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Research Article

Preparation and Characterization of an Oridonin Nanosuspension for Solubility and Dissolution Velocity Enhancement

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Pages 1332-1339 | Published online: 25 Sep 2008

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Yuzhou Shen & Haitao Ma. (2022) Oridonin-loaded lipid-coated calcium phosphate nanoparticles: preparation, characterization, and application in A549 lung cancer. Pharmaceutical Development and Technology 27:5, pages 598-605.
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Huagang Sheng, Yuanyuan Zhang, Jijuan Nai, Shaohua Wang, Mengmeng Dai, Guitao Lin, Liqiao Zhu & Qiang Zhang. (2020) Preparation of oridonin nanocrystals and study of their endocytosis and transcytosis behaviours on MDCK polarized epithelial cells. Pharmaceutical Biology 58:1, pages 518-527.
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Ayse Nur Oktay, Sibel Ilbasmis-Tamer & Nevin Celebi. (2019) The effect of critical process parameters of the high pressure homogenization technique on the critical quality attributes of flurbiprofen nanosuspensions . Pharmaceutical Development and Technology 24:10, pages 1278-1286.
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Xuan Shi, Tingting Peng, Ying Huang, Liling Mei, Yukun Gu, Jiayuan Huang, Ke Han, Ge Li, Chunli Hu, Xin Pan & Chuanbin Wu. (2017) Comparative studies on glycerol monooleate- and phytantriol-based cubosomes containing oridonin in vitro and in vivo. Pharmaceutical Development and Technology 22:3, pages 322-329.
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Krutika K. Sawant, Mitali H. Patel & Krishna Patel. (2016) Cefdinir nanosuspension for improved oral bioavailability by media milling technique: formulation, characterization and in vitro–in vivo evaluations. Drug Development and Industrial Pharmacy 42:5, pages 758-768.
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Shayana Gora, Gulam Mustafa, Jasjeet Kaur Sahni, Javed Ali & Sanjula Baboota. (2016) Nanosizing of valsartan by high pressure homogenization to produce dissolution enhanced nanosuspension: pharmacokinetics and pharmacodyanamic study. Drug Delivery 23:3, pages 930-940.
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Ibrahim Elsayed, Aly Ahmed Abdelbary & Ahmed Hassen Elshafeey. (2014) Nanosizing of a poorly soluble drug: technique optimization, factorial analysis, and pharmacokinetic study in healthy human volunteers. International Journal of Nanomedicine 9, pages 2943-2953.
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Hao Lou, Min Liu, Wen Qu, James Johnson, Ed. Brunson & Hassan Almoazen. (2014) The influence of sodium salts (iodide, chloride and sulfate) on the formation efficiency of sulfamerazine nanocrystals. Pharmaceutical Development and Technology 19:5, pages 548-555.
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Aly A. Abdelbary, Xiaoling Li, Mohamed El-Nabarawi, Abdelhalim Elassasy & Bhaskara Jasti. (2014) Comparison of nanomilling and coprecipitation on the enhancement of in vitro dissolution rate of poorly water-soluble model drug aripiprazole. Pharmaceutical Development and Technology 19:4, pages 491-500.
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Peng-Fei Yue, Yu Li, Jing Wan, Yong Wang, Ming Yang, Wei-Feng Zhu, Chang-Hong Wang & Hai-Long Yuan. (2013) Process optimization and evaluation of novel baicalin solid nanocrystals. International Journal of Nanomedicine 8, pages 2961-2973.
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Indrajit Ghosh, Daniel Schenck, Sonali Bose, Frances Liu & Michael Motto. (2013) Identification of critical process parameters and its interplay with nanosuspension formulation prepared by top down media milling technology – A QbD perspective. Pharmaceutical Development and Technology 18:3, pages 719-729.
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Xiaoli Qi, Dianrui Zhang, Xia Xu, Feifei Feng, Guijie Ren, Qianqian Chu, Qiang Zhang & Keli Tian. (2012) Oridonin nanosuspension was more effective than free oridonin on G2/M cell cycle arrest and apoptosis in the human pancreatic cancer PANC-1 cell line. International Journal of Nanomedicine 7, pages 1793-1804.
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Lan Wang, Yanli Hao, Nan Liu, Mingshu Ma, Zhe Yin & Xiaoning Zhang. (2012) Enhance the dissolution rate and oral bioavailability of pranlukast by preparing nanosuspensions with high-pressure homogenizing method. Drug Development and Industrial Pharmacy 38:11, pages 1381-1389.
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Yusuke Tanaka, Mitsugi Inkyo, Ryoko Yumoto, Junya Nagai, Mikihisa Takano & Shunji Nagata. (2012) Nanoparticulation of probucol, a poorly water-soluble drug, using a novel wet-milling process to improve in vitro dissolution and in vivo oral absorption. Drug Development and Industrial Pharmacy 38:8, pages 1015-1023.
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Cheng-Dong Hou, Jie-Xin Wang, Yuan Le, Hai-Kui Zou & Hong Zhao. (2012) Preparation of azithromycin nanosuspensions by reactive precipitation method. Drug Development and Industrial Pharmacy 38:7, pages 848-854.
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Anagha Bhakay, Maneesh Merwade, Ecevit Bilgili & Rajesh N. Dave. (2011) Novel aspects of wet milling for the production of microsuspensions and nanosuspensions of poorly water-soluble drugs. Drug Development and Industrial Pharmacy 37:8, pages 963-976.
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Zhen Zhang, Xiumei Zhang, Wei Xue, Yuna YangYang, Derong Xu, Yunxue Zhao & Haiyan Lou. (2010) Effects of oridonin nanosuspension on cell proliferation and apoptosis of human prostatic carcinoma PC-3 cell line. International Journal of Nanomedicine 5, pages 735-742.
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Yan Gao, Zhonggang Li, Min Sun, Houli Li, Chenyu Guo, Jing Cui, Aiguo Li, Fengliang Cao, Yanwei Xi, Hongxiang Lou & Guangxi Zhai. (2010) Preparation, characterization, pharmacokinetics, and tissue distribution of curcumin nanosuspension with TPGS as stabilizer. Drug Development and Industrial Pharmacy 36:10, pages 1225-1234.
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Seitaro Kamiya, Takurou Kurita, Atsuo Miyagishima & Masayuki Arakawa. (2009) Preparation of griseofulvin nanoparticle suspension by high-pressure homogenization and preservation of the suspension with saccharides and sugar alcohols. Drug Development and Industrial Pharmacy 35:8, pages 1022-1028.
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