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Research Articles

Network pharmacology and molecular docking analysis on molecular targets and mechanisms of Huashi Baidu formula in the treatment of COVID-19

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Pages 1345-1353 | Received 04 May 2020, Accepted 04 Jun 2020, Published online: 08 Jul 2020

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Lili Lin, Li An, Hui Chen, Lu Feng, Mengjiang Lu, Yuling Liu, Chu Chu, Jinjun Shan, Tong Xie, Xiaorong Wang & Shouchuan Wang. (2021) Integrated Network Pharmacology and Lipidomics to Reveal the Inhibitory Effect of Qingfei Oral Liquid on Excessive Autophagy in RSV-Induced Lung Inflammation. Frontiers in Pharmacology 12.
Crossref
Rajeev K. Singla, Xuefei He, Hitesh Chopra, Christos Tsagkaris, Li Shen, Mohammad Amjad Kamal & Bairong Shen. (2021) Natural Products for the Prevention and Control of the COVID-19 Pandemic: Sustainable Bioresources. Frontiers in Pharmacology 12.
Crossref
Yi Wen Liu, Ai Xia Yang, Li Lu & Tie Hua Huang. (2021) Predicting the Molecular Mechanism of Sini Jia Renshen Decoction in Treating Severe COVID-19 Patients Based on Network Pharmacology and Molecular Docking. Natural Product Communications 16:12, pages 1934578X2110592.
Crossref
Ming Lyu, Guanwei Fan, Guangxu Xiao, Taiyi Wang, Dong Xu, Jie Gao, Shaoqin Ge, Qingling Li, Yuling Ma, Han Zhang, Jigang Wang, Yuanlu Cui, Junhua Zhang, Yan Zhu & Boli Zhang. (2021) Traditional Chinese medicine in COVID-19. Acta Pharmaceutica Sinica B 11:11, pages 3337-3363.
Crossref
Jiayi Yan, Panpan Ruan, Yunxuan Ge, Jing Gao, Hongling Tan, Chengrong Xiao, Quansheng Gao, Zhuo Zhang & Yue Gao. (2021) Mechanisms and Molecular Targets of Compound Danshen Dropping Pill for Heart Disease Caused by High Altitude Based on Network Pharmacology and Molecular Docking. ACS Omega 6:41, pages 26942-26951.
Crossref
Ying Zhang, Li Lu, YiWen Liu, AiXia Yang & Yanfang Yang. (2021) Predicting the Molecular Mechanism of Shenling Baizhu San in Treating Convalescent Patients With COVID-19 Based on Network Pharmacology and Molecular Docking. Natural Product Communications 16:10, pages 1934578X2110460.
Crossref
Jia Liu, Wei Yang, Yue Liu, Cheng Lu, Lianguo Ruan, Chen Zhao, Ruili Huo, Xin Shen, Qing Miao, Wenliang Lv, Hao Li, Huaxin Shi, Lijie Hu, Zhixu Yang, Li Zhang, Bing Wang, Guoju Dong, Yongyue Xian, Bin Li, Zhenqi Zhou, Chunyan Xu, Yingying Chen, Yongjun Bian, Jing Guo, Jinliang Yang, Jian Wang, Wensheng Qi, Suping Chen, Yang Chen, Bei Yan, Wei Wang, Jing Li, Xiaolei Xie, Ming Xu, Jianxin Jiang, Gang Wang, Xiaodong Cong, Haoning Zhu, Jiaheng Shi, Luxing Leng, Dongxu Li, Lanping Guo & Luqi Huang. (2021) Combination of Hua Shi Bai Du granule (Q-14) and standard care in the treatment of patients with coronavirus disease 2019 (COVID-19): A single-center, open-label, randomized controlled trial. Phytomedicine 91, pages 153671.
Crossref
Victor Moreira de Oliveira, Márcia Machado Marinho, Emanuel Paula Magalhães, Ramon Róseo Paula Pessoa Bezerra de Menezes, Tiago Lima Sampaio, Alice Maria Costa Martins, Hélcio Silva dos Santos & Emmanuel Silva Marinho. (2021) Molecular docking identification for the efficacy of natural limonoids against COVID-19 virus main protease. Journal of the Indian Chemical Society 98:10, pages 100157.
