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Research Articles

Effect of different molecular weight PLGA on flurbiprofen nanoparticles: formulation, characterization, cytotoxicity, and in vivo anti-inflammatory effect by using HET-CAM assay

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Pages 682-695 | Received 13 Nov 2019, Accepted 07 Apr 2020, Published online: 23 Apr 2020

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Basak Simitcioglu, Isik Didem Karagoz, Sibel Ilbasmis-Tamer & Ugur Tamer. (2022) Effect of different molecular weight and terminal group PLGA on docetaxel nanoparticles: characterization and cytotoxic activity of castration-resistant prostate cancer cells. Pharmaceutical Development and Technology 27:7, pages 794-804.
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Mariana Domingues Bianchin, Germano Prebianca, Maira Frielink Immich, Mário Lettieri Teixeira, Mariana Colombo, Leticia Scherer Koester, Bibiana Verlindo de Araújo, Fernanda Poletto & Irene Clemes Külkamp-Guerreiro. (2021) Monoolein-based nanoparticles containing indinavir: a taste-masked drug delivery system. Drug Development and Industrial Pharmacy 47:1, pages 83-91.
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XiaoFei Tang, Huaiying Qin, XiaoYun Zhang, Haiyun Yang, Jianhua Yang, Ping Chen, Yinli Jin & Lu Yang. (2023) Design, optimization, and evaluation for a long-time-released transdermal microneedle delivery system containing estradiol. Drug Delivery and Translational Research.
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Jiajia Ye, Wen Liang, Lang Wu, Rongjuan Guo, Wei Wu, Deqin Yang & Liang Chen. (2023) Antimicrobial effect of Streptococcus salivarius outer membrane-coated nanocomplexes against Candida albicans and oral candidiasis. Materials & Design 233, pages 112177.
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Evrim Yenilmez, Ahmet Alper Öztürk & Ebru Başaran. (2023) Preparation and In vitro, Ex vivo Evaluation of Benzidamine Hydrochloride Loaded Fast Dissolving Oral Strip Formulations: Treatment of Oral Mucositis Due to Side Effects of Chemotherapy and Radiotherapy. Letters in Drug Design & Discovery 20:8, pages 1147-1157.
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Ümit Haydar Erol, Enes Güncüm & Nuran Işıklan. (2023) Development of chitosan-graphene oxide blend nanoparticles for controlled flurbiprofen delivery. International Journal of Biological Macromolecules 246, pages 125627.
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Muhammad Suhail, Chih-Wun Fang, I-Hui Chiu, Arshad Khan, Yi-Chun Wu, I-Ling Lin, Ming-Jun Tsai & Pao-Chu Wu. (2023) Synthesis and Evaluation of Alginate-Based Nanogels as Sustained Drug Carriers for Caffeine. ACS Omega 8:26, pages 23991-24002.
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Hülya Tuba Kıyan, Ayca Üvez, Merve Erkisa, Elif İlkay Ikitimur-Armutak, Nadim Yılmazer, Osman Behzat Burak Esener, Deniz Erol Kutucu, Savaş Üstünova, Engin Ulukaya, A. Alper Öztürk & Ebru Gürel-Gürevin. (2023) A Comparative Study on In vitro Anti-cancer and In vivo Anti-angiogenic Effects of TRPC Blockers Pyr-3 and SKF-96365. Letters in Drug Design & Discovery 20:7, pages 957-964.
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A.A. Öztürk, T. Çevikelli, E.K. Tilki, U.M. Güven & H.T. Kıyan. (2023) Ketorolac Tromethamine Loaded Nano-Spray Dried Nanoparticles: Preparation, Characterization, Cell Viability, COL1A1 Gene Simulation and Determination of Anti-inflammatory Activity by In vivo HET-CAM Assay. Current Drug Delivery 20:6, pages 830-840.
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Beril Kurban, Tuğba Tuncel, Şennur Görgülü, Fatih Kar, Alper Öztürk & Temel Özek. (2023) Elemi essential oil nanocapsulated drug ameliorates lung cancer via oxidative stress, apoptosis and inflammation pathway. Journal of Cellular and Molecular Medicine 27:13, pages 1887-1899.
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A. Alper Öztürk, Ebru Başaran, Behiye Şenel, Müzeyyen Demirel & Şenay Sarıca. (2023) Synthesis, characterization, antioxidant activity of Quercetin, Rutin and Quercetin-Rutin incorporated β-cyclodextrin inclusion complexes and determination of their activity in NIH-3T3, MDA-MB-231 and A549 cell lines. Journal of Molecular Structure 1282, pages 135169.
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Berna Kaval, Fatma Dilara Şen, Kemal Kaya Batmaz, Meliha Ekinci & A. Alper Öztürk. (2023) Latest research about active pharmaceutical ingredient loaded Poly Lactic Acid-co-Glycolic Acid (PLGA) based drug delivery system in Türkiye. European Journal of Life Sciences 1:3, pages 127-139.
