572
Views
60
CrossRef citations to date
0
Altmetric
Original Research

Medium Chain Triglyceride Oil Consumption as Part of a Weight Loss Diet Does Not Lead to an Adverse Metabolic Profile When Compared to Olive Oil

, PhD, , BA, , RD, MSc & , RD
Pages 547-552 | Received 10 Dec 2007, Accepted 21 Mar 2008, Published online: 13 Jun 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Rituparna Maiti, Rashmi Ranjan Mohanty, Anupam Dey, Shampa Maji, Milan Padhan & Archana Mishra. (2023) Effect of Virgin Coconut Oil (VCO) on Cardiometabolic Parameters in Patients with Dyslipidemia: A Randomized, Add-on Placebo-Controlled Clinical Trial. Journal of the American Nutrition Association 0:0, pages 1-8.
Read now
Yee-Ying Lee, Teck-Kim Tang, Eng-Seng Chan, Eng-Tong Phuah, Oi-Ming Lai, Chin-Ping Tan, Yong Wang, Nur Azwani Ab Karim, Noorlida Habi Mat Dian & Joo Shun Tan. (2022) Medium chain triglyceride and medium-and long chain triglyceride: metabolism, production, health impacts and its applications – a review. Critical Reviews in Food Science and Nutrition 62:15, pages 4169-4185.
Read now
Tohru Ohnuma, Aiko Toda, Ayako Kimoto, Yuto Takebayashi, Ryoko Higashiyama, Yuko Tagata, Masanobu Ito, Tsuneyoshi Ota, Nobuto Shibata & Heii Arai. (2016) Benefits of use, and tolerance of, medium-chain triglyceride medical food in the management of Japanese patients with Alzheimer’s disease: a prospective, open-label pilot study. Clinical Interventions in Aging 11, pages 29-36.
Read now
Miriam E. Clegg. (2010) Medium-chain triglycerides are advantageous in promoting weight loss although not beneficial to exercise performance. International Journal of Food Sciences and Nutrition 61:7, pages 653-679.
Read now

Articles from other publishers (56)

Jinshan Zhao, Fan Zhao, Junmeng Yuan, Huawei Liu & Yang Wang. (2023) Gut microbiota metabolites, redox status, and the related regulatory effects of probiotics. Heliyon 9:11, pages e21431.
Crossref
Askale Gebremichael, András Szabó, Zsuzsanna J. Sándor, Zoltán Nagy, Omeralfaroug Ali & Balázs Kucska. (2023) Chemical and Physical Properties of African Catfish (Clarias gariepinus) Fillet Following Prolonged Feeding with Insect Meal-Based Diets. Aquaculture Nutrition 2023, pages 1-9.
Crossref
Rudy Agung Nugroho, Retno Aryani, Esti Handayani Hardi, Hetty Manurung, Rudianto Rudianto, Nadhifa Aurellia Wirawan, Nadya Syalsabillah & Wibowo Nugroho Jati. (2023) Nutritive value, material reduction, biomass conversion rate, and survival of black solider fly larvae reared on palm kernel meal supplemented with fish pellets and fructose. International Journal of Tropical Insect Science 43:4, pages 1243-1254.
Crossref
Gabriela de Oliveira Lemos, Raquel Susana Torrinhas & Dan Linetzky Waitzberg. (2023) Nutrients, Physical Activity, and Mitochondrial Dysfunction in the Setting of Metabolic Syndrome. Nutrients 15:5, pages 1217.
Crossref
Pengbo Wang, Dongman Wan, Ting Peng, Yujing Yang, Xuefang Wen, Xianghui Yan, Jiaheng Xia, Qingwen Zhu, Ping Yu, Deming Gong & Zheling Zeng. (2023) Acute Oral Toxicity and Genotoxicity Test and Evaluation of Cinnamomum camphora Seed Kernel Oil. Foods 12:2, pages 293.
Crossref
Mohammad H. Alyami, Hamad S. Alyami, Abdullah A. Alshehri, Wijdan K. Alsharif, Ibrahim Ahmed Shaikh & Thamer S. Algahtani. (2022) Tamoxifen Citrate Containing Topical Nanoemulgel Prepared by Ultrasonication Technique: Formulation Design and In Vitro Evaluation. Gels 8:7, pages 456.
