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L Leistad, AJ Feuerherm, A Faxvaag & B Johansen. (2011) Multiple phospholipase A2 enzymes participate in the inflammatory process in osteoarthritic cartilage. Scandinavian Journal of Rheumatology 40:4, pages 308-316.
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XW Shi, X Guo, AL Lv, L Kang, YL Zhou, YZ Zhang, XM Wu & YD Bai. (2010) Heritability estimates and linkage analysis of 23 short tandem repeat loci on chromosomes 2, 11, and 12 in an endemic osteochondropathy in China. Scandinavian Journal of Rheumatology 39:3, pages 259-265.
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Articles from other publishers (32)
Clément Veys, Flavie Boulouard, Abderrahim Benmoussa, Manon Jammes, Emilie Brotin, Françoise Rédini, Laurent Poulain, Nicolas Gruchy, Christophe Denoyelle, Florence Legendre & Philippe Galera. (2023) MiR-4270 acts as a tumor suppressor by directly targeting Bcl-xL in human osteosarcoma cells. Frontiers in Oncology 13.
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Mario Simental-Mendía, Sonia Amelia Lozano-Sepúlveda, Marsela Garza-Tapia, Jorge Lara-Arias, Carlos Alberto Acosta-Olivo, Félix Vilchez-Cavazos & Víctor Manuel Peña-Martínez. (2023) The Effects of the Combination of Rhein and Platelet-Rich Plasma on Human Articular Chondrocytes. Life 13:8, pages 1723.
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Chuanshan Yao & Feng Wang. (2022) Inhibition of hypoxia‐induced HIF‐1α‐mediated autophagy enhances the in vitro antitumor activity of rhein in pancreatic cancer cells. Journal of Applied Toxicology 42:12, pages 1937-1947.
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Qingluo Zhou, Qun Ren, Linhui Jiao, Jishang Huang, Jun Yi, Jincai Chen, Jinliang Lai, Guanglin Ji & Tiansheng Zheng. (2022) The potential roles of JAK/STAT signaling in the progression of osteoarthritis. Frontiers in Endocrinology 13.
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Vishal Patel, Amit Joharapurkar & Mukul Jain. (2022) Therapeutic Potential of Diacerein in Management of Pain. Current Drug Research Reviews 14:3, pages 215-224.
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Ravi Kant, Parul Rao, Gyaneshwer Tank & Rohit Gupta. (2022) Role of bioactive collagen peptide in the management of monoidoacetate induced osteoarthritis and its comparison with diacerein in rat model: An experimental study. Journal of Bone and Joint Diseases 37:3, pages 152.
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Jordi Monfort, Xavier Carné, Benjamín Abarca, Sergio Giménez, Montserrat Romera, Ingrid Möller, Marco Bibas, Marianna Vitaloni, Aina Batlle & Josep Vergés. (2021) Experts document about an adequate utilization of SYSADOAs in controversial clinical situations. Reumatología Clínica (English Edition) 17:10, pages 595-600.
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Jordi Monfort, Xavier Carné, Benjamín Abarca, Sergio Giménez, Montserrat Romera, Ingrid Möller, Marco Bibas, Marianna Vitaloni, Aina Batlle & Josep Vergés. (2021) Documento de expertos sobre el uso apropiado de los SYSADOA en situaciones clínicas controvertidas. Reumatología Clínica 17:10, pages 595-600.
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Clément Veys, Abderrahim Benmoussa, Romain Contentin, Amandine Duchemin, Emilie Brotin, Jérôme E. Lafont, Yannick Saintigny, Laurent Poulain, Christophe Denoyelle, Magali Demoor, Florence Legendre & Philippe Galéra. (2021) Tumor Suppressive Role of miR-342-5p in Human Chondrosarcoma Cells and 3D Organoids. International Journal of Molecular Sciences 22:11, pages 5590.
