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Nucleosides and Nucleotides Volume 15, 1996 - Issue 5
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Original Articles

A Rapid, High-Yield Method for 5′-Hydroxyl Protection in Very Reactive and Amino Group Modified Nucleosides Using Dimethoxytrityl Tetrafluoroborate

Mahesh K. Lakshman Chemsyn Science Laboratories, 13605 West 96th Terrace, Lenexa, KS, 66215
&
Barbara Zajc Department of Chemistry, University of Ljubljana, Aškerceva 5, 61000, Ljubljana, Slovenia
Pages 1029-1039 | Received 02 Oct 1995, Accepted 05 Jan 1996, Published online: 15 Aug 2006

Citations (12)

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MarkP. Wallis, CarlH. Schwalbe & William Fraser. (1997) Synthesis and Stability of Oligonucleotide Duplexes Containing N4 Aralkyl-Substituted Cytosine Bases. Nucleosides and Nucleotides 16:10-11, pages 2053-2068.
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Articles from other publishers (11)

Yeong Jun Yu, Heejung Kim, Chan-Moon Chung & Jae Woo Chung. (2022) Damage-Detectable and Self-Healable Photoluminescent Dual Dynamic Supramolecular Networks. ACS Applied Polymer Materials 4:12, pages 9103-9115.
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Ioannis A. Trantakis, Arman Nilforoushan, Heidi A. Dahlmann, Celine K. Stäuble & Shana J. Sturla. (2016) In-Gene Quantification of O 6 -Methylguanine with Elongated Nucleoside Analogues on Gold Nanoprobes . Journal of the American Chemical Society 138:27, pages 8497-8504.
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Hari Prasad Kokatla & Mahesh K. Lakshman. (2012) Two‐Step, One‐Pot Synthesis of Inosine, Guanosine, and 2′‐Deoxyguanosine O 6 ‐Ethers via Intermediate O 6 ‐(Benzotriazol‐1‐yl) Derivatives . Current Protocols in Nucleic Acid Chemistry 49:1.
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Anders S. Hansen, Armin Thalhammer, Afaf H. El-Sagheer, Tom Brown & Christopher J. Schofield. (2011) Improved synthesis of 5-hydroxymethyl-2′-deoxycytidine phosphoramidite using a 2′-deoxyuridine to 2′-deoxycytidine conversion without temporary protecting groups. Bioorganic & Medicinal Chemistry Letters 21:4, pages 1181-1184.
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Suyeal Bae, Surendra Chaturvedi & Mahesh K. Lakshman. (2009) O 6 ‐(Benzotriazol‐1‐yl)inosine Derivatives for C6 Modification of Purine Nucleosides . Current Protocols in Nucleic Acid Chemistry 36:1.
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Suyeal Bae & Mahesh K. Lakshman. (2008) A Novel Polymer Supported Approach to Nucleoside Modification. The Journal of Organic Chemistry 73:10, pages 3707-3713.
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Haruhiko Yagi, Andagar R. Ramesha, Govind Kalena, Jane M. Sayer, Subodh Kumar & Donald M. Jerina. (2002) Novel Stereoselective Control over Cis vs Trans Opening of Benzo[ c ]phenanthrene 3,4-Diol 1,2-Epoxides by the Exocyclic N 2 -Amino Group of Deoxyguanosine in the Presence of Hexafluoropropan-2-ol . The Journal of Organic Chemistry 67:19, pages 6678-6689.
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Paula Francom, Zlatko Janeba, Susumu Shibuya & Morris J. Robins. (2002) Nucleic Acid Related Compounds. 116. Nonaqueous Diazotization of Aminopurine Nucleosides. Mechanistic Considerations and Efficient Procedures with tert- Butyl Nitrite or Sodium Nitrite , 1 . The Journal of Organic Chemistry 67:19, pages 6788-6796.
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Tsutomu Tsuchiya. 2001. Glycoscience: Chemistry and Chemical Biology I–III. Glycoscience: Chemistry and Chemical Biology I–III 117 194 .
H. Seliger. (2001) Protection of 5′‐Hydroxy Functions of Nucleosides. Current Protocols in Nucleic Acid Chemistry 00:1.
Crossref
M. K. LAKSHMAN & B. ZAJC. (2010) ChemInform Abstract: A Rapid, High‐Yield Method for 5′‐Hydroxyl Protection in Very Reactive and Amino Group Modified Nucleosides Using Dimethoxytrityl Tetrafluoroborate.. ChemInform 27:36.
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