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Drug Development and Industrial Pharmacy Volume 46, 2020 - Issue 7
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Research Articles

Microneedle ocular patch: fabrication, characterization, and ex-vivo evaluation using pilocarpine as model drug

Girdhari RoyDepartment of Pharmacy, Birla Institute of Technology and Science (BITS) Pilani, Hyderabad, India; View further author information
,
Rohini Devi GaligamaDepartment of Pharmacy, Birla Institute of Technology and Science (BITS) Pilani, Hyderabad, India; View further author information
,
Veda Suresh ThoratDepartment of Pharmacy, Birla Institute of Technology and Science (BITS) Pilani, Hyderabad, India; View further author information
,
Prashant GargTej Kohli Cornea Institute, KAR Campus, L. V. Prasad Eye Institute, Hyderabad, IndiaView further author information
&
Venkata Vamsi Krishna VenugantiDepartment of Pharmacy, Birla Institute of Technology and Science (BITS) Pilani, Hyderabad, India; Correspondence[email protected]
ORCID Iconhttp://orcid.org/0000-0001-9686-9525View further author information
ORCID Icon
Pages 1114-1122 | Received 24 Feb 2020, Accepted 13 May 2020, Published online: 11 Jun 2020

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Keisham Nelson Mangang, Pragati Thakran, Jitu Halder, Kuldeep Singh Yadav, Goutam Ghosh, Deepak Pradhan, Goutam Rath & Vineet Kumar Rai. (2023) PVP-microneedle array for drug delivery: mechanical insight, biodegradation, and recent advances. Journal of Biomaterials Science, Polymer Edition 34:7, pages 986-1017.
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Axel Kattar, Angel Concheiro & Carmen Alvarez-Lorenzo. (2021) Diabetic eye: associated diseases, drugs in clinic, and role of self-assembled carriers in topical treatment. Expert Opinion on Drug Delivery 18:11, pages 1589-1607.
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Articles from other publishers (25)

