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Review Article

Pharmaceutical Applications of Hot-Melt Extrusion: Part II

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Pages 1043-1057 | Published online: 25 Sep 2008

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Arabella M. McLaughlin, John Robertson & Xiong-Wei Ni. (2020) Investigation of dissolution rate kinetics of bulk pharmaceutical feed streams within a stirred tank vessel and a twin screw extruder. Pharmaceutical Development and Technology 25:2, pages 219-226.
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A. L. Kelly, T. Gough, M. Isreb, R. Dhumal, J. W. Jones, S. Nicholson, A. B. Dennis & A. Paradkar. (2018) In-process rheometry as a PAT tool for hot melt extrusion. Drug Development and Industrial Pharmacy 44:4, pages 670-676.
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Bader B. Alsulays, Vijay Kulkarni, Sultan M. Alshehri, Bjad K. Almutairy, Eman A. Ashour, Joseph T. Morott, Abdullah S. Alshetaili, Jun-Bom Park, Roshan V. Tiwari & Michael A. Repka. (2017) Preparation and evaluation of enteric coated tablets of hot-melt extruded lansoprazole. Drug Development and Industrial Pharmacy 43:5, pages 789-796.
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Abdullah S. Alshetaili, Bjad K. Almutairy, Saad M. Alshahrani, Eman A. Ashour, Roshan V. Tiwari, Sultan M. Alshehri, Xin Feng, Bader B. Alsulays, Soumyajit Majumdar, Nigel Langley, Karl Kolter, Andreas Gryczke, Scott T. Martin & Michael A. Repka. (2016) Optimization of hot melt extrusion parameters for sphericity and hardness of polymeric face-cut pellets. Drug Development and Industrial Pharmacy 42:11, pages 1833-1841.
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Michał Teżyk, Bartłomiej Milanowski, Andrzej Ernst & Janina Lulek. (2016) Recent progress in continuous and semi-continuous processing of solid oral dosage forms: a review. Drug Development and Industrial Pharmacy 42:8, pages 1195-1214.
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Raju Onkar Sonawane & Savita Dattatraya Patil. (2016) Formulation Aspects and Effect of Critical Factors for Designing Extended Release Pellets: An Updated Review. Polymer-Plastics Technology and Engineering 55:9, pages 976-989.
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Chinna Reddy Palem, Narendar Reddy Dudhipala, Sunil Kumar Battu, Michael A. Repka & Madhusudan Rao Yamsani. (2016) Development, optimization and in vivo characterization of domperidone-controlled release hot-melt-extruded films for buccal delivery. Drug Development and Industrial Pharmacy 42:3, pages 473-484.
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Eman A. Ashour, Vijay Kulkarni, Bjad Almutairy, Jun-Bom Park, Sejal P. Shah, Soumyajit Majumdar, Zhuoyang Lian, Elanor Pinto, Vivian Bi, Thomas Durig, Scott T. Martin & Michael A. Repka. (2016) Influence of pressurized carbon dioxide on ketoprofen-incorporated hot-melt extruded low molecular weight hydroxypropylcellulose. Drug Development and Industrial Pharmacy 42:1, pages 123-130.
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Justin R. Hughey, Justin M. Keen, Ryan C. Bennett, Sakae Obara & James W. McGinity. (2015) The incorporation of low-substituted hydroxypropyl cellulose into solid dispersion systems. Drug Development and Industrial Pharmacy 41:8, pages 1294-1301.
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Elena Ravina-Eirin, J. L. Gomez-Amoza & Ramón Martínez-Pacheco. (2015) Drug dispersion degree and drug dissolution rate in Hybrane S1200-based instant-release matricial particles prepared by hot melt extrusion. Drug Development and Industrial Pharmacy 41:6, pages 1000-1005.
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Ryan C. Bennett, Chris Brough, Dave A. Miller, Kevin P. O’Donnell, Justin M. Keen, Justin R. Hughey, Robert O. Williams$suffix/text()$suffix/text() & James W. McGinity. (2015) Preparation of amorphous solid dispersions by rotary evaporation and KinetiSol Dispersing: approaches to enhance solubility of a poorly water-soluble gum extract. Drug Development and Industrial Pharmacy 41:3, pages 382-397.
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Muhammad Hanif, Muhammad Zaman & Vesh Chaurasiya. (2015) Polymers used in buccal film: a review. Designed Monomers and Polymers 18:2, pages 105-111.
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Nathan Boersen, Thomas Wai-Yip Lee, Xiaole (George) Shen & Ho-Wah Hui. (2014) A preliminary assessment of the impact of hot-melt extrusion on the physico-mechanical properties of a tablet. Drug Development and Industrial Pharmacy 40:10, pages 1386-1394.