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Hongjuan Wang, Dezhi Yang, Li Li, Shiying Yang, Guanhua Du & Yang Lu. (2020) Anti-inflammatory Effects and Mechanisms of Rhein, an Anthraquinone Compound, and Its Applications in Treating Arthritis: A Review. Natural Products and Bioprospecting 10:6, pages 445-452.
Crossref
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David Monteiro Barbosa, Pia Fahlbusch, Daniella Herzfeld de Wiza, Sylvia Jacob, Ulrike Kettel, Hadi Al-Hasani, Martina Krüger, D. Margriet Ouwens, Sonja Hartwig, Stefan Lehr, Jorg Kotzka & Birgit Knebel. (2020) Rhein, a novel Histone Deacetylase (HDAC) inhibitor with antifibrotic potency in human myocardial fibrosis. Scientific Reports 10:1.
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Jiacai Hu, Daochun Wang, Hao Wu, Zhijie Yang, Na Yang & Junjun Dong. (2019) Long non-coding RNA ANRIL-mediated inflammation response is involved in protective effect of rhein in uric acid nephropathy rats. Cell & Bioscience 9:1.
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Crossref
Fen Hu, Donglan Zhu, Weiwei Pei, Imshik Lee, Xinzheng Zhang, Leiting Pan & Jingjun Xu. (2019) Rhein inhibits ATP-triggered inflammatory responses in rheumatoid rat fibroblast-like synoviocytes. International Immunopharmacology 75, pages 105780.
Crossref
Crossref
Zuzana Cockova, Hana Ujcikova, Petr Telensky & Jiri Novotny. (2019) Protein profiling of SH-SY5Y neuroblastoma cells: The effect of rhein. Journal of Biosciences 44:4.
Crossref
Crossref
Baoyin Ren, Weijia Guo, Yawei Tang, Jing Zhang, Nan Xiao, Lin Zhang & Weiling Li. (2019) Rhein Inhibits the Migration of Ovarian Cancer Cells through Down-Regulation of Matrix Metalloproteinases. Biological and Pharmaceutical Bulletin 42:4, pages 568-572.
Crossref
Crossref
Rikang Wang, Gang Chen, Shuai Zhang, Rahul Previn, Di Chen, Yi Jin & Guangqian Zhou. (2018) Role of Forkhead Box O Transcription Factors in Oxidative Stress-Induced Chondrocyte Dysfunction: Possible Therapeutic Target for Osteoarthritis?. International Journal of Molecular Sciences 19:12, pages 3794.
Crossref
Crossref
Mouloud Bouyoucef, Rodolphe Rakic, Tangni Gómez-Leduc, Thomas Latire, Frédéric Marin, Sylvain Leclercq, Franck Carreiras, Antoine Serpentini, Jean-Marc Lebel, Philippe Galéra & Florence Legendre. (2018) Regulation of Extracellular Matrix Synthesis by Shell Extracts from the Marine Bivalve Pecten maximus in Human Articular Chondrocytes— Application for Cartilage Engineering. Marine Biotechnology 20:4, pages 436-450.
Crossref
Crossref
丽 缪. (2018) Research Progress on Synthesis and Biological Activity of Rhubarb Acid Derivatives. Hans Journal of Medicinal Chemistry 06:02, pages 29-36.
Crossref
Crossref
Chengjin Zhao, Qingbai Liu & Kunzheng Wang. (2017) Artesunate attenuates ACLT-induced osteoarthritis by suppressing osteoclastogenesis and aberrant angiogenesis. Biomedicine & Pharmacotherapy 96, pages 410-416.
Crossref
Crossref
Yuan Yuan, Hua Yang, Linghua Kong, Yuan Li, Ping Li, Hongjian Zhang & Jianqing Ruan. (2017) Interaction between rhein acyl glucuronide and methotrexate based on human organic anion transporters. Chemico-Biological Interactions 277, pages 79-84.