Chukwuebuka Emmanuel Umeyor, Varsha Shelke, Apurva Pol, Prafull Kolekar, Sarika Jadhav, Nikita Tiwari, Ankita Anure, Abhit Nayak, Ghanshamdas Bairagi, Aniket Agale, Vaishnavi Raut, Sumedh Bahadure, Aniruddha Chaudhari & Vandana B. Patravale. (2023) Biomimetic microneedles: exploring the recent advances on a microfabricated system for precision delivery of drugs, peptides, and proteins. Future Journal of Pharmaceutical Sciences 9:1.
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Katie Glover, Deepakkumar Mishra, Shilpkala Gade, Lalitkumar K. Vora, Yu Wu, Alejandro J. Paredes, Ryan F. Donnelly & Thakur Raghu Raj Singh. (2023) Microneedles for advanced ocular drug delivery. Advanced Drug Delivery Reviews 201, pages 115082.
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Afroditi Kapourani, Katerina Kirimkiroglou, Konstantina Chachlioutaki, Maria Koromili, Christos Ritzoulis, Andreana N. Assimopoulou, Dimitrios A. Andreadis, Dimitrios G. Fatouros & Panagiotis Barmpalexis. (2023) Evaluation of pilocarpine in situ forming buccal gels as potential formulations for the management of xerostomia. Journal of Drug Delivery Science and Technology 86, pages 104698.
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Ta-Hsin Tsung, Yu-Chien Tsai, Hsin-Pei Lee, Yi-Hao Chen & Da-Wen Lu. (2023) Biodegradable Polymer-Based Drug-Delivery Systems for Ocular Diseases. International Journal of Molecular Sciences 24:16, pages 12976.
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Avin Sapowadia, Delaram Ghanbariamin, Libo Zhou, Qifa Zhou, Tannin Schmidt, Ali Tamayol & Yupeng Chen. (2023) Biomaterial Drug Delivery Systems for Prominent Ocular Diseases. Pharmaceutics 15:7, pages 1959.
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Rawan Fitaihi, Shorooq Abukhamees, Mine Orlu & Duncan Q. M. Craig. (2023) Transscleral Delivery of Dexamethasone-Loaded Microparticles Using a Dissolving Microneedle Array. Pharmaceutics 15:6, pages 1622.
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Ta-Hsin Tsung, Yi-Hao Chen & Da-Wen Lu. (2023) Updates on Biodegradable Formulations for Ocular Drug Delivery. Pharmaceutics 15:3, pages 734.
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Sujata Sawarkar, Prachi Pimple, Apurva Sawant & Sujit Nair. (2023) Current insights into targeting strategies for the effective therapy of diseases of the posterior eye segment. Critical Reviews in Therapeutic Drug Carrier Systems.
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Ziaul Karim, Preeti Karwa & Shobha Rani R. Hiremath. (2022) Polymeric microneedles for transdermal drug delivery- a review of recent studies. Journal of Drug Delivery Science and Technology 77, pages 103760.
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Piotr Gadziński, Anna Froelich, Monika Wojtyłko, Antoni Białek, Julia Krysztofiak & Tomasz Osmałek. (2022) Microneedle-based ocular drug delivery systems – recent advances and challenges. Beilstein Journal of Nanotechnology 13, pages 1167-1184.
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Qinying Yan, Shulin Shen, Yan Wang, Jiaqi Weng, Aiqun Wan, Gensheng Yang & Lili Feng. (2022) The Finite Element Analysis Research on Microneedle Design Strategy and Transdermal Drug Delivery System. Pharmaceutics 14:8, pages 1625.
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Heybet Kerem PolatNihat Kurt, Eren AytekinSibel Bozdağ PehlivanSema Çalış. (2022) Novel Drug Delivery Systems to Improve the Treatment of Keratitis. Journal of Ocular Pharmacology and Therapeutics.
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Pornsit Chaiya, Siriporn Okonogi & Thawatchai Phaechamud. (2022) Stereomicroscope with Imaging Analysis: A Versatile Tool for Wetting, Gel Formation and Erosion Rate Determinations of Eutectic Effervescent Tablet. Pharmaceutics 14:6, pages 1280.
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Yu Wu, Lalitkumar K. Vora, Deepakkumar Mishra, Muhammad Faris Adrianto, Shilpkala Gade, Alejandro J. Paredes, Ryan F. Donnelly & Thakur Raghu Raj Singh. (2022) Nanosuspension-loaded dissolving bilayer microneedles for hydrophobic drug delivery to the posterior segment of the eye. Biomaterials Advances 137, pages 212767.
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Jasmin Hassan, Charlotte Haigh, Tanvir Ahmed, Md Jasim Uddin & Diganta B. Das. (2022) Potential of Microneedle Systems for COVID-19 Vaccination: Current Trends and Challenges. Pharmaceutics 14:5, pages 1066.
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Pinal Chaudhari, Disha Shetty & Shaila A. Lewis. (2022) Recent progress in colloidal nanocarriers loaded in situ gel in ocular therapeutics. Journal of Drug Delivery Science and Technology 71, pages 103327.
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Lyndsey E. Moore, Sonja Vucen & Anne C. Moore. (2022) Trends in drug- and vaccine-based dissolvable microneedle materials and methods of fabrication. European Journal of Pharmaceutics and Biopharmaceutics 173, pages 54-72.
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Alyaa A. Albadr, Ismaiel A. Tekko, Lalitkumar K. Vora, Ahlam A. Ali, Garry Laverty, Ryan F. Donnelly & Raghu Raj Singh Thakur. (2021) Rapidly dissolving microneedle patch of amphotericin B for intracorneal fungal infections. Drug Delivery and Translational Research 12:4, pages 931-943.
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Girdhari Roy, Prashant Garg & Venkata Vamsi Krishna Venuganti. (2022) Microneedle scleral patch for minimally invasive delivery of triamcinolone to the posterior segment of eye. International Journal of Pharmaceutics 612, pages 121305.
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Maitri Bhatt & Pravin Shende. (2021) Modulated approaches for strategic transportation of proteins and peptides via ocular route. Journal of Drug Delivery Science and Technology 66, pages 102835.
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Bharti Gupta, Varsha Mishra, Sankalp Gharat, Munira Momin & Abdelwahab Omri. (2021) Cellulosic Polymers for Enhancing Drug Bioavailability in Ocular Drug Delivery Systems. Pharmaceuticals 14:11, pages 1201.
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Jie Xu, Danfeng Xu, Xuan Xuan & Huacheng He. (2021) Advances of Microneedles in Biomedical Applications. Molecules 26:19, pages 5912.
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Prateek Ranjan Yadav, Monika Nasrin Munni, Lauryn Campbell, Golam Mostofa, Lewis Dobson, Morayo Shittu, Sudip Kumar Pattanayek, Md. Jasim Uddin & Diganta Bhusan Das. (2021) Translation of Polymeric Microneedles for Treatment of Human Diseases: Recent Trends, Progress, and Challenges. Pharmaceutics 13:8, pages 1132.
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Pinal Chaudhari, Vivek M. Ghate & Shaila A. Lewis. (2021) Next-generation contact lenses: Towards bioresponsive drug delivery and smart technologies in ocular therapeutics. European Journal of Pharmaceutics and Biopharmaceutics 161, pages 80-99.
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Ognjenka Rahić, Amina Tucak, Naida Omerović, Merima Sirbubalo, Lamija Hindija, Jasmina Hadžiabdić & Edina Vranić. (2020) Novel Drug Delivery Systems Fighting Glaucoma: Formulation Obstacles and Solutions. Pharmaceutics 13:1, pages 28.
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