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Hemoglobin
international journal for hemoglobin research
Volume 33, 2009 - Issue 1
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Original Article

Molecular Heterogeneity of β-Thalassemia in Algeria: How to Face Up to a Major Health Problem

Nassima Boudrahem-Addour Laboratoire de Biologie Cellulaire et Moléculaire, Faculté des Sciences Biologiques, Université des Sciences et de la Technologie Houari Boumediène, Alger, Algérie
,
Nadia Zidani Service d'Hématologie, Hôpital Isaad Hassani, CHU Beni-Messous, Alger, Algérie
,
Nathalie Carion Assistance Publique-Hôpitaux de Paris, Laboratoire de Biochimie et de Génétique Moléculaire, Hôpital Cochin, Paris, France
,
Dominique Labie INSERM U567, Paris, France
,
Meriem Belhani Service d'Hématologie, Hôpital Isaad Hassani, CHU Beni-Messous, Alger, Algérie
&
Cherif Beldjord Assistance Publique-Hôpitaux de Paris, Laboratoire de Biochimie et de Génétique Moléculaire, Hôpital Cochin, Paris, France; INSERM U567, Paris, France; Université Paris Descartes, Institut Cochin, Paris, FranceCorrespondence[email protected]
Pages 24-36 | Received 11 Aug 2008, Accepted 27 Aug 2008, Published online: 07 Jul 2009

Citations (18)

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Aisha Moeen Khan, Asma Mohammed Al-Sulaiti, Salma Younes, Mohamed Yassin & Hatem Zayed. (2021) The spectrum of beta-thalassemia mutations in the 22 Arab countries: a systematic review. Expert Review of Hematology 14:1, pages 109-122.
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Wissem Abdaoui, Djamel Eddine Benouareth, Amel Djenouni, Celine Renoux, Fatiha Grifi, Adel Gouri, Fateh Athamnia, Manel Benalioua & Philippe Joly. (2019) Genetic Background of β-Thalassemia in Northeast Algeria with Assessment of the Thalassemia Severity Score and Description of a new β0-Thalassemia Frameshift Mutation (HBB: c.374dup; p.Pro126Thrfs*15) . Hemoglobin 43:4-5, pages 223-228.
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Nasir A.S. Al-Allawi, Bassam M.S. Al-Mousawi, Ameer I.A. Badi & Sana D. Jalal. (2013) The Spectrum of β-Thalassemia Mutations in Baghdad, Central Iraq. Hemoglobin 37:5, pages 444-453.
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Amel Haj Khelil, Sabri Denden, Nadia Leban, Houria Daimi, Ramzi Lakhdhar, Gérard Lefranc, Jemni Ben Chibani & Pascale Perrin. (2010) Hemoglobinopathies in North Africa: A Review. Hemoglobin 34:1, pages 1-23.
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Articles from other publishers (14)

Ekta Rao, Sandip Kumar Chandraker, Mable Misha Singh & Ravindra Kumar. (2024) Global distribution of β-thalassemia mutations: An update. Gene 896, pages 148022.
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Hui-Juan Zhang, Xiao-Mei Hu & De-Dong Liu. (2023) The research for various genotypes and phenotypes related to rare -90 (C>T) β-thalassemia mutation in Ganzhou city, Southern China. Frontiers in Hematology 2.
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Taher Mahmoud, Chaima Sahli, Sondess Hadj Fredj, Yessine Amri, Rim Othmani, Ghaber S. Mohamed, Ekhtelbenina Zein & Taieb Messaoud. (2022) Epidemiological and molecular study of hemoglobinopathies in Mauritanian patients. Molecular Genetics & Genomic Medicine 10:10.
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Ihab Belmokhtar, Saida Lhousni, Mounia Elidrissi Errahhali, Ayad Ghanam, Manal Elidrissi Errahhali, Zaina Sidqi, Meryem Ouarzane, Majida Charif, Mohammed Bellaoui, Redouane Boulouiz & Noufissa Benajiba. (2022) Molecular heterogeneity of β‐thalassemia variants in the Eastern region of Morocco. Molecular Genetics & Genomic Medicine 10:8.
Crossref
Adivitch Sripusanapan, Arunee Phusua, Kanda Fanhchaksai & Pimlak Charoenkwan. (2020) Compound heterozygosity of a silent beta‐thalassemia mutation at the 3′‐untranslated region ( HBB : c.*132 C>T) and beta‐zero thalassemia results in thalassemia intermedia . Pediatric Blood & Cancer 67:4.
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Lilia Romdhane, Nessrine MezziYosr HamdiGhada El-Kamah, Abdelhamid Barakat & Sonia Abdelhak. (2019) Consanguinity and Inbreeding in Health and Disease in North African Populations. Annual Review of Genomics and Human Genetics 20:1, pages 155-179.
Crossref
Hala A. Al-Kherbash, Ahmed Al-Awdi & Nawal S. Hasan. (2017) Pattern and clinical profile of thalassemia among pediatric patients attending the Yemeni Society Centers for Thalassemia and Genetic Blood Disorders in Yemen. The Scientific Journal of Al-Azhar Medical Faculty, Girls 1:2, pages 43-56.
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Nikolaos Sousos, Despoina Adamidou, Philippos Klonizakis, Alexandra Agapidou, Stamatia Theodoridou, Georgios Spanos, Kyriakos Psarras, Evaggelia Vetsiou, Timoleon-Achilleas Vyzantiadis & Efthymia Vlachaki. (2017) Presence of the IVS-I-6-Mutated Allele in Beta-Thalassemia Major Patients Correlates with Extramedullary Hematopoiesis Incidence. Acta Haematologica 137:3, pages 175-182.
Crossref
Kais Douzi, Imen Moumni, Amine Zorai, Maha Ben Mustapha, Ikbel Mosbahi Ben Mansour, Chaouachi Dorra & Abbes Salem. (2015) Two new β + ‐thalassemia mutation [ β ‐56 (G → C); HBBc. −106 G → C ] and [ β −83 (G → A); HBBc. −133 G → A ] described among the Tunisian population . American Journal of Human Biology 27:5, pages 716-719.
Crossref
Manal Michel Wilson, Hanan Al-Wakeel, Fadwa Said, Mona El-Ghamrawy, Mary Assaad & Amal El-Beshlawy. (2015) Study of the effect of HFE gene mutations on iron overload in Egyptian thalassemia patients. Egyptian Journal of Medical Human Genetics 16:2, pages 129-133.
Crossref
Fadwa Said & Amina Abdel-Salam. (2015) XmnI polymorphism: Relation to β-thalassemia phenotype and genotype in Egyptian Children. Egyptian Journal of Medical Human Genetics 16:2, pages 123-127.
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Hanan A. Hamamy & Nasir A. S. Al-Allawi. (2012) Epidemiological profile of common haemoglobinopathies in Arab countries. Journal of Community Genetics 4:2, pages 147-167.
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Nongthombam AchoubiMohammad AsgharKallur Nava SaraswathyBenrithung Murry. (2012) Prevalence of β-Thalassemia and Hemoglobin E in Two Migrant Populations of Manipur, North East India. Genetic Testing and Molecular Biomarkers 16:10, pages 1195-1200.
Crossref
Shirley Henderson, Adele Timbs, Janice McCarthy, Alice Gallienne, Margaretha Van Mourik, Gillian Masters, Alison May, Mohamed S.M. Khalil, Anna Schuh & John Old. (2009) Incidence of haemoglobinopathies in various populations — The impact of immigration. Clinical Biochemistry 42:18, pages 1745-1756.
Crossref

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