Crossref
Danping Wang, Jinglong Chen, Huangbing Sun, Wenjing Chen & Xiaojing Yang. (2022) MCFA alleviate H 2 O 2 ‐induced oxidative stress in AML12 cells via the ERK1 /2/Nrf2 pathway . Lipids 57:3, pages 153-162.
Crossref
Nicholas Romano, Hayden Fischer, Vikas Kumar, Shaun A. Francis & Amit Kumar Sinha. (2021) Productivity, conversion ability, and biochemical composition of black soldier fly (Hermetia illucens) larvae fed with sweet potato, spent coffee or dough. International Journal of Tropical Insect Science 42:1, pages 183-190.
Crossref
Hayden Fischer, Nicholas Romano, Nilima Renukdas, Vikas Kumar & Amit Kumar Sinha. (2022) Comparing black soldier fly (Hermetia illucens) larvae versus prepupae in the diets of largemouth bass, Micropterus salmoides: Effects on their growth, biochemical composition, histopathology, and gene expression. Aquaculture 546, pages 737323.
Crossref
Md. Sakhawat Hossain, Mo Peng & Brian C. Small. (2021) Optimizing the fatty acid profile of novel terrestrial oil blends in low fishmeal diets of rainbow trout (Oncorhynchus mykiss) yields comparable fish growth, total fillet n-3 LC-PUFA content, and health performance relative to fish oil. Aquaculture 545, pages 737230.
Crossref
Nathan Egnew, Nicholas Romano, Hayden Fischer & Amit Kumar Sinha. (2021) Purging black solider fly larvae (Hermetia illucens) compromises their nutritive value as a feedstuff. International Journal of Tropical Insect Science 41:4, pages 3279-3286.
Crossref
Ivoneide M. Menezes Barra, André Silva dos Reis, Helder Kiyoshi Miyagawa, Strahil Berkov & Alberdan Silva Santos. (2021) Systematic investigation and lipidomic profiles composition characterization in leaves of five Amaryllidaceae species by HRGC-MS technique. South African Journal of Botany 142, pages 25-33.
Crossref
Kirsty M McKenzie, Crystal My Lee, Jovana Mijatovic, Marjan Mosalman Haghighi & Michael R Skilton. (2021) Medium-Chain Triglyceride Oil and Blood Lipids: A Systematic Review and Meta-Analysis of Randomized Trials. The Journal of Nutrition 151:10, pages 2949-2956.
Crossref
Lili Huang, Lin Gao & Chen Chen. (2021) Role of Medium-Chain Fatty Acids in Healthy Metabolism: A Clinical Perspective. Trends in Endocrinology & Metabolism 32:6, pages 351-366.
Crossref
Hayden Fischer, Nicholas Romano & Amit Kumar Sinha. (2021) Conversion of Spent Coffee and Donuts by Black Soldier Fly (Hermetia illucens) Larvae into Potential Resources for Animal and Plant Farming. Insects 12:4, pages 332.
Crossref
Adeola T. Salami, Chioma E. Okonkwo, Francis A. Attah & Olawande C. Olagoke. (2021) Bioactive Moringa olifera seed extracts attenuates cholesterol gall stones in hyperglycaemic Swiss mice. Comparative Clinical Pathology 30:2, pages 207-216.
Crossref
Janine Mett & Uli Müller. (2021) The medium-chain fatty acid decanoic acid reduces oxidative stress levels in neuroblastoma cells. Scientific Reports 11:1.
Crossref
Vikas Kumar, Femi J. Fawole, Nicholas Romano, Md Sakhawat Hossain, Shyam N. Labh, Ken Overturf & Brian C. Small. (2021) Insect (black soldier fly, Hermetia illucens) meal supplementation prevents the soybean meal-induced intestinal enteritis in rainbow trout and health benefits of using insect oil. Fish & Shellfish Immunology 109, pages 116-124.
Crossref
Gerwyn Morris, Basant K Puri, Andre Carvalho, Michael Maes, Michael Berk, Anu Ruusunen & Lisa Olive. (2020) Induced Ketosis as a Treatment for Neuroprogressive Disorders: Food for Thought?. International Journal of Neuropsychopharmacology 23:6, pages 366-384.
