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I. PROGRESS IN SECOND GENERATION OLIGOMER THERAPEUTICS

2′-O-Methyl Thiomethyl Modifications in Hammerhead Ribozymes

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Pages 955-958 | Published online: 16 Aug 2006

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Martin Dunkel & Vivian Reither. (2000) Replacement of the Phosphodiester Bond Between U4 and G5 in the U-Turn of a Chemically Modified Hammerhead Ribozyme by an Amide Bond. Nucleosides, Nucleotides & Nucleic Acids 19:4, pages 749-756.
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Balla Sylla, Charles Gauthier, Jean Legault, Pierre-Yves Fleury, Serge Lavoie, Vakhtang Mshvildadze, Tamar Muzashvili, Eter Kemertelidze & André Pichette. (2014) Isolation of a new disaccharide nucleoside from Helleborus caucasicus: structure elucidation and total synthesis of hellecaucaside A and its β-anomer. Carbohydrate Research 398, pages 80-89.
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Yosuke Ochi, Osamu Nakagawa, Katsunori Sakaguchi, Shun-ichi Wada & Hidehito Urata. (2013) A post-synthetic approach for the synthesis of 2′-O-methyldithiomethyl-modified oligonucleotides responsive to a reducing environment. Chemical Communications 49:69, pages 7620.
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Christoph Hermann, Evgeny Kvassiouk & Wolfgang Pfleiderer. (2011) Nucleotides. Part LXXIX. Helvetica Chimica Acta 94:3, pages 362-370.
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Timofei S Zatsepin, Elena A Romanova & Tat'yana S Oretskaya. (2002) Synthesis of 2'- O -alkylnucleosides . Russian Chemical Reviews 71:6, pages 513-534.
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A. E. Pechenov, S. G. Zavgorodny, V. I. Shvets & A. I. Miroshnikov. (2000) TheS,X-acetals in nucleoside chemistry: II. The synthesis of 3′-O-methylthiomethylribonucleosides. Russian Journal of Bioorganic Chemistry 26:6, pages 407-413.
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A. E. Pechenov, S. G. Zavgorodny, V. I. Shvets & A. I. Miroshnikov. (2000) TheS,X-acetals in nucleoside chemistry. I. The synthesis of 2′- and 5′-O-methylthiomethylribonucleosides. Russian Journal of Bioorganic Chemistry 26:5, pages 327-333.
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Martin Dunkel & Vivian Reither. (1999) Synthesis of 2′-C-α-difluoromethylarauridine and its 3′-O-phosphoramidite incorporation into a hammerhead ribozyme. Bioorganic & Medicinal Chemistry Letters 9:5, pages 787-792.
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