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Toxicological & Environmental Chemistry Volume 11, 1986 - Issue 1
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Original Articles

Transformations of pentachlorophenol

Part I: Metabolism in animals and man

G. Renner Walther‐Straub‐lnstitut für Pharmakologie und Toxikologie der Universität München, Nussbaumstrasse 26, München 2, D‐8000, F.R.G.
&
W. Mücke Bayerisches Staatsministerium für Landesentwicklung und Umweltfragen, Rosenkavalierplatz 2, München 81, D‐8000, F.R.G.
Pages 9-29 | Received 26 May 1985, Accepted 18 Jun 1985, Published online: 19 Sep 2008

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M. Dubois, Y. Grosse, J. P. Thome, P. Kremers & A. Pfohl-Leszkowicz. (1997) Metabolic activation and DNA-adducts detection as biomarkers of chlorinated pesticide exposures. Biomarkers 2:1, pages 17-24.
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G. Renner & C. Hopfer. (1990) Metabolic studies on pentachlorophenol (PCP) in rats. Xenobiotica 20:6, pages 573-582.
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G. Renner & C. Hopfer. (1990) Preparations and properties of transformation products of pentachlorophenol (PCP). Toxicological & Environmental Chemistry 25:2-3, pages 105-108.
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Guy R. Stehly & William L. Hayton. (1989) Metabolism of pentachlorophenol by fish. Xenobiotica 19:1, pages 75-81.
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Gerhard Renner. (1988) Hexachlorobenzene and its metabolism. Toxicological & Environmental Chemistry 18:1, pages 51-78.
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G. Renner, C. Hopfer, J.M. Gokel, S. Braun & W. Mücke. (1987) Subacute toxicity studies on pentachlorophenol (PCP), and the isomeric tetrachlorobenzenediols tetrachlorohydroquinone (TCH), tetrachlorocatechol (TCC), and tetrachlororesorcinol (TCR). Toxicological & Environmental Chemistry 15:4, pages 301-312.
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G. Engelhardt, P.R. Wallnöfer, W. Mücke & G. Renner. (1986) Transformations of pentachlorophenol. Toxicological & Environmental Chemistry 11:3, pages 233-252.
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Articles from other publishers (21)