Crossref
Siyu Wang, Yu Wang, Fereidoon Shahidi & Chi‐Tang Ho. 2005. Bailey's Industrial Oil and Fat Products. Bailey's Industrial Oil and Fat Products 1 22 .
Stella Lucia Volpe. (2020) Medium-Chain Triglycerides and Health. ACSM'S Health & Fitness Journal 24:1, pages 35-36.
Crossref
E. Guillocheau, M. Milard, V. Rioux, C. Bourlieu & M.-C. Michalski. 2020. Advanced Dairy Chemistry, Volume 2. Advanced Dairy Chemistry, Volume 2 307 344 .
Vishwanath M. Sardesai. 2020. Integrative and Functional Medical Nutrition Therapy. Integrative and Functional Medical Nutrition Therapy 135 149 .
Dylan D. Thomas, Mary-Catherine Stockman, Liqun Yu, Tova Meshulam, Ashley C. McCarthy, Annaliese Ionson, Nathan Burritt, Jude Deeney, Howard Cabral, Barbara Corkey, Nawfal Istfan & Caroline M. Apovian. (2019) Effects of medium chain triglycerides supplementation on insulin sensitivity and beta cell function: A feasibility study. PLOS ONE 14:12, pages e0226200.
Crossref
Xinsheng Zhang, Changyong Xue, Qing Xu, Yong Zhang, Huizi Li, Feng Li, Yinghua Liu & Changjiang Guo. (2019) Caprylic acid suppresses inflammation via TLR4/NF-κB signaling and improves atherosclerosis in ApoE-deficient mice. Nutrition & Metabolism 16:1.
Crossref
Ikram Belghit, Rune Waagbø, Erik-Jan Lock & Nina S. Liland. (2019) Insect-based diets high in lauric acid reduce liver lipids in freshwater Atlantic salmon. Aquaculture Nutrition 25:2, pages 343-357.
Crossref
Noemí Redondo, Natalia García-González, Ligia E. Diaz-Prieto, Begoña Olmedilla-Alonso, Ana B. Martín-Diana, Carmen Asensio-Vegas & Esther Nova. (2018) Effects of ewe’s milk yogurt (whole and semi-skimmed) and cow’s milk yogurt on inflammation markers and gut microbiota of subjects with borderline-high plasma cholesterol levels: a crossover study. European Journal of Nutrition 58:3, pages 1113-1124.
Crossref
Ikram Belghit, Nina S. Liland, Petter Gjesdal, Irene Biancarosa, Elisa Menchetti, Yanxian Li, Rune Waagbø, Åshild Krogdahl & Erik-Jan Lock. (2019) Black soldier fly larvae meal can replace fish meal in diets of sea-water phase Atlantic salmon (Salmo salar). Aquaculture 503, pages 609-619.
Crossref
Yoshihiro Miyagawa, Takuya Mori, Kei Goto, Isao Kawahara, Rina Fujiwara-Tani, Shingo Kishi, Takamitsu Sasaki, Kiyomu Fujii, Hitoshi Ohmori & Hiroki Kuniyasu. (2018) Intake of medium-chain fatty acids induces myocardial oxidative stress and atrophy. Lipids in Health and Disease 17:1.
Crossref
Nicholas Buss, Patricia Ryan, Todd Baughman, Denis Roy, Claire Patterson, Carolyn Gordon & Rakesh Dixit. (2018) Nonclinical safety and pharmacokinetics of Miglyol 812: A medium chain triglyceride in exenatide once weekly suspension. Journal of Applied Toxicology 38:10, pages 1293-1301.
Crossref
Adriana Lelis Carvalho, Victoria E. DeMambro, Anyonya R. Guntur, Phuong Le, Kenichi Nagano, Roland Baron, Francisco José Albuquerque de Paula & Katherine J. Motyl. (2017) High fat diet attenuates hyperglycemia, body composition changes, and bone loss in male streptozotocin‐induced type 1 diabetic mice. Journal of Cellular Physiology 233:2, pages 1585-1600.
