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Research Article

Advancements in Dry Powder Delivery to the Lung

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Pages 948-959 | Published online: 20 Oct 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Gizem Rüya Topal, Burcu Devrim, Müjde Eryilmaz & Asuman Bozkir. (2018) Design of ciprofloxacin-loaded nano-and microcomposite particles for dry powder inhaler formulations: preparation, in vitro characterisation, and antimicrobial efficacy. Journal of Microencapsulation 35:6, pages 533-547.
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A. Kourmatzis, S. Cheng & H.-K. Chan. (2018) Airway geometry, airway flow, and particle measurement methods: implications on pulmonary drug delivery. Expert Opinion on Drug Delivery 15:3, pages 271-282.
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Biswadip Sinha & Biswajit Mukherjee. (2012) Development of an inhalation chamber and a dry powder inhaler device for administration of pulmonary medication in animal model. Drug Development and Industrial Pharmacy 38:2, pages 171-179.
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Justin Pennington, John Lena, Joseph Medendorp & Gary Ewing. (2011) A uHPLC-MS mathematical modeling approach to dry powder inhaler single agglomerate analysis. Drug Development and Industrial Pharmacy 37:10, pages 1208-1216.
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Basma M Ibrahim, Michael D Tsifansky, Yan Yang & Yoon Yeo. (2011) Challenges and advances in the development of inhalable drug formulations for cystic fibrosis lung disease. Expert Opinion on Drug Delivery 8:4, pages 451-466.
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Zhen Xu, HeidiM. Mansour & AnthonyJ. Hickey. (2011) Particle Interactions in Dry Powder Inhaler Unit Processes: A Review. Journal of Adhesion Science and Technology 25:4-5, pages 451-482.
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Articles from other publishers (48)

Shadi Yaqoubi, Mohaddese Sokuti, Sahand Mazloum-Ravasan, Kofi Asare-Addo, Hamed Hamishehkar & Ali Nokhodchi. (2024) Preparing dry powder inhalation formulation of salbutamol sulfate using an ultrasonic atomizer device. Journal of Aerosol Science 175, pages 106290.
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Mohit Kumar, Ayah R. Hilles, Samah Hamed Almurisi, Amit Bhatia & Syed Mahmood. (2023) Micro and nano-carriers-based pulmonary drug delivery system: Their current updates, challenges, and limitations – A review. JCIS Open 12, pages 100095.
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Sachin S. Gaikwad, Snehal R. Pathare, Mayur A. More, Nikita A. Waykhinde, Umesh D. Laddha, Kishor S. Salunkhe, Sanjay J. Kshirsagar, Sakshi S. Patil & Kuldeep H. Ramteke. (2023) Dry Powder Inhaler with the technical and practical obstacles, and forthcoming platform strategies. Journal of Controlled Release 355, pages 292-311.
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Moustafa M. Abdelaziz, Amr Hefnawy, Asem Anter, Menna M. Abdellatif, Mahmoud A.F. Khalil & Islam A. Khalil. (2023) Inhalable vancomycin-loaded lactose microparticles for treatment of MRSA pneumonia. Journal of Drug Delivery Science and Technology 80, pages 104150.
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M.H. Le Nguyen, M.S Naoum, C. Andre, L. Lethier, S. Limat, C. Fagnoni-Legat, Y. Guillaume & A.S. Gauthier. (2022) Physicochemical and microbiological stability of insulin eye drops in an artificial tear vehicle used in the treatment of refractory neurotrophic keratopathy. Journal Français d'Ophtalmologie 45:8, pages 860-871.
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Jiawei Wang, Xiangjun Kong, Linfeng Hu & Yuanjia Hu. (2022) Dry powder inhalers: A patent review. Journal of Drug Delivery Science and Technology 74, pages 103540.
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Moustafa M. Abdelaziz, Amr Hefnawy, Asem Anter, Menna M. Abdellatif, Mahmoud A.F. Khalil & Islam A. Khalil. (2022) Respirable spray dried vancomycin coated magnetic nanoparticles for localized lung delivery. International Journal of Pharmaceutics 611, pages 121318.
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Zejun Wang, Jinqiang Wang, Anna R. Kahkoska, John B. Buse & Zhen Gu. (2021) Developing Insulin Delivery Devices with Glucose Responsiveness. Trends in Pharmacological Sciences 42:1, pages 31-44.
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Vinit V. Agnihotri, Chandrakantsing V. Pardeshi & Sanjay J. Surana. 2021. Drug Delivery Devices and Therapeutic Systems. Drug Delivery Devices and Therapeutic Systems 213 245 .
Xue Jin, Ling Song, Chao-Chao Ma, Yan-Chun Zhang & Shui Yu. (2020) RETRACTED: Pulmonary route of administration is instrumental in developing therapeutic interventions against respiratory diseases. Saudi Pharmaceutical Journal 28:12, pages 1655-1665.
