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Drug Development and Industrial Pharmacy Volume 43, 2017 - Issue 10
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Research Article

A novel pH-responsive hydrogel-based on calcium alginate engineered by the previous formation of polyelectrolyte complexes (PECs) intended to vaginal administration

Natália Noronha FerreiraSchool of Pharmaceutical Sciences, São Paulo State University, UNESP, São Paulo, Brazil;
,
Taciane Alvarenga PerezSchool of Pharmaceutical Sciences, São Paulo State University, UNESP, São Paulo, Brazil;
,
Liliane Neves PedreiroSchool of Pharmaceutical Sciences, São Paulo State University, UNESP, São Paulo, Brazil;
,
Fabíola Garavello PrezottiSchool of Pharmaceutical Sciences, São Paulo State University, UNESP, São Paulo, Brazil;
,
Fernanda Isadora BoniSchool of Pharmaceutical Sciences, São Paulo State University, UNESP, São Paulo, Brazil;
,
Valéria Maria de Oliveira CardosoSchool of Pharmaceutical Sciences, São Paulo State University, UNESP, São Paulo, Brazil;
,
Tiago VenâncioDepartment of Chemistry, Federal University of São Carlos, São Carlos, Brazil
&
Maria Palmira Daflon GremiãoSchool of Pharmaceutical Sciences, São Paulo State University, UNESP, São Paulo, Brazil; Correspondence[email protected]
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Pages 1656-1668 | Received 16 Jan 2017, Accepted 03 May 2017, Published online: 25 May 2017

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Liliane Neves Pedreiro, Fernanda Isadora Boni, Beatriz Stringhetti Ferreira Cury, Natália Noronha Ferreira & Maria Palmira Daflon Gremião. (2022) Solid dispersions based on chitosan/hypromellose phthalate blends to modulate pharmaceutical properties of zidovudine. Pharmaceutical Development and Technology 27:5, pages 615-624.
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Articles from other publishers (23)

