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Current Eye Research Volume 34, 2009 - Issue 1
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Research Article

Evidencing the Modulation of P-glycoprotein at Blood-Ocular Barriers using Gamma Scintigraphy

Srinivasan Senthilkumari Department of Ocular Pharmacology and Pharmacy, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India
,
Thirumurthy Velpandian Department of Ocular Pharmacology and Pharmacy, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India
,
Nihar Ranjan Biswas Department of Pharmacology, All India Institute of Medical Sciences, New Delhi, India
,
Assem Bhatnagar Department of Nuclear Medicine, Institute of Nuclear Medicine and Allied Sciences, Delhi, India
,
Gaurav Mittal Department of Nuclear Medicine, Institute of Nuclear Medicine and Allied Sciences, Delhi, India
&
Supriyo Ghose Department of Ocular Pharmacology and Pharmacy, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India
Pages 73-77 | Received 15 Jul 2008, Accepted 17 Oct 2008, Published online: 02 Jul 2009

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Jayabalan Nirmal, Thirumurthy Velpandian, Sundararajan Baskar Singh, Nihar Ranjan Biswas, Rajvardhan Azad, Vasantha Thavaraj, Gaurav Mittal, Aseem Bhatnagar & Supriyo Ghose. (2012) Evaluation of the Functional Importance of Organic Cation Transporters on the Ocular Disposition of Its Intravitreally Injected Substrate in Rabbits. Current Eye Research 37:12, pages 1127-1135.
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Thirumurthy Velpandian. (2009) Intraocular penetration of antimicrobial agents in ophthalmic infections and drug delivery strategies. Expert Opinion on Drug Delivery 6:3, pages 255-270.
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Articles from other publishers (8)

Imran Ahmad, Jayamanti Pandit, Yasmin Sultana, Anil K. Mishra, Puja Panwar Hazari & Mohd. Aqil. (2019) Optimization by design of etoposide loaded solid lipid nanoparticles for ocular delivery: Characterization, pharmacokinetic and deposition study. Materials Science and Engineering: C 100, pages 959-970.
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Karthik Yadav Janga, Akshaya Tatke, Surabhi Shukla, Surya P. Lamichhane, Bharathi Avula, XiangDi Wang, Monica M. Jablonski, Ikhlas A. Khan & Soumyajit Majumdar. (2018) Retina Compatible Interactions and Effective Modulation of Blood Ocular Barrier P-gp Activity by Third-Generation Inhibitors Improve the Ocular Penetration of Loperamide. Journal of Pharmaceutical Sciences 107:8, pages 2128-2135.
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Thirumurthy Velpandian & Madhu Nath. 2018. Endophthalmitis. Endophthalmitis 265 280 .
Eva M. del Amo, Anna-Kaisa Rimpelä, Emma Heikkinen, Otto K. Kari, Eva Ramsay, Tatu Lajunen, Mechthild Schmitt, Laura Pelkonen, Madhushree Bhattacharya, Dominique Richardson, Astrid Subrizi, Tiina Turunen, Mika Reinisalo, Jaakko Itkonen, Elisa Toropainen, Marco Casteleijn, Heidi Kidron, Maxim Antopolsky, Kati-Sisko Vellonen, Marika Ruponen & Arto Urtti. (2017) Pharmacokinetic aspects of retinal drug delivery. Progress in Retinal and Eye Research 57, pages 134-185.
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Jose Cunha-Vaz, Francisco Batel Marques, Rosa Fernandes, Carlos Alves & Thirumurthy Velpandian. 2016. Pharmacology of Ocular Therapeutics. Pharmacology of Ocular Therapeutics 37 63 .
Jayabalan Nirmal & Gaurav K. Jain. 2016. Pharmacology of Ocular Therapeutics. Pharmacology of Ocular Therapeutics 479 515 .
Jayabalan Nirmal, Anju Sirohiwal, Sundararajan Baskar Singh, Nihar Ranjan Biswas, Vasantha Thavaraj, Raj Vardhan Azad & Thirumurthy Velpandian. (2013) Role of organic cation transporters in the ocular disposition of its intravenously injected substrate in rabbits: Implications for ocular drug therapy. Experimental Eye Research 116, pages 27-35.
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Oudy Semoun, Sandrine Marchand, Nicolas Grégoire, Isabelle Lamarche, Christophe Adier, Laurent Laroche, Pablo Goldschmidt & William Couet. (2012) Modeling Approach To Characterize Intraocular Doripenem Pharmacokinetics after Intravenous Administration to Rabbits, with Tentative Extrapolation to Humans. Antimicrobial Agents and Chemotherapy 56:7, pages 3531-3534.
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