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Stefan Wanning, Richard Süverkrüp & Alf Lamprecht. (2020) Impact of excipient choice on the aerodynamic performance of inhalable spray-freeze-dried powders. International Journal of Pharmaceutics 586, pages 119564.
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Nagarjun Rangaraj, Sravanthi Reddy Pailla & Sunitha Sampathi. (2019) Insight into pulmonary drug delivery: Mechanism of drug deposition to device characterization and regulatory requirements. Pulmonary Pharmacology & Therapeutics 54, pages 1-21.
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Faezeh Khandouzi, Zahra Daman & Kambiz Gilani. (2017) Optimized particle engineering of fluticasone propionate and salmeterol xinafoate by spray drying technique for dry powder inhalation. Advanced Powder Technology 28:2, pages 534-542.
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Stefan Wanning, Richard Süverkrüp & Alf Lamprecht. (2017) Jet-vortex spray freeze drying for the production of inhalable lyophilisate powders. European Journal of Pharmaceutical Sciences 96, pages 1-7.
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Young H. Lim, Kristin M. Tiemann, David A. Hunstad, Mahmoud Elsabahy & Karen L. Wooley. (2016) Polymeric nanoparticles in development for treatment of pulmonary infectious diseases. WIREs Nanomedicine and Nanobiotechnology 8:6, pages 842-871.
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Thiago C Carvalho & Jason T McConville. (2016) The function and performance of aqueous aerosol devices for inhalation therapy. Journal of Pharmacy and Pharmacology 68:5, pages 556-578.
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Francesca Buttini, Irene Pasquali, Gaetano Brambilla, Diego Copelli, Massimiliano Dagli Alberi, Anna Giulia Balducci, Ruggero Bettini & Viviana Sisti. (2015) Multivariate Analysis of Effects of Asthmatic Patient Respiratory Profiles on the In Vitro Performance of a Reservoir Multidose and a Capsule-Based Dry Powder Inhaler. Pharmaceutical Research 33:3, pages 701-715.
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Kalidhindi Rama Satyanarayana Raju, Nilesh S. Ambhore, Shashank Mulukutla, Saurabh Gupta, Vishakantha Murthy, M.N. Kiran Kumar, Subba Rao V. Madhunapantula, Gowthamarajan Kuppuswamy & Kannan Elango. (2016) Salicylic acid derivatives as potential anti asthmatic agents using disease responsive drug delivery system for prophylactic therapy of allergic asthma. Medical Hypotheses 87, pages 75-79.
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Jolyon Mitchell. 2016. Developing Drug Products in an Aging Society. Developing Drug Products in an Aging Society 331 382 .
Simone R. Carvalho, Alan B. Watts, Jay I. Peters & Robert O. WilliamsIIIIII. 2015. Pulmonary Drug Delivery. Pulmonary Drug Delivery 35 62 .
Kai Berkenfeld, Alf Lamprecht & Jason T. McConville. (2015) Devices for Dry Powder Drug Delivery to the Lung. AAPS PharmSciTech 16:3, pages 479-490.
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Zahra Daman, Kambiz Gilani, Abdolhossein Rouholamini Najafabadi, Hamid Reza Eftekhari & Mohammad Ali Barghi. (2014) Formulation of inhalable lipid-based salbutamol sulfate microparticles by spray drying technique. DARU Journal of Pharmaceutical Sciences 22:1.
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Anne Marie Healy, Maria Inês Amaro, Krzysztof J. Paluch & Lidia Tajber. (2014) Dry powders for oral inhalation free of lactose carrier particles. Advanced Drug Delivery Reviews 75, pages 32-52.
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Mahavir Chougule, Rakesh Tekade, Peter Hoffmann, Deepak Bhatia, Vijaykumar Sutariya & Yashwant Pathak. 2014. Biointeractions of Nanomaterials. Biointeractions of Nanomaterials 225 248 .
Eike Cordts & Hartwig Steckel. (2014) Formulation considerations for dry powder inhalers. Therapeutic Delivery 5:6, pages 675-689.
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Sarah Claus, Claudius Weiler, Joerg Schiewe & Wolfgang Friess. (2014) How can we bring high drug doses to the lung?. European Journal of Pharmaceutics and Biopharmaceutics 86:1, pages 1-6.
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Beth L. Laube & Myrna B. Dolovich. 2014. Middleton's Allergy. Middleton's Allergy 1066 1082 .
Ju Du, Ping Du & Hugh DC Smyth. (2013) Hydrogels for controlled pulmonary delivery. Therapeutic Delivery 4:10, pages 1293-1305.
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Samantha A. Meenach, Kimberly W. Anderson, J. Zach Hilt, Ronald C. McGarry & Heidi M. Mansour. (2013) Characterization and aerosol dispersion performance of advanced spray-dried chemotherapeutic PEGylated phospholipid particles for dry powder inhalation delivery in lung cancer. European Journal of Pharmaceutical Sciences 49:4, pages 699-711.