Ke-Han Shen, Ting-Hsiang Chiu, Kuang-Chih Teng, Jiashing Yu & Yi-Cheun Yeh. (2023) Fabrication of triple-crosslinked gelatin/alginate hydrogels for controlled release applications. International Journal of Biological Macromolecules 250, pages 126133.
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Mariana Rillo Sato, João Augusto Oshiro-Junior, Camila Fernanda Rodero, Fernanda Isadora Boni, Victor Hugo Sousa Araújo, Taís Maria Bauab, Dean Nicholas, John Francis Callan & Marlus Chorilli. (2023) Enhancing Antifungal Treatment of Candida albicans with Hypericin-Loaded Nanostructured Lipid Carriers in Hydrogels: Characterization, In Vitro, and In Vivo Photodynamic Evaluation. Pharmaceuticals 16:8, pages 1094.
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Sadikalmahdi Abdella, Fatima Abid, Souha H. Youssef, Sangseo Kim, Franklin Afinjuomo, Constance Malinga, Yunmei Song & Sanjay Garg. (2023) pH and its applications in targeted drug delivery. Drug Discovery Today 28:1, pages 103414.
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Kaan Emre Balan, Cihangir Boztepe & Asım Künkül. (2022) Modeling the effect of physical crosslinking degree of pH and temperature responsive poly(NIPAAm-co-VSA)/alginate IPN hydrogels on drug release behavior. Journal of Drug Delivery Science and Technology 75, pages 103671.
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Mohammad A. S. Abourehab, Rahul R. Rajendran, Anshul Singh, Sheersha Pramanik, Prachi Shrivastav, Mohammad Javed Ansari, Ravi Manne, Larissa Souza Amaral & A. Deepak. (2022) Alginate as a Promising Biopolymer in Drug Delivery and Wound Healing: A Review of the State-of-the-Art. International Journal of Molecular Sciences 23:16, pages 9035.
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Gabriel Davi Marena, Matheus Aparecido dos Santos Ramos, Gabriela Corrêa Carvalho, Laura Caminitti de Lima, André Luiz Carneiro Soares do Nascimento, Rafael Miguel Sábio, Camila Fernanda Rodero, Larissa Spósito, Tais Maria Bauab & Marlus Chorilli. (2022) Development and characterization of an amphotericin B - loaded nanoemulsion applied to Candida auris biofilms control. Journal of Drug Delivery Science and Technology 74, pages 103566.
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Pierre P. D. Kondiah, Thankhoe A. Rants’o, Sifiso S. Makhathini, Sipho Mdanda & Yahya E. Choonara. (2022) An Oral 3D Printed PLGA-Tocopherol PEG Succinate Nanocomposite Hydrogel for High-Dose Methotrexate Delivery in Maintenance Chemotherapy. Biomedicines 10:7, pages 1470.
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Fayaz Ali, Imran Khan, Jianmin Chen, Kalsoom Akhtar, Esraa M. Bakhsh & Sher Bahadar Khan. (2022) Emerging Fabrication Strategies of Hydrogels and Its Applications. Gels 8:4, pages 205.
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Dmitrii Iudin, Marina Vasilieva, Elena Knyazeva, Viktor Korzhikov-Vlakh, Elena Demyanova, Antonina Lavrentieva, Yury Skorik & Evgenia Korzhikova-Vlakh. (2022) Hybrid Nanoparticles and Composite Hydrogel Systems for Delivery of Peptide Antibiotics. International Journal of Molecular Sciences 23:5, pages 2771.
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Valéria Maria de Oliveira Cardoso, Leonardo Miziara Barboza Ferreira, Edson José Comparetti, Isabella Sampaio, Natália Noronha Ferreira, Renata Rank Miranda & Valtencir Zucolotto. 2022. Stimuli-Responsive Nanocarriers. Stimuli-Responsive Nanocarriers 87 117 .
Rogelio Rodríguez-Rodríguez, Hugo Espinosa-Andrews & Zaira Yunuen García-Carvajal. 2022. Functional Biomaterials. Functional Biomaterials 75 103 .
Payal Kesharwani, Akansha Bisht, Amit Alexander, Vivek Dave & Swapnil Sharma. (2021) Biomedical applications of hydrogels in drug delivery system: An update. Journal of Drug Delivery Science and Technology 66, pages 102914.
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Ricardo I. Castro, Luis Morales-Quintana, Nancy Alvarado, Luis Guzmán, Oscar Forero-Doria, Felipe Valenzuela-Riffo & V. Felipe Laurie. (2021) Design and Optimization of a Self-Assembling Complex Based on Microencapsulated Calcium Alginate and Glutathione (CAG) Using Response Surface Methodology. Polymers 13:13, pages 2080.
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Fernanda Isadora Boni, Beatriz S. F. Cury, Natália Noronha Ferreira & Maria Palmira Daflon Gremião. (2021) Ionic Cross-Linking as a Strategy to Modulate the Properties of Oral Mucoadhesive Microparticles Based on Polysaccharide Blends. Pharmaceutics 13:3, pages 407.
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Aline Martins dos Santos, Suzana Gonçalves Carvalho, Victor Hugo Sousa Araujo, Gabriela Corrêa Carvalho, Maria Palmira Daflon Gremião & Marlus Chorilli. (2020) Recent advances in hydrogels as strategy for drug delivery intended to vaginal infections. International Journal of Pharmaceutics 590, pages 119867.
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Sheila Maiz-Fernández, Leyre Pérez-Álvarez, Leire Ruiz-Rubio, Jose Luis Vilas-Vilela & Senentxu Lanceros-Mendez. (2020) Polysaccharide-Based In Situ Self-Healing Hydrogels for Tissue Engineering Applications. Polymers 12:10, pages 2261.
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Francesca Damiani Victorelli, Valéria Maria de Oliveira Cardoso, Natália Noronha Ferreira, Giovana Maria Fioramonti Calixto, Carla Raquel Fontana, Fátima Baltazar, Maria Palmira Daflon Gremião & Marlus Chorilli. (2020) Chick embryo chorioallantoic membrane as a suitable in vivo model to evaluate drug delivery systems for cancer treatment: A review. European Journal of Pharmaceutics and Biopharmaceutics 153, pages 273-284.
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O. Valdés, A. Marican, F. Avila‐Salas, R.I. Castro, Y. Mirabal, J. Amalraj, D. Abril, E.F. Durán‐Lara & L.S. Santos. (2019) Simple approach for cleaning up 2,4,6‐trichloroanisole from alcoholic‐beverage‐reconstituted solutions using polymeric materials. Australian Journal of Grape and Wine Research 25:3, pages 327-337.
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Natália Noronha Ferreira, Bruno Leonardo Caetano, Fernanda Isadora Boni, Flávia Sousa, Marina Magnani, Bruno Sarmento, Beatriz Stringhetti Ferreira Cury & Maria Palmira Daflon Gremião. (2019) Alginate-Based Delivery Systems for Bevacizumab Local Therapy: In Vitro Structural Features and Release Properties. Journal of Pharmaceutical Sciences 108:4, pages 1559-1568.
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Ozan Erol, Aishwarya Pantula, Wangqu Liu & David H. Gracias. (2019) Transformer Hydrogels: A Review. Advanced Materials Technologies 4:4, pages 1900043.
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Mona Fathi, Sohrab Kazemi, Farbod Zahedi, Mohamad Reza Shiran & Ali Akbar Moghadamnia. (2018) Comparison of oral bioavailability of acetaminophen tablets, capsules and effervescent dosage forms in healthy volunteers. Current Issues in Pharmacy and Medical Sciences 31:1, pages 5-9.
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N.N. Ferreira, L.M.B. Ferreira, V.M.O. Cardoso, F.I. Boni, A.L.R. Souza & M.P.D. Gremião. (2018) Recent advances in smart hydrogels for biomedical applications: From self-assembly to functional approaches. European Polymer Journal 99, pages 117-133.
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He-Lin Xu, Jie Xu, Bi-Xin Shen, Si-Si Zhang, Bing-Hui Jin, Qun-Yan Zhu, De-Li ZhuGe, Xue-Qing Wu, Jian Xiao & Ying-Zheng Zhao. (2017) Dual Regulations of Thermosensitive Heparin–Poloxamer Hydrogel Using ε-Polylysine: Bioadhesivity and Controlled KGF Release for Enhancing Wound Healing of Endometrial Injury. ACS Applied Materials & Interfaces 9:35, pages 29580-29594.
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