Fabian Balk, Juliane Hollender & Kristin Schirmer. (2023) Investigating the bioaccumulation potential of anionic organic compounds using a permanent rainbow trout liver cell line. Environment International 174, pages 107798.
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Nikhil Maheshwari, Aijaz Ahmed Khan & Riaz Mahmood. (2023) Pentachlorophenol causes redox imbalance, inhibition of brush border membrane and metabolic enzymes, DNA damage and histological alterations in rat kidney. Pesticide Biochemistry and Physiology 190, pages 105318.
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Nikhil Maheshwari, Aijaz Ahmed Khan, Asif Ali & Riaz Mahmood. (2022) Oral administration of pentachlorophenol impairs antioxidant system, inhibits enzymes of brush border membrane, causes DNA damage and histological changes in rat intestine. Toxicology Research 11:4, pages 616-627.
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Li Mao, Chun-Hua Huang, Bo Shao, Li Qin, Miao Tang, Zhu-Ying Yan, Zhi-Sheng Liu, Jie Shao, Zhi-Guo Sheng & Ben-Zhan Zhu. (2021) The critical role of superoxide anion radicals on delaying tetrachlorohydroquinone autooxidation by penicillamine. Free Radical Biology and Medicine 163, pages 369-378.
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Li Mao, Chun-Hua Huang, Jie Shao, Li Qin, Dan Xu, Bo Shao & Ben-Zhan Zhu. (2020) An unexpected antioxidant and redox activity for the classic copper-chelating drug penicillamine. Free Radical Biology and Medicine 147, pages 150-158.
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Albert Zuehlke & Hongquan Zhang. (2017) Elevated 5-hydroxymethycytosine and cell apoptosis induced by tetrachloro-1,4-benzoquinone in mouse embryonic stem cells. Journal of Environmental Sciences 51, pages 1-4.
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Constanze Pietsch, Juliane Hollender, Falk Dorusch & Patricia Burkhardt-Holm. (2014) Cytotoxic effects of pentachlorophenol (PCP) and its metabolite tetrachlorohydroquinone (TCHQ) on liver cells are modulated by antioxidants. Cell Biology and Toxicology 30:4, pages 233-252.
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Hans-Joachim Lehmler, Xianran He, Xueshu Li, Michael W. Duffel & Sean Parkin. (2013) Effective synthesis of sulfate metabolites of chlorinated phenols. Chemosphere 93:9, pages 1965-1971.
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Ben-Zhan Zhu, Jun-Ge Zhu, Rui-Mei Fan & Li Mao. 2011. 1 43 .
Ben-Zhan Zhu & Guo-Qiang Shan. (2009) Potential Mechanism for Pentachlorophenol-Induced Carcinogenicity: A Novel Mechanism for Metal-Independent Production of Hydroxyl Radicals. Chemical Research in Toxicology 22:6, pages 969-977.
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Hayrettin Ozan Gulcan, Yungang Liu & Michael W. Duffel. (2008) Pentachlorophenol and Other Chlorinated Phenols Are Substrates for Human Hydroxysteroid Sulfotransferase hSULT2A1. Chemical Research in Toxicology 21:8, pages 1503-1508.
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Xiaohua Liu, Jiangning Chen, Hongxia Yu, Jinsong Zhao, John P. Giesy & Xiaorong Wang. (2006) Quantitative structure activity relationship (QSAR) for toxicity of chlorophenols on L929 cells in vitro. Chemosphere 64:10, pages 1619-1626.
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Jack R. Plimmer & Derek W. Gammon. 2003. Encyclopedia of Agrochemicals. Encyclopedia of Agrochemicals.
Martin D. Webb, Greg Ewbank, Joy Perkins & Alan J. McCarthy. (2001) Metabolism of pentachlorophenol by Saccharomonospora viridis strains isolated from mushroom compost. Soil Biology and Biochemistry 33:14, pages 1903-1914.
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Ben-Zhan Zhu, Nahum Kitrossky & Mordechai Chevion. (2000) Evidence for Production of Hydroxyl Radicals by Pentachlorophenol Metabolites and Hydrogen Peroxide: A Metal-Independent Organic Fenton Reaction. Biochemical and Biophysical Research Communications 270:3, pages 942-946.
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Irene Witte, Ben-Zhan Zhu, Aloys Lueken, Dino Magnani, Helge Stossberg & Mordechai Chevion. (2000) Protection by desferrioxamine and other hydroxamic acids against tetrachlorohydroquinone-induced cyto- and genotoxicity in human fibroblasts. Free Radical Biology and Medicine 28:5, pages 693-700.
Crossref
Sarah J. Young, Antony A. Dowman & David C. Cowell. (1999) The Detection of Pentachlorophenol by Its Inhibitory Effectiveness on Lactate Dehydrogenase of Rabbit Muscle and Bovine Heart. Pesticide Biochemistry and Physiology 64:1, pages 1-8.
Crossref
Bhupendra S. Kaphalia. (1991) Fatty acid conjugates of chlorinated phenols and their high-performance liquid chromatographic analysis. Journal of Chromatography A 537, pages 85-92.
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Thomas A. Gasiewicz. 1991. Classes of Pesticides. Classes of Pesticides 1191 1269 .
J.G. Steiert & R.L. Crawford. (1986) Catabolism of pentachlorophenol by a Flavobacterium sp. Biochemical and Biophysical Research Communications 141:2, pages 825-830.
Crossref
G Ruckdeschel & G Renner. (1986) Effects of pentachlorophenol and some of its known and possible metabolites on fungi. Applied and Environmental Microbiology 51:6, pages 1370-1372.
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