Crossref
Chen Zhao, Li Li, Wei Yang, Wenliang Lv, Jian Wang, Jing Guo, Yu Dong, Nannan Shi, Cheng Lu, Zhiqiang Li, Zhan Shi, Renbo Chen, Ruili Huo, Qianzi Che, Yaxin Tian, Xinghua Xiang, Jian Wang, Junhui Zhou, Yongjun Bian, Suping Chen, Yang Chen, Yingying Chen, Xiaodong Cong, Guoju Dong, Lijie Hu, Jianxin Jiang, Luxing Leng, Bin Li, Dongxu Li, Hao Li, Jing Li, Wensheng Qi, Qing Miao, Huaxin Shi, Jiaheng Shi, Bing Wang, Gang Wang, Wei Wang, Yongyue Xian, Xiaolei Xie, Chunyan Xu, Ming Xu, Bei Yan, Jinliang Yang, Li Zhang, Zhenqi Zhou, Haoning Zhu, Yibai Xiong, Bin Liu & Luqi Huang. (2021) Chinese Medicine Formula Huashibaidu Granule Early Treatment for Mild COVID-19 Patients: An Unblinded, Cluster-Randomized Clinical Trial. Frontiers in Medicine 8.
Crossref
Fei Wang, Jia-Hui Chen, Bo Liu & Ting Zhang. (2021) Analysis of the Active Components and Mechanism of Three Prescriptions in the Treatment of COVID-19 Via Network Pharmacology and Molecular Docking. Natural Product Communications 16:9, pages 1934578X2110477.
Crossref
Kai Huang, Pan Zhang, Zhenghao Zhang, Ji Youn Youn, Chen Wang, Hongchun Zhang & Hua Cai. (2021) Traditional Chinese Medicine (TCM) in the treatment of COVID-19 and other viral infections: Efficacies and mechanisms. Pharmacology & Therapeutics 225, pages 107843.
Crossref
Yunjia Hu, Meiqin Liu, Hongbo Qin, Haofeng Lin, Xiaoping An, Zhengli Shi, Lihua Song, Xinglou Yang, Huahao Fan & Yigang Tong. (2021) Artemether, Artesunate, Arteannuin B, Echinatin, Licochalcone B and Andrographolide Effectively Inhibit SARS-CoV-2 and Related Viruses In Vitro. Frontiers in Cellular and Infection Microbiology 11.
Crossref
Wenyang Wei, Wanpeng Lu, Xiaolong Chen, Yunfeng Yang & Mengkai Zheng. (2021) Use of Network Pharmacology to Investigate the Mechanism of the Compound Xuanju Capsule in the Treatment of Rheumatoid Arthritis. BioMed Research International 2021, pages 1-14.
Crossref
Liang Wang, Ying Ma, Yuqiong He, Jiuling Deng, Doudou Huang, Xiaoli Zhang, Kaixian Chen, Shi Qiu & Wansheng Chen. (2021) Systematic investigation of the pharmacological mechanism of Tanreqing injection in treating respiratory diseases by UHPLC/Q-TOF-MS/MS based on multiple in-house chemical libraries coupled with network pharmacology. Journal of Pharmaceutical and Biomedical Analysis 202, pages 114141.
Crossref
Evgenii Gusev, Alexey Sarapultsev, Desheng Hu & Valeriy Chereshnev. (2021) Problems of Pathogenesis and Pathogenetic Therapy of COVID-19 from the Perspective of the General Theory of Pathological Systems (General Pathological Processes). International Journal of Molecular Sciences 22:14, pages 7582.
Crossref
Yehong Tian, Xiaowei Qiu, Xin Jiang, Jin-Chang Huang & Fengyu Zhang. (2021) Application of Chinese Herbal Medicine in COVID-19. Global Clinical and Translational Research.
Crossref
Kai Niu, Qifang Li, Yuan Liu, Yi Qiao, Bingbing Li, Chao Wei, Kunrui Wang, Lu’an Cui, Canlei Zheng, Rong Wang, Li Zhang, Honghua Zhang, Bing Sun & Bin Yu. (2021) Molecular Targets and Mechanisms of Scutellariae radix-Coptidis rhizoma Drug Pair for the Treatment of Ulcerative Colitis Based on Network Pharmacology and Molecular Docking. Evidence-Based Complementary and Alternative Medicine 2021, pages 1-15.
Crossref
Hanting Xia, Jiangyuan Liu, Wenlong Yang, Min Liu, Yunfeng Luo, Zhijun Yang, Jingbo Xie, Huiliang Zeng, Rui Xu, Houfu Ling, Qinghe Zeng, Huihui Xu, Liang Fang, Hongyu Wang, Peijian Tong, Hongting Jin & Fengyun Yang. (2021) Integrated Strategy of Network Pharmacological Prediction and Experimental Validation Elucidate Possible Mechanism of Bu-Yang Herbs in Treating Postmenopausal Osteoporosis via ESR1. Frontiers in Pharmacology 12.
Crossref
Sheng-Teng Huang, Yeh Chen, Wei-Chao Chang, Hsiao-Fan Chen, Hsiang-Chun Lai, Yu-Chun Lin, Wei-Jan Wang, Yu-Chuan Wang, Chia-Shin Yang, Shao-Chun Wang & Mien-Chie Hung. (2021) Scutellaria barbata D. Don Inhibits the Main Proteases (Mpro and TMPRSS2) of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection. Viruses 13:5, pages 826.