Crossref
Devi Lekshmi Sheela, Puthiyaveetil Abdulla Nazeem, Arunaksharan Narayanankutty, R. Muthangaparambil Shylaja, Sangeetha P. Davis, Priyanga James, Ravisankar Valsalan, Thekkekara Devassy Babu & Achuthan C. Raghavamenon. (2017) Coconut phytocompounds inhibits polyol pathway enzymes: Implication in prevention of microvascular diabetic complications. Prostaglandins, Leukotrienes and Essential Fatty Acids 127, pages 20-24.
Crossref
Rojeet Shrestha, Ken-ichi Hirano, Akira Suzuki, Satoshi Yamaguchi, Yusuke Miura, Yi-Fan Chen, Masahiro Mizuta, Hitoshi Chiba & Shu-Ping Hui. (2017) Change in Plasma Total, Esterified and Non-esterified Capric Acid Concentrations during a Short-term Oral Administration of Synthetic Tricaprin in Dogs. Analytical Sciences 33:11, pages 1297-1303.
Crossref
Bert van de Heijning, Annemarie Oosting, Diane Kegler & Eline van der Beek. (2017) An Increased Dietary Supply of Medium-Chain Fatty Acids during Early Weaning in Rodents Prevents Excessive Fat Accumulation in Adulthood. Nutrients 9:6, pages 631.
Crossref
Maitreyi Raman, Abdulelah Almutairdi, Leanne Mulesa, Cathy Alberda, Colleen Beattie & Leah Gramlich. (2017) Parenteral Nutrition and Lipids. Nutrients 9:4, pages 388.
Crossref
Ismael Saifudeen, Lakshmi Subhadra, Remani Konnottil & R. Renuka Nair. (2017) Metabolic Modulation by Medium-Chain Triglycerides Reduces Oxidative Stress and Ameliorates CD36-Mediated Cardiac Remodeling in Spontaneously Hypertensive Rat in the Initial and Established Stages of Hypertrophy. Journal of Cardiac Failure 23:3, pages 240-251.
Crossref
Xinsheng Zhang, Yong Zhang, Yinghua Liu, Jin Wang, Qing Xu, Xiaoming Yu, Xueyan Yang, Zhao Liu & Changyong Xue. (2016) Medium-chain triglycerides promote macrophage reverse cholesterol transport and improve atherosclerosis in ApoE-deficient mice fed a high-fat diet. Nutrition Research 36:9, pages 964-973.
Crossref
Sabri Rial, Antony Karelis, Karl-F. Bergeron & Catherine Mounier. (2016) Gut Microbiota and Metabolic Health: The Potential Beneficial Effects of a Medium Chain Triglyceride Diet in Obese Individuals. Nutrients 8:5, pages 281.
Crossref
Shanshan Geng, Weiwei Zhu, Chunfeng Xie, Xiaoting Li, Jieshu Wu, Zhaofeng Liang, Wei Xie, Jianyun Zhu, Cong Huang, Mingming Zhu, Rui Wu & Caiyun Zhong. (2015) Medium-chain triglyceride ameliorates insulin resistance and inflammation in high fat diet-induced obese mice. European Journal of Nutrition 55:3, pages 931-940.
Crossref
Nilam Bhavsar & Marie-Pierre St-Onge. (2016) The diverse nature of saturated fats and the case of medium-chain triglycerides. Current Opinion in Clinical Nutrition and Metabolic Care 19:2, pages 81-87.
Crossref
Fanny Lemarié, Erwan Beauchamp, Philippe Legrand & Vincent Rioux. (2016) Revisiting the metabolism and physiological functions of caprylic acid (C8:0) with special focus on ghrelin octanoylation. Biochimie 120, pages 40-48.
Crossref
L. Brown, H. Poudyal & S. K. Panchal. (2015) Functional foods as potential therapeutic options for metabolic syndrome. Obesity Reviews 16:11, pages 914-941.
Crossref
Fanny Lemarié, Erwan Beauchamp, Stéphanie Dayot, Cécile Duby, Philippe Legrand & Vincent Rioux. (2015) Dietary Caprylic Acid (C8:0) Does Not Increase Plasma Acylated Ghrelin but Decreases Plasma Unacylated Ghrelin in the Rat. PLOS ONE 10:7, pages e0133600.
