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Research Article

Design and In Vitro Evaluation of Polymeric Formulae of Simvastatin for Local Bone Induction

Pages 1199-1206 | Published online: 25 Sep 2008

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Heba A. Hazzah, Ragwa M. Farid, Maha M. A. Nasra, Mennatallah Zakaria, Yousria Gawish, Magda A. El-Massik & Ossama Y. Abdallah. (2016) A new approach for treatment of precancerous lesions with curcumin solid–lipid nanoparticle-loaded gels: in vitro and clinical evaluation. Drug Delivery 23:4, pages 1409-1419.
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Articles from other publishers (14)

Xiaoke Xu, Zhenshan Jia, Ningrong Chen, Subodh M. Lele, Shabnam Arash, Richard A. Reinhardt, Amy C. Killeen & Dong Wang. (2023) The Development of Thermoresponsive Polymeric Simvastatin Prodrug for the Treatment of Experimental Periodontitis in Rats. Molecular Pharmaceutics 20:11, pages 5631-5645.
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Simona Santonocito, Salvatore Ferlito, Alessandro Polizzi, Vincenzo Ronsivalle, Giuseppe Reitano, Antonino Lo Giudice & Gaetano Isola. (2023) Impact exerted by scaffolds and biomaterials in periodontal bone and tissue regeneration engineering: new challenges and perspectives for disease treatment. Exploration of Medicine, pages 215-234.
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Ahmed U. Ali, Ahmed Mortada, Mohamed A. Safwat & Tahani H. El-Faham. (2021) Performance of simvastatin microsponges as a local treatment for chronic periodontitis – Randomized clinical trial. Journal of Drug Delivery Science and Technology 64, pages 102583.
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Ningrong Chen, Rongguo Ren, Xin Wei, Roshni Mukundan, Guojuan Li, Xiaoke Xu, Gang Zhao, Zhifeng Zhao, Subodh M. Lele, Richard A. Reinhardt & Dong Wang. (2021) Thermoresponsive Hydrogel-Based Local Delivery of Simvastatin for the Treatment of Periodontitis. Molecular Pharmaceutics 18:5, pages 1992-2003.
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Catherine Petit, Fareeha Batool, Céline Stutz, Nicolas Anton, Andrey Klymchenko, Thierry Vandamme, Nadia Benkirane-Jessel & Olivier Huck. (2020) Development of a thermosensitive statin loaded chitosan-based hydrogel promoting bone healing. International Journal of Pharmaceutics 586, pages 119534.
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Amira Sayed Hanafy & Samar O. El-Ganainy. (2020) Thermoresponsive Hyalomer intra-articular hydrogels improve monoiodoacetate-induced osteoarthritis in rats. International Journal of Pharmaceutics 573, pages 118859.
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William AcreeJr.Jr. & James S. Chickos. (2017) Phase Transition Enthalpy Measurements of Organic and Organometallic Compounds and Ionic Liquids. Sublimation, Vaporization, and Fusion Enthalpies from 1880 to 2015. Part 2. C11–C192. Journal of Physical and Chemical Reference Data 46:1.
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Yashu Yao, Mengxin Xia, Huizhen Wang, Guowen Li, Hongyi Shen, Guang Ji, Qianchao Meng & Yan Xie. (2016) Preparation and evaluation of chitosan-based nanogels/gels for oral delivery of myricetin. European Journal of Pharmaceutical Sciences 91, pages 144-153.
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P. Díaz-Rodríguez & M. Landin. 2016. Advanced Materials Interfaces. Advanced Materials Interfaces 325 378 .
Anil Singh Chauhan, Anisha Maria & Anil Managutti. (2014) Efficacy of Simvastatin in Bone Regeneration After Surgical Removal of Mandibular Third Molars: A Clinical Pilot Study. Journal of Maxillofacial and Oral Surgery 14:3, pages 578-585.
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Ghada Mansour, Adham Al Ashwah & Azza Koura. (2014) Evaluation of Simvastatin Grafting Around Immediate Dental Implants in Dogs. Implant Dentistry 23:2, pages 195-199.
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Ricardo G. Simões, Carlos E. S. Bernardes, Hermínio P. Diogo, Filipe Agapito & Manuel E. Minas da Piedade. (2013) Energetics and Structure of Simvastatin. Molecular Pharmaceutics 10:7, pages 2713-2722.
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Radheshyam Tiwari & Kamla Pathak. (2011) Statins therapy: a review on conventional and novel formulation approaches. Journal of Pharmacy and Pharmacology 63:8, pages 983-998.
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Ju Hyeong Jeon, Ward T. Piepgrass, Yi-Ling Lin, Mark V. Thomas & David A. Puleo. (2008) Localized Intermittent Delivery of Simvastatin Hydroxyacid Stimulates Bone Formation in Rats. Journal of Periodontology 79:8, pages 1457-1464.
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