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K. Vithani, Y. Cuppok, S. Mostafa, I. J. Slipper, M. J. Snowden & D. Douroumis. (2014) Diclofenac sodium sustained release hot melt extruded lipid matrices. Pharmaceutical Development and Technology 19:5, pages 531-538.
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Elena Raviña-Eirín, Jose Luis Gómez-Amoza & Ramón Martínez-Pacheco. (2013) Utility of the hyperbranched polymer Hybrane S1200 for production of instant-release particles by hot melt extrusion. Drug Development and Industrial Pharmacy 39:7, pages 1107-1112.
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Gena Dalziel, Ewa Nauka, Feng Zhang, Sanjeev Kothari & Minli Xie. (2013) Assessment of granulation technologies for an API with poor physical properties. Drug Development and Industrial Pharmacy 39:7, pages 985-995.
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Chinna Reddy Palem, Sunil Kumar Battu, Sindhuri Maddineni, Ramesh Gannu, Michael A. Repka & Madhusudan Rao Yamsani. (2013) Oral transmucosal delivery of domperidone from immediate release films produced via hot-melt extrusion technology. Pharmaceutical Development and Technology 18:1, pages 186-195.
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Weibin Deng, Soumyajit Majumdar, Abhilasha Singh, Sejal Shah, Noorullah Naqvi Mohammed, Seongbong Jo, Elanor Pinto, Divya Tewari, Thomas Durig & Michael A. Repka. (2013) Stabilization of fenofibrate in low molecular weight hydroxypropylcellulose matrices produced by hot-melt extrusion. Drug Development and Industrial Pharmacy 39:2, pages 290-298.
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M. Maniruzzaman, M. M. Rana, J. S. Boateng, J. C. Mitchell & D. Douroumis. (2013) Dissolution enhancement of poorly water-soluble APIs processed by hot-melt extrusion using hydrophilic polymers. Drug Development and Industrial Pharmacy 39:2, pages 218-227.
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Indrajit Ghosh, Radha Vippagunta, Shoufeng Li & Sudha Vippagunta. (2012) Key considerations for optimization of formulation and melt-extrusion process parameters for developing thermosensitive compound. Pharmaceutical Development and Technology 17:4, pages 502-510.
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Rashmi R. Panda & Ashok K. Tiwary. (2012) Hot melt granulation: a facile approach for monolithic osmotic release tablets. Drug Development and Industrial Pharmacy 38:4, pages 447-461.
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Michael A Repka, Sejal Shah, Jiannan Lu, Sindhuri Maddineni, Joe Morott, Ketaki Patwardhan & Noorullah Naqvi Mohammed. (2012) Melt extrusion: process to product. Expert Opinion on Drug Delivery 9:1, pages 105-125.
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Jingwen Hou, Changyan Li, Liang Cheng, Shengrong Guo, Yaqiong Zhang & Tingting Tang. (2011) Study on hydrophilic 5-fluorouracil release from hydrophobic poly(ϵ-caprolactone) cylindrical implants. Drug Development and Industrial Pharmacy 37:9, pages 1068-1075.
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Parijat Kanaujia, Grace Lau, Wai Kiong Ng, Effendi Widjaja, Martin Schreyer, Andrea Hanefeld, Matthias Fischbach, Christoph Saal, Mario Maio & Reginald B.H. Tan. (2011) Investigating the effect of moisture protection on solid-state stability and dissolution of fenofibrate and ketoconazole solid dispersions using PXRD, HSDSC and Raman microscopy. Drug Development and Industrial Pharmacy 37:9, pages 1026-1035.
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Fu Jijun, Xu Lishuang, Wang Xiaoli, Zhang Shu, Tao Xiaoguang, Zhao Xingna, He Haibing & Tang Xing. (2011) Nimodipine (NM) tablets with high dissolution containing NM solid dispersions prepared by hot-melt extrusion. Drug Development and Industrial Pharmacy 37:8, pages 934-944.
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Dennis Douroumis. (2011) Orally disintegrating dosage forms and taste-masking technologies; 2010. Expert Opinion on Drug Delivery 8:5, pages 665-675.
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Michael A Repka, Soumyajit Majumdar, Sunil Kumar Battu, Ramesh Srirangam & Sampada B Upadhye. (2008) Applications of hot-melt extrusion for drug delivery. Expert Opinion on Drug Delivery 5:12, pages 1357-1376.
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