Crossref
Hemant Poudyal & Lindsay Brown. (2015) Should the pharmacological actions of dietary fatty acids in cardiometabolic disorders be classified based on biological or chemical function?. Progress in Lipid Research 59, pages 172-200.
Crossref
Benoît Lamarche & Patrick Couture. (2015) Dietary fatty acids, dietary patterns, and lipoprotein metabolism. Current Opinion in Lipidology 26:1, pages 42-47.
Crossref
Karen Mumme & Welma Stonehouse. (2015) Effects of Medium-Chain Triglycerides on Weight Loss and Body Composition: A Meta-Analysis of Randomized Controlled Trials. Journal of the Academy of Nutrition and Dietetics 115:2, pages 249-263.
Crossref
Alok Sharma, Marc Bemis & Alicia R. Desilets. (2014) Role of Medium Chain Triglycerides (Axona ® ) in the Treatment of Mild to Moderate Alzheimer’s Disease . American Journal of Alzheimer's Disease & Other Dementiasr 29:5, pages 409-414.
Crossref
André J Tremblay, Benoît Lamarche, Marie-Ève Labonté, Marie-Claude Lépine, Valéry Lemelin & Patrick Couture. (2014) Dietary medium-chain triglyceride supplementation has no effect on apolipoprotein B-48 and apolipoprotein B-100 kinetics in insulin-resistant men. The American Journal of Clinical Nutrition 99:1, pages 54-61.
Crossref
Jun Ding, Ursula Loizides-Mangold, Gianpaolo Rando, Vincent Zoete, Olivier Michielin, Janardan K. Reddy, Walter Wahli, Howard Riezman & Bernard Thorens. (2013) The Peroxisomal Enzyme L-PBE Is Required to Prevent the Dietary Toxicity of Medium-Chain Fatty Acids. Cell Reports 5:1, pages 248-258.
Crossref
Michael V Dodson, Sihem Boudina, Elke Albrecht, Luke Bucci, Melinda Fernyhough Culver, Shengjuan Wei, Werner G Bergen, Andreia J Amaral, Naima Moustaid-Moussa, Sylvia Poulos & Gary J Hausman. (2013) A long journey to effective obesity treatments: is there light at the end of the tunnel?. Experimental Biology and Medicine 238:5, pages 491-501.
Crossref
A. Cláudia Figueiredo-Silva, Sadasivam Kaushik, Frédéric Terrier, Johan W. Schrama, Françoise Médale & Inge Geurden. (2011) Link between lipid metabolism and voluntary food intake in rainbow trout fed coconut oil rich in medium-chain TAG. British Journal of Nutrition 107:11, pages 1714-1725.
Crossref
Raghu R.V. Malapaka, SokKean Khoo, Jifeng Zhang, Jang H. Choi, X. Edward Zhou, Yong Xu, Yinhan Gong, Jun Li, Eu-Leong Yong, Michael J. Chalmers, Lin Chang, James H. Resau, Patrick R. Griffin, Y. Eugene Chen & H. Eric Xu. (2012) Identification and Mechanism of 10-Carbon Fatty Acid as Modulating Ligand of Peroxisome Proliferator-activated Receptors. Journal of Biological Chemistry 287:1, pages 183-195.
Crossref
A. G. Dulloo. (2011) The search for compounds that stimulate thermogenesis in obesity management: from pharmaceuticals to functional food ingredients. Obesity Reviews 12:10, pages 866-883.
Crossref
J.I. Pedersen & B. Kirkhus. 2011. Reducing Saturated Fats in Foods. Reducing Saturated Fats in Foods 77 97 .
Peter J. Huth, Victor Fulgoni, Ronald J. Jandacek, Peter J. Jones, Marie-Pierre St-Onge & Vijitha Senanayake. (2010) Bioactivity and emerging role of short and medium chain fatty acids. Lipid Technology 22:12, pages 266-269.
Crossref
David J. A. Jenkins, Arash Mirrahimi, Tri H. Nguyen, Shahad Abdulnour, Korbua Srichaikul, Leanne Shamrakov, Ambika Dewan, John L. Sievenpiper & Cyril W. C. Kendall. (2010) Macronutrients, Weight Control, and Cardiovascular Health: A Systematic Review. Current Cardiovascular Risk Reports 4:2, pages 89-100.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.