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Research Article

Oral bioavailability enhancement of flubendazole by developing nanofibrous solid dosage forms

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Pages 1126-1133 | Received 12 Aug 2016, Accepted 19 Feb 2017, Published online: 08 Mar 2017

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Ahmed S. Kamel, Soha M. El-Masry, Haidy Abbas, Fatma Mkh Ibrahim, Hager S. Zoghroban & Gamal M. El Maghraby. (2023) Nano-crystallization of flubendazole for enhanced dissolution rate and improved in vivo efficacy against Trichinella spiralis. Pharmaceutical Development and Technology 28:6, pages 571-583.
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Xin Che, Juan Xue, Jianfeng Zhang, Xiangbo Yang & Lihong Wang. (2020) One-step preparation of ibuprofen fast- and sustained-release formulation by electrospinning with improved efficacy and reduced side effect. Pharmaceutical Development and Technology 25:6, pages 659-665.
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Weiqin Wang, Changchang Cui, Mengying Li, Zhenhai Zhang & Huixia Lv. (2017) Study of a novel disintegrable oleanolic acid-polyvinylpolypyrrolidone solid dispersion. Drug Development and Industrial Pharmacy 43:7, pages 1178-1185.
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Articles from other publishers (16)

Nikita A. Vasilev, Alexander P. Voronin, Artem O. Surov & German L. Perlovich. (2023) Influence of Co-amorphization on the Physical Stability and Dissolution Performance of an Anthelmintic Drug Flubendazole. Molecular Pharmaceutics 20:3, pages 1657-1669.
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Stefania Marano, Manish Ghimire, Shahrzad Missaghi, Ali Rajabi-Siahboomi, Duncan Q. M. Craig & Susan A. Barker. (2023) Development of Robust Tablet Formulations with Enhanced Drug Dissolution Profiles from Centrifugally-Spun Micro-Fibrous Solid Dispersions of Itraconazole, a BCS Class II Drug. Pharmaceutics 15:3, pages 802.
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Ioannis Partheniadis, Konstantina Athanasiou, Ivo Laidmäe, Jyrki Heinämäki & Ioannis Nikolakakis. (2022) Physicomechanical characterization and tablet compression of theophylline nanofibrous mats prepared by conventional and ultrasound enhanced electrospinning. International Journal of Pharmaceutics 616, pages 121558.
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João M.C. de Assis, Eduardo J. Barbosa, Vinícius D.N. Bezzon, Felipe R. Lourenço, Flavio M.S. Carvalho, J.R. Matos, Nadia Araci Bou-Chacra, Chris J. Benmore, Stephen R. Byrn, Fanny N. Costa & Gabriel L.B. de Araujo. (2022) Hot-melt extrudability of amorphous solid dispersions of flubendazole-copovidone: An exploratory study of the effect of drug loading and the balance of adjuvants on extrudability and dissolution. International Journal of Pharmaceutics 614, pages 121456.
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Taha Umair Wani, Taseen Aamir Wani, Anjum Hamid Rather, Rumysa Saleem Khan, Mushtaq A. Beigh & Faheem A. Sheikh. 2022. Electrospun Nanofibers. Electrospun Nanofibers 331 349 .
Daliana Minda, Alexandra Mioc, Christian Banciu, Codruța Soica, Roxana Racoviceanu, Marius Mioc, Ioana Macasoi, Stefana Avram, Adrian Voicu, Andrei Motoc & Cristina Trandafirescu. (2021) Cyclodextrin Dispersion of Mebendazole and Flubendazole Improves In Vitro Antiproliferative Activity. Processes 9:12, pages 2185.
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Megumi Nishitani Yukuyama, Kelly Ishida, Gabriel Lima Barros de Araujo, Cristina de Castro Spadari, Aline de Souza, Raimar Löbenberg, Mirla Anali Bazán Henostroza, Beatriz Rabelo Folchini, Camilla Midori Peroni, Maria Christina Camasmie Peters, Isabela Fernandes de Oliveira, Mariana Yasue Saito Miyagi & Nádia Araci Bou-Chacra. (2021) Rational design of oral flubendazole-loaded nanoemulsion for brain delivery in cryptococcosis. Colloids and Surfaces A: Physicochemical and Engineering Aspects 630, pages 127631.
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Krisztina Kiss, Panna Vass, Attila Farkas, Edit Hirsch, Edina Szabó, Gábor Mező, Zsombor Kristóf Nagy & György Marosi. (2020) A solid doxycycline HP-β-CD formulation for reconstitution (i.v. bolus) prepared by scaled-up electrospinning. International Journal of Pharmaceutics 586, pages 119539.
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Panna Vass, Edina Szabó, András Domokos, Edit Hirsch, Dorián Galata, Balázs Farkas, Balázs Démuth, Sune K. Andersen, Tamás Vigh, Geert Verreck, György Marosi & Zsombor K. Nagy. (2019) Scale‐up of electrospinning technology: Applications in the pharmaceutical industry. WIREs Nanomedicine and Nanobiotechnology 12:4.
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Ahmad Ziaee, Stephen O'Dea, Aoise Howard-Hildige, Luis Padrela, Catherine Potter, Javed Iqbal, Ahmad B. Albadarin, Gavin Walker & Emmet J. O'Reilly. (2019) Amorphous solid dispersion of ibuprofen: A comparative study on the effect of solution based techniques. International Journal of Pharmaceutics 572, pages 118816.
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Fuat Topuz & Tamer Uyar. (2018) Electrospinning of Cyclodextrin Functional Nanofibers for Drug Delivery Applications. Pharmaceutics 11:1, pages 6.
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Gergő Fülöp, Attila Balogh, Balazs Farkas, Attila Farkas, Bence Szabó, Balázs Démuth, Enikő Borbás, Zsombor Kristóf Nagy & György Marosi. (2018) Homogenization of Amorphous Solid Dispersions Prepared by Electrospinning in Low-Dose Tablet Formulation. Pharmaceutics 10:3, pages 114.
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Milena Ignatova, Nevena Manolova, Iliya Rashkov & Nadya Markova. (2018) Antibacterial and antioxidant electrospun materials from poly(3-hydroxybutyrate) and polyvinylpyrrolidone containing caffeic acid phenethyl ester – “in” and “on” strategies for enhanced solubility. International Journal of Pharmaceutics 545:1-2, pages 342-356.
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Francisca Acevedo, Jeyson Hermosilla, Claudia Sanhueza, Barbara Mora-Lagos, Irma Fuentes, Mónica Rubilar, Angel Concheiro & Carmen Alvarez-Lorenzo. (2018) Gallic acid loaded PEO-core/zein-shell nanofibers for chemopreventive action on gallbladder cancer cells. European Journal of Pharmaceutical Sciences 119, pages 49-61.
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Stefano Sainas, Franco Dosio, Donatella Boschi & Marco L. Lolli. 2018. Neglected Diseases: Extensive Space for Modern Drug Discovery. Neglected Diseases: Extensive Space for Modern Drug Discovery 1 38 .
Peng Wen, Yan Wen, Xiao Huang, Min-Hua Zong & Hong Wu. (2017) Preparation and Characterization of Protein-Loaded Electrospun Fiber Mat and Its Release Kinetics. Journal of Agricultural and Food Chemistry 65:23, pages 4786-4796.
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