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Renishkumar DelvadiaMichael HindleP. Worth LongestPeter R. Byron. (2013) In Vitro Tests for Aerosol Deposition II: IVIVCs for Different Dry Powder Inhalers in Normal Adults . Journal of Aerosol Medicine and Pulmonary Drug Delivery 26:3, pages 138-144.
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Yoen-Ju Son, P. Worth Longest, Geng Tian & Michael Hindle. (2013) Evaluation and modification of commercial dry powder inhalers for the aerosolization of a submicrometer excipient enhanced growth (EEG) formulation. European Journal of Pharmaceutical Sciences 49:3, pages 390-399.
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Gaia Colombo, Chiara Parlati & Paola Russo. 2013. Inhalation Drug Delivery. Inhalation Drug Delivery 145 168 .
S. Stegemann, S. Kopp, G. Borchard, V.P. Shah, S. Senel, R. Dubey, N. Urbanetz, M. Cittero, A. Schoubben, C. Hippchen, D. Cade, A. Fuglsang, J. Morais, L. Borgström, F. Farshi, K.-H. Seyfang, R. Hermann, A. van de Putte, I. Klebovich & A. Hincal. (2013) Developing and advancing dry powder inhalation towards enhanced therapeutics. European Journal of Pharmaceutical Sciences 48:1-2, pages 181-194.
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Prinda Wanakule, Gary W. Liu, Asha T. Fleury & Krishnendu Roy. (2012) Nano-inside-micro: Disease-responsive microgels with encapsulated nanoparticles for intracellular drug delivery to the deep lung. Journal of Controlled Release 162:2, pages 429-437.
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Dhrumil Upadhyay, Santo Scalia, Robert Vogel, Nial Wheate, Rania O. Salama, Paul M. Young, Daniela Traini & Wojciech Chrzanowski. (2012) Magnetised Thermo Responsive Lipid Vehicles for Targeted and Controlled Lung Drug Delivery. Pharmaceutical Research 29:9, pages 2456-2467.
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Lev Ruzer & Naomi HarleyStephen Marek, Hugh Smyth, Lucila Garcia-Contreras, Daniel Cooney, Robert Garmise, Latarsha Jones & Anthony Hickey. 2012. Aerosols Handbook. Aerosols Handbook 1 30 .
Francesca Buttini, Paolo Colombo, Alessandra Rossi, Fabio Sonvico & Gaia Colombo. (2012) Particles and powders: Tools of innovation for non-invasive drug administration. Journal of Controlled Release 161:2, pages 693-702.
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Xi Zhang, Yingliang Ma, Liqiang Zhang, Jingxu Zhu & Fang Jin. (2012) The development of a novel dry powder inhaler. International Journal of Pharmaceutics 431:1-2, pages 45-52.
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Shinjiro Miyawaki, Merryn H. Tawhai, Eric A. Hoffman & Ching-Long Lin. (2012) Effect of Carrier Gas Properties on Aerosol Distribution in a CT-based Human Airway Numerical Model. Annals of Biomedical Engineering 40:7, pages 1495-1507.
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Nazrul Islam & Matthew J. Cleary. (2012) Developing an efficient and reliable dry powder inhaler for pulmonary drug delivery – A review for multidisciplinary researchers. Medical Engineering & Physics 34:4, pages 409-427.
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Martin J Donovan, Aileen Gibbons, Matthew J Herpin, Stephen Marek, Shayna L McGill & Hugh DC Smyth. (2011) Novel dry powder inhaler particle-dispersion systems. Therapeutic Delivery 2:10, pages 1295-1311.
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Myrna B Dolovich & Rajiv Dhand. (2011) Aerosol drug delivery: developments in device design and clinical use. The Lancet 377:9770, pages 1032-1045.
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Yu Zhang, Xiaoli Wang, Xia Lin, Xiaoliang Liu, Bin Tian & Xing Tang. (2010) High azithromycin loading powders for inhalation and their in vivo evaluation in rats. International Journal of Pharmaceutics 395:1-2, pages 205-214.
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Jasper Vollenbroek, Gerald A. Hebbink, Susanne Ziffels & Hartwig Steckel. (2010) Determination of low levels of amorphous content in inhalation grade lactose by moisture sorption isotherms. International Journal of Pharmaceutics 395:1-2, pages 62-70.
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Chikamasa Yamashita. (2009) Development of Otsuka dry powder inhalation system using technology of freeze-drying. Drug Delivery System 24:5, pages 468-476.
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Eva Horn Moeller & Lene Jorgensen. (2008) Alternative routes of administration for systemic delivery of protein pharmaceuticals. Drug Discovery Today: Technologies 5:2-3, pages e89-e94.
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