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Nucleosides and Nucleotides Volume 16, 1997 - Issue 7-9
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VIII. SPECIAL TOPICS

Histological Localization of Phosphorothioate Oligodeoxynucleotides in Normal Rodent Tissue

Madeline Butler Isis Pharmaceuticals, Carlsbad, CA, 92008
,
Kim Stecker Isis Pharmaceuticals, Carlsbad, CA, 92008
&
C. Frank Bennett Isis Pharmaceuticals, Carlsbad, CA, 92008
Pages 1761-1764 | Published online: 16 Aug 2006

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Scott P Henry & Ronald P Danis. (2001) Potential therapeutic application of antisense oligonucleotides in the treatment of ocular diseases. Expert Opinion on Pharmacotherapy 2:2, pages 277-291.
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Articles from other publishers (10)

Tae-Won KimChris PapagiannisDaniel CapaldiAndrew K. McPhersonFarah MahdiNhuy LuuAndrew A. RodriguezChristine HoffmasterDavid SerotaScott P. Henry. (2020) Impurity Qualification Toxicology Study for a 2′-O-Methoxyethyl-Modified Antisense Inhibitor in Mice. Nucleic Acid Therapeutics 30:1, pages 14-21.
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Jeffery A. Engelhardt. (2016) Comparative Renal Toxicopathology of Antisense Oligonucleotides. Nucleic Acid Therapeutics 26:4, pages 199-209.
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Scott P. Henry, Mark Johnson, Thomas A. Zanardi, Robert Fey, Diana Auyeung, Patrick B. Lappin & Arthur A. Levin. (2012) Renal uptake and tolerability of a 2′-O-methoxyethyl modified antisense oligonucleotide (ISIS 113715) in monkey. Toxicology 301:1-3, pages 13-20.
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Shayne Cox GadArthur A. Levin & Scott P. Henry. 2010. Pharmaceutical Sciences Encyclopedia. Pharmaceutical Sciences Encyclopedia.
Richard S. Geary, Ed Wancewicz, John Matson, Megan Pearce, Andrew Siwkowski, Eric Swayze & Frank Bennett. (2009) Effect of dose and plasma concentration on liver uptake and pharmacologic activity of a 2′-methoxyethyl modified chimeric antisense oligonucleotide targeting PTEN. Biochemical Pharmacology 78:3, pages 284-291.
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Nancy Goebl, Brian Berridge, Victor J. Wroblewski & Patricia L. Brown-Augsburger. (2016) Development of a Sensitive and Specific in Situ Hybridization Technique for the Cellular Localization of Antisense Oligodeoxynucleotide Drugs in Tissue Sections. Toxicologic Pathology 35:4, pages 541-548.
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Lilit MasarjianAnn De PeysterArthur A. LevinDavid K. Monteith. (2004) Distribution and Excretion of a Phosphorothioate Oligonucleotide in Rats with Experimentally Induced Renal Injury. Oligonucleotides 14:4, pages 299-310.
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Arthur A Levin. (1999) A review of issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides. Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression 1489:1, pages 69-84.
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Richard S. Geary, John Matson & Arthur A. Levin. (1999) A Nonradioisotope Biomedical Assay for Intact Oligonucleotide and Its Chain-Shortened Metabolites Used for Determination of Exposure and Elimination Half-Life of Antisense Drugs in Tissue. Analytical Biochemistry 274:2, pages 241-248.
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Scott P. HenryMichael V. Templin, Nancy Gillett, Jennifer Rojko & Arthur A. Levin. (2016) Correlation of Toxicity and Pharmacokinetic Properties of a Phosphorothioate Oligonucleotide Designed to Inhibit ICAM-1. Toxicologic Pathology 27:1, pages 95-100.
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