Crossref
Crossref
Girish C. Mohan, Huayi Zhang, Lei Bao, Benjamin Many & Lawrence S. Chan. (2017) Diacerein inhibits the pro-atherogenic & pro-inflammatory effects of IL-1 on human keratinocytes & endothelial cells. PLOS ONE 12:3, pages e0173981.
Crossref
Crossref
Erica M. TenBroek, Laurie Yunker, Mae Foster Nies & Alison M. Bendele. (2016) Randomized controlled studies on the efficacy of antiarthritic agents in inhibiting cartilage degeneration and pain associated with progression of osteoarthritis in the rat. Arthritis Research & Therapy 18:1.
Crossref
Crossref
Hao Sun, Guangwen Luo, Dahui Chen & Zheng Xiang. (2016) A Comprehensive and System Review for the Pharmacological Mechanism of Action of Rhein, an Active Anthraquinone Ingredient. Frontiers in Pharmacology 7.
Crossref
Crossref
Birgit Lohberger, Andreas Leithner, Nicole Stuendl, Heike Kaltenegger, Werner Kullich & Bibiane Steinecker-Frohnwieser. (2015) Diacerein retards cell growth of chondrosarcoma cells at the G2/M cell cycle checkpoint via cyclin B1/CDK1 and CDK2 downregulation. BMC Cancer 15:1.
Crossref
Crossref
Maryam Malmir, Eugénia Ferreira, Rita Serrano, Elsa T. Gomes, Manuela Caniça & Olga Silva. (2015) In vitro anti-Neisseria gonorrhoeae activity of Senna podocarpa root extracts. Industrial Crops and Products 76, pages 467-471.
Crossref
Crossref
Siu Wai Tsang & Zhao-Xiang Bian. (2015) Anti-fibrotic and Anti-tumorigenic Effects of Rhein, a Natural Anthraquinone Derivative, in Mammalian Stellate and Carcinoma Cells. Phytotherapy Research 29:3, pages 407-414.
Crossref
Crossref
Yan-Xi Zhou, Wei Xia, Wei Yue, Cheng Peng, Khalid Rahman & Hong Zhang. (2015) Rhein: A Review of Pharmacological Activities. Evidence-Based Complementary and Alternative Medicine 2015, pages 1-10.
Crossref
Crossref
B. Steinecker-Frohnwieser, L. Weigl, W. Kullich & B. Lohberger. (2014) The disease modifying osteoarthritis drug diacerein is able to antagonize pro inflammatory state of chondrocytes under mild mechanical stimuli. Osteoarthritis and Cartilage 22:7, pages 1044-1052.
Crossref
Crossref
Mei Li, Philbert Lee, Yao Zhang, ZhiYuan Ma, Feng Yang, ZuPing Zhou, XiaoYang Wu & Hong Liang. (2014) X-ray Crystallographic and Fluorometric Analysis of the Interactions of Rhein to Human Serum Albumin. Chemical Biology & Drug Design 83:2, pages 167-173.
Crossref
Crossref
Hao Li, Chengzhen Liang, Qixin Chen & Zhengming Yang. (2011) Rhein: A potential biological therapeutic drug for intervertebral disc degeneration. Medical Hypotheses 77:6, pages 1105-1107.
Crossref
Crossref
Guo-lin Zhang, De-zai Dai, Tao Xi, Xiao-dong Cong, Yun Zhang & Yin Dai. (2011) Isoproterenol-induced FKBP12.6/12 downregulation is modulated by ETA and ETB receptors and reversed by argirhein, a derivative of rhein. Acta Pharmacologica Sinica 32:2, pages 223-229.
Crossref
Crossref
Johanne Martel-PelletierJean-Pierre Pelletier. (2010) Effects of diacerein at the molecular level in the osteoarthritis disease process. Therapeutic Advances in Musculoskeletal Disease 2:2, pages 95-104.
Crossref
Crossref