Crossref
Ling Li, Xiao‐jie Jin, Jia‐wei Li, Cheng‐hao Li, Shuang‐yan Zhou, Jun‐jie Li, Cai‐qin Feng, Dong‐ling Liu & Yong‐qi Liu. (2021) Systematic insight into the active constituents and mechanism of Guiqi Baizhu for the treatment of gastric cancer. Cancer Science 112:5, pages 1772-1784.
Crossref
Wei Ren, Pan Liang, Yue Ma, Qin Sun, Qingrong Pu, Li Dong, Gang Luo, Maryam Mazhar, Jiali Liu, Raoqiong Wang & Sijin Yang. (2021) Research progress of traditional Chinese medicine against COVID-19. Biomedicine & Pharmacotherapy 137, pages 111310.
Crossref
Jianxiong Wu, Xietao Ye, Songhong Yang, Huan Yu, Lingyun Zhong & Qianfeng Gong. (2021) Systems Pharmacology Study of the Anti-Liver Injury Mechanism of Citri Reticulatae Pericarpium. Frontiers in Pharmacology 12.
Crossref
Jieya Wu, Baoguo Sun, Li Hou, Fulan Guan, Liyuan Wang, Peikwen Cheng, Sophia Scobell, Yung-Chi Cheng & Wing Lam. (2021) Prospective: Evolution of Chinese Medicine to Treat COVID-19 Patients in China. Frontiers in Pharmacology 11.
Crossref
Yuehua Wang, Wenwen Gu, Fuguang Kui, Fan Gao, Yuji Niu, Wenwen Li, Yaru Zhang, Zhenzhen Guo & Gangjun Du. (2021) The mechanism and active compounds of semen armeniacae amarum treating coronavirus disease 2019 based on network pharmacology and molecular docking. Food & Nutrition Research 65.
Crossref
Xue Bai, Yibo Tang, Qiang Li, Yafei Chen, Dan Liu, Guimin Liu, Xiaolei Fan, Ru Ma, Shuyan Wang, Lingru Li, Kailin Zhou, Yanfei Zheng & Zhenquan Liu. (2021) Network pharmacology integrated molecular docking reveals the bioactive components and potential targets of Morinda officinalis–Lycium barbarum coupled-herbs against oligoasthenozoospermia. Scientific Reports 11:1.
Crossref
Yue-Yu Gu, Min Zhang, Huan Cen, Yi-Fan Wu, Zhaoyu Lu, Fuhua Lu, Xu-Sheng Liu & Hui-Yao Lan. (2021) Quercetin as a potential treatment for COVID-19-induced acute kidney injury: Based on network pharmacology and molecular docking study. PLOS ONE 16:1, pages e0245209.
Crossref
Jialin Li, Zhihong Huang, Shan Lu, Hua Luo, Yingying Tan, Peizhi Ye, Xinkui Liu, Zhishan Wu, Chao Wu, Antony Stalin, Haojia Wang, Yingying Liu, Liangliang Shen, Xiaotian Fan, Bei Zhang, Jianping Yi, Lu Yao, Yi Xu, Jiarui Wu & Xianchun Duan. (2021) Exploring potential mechanisms of Suhexiang Pill against COVID-19 based on network pharmacology and molecular docking. Medicine 100:51, pages e27112.
Crossref
Xinyao Ouyang. Molecular mechanism of catalpol in the treatment of diabetes mellitus based on network pharmacology and molecular docking. Molecular mechanism of catalpol in the treatment of diabetes mellitus based on network pharmacology and molecular docking.
Linyu Bo, Yulin Zhang, Xiumei Wu, Ancui Ma, Yu Zhao, Heng Liu, Miao He & Chenggui Zhang. (2021) Effect and mechanism of Kangfuxin liquid on oral ulcer in patients with chemotherapy treated hematologic malignancies: Network pharmacology study and clinical observations. Informatics in Medicine Unlocked 25, pages 100693.
Crossref
Jin-gen Li & Hao Xu. (2021) Chinese Medicine in Fighting against Covid-19: Role and Inspiration. Chinese Journal of Integrative Medicine 27:1, pages 3-6.
Crossref
Saqib Mahmood, Tariq Mahmood, Naeem Iqbal, Samina Sabir, Sadia Javed & Muhammad Zia-Ul-Haq. 2021. Alternative Medicine Interventions for COVID-19. Alternative Medicine Interventions for COVID-19 63 109 .
Lizhu Han, Yunlan Wang, Kunxia Hu, Zhishu Tang & Xiao Song. (2020) The therapeutic efficacy of Huashi Baidu Formula combined with antiviral drugs in the treatment of COVID-19. Medicine 99:42, pages e22715.
Crossref

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