsychological Rehabilitation 32:6, pages 872-896.
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A FitzGerald, L Main, U Duff, J Foggo, F Rowney, N Haire & R McLean. (2021) Does amantadine maintain function in long-established brain injury? A single case experimental design. Brain Injury 35:11, pages 1443-1450.
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Heather M. Ma & Ross D. Zafonte. (2020) Amantadine and memantine: a comprehensive review for acquired brain injury. Brain Injury 34:3, pages 299-315.
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B.J. Ter Mors, A.P.M. Backx, P. Spauwen, R.W.H.M. Ponds, P.N. Van Harten & C.M. Van Heugten. (2019) Efficacy of amantadine on behavioural problems due to acquired brain injury: A systematic review. Brain Injury 33:9, pages 1137-1150.
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Sadhvi Saxena & Argye E. Hillis. (2017) An update on medications and noninvasive brain stimulation to augment language rehabilitation in post-stroke aphasia. Expert Review of Neurotherapeutics 17:11, pages 1091-1107.
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Hisanori Hasegawa & Enrique Urrea-Mendoza. (2017) Prognosis of post-cardiac-arrest anoxic encephalopathy using felbamate: A case report. Cogent Medicine 4:1.
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Dalia Cahana-Amitay, Martin L. Albert & Abigail Oveis. (2014) Psycholinguistics of aphasia pharmacotherapy: Asking the right questions. Aphasiology 28:2, pages 133-154.
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Jared B. Hammond, Jennifer Peraza & Christopher A. Pierce. A case report of long-term effects of Delayed post-hypoxic leukoencephalopathy (DPHL) following benzodiazepine overdose. The Clinical Neuropsychologist 0:0, pages 1-17.
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Articles from other publishers (24)

Henry Han Chen, Charnette Lercara, Vincent Lee & Sharon Bushi. (2024) Rehabilitation after Hypoxic and Metabolic Brain Injury in a Mountain Climber. BMJ Case Reports 17:1, pages e255794.
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James J. MahoneyIIIIII, Erin L. Winstanley, Felipe Castillo, Rachel Luba, Jennifer Marton, Daniel M. Alschuler, Ying Liu & Sandra D. Comer. (2023) A pilot study investigating cognitive impairment associated with opioid overdose. Drug and Alcohol Dependence 247, pages 109865.
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Yankun Chen, Qiumei Liu, Jian Wang, Hui Li, Yousheng Zhang, Lingling Sun & Jianli Liu. (2022) Delayed Post-Hypoxic Leukoencephalopathy Following Nitrite Poisoning: A Case Report and Review of the Literature. Frontiers in Neurology 13.
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Melissa D. Stockbridge. 2022. Aphasia. Aphasia 261 272 .
David Chachkhiani, Anil K Chimakurthy, Olinda Verdecie, Cheryl T Goyne & Edward C Mader. (2021) Delayed Toxic-Hypoxic Leukoencephalopathy As Sequela of Opioid Overdose and Cerebral Hypoxia-Ischemia. Cureus.
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Erin L. Winstanley, James J. MahoneyIIIIII, Felipe Castillo & Sandra D. Comer. (2021) Neurocognitive impairments and brain abnormalities resulting from opioid-related overdoses: A systematic review. Drug and Alcohol Dependence 226, pages 108838.
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Dallas Wolfgang Hamlin, Nuzhat Hussain & Aum Pathare. (2020) Storms and silence: a case report of catatonia and paroxysmal sympathetic hyperactivity following cerebral hypoxia. BMC Psychiatry 20:1.
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Maryam Haghighi-Morad, Zahra Naseri, Nazila Jamshidi, Hossein Hassanian-Moghaddam, Nasim Zamani & Leila Ahmad-Molaei. (2020) Methadone-induced encephalopathy: a case series and literature review. BMC Medical Imaging 20:1.
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Aleksandra Tencheva, Rui Liu, Tatyana V. Volkova, Radoslav Chayrov, Yavor Mitrev, Martin Štícha, Yuhuan Li, Hailun Jiang, Zhuorong Li, Ivanka Stankova & German L. Perlovich. (2020) Synthetic analogues of memantine as neuroprotective and influenza viral inhibitors: in vitro and physicochemical studies. Amino Acids 52:11-12, pages 1559-1580.
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T V Matveeva, V D Zhukova, A O Artemyeva, A Yu Kazantsev & R T Gaifutdinov. (2019) Delayed post-hypoxic leukoencephalopathy. Kazan medical journal 100:6, pages 985-991.
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Michelle Eventov. (2019) Amantadine minimally improves arousal in patients with severe traumatic brain injury. Clinical Research In Practice: The Journal of Team Hippocrates 5:2.
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Shiva Balan, Kartik Gupta, Parthiban Balasundaram & Ranveer Jadon. (2019) Reversible hypoxic brain injury: the penumbra conundrum of Grinker. BMJ Case Reports 12:4, pages e228670.
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Steven R. Flanagan & Heidi Fusco. 2019. Stroke Rehabilitation. Stroke Rehabilitation 185 197 .
Kristen Smolinsky & Ivona Sediva. (2018) A Case of Delayed-Onset Posthypoxic Leukoencephalopathy in a Pediatric Patient. Child Neurology Open 5, pages 2329048X1879244.
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Mary Pat Murphy. 2018. Encyclopedia of Clinical Neuropsychology. Encyclopedia of Clinical Neuropsychology 3377 3378 .
Mary Pat Murphy. 2017. Encyclopedia of Clinical Neuropsychology. Encyclopedia of Clinical Neuropsychology 1 2 .
Carlos A. Zamora, David Nauen, Robert Hynecek, Ahmet T. Ilica, Izlem Izbudak, Haris I. Sair, Sachin K. Gujar & Jay J. Pillai. (2015) Delayed posthypoxic leukoencephalopathy: a case series and review of the literature. Brain and Behavior 5:8.
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Yuya Murata, Naoki Matsumiya, Yuichi Araki, Mika Yoshida, Emina Onishi, Yoshiaki Sekiya & Hitoshi Yamada. (2015) A case of disturbance of consciousness after the return of spontaneous circulation following cardiac arrest by hanging, treated with amantadine. Nihon Shuchu Chiryo Igakukai zasshi Journal of the Japanese Society of Intensive Care Medicine 22:6, pages 536-539.
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Davin K. Quinn & Christopher C. Abbott. (2014) Catatonia After Cerebral Hypoxia: Do the Usual Treatments Apply?. Psychosomatics 55:6, pages 525-535.
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Marcelo L. Berthier, Friedemann Pulvermüller, Guadalupe Dávila, Natalia García Casares & Antonio Gutiérrez. (2011) Drug Therapy of Post-Stroke Aphasia: A Review of Current Evidence. Neuropsychology Review 21:3, pages 302-317.
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Mary Pat Murphy. 2011. Encyclopedia of Clinical Neuropsychology. Encyclopedia of Clinical Neuropsychology 2445 2447 .
Manoj Mittal, Yunxia Wang, Alan Reeves & Kathy Newell. (2010) Methadone-Induced Delayed Posthypoxic Encephalopathy: Clinical, Radiological, and Pathological Findings. Case Reports in Medicine 2010, pages 1-4.
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Anna M. Barrett & Paul J. Eslinger. (2007) Amantadine for Adynamic Speech. American Journal of Physical Medicine & Rehabilitation 86:8, pages 605-612.
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Lisa A. Lombard & Ross D. Zafonte. (2005) Agitation After Traumatic Brain Injury. American Journal of Physical Medicine & Rehabilitation 84:10, pages 797-812.
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