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Sedat Ünal, Gamze Varan, Juan M Benito, Yeşim Aktaş & Erem Bilensoy. (2023) Insight into oral amphiphilic cyclodextrin nanoparticles for colorectal cancer: comprehensive mathematical model of drug release kinetic studies and antitumoral efficacy in 3D spheroid colon tumors. Beilstein Journal of Organic Chemistry 19, pages 139-157.
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Lala Baghirova, Elif Kaya Tilki & A. Alper Öztürk. (2023) Evaluation of Cell Proliferation and Wound Healing Effects of Vitamin A Palmitate-Loaded PLGA/Chitosan-Coated PLGA Nanoparticles: Preparation, Characterization, Release, and Release Kinetics. ACS Omega 8:2, pages 2658-2668.
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Cuiting Hao, Xi Guo, Zhenghan Dong, Qiong Guo & Wei Shi. (2023) Zymolytic grain extract facilitates the conversion of liver tumor cells to hepatocyte-like cells through hepatocyte nuclear factors. Biomedicine & Pharmacotherapy 157, pages 114029.
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Kimberly S. Butler, C. Jeffrey Brinker & Hon Sing Leong. (2022) Bridging the In Vitro to In Vivo gap: Using the Chick Embryo Model to Accelerate Nanoparticle Validation and Qualification for In Vivo studies . ACS Nano 16:12, pages 19626-19650.
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Luting Weng, Lang Wu, Rongjuan Guo, Jiajia Ye, Wen Liang, Wei Wu, Liang Chen & Deqin Yang. (2022) Lactobacillus cell envelope-coated nanoparticles for antibiotic delivery against cariogenic biofilm and dental caries. Journal of Nanobiotechnology 20:1.
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Cigdem Cetin Aluc, Bahar Gok, Serda Kecel-Gunduz & Yasemin Budama-Kilinc. (2022) Glycyrrhizic acid Poly(D,L-lactide-co-glycolide) nanoparticles: anti-aging cosmeceutical formulation for topical applications. PeerJ 10, pages e14139.
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Muhammad Suhail, Chuan-Ming Shih, Jia-Yu Liu, Wan-Chu Hsieh, Yu-Wen Lin & Pao-Chu Wu. (2022) In-vitro and in-vivo evaluation of biocompatible polymeric microgels for pH- driven delivery of Ketorolac tromethamine. International Journal of Pharmaceutics 626, pages 122194.
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Muhammad Suhail, Chuan-Ming Shih, Jia-Yu Liu, Wan-Chu Hsieh, Yu-Wen Lin, I-Ling Lin & Pao-Chu Wu. (2022) Synthesis of glutamic acid/polyvinyl alcohol based hydrogels for controlled drug release: In-vitro characterization and in-vivo evaluation. Journal of Drug Delivery Science and Technology 75, pages 103715.
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Meliha Ekinci, A. Alper Öztürk, Ralph Santos-Oliveira & Derya İlem-Özdemir. (2022) The use of Lamivudine-loaded PLGA nanoparticles in the diagnosis of lung cancer: Preparation, characterization, radiolabeling with 99mTc and cell binding. Journal of Drug Delivery Science and Technology 69, pages 103139.
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A. Alper Öztürk & Cordin Arpagaus. (2021) Nano Spray-Dried Drugs for Oral Administration: A Review. ASSAY and Drug Development Technologies 19:7, pages 412-441.
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Victoria L. Messerschmidt, Uday Chintapula, Aneetta E. Kuriakose, Samantha Laboy, Thuy Thi Dang Truong, LeNaiya A. Kydd, Justyn Jaworski, Zui Pan, Hesham Sadek, Kytai T. Nguyen & Juhyun Lee. (2021) Notch Intracellular Domain Plasmid Delivery via Poly(Lactic-Co-Glycolic Acid) Nanoparticles to Upregulate Notch Pathway Molecules. Frontiers in Cardiovascular Medicine 8.
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Lidia Verano Naranjo, Cristina Cejudo Bastante, Lourdes Casas Cardoso, Casimiro Mantell Serrano & Enrique José Martínez de la Ossa Fernández. (2021) Supercritical Impregnation of Ketoprofen into Polylactic Acid for Biomedical Application: Analysis and Modeling of the Release Kinetic. Polymers 13:12, pages 1982.
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A. Alper Öztürkİrem NamlıAbdurrahman Aygül. (2021) Cefaclor Monohydrate-Loaded Colon-Targeted Nanoparticles for Use in COVID-19 Dependent Coinfections and Intestinal Symptoms: Formulation, Characterization, Release Kinetics, and Antimicrobial Activity. ASSAY and Drug Development Technologies 19:3, pages 156-175.
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Christian Grune, Clara Zens, Anna Czapka, Karl Scheuer, Jana Thamm, Stephanie Hoeppener, Klaus D. Jandt, Oliver Werz, Ute Neugebauer & Dagmar Fischer. (2021) Sustainable preparation of anti-inflammatory atorvastatin PLGA nanoparticles. International Journal of Pharmaceutics 599, pages 120404.
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