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Journal of Carbohydrate Chemistry Volume 30, 2011 - Issue 4-6: The 5th Glycan Forum in Berlin
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Original Articles

Toward Efficient Enzymatic Glycan Synthesis: Directed Evolution and Enzyme Engineering

David H. Kwan Centre for High-Throughput Biology, University of British Columbia, 2125 East Mall, Vancouver, B.C., Canada, V6T 1Z4
&
Stephen G. Withers Centre for High-Throughput Biology, University of British Columbia, 2125 East Mall, Vancouver, B.C., Canada, V6T 1Z4
Pages 181-205 | Received 24 May 2011, Accepted 07 Jul 2011, Published online: 09 Nov 2011

Citations (14)

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Koen Beerens, Stevie Van Overtveldt & Tom Desmet. (2017) The “epimerring” highlights the potential of carbohydrate epimerases for rare sugar production. Biocatalysis and Biotransformation 35:3, pages 230-237.
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Articles from other publishers (13)

Sara Ouadhi, Dulce María Valdez López, F Ifthiha Mohideen & David H Kwan. (2023) Engineering the enzyme toolbox to tailor glycosylation in small molecule natural products and protein biologics. Protein Engineering, Design and Selection 36.
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F. Ifthiha Mohideen, Trisha Ghosh, Lan Huong Nguyen & David H. Kwan. 2021. Comprehensive Glycoscience. Comprehensive Glycoscience 204 232 .
Lemeng Chao & Seino Jongkees. (2019) High‐Throughput Approaches in Carbohydrate‐Active Enzymology: Glycosidase and Glycosyl Transferase Inhibitors, Evolution, and Discovery. Angewandte Chemie International Edition 58:37, pages 12750-12760.
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Lemeng Chao & Seino Jongkees. (2019) High‐Throughput Approaches in Carbohydrate‐Active Enzymology: Glycosidase and Glycosyl Transferase Inhibitors, Evolution, and Discovery. Angewandte Chemie 131:37, pages 12880-12890.
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Kieran L. HudsonKieran L. Hudson. 2018. Carbohydrate-Based Interactions at the Molecular and the Cellular Level. Carbohydrate-Based Interactions at the Molecular and the Cellular Level 1 34 .
David H. Kwan. 2017. Chemical Glycobiology Part A. Synthesis, Manipulation and Applications of Glycans. Chemical Glycobiology Part A. Synthesis, Manipulation and Applications of Glycans 25 53 .
Aníbal Cuetos, Marina García-Ramos, Eva-Maria Fischereder, Alba Díaz-Rodríguez, Gideon Grogan, Vicente Gotor, Wolfgang Kroutil & Iván Lavandera. (2016) Catalytic Promiscuity of Transaminases: Preparation of Enantioenriched β-Fluoroamines by Formal Tandem Hydrodefluorination/Deamination. Angewandte Chemie International Edition 55:9, pages 3144-3147.
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Aníbal Cuetos, Marina García-Ramos, Eva-Maria Fischereder, Alba Díaz-Rodríguez, Gideon Grogan, Vicente Gotor, Wolfgang Kroutil & Iván Lavandera. (2016) Catalytic Promiscuity of Transaminases: Preparation of Enantioenriched β-Fluoroamines by Formal Tandem Hydrodefluorination/Deamination. Angewandte Chemie 128:9, pages 3196-3199.
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Stevie Van Overtveldt, Tom Verhaeghe, Henk-Jan Joosten, Tom van den Bergh, Koen Beerens & Tom Desmet. (2015) A structural classification of carbohydrate epimerases: From mechanistic insights to practical applications. Biotechnology Advances 33:8, pages 1814-1828.
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Zachary Armstrong & Stephen G. Withers. (2013) Synthesis of Glycans and Glycopolymers Through Engineered Enzymes. Biopolymers 99:10, pages 666-674.
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Koen Beerens, Wim Soetaert & Tom Desmet. (2012) Characterization and mutational analysis of the UDP-Glc(NAc) 4-epimerase from Marinithermus hydrothermalis. Applied Microbiology and Biotechnology 97:17, pages 7733-7740.
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Jinhua Wei, Xun Lv, Yang Lü, Gangzhu Yang, Lifeng Fu, Liu Yang, Jianjun Wang, Jianhui Gao, Shuihong Cheng, Qian Duan, Cheng Jin & Xuebing Li. (2013) Glycosynthase with Broad Substrate Specificity - an Efficient Biocatalyst for the Construction of Oligosaccharide Library. European Journal of Organic Chemistry 2013:12, pages 2414-2419.
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David H. Kwan & Stephen G. Withers. (2012) ChemInform Abstract: Toward Efficient Enzymatic Glycan Synthesis: Directed Evolution and Enzyme Engineering. ChemInform 43:12.
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