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ORIGINAL ARTICLES Clinical Translational Therapeutics

Expression Profile of Human Beta-Defensin 3 in Oral Squamous Cell Carcinoma

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Pages 575-581 | Published online: 20 Jul 2009

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Kim A Brogden, Georgia K Johnson, Steven D Vincent, Taher Abbasi & Shireen Vali. (2013) Oral inflammation, a role for antimicrobial peptide modulation of cytokine and chemokine responses. Expert Review of Anti-infective Therapy 11:10, pages 1097-1113.
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J. Winter, S. Mohr, A. Pantelis, D. Kraus, J.P. Allam, N. Novak, R. Reich, M. Martini, S. Jepsen, W. Götz & M. Wenghoefer. (2012) IGF-1 Deficiency in Combination with a Low Basic hBD-2 and hBD-3 Gene Expression Might Counteract Malignant Transformation in Pleomorphic Adenomas in Vitro. Cancer Investigation 30:2, pages 106-113.
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Jochen Winter, Annette Pantelis, Rudolf Reich, Soeren Jepsen, Jean Piere Allam, Natalija Novak & Matthias Wenghoefer. (2011) Risk Estimation for a Malignant Transformation of Oral Lesions by S100A7 and Doc-1 Gene Expression. Cancer Investigation 29:7, pages 478-484.
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Jochen Winter, Annette Pantelis, Rudolf Reich, Markus Martini, Dominik Kraus, Soeren Jepsen, Jean-Pierre Allam, Natalija Novak & Matthias Wenghoefer. (2011) Human Beta-Defensin-1, -2, and -3 Exhibit Opposite Effects on Oral Squamous Cell Carcinoma Cell Proliferation. Cancer Investigation 29:3, pages 196-201.
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Articles from other publishers (40)

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Mutlu Keskin, Emma Suomi, İlknur Harmankaya, Didem Karaçetin, Timo Sorsa & Ulvi Kahraman Gürsoy. (2023) Oral Cavity Beta-Defensin Levels Are Regulated Differently during Radiotherapy in Head and Neck Cancer Patients. Applied Sciences 13:4, pages 2056.
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Yongxiu Du, Yanlan Yang, Wenbo Zhang, Chenxi Yang & Pu Xu. (2023) Human β-defensin-3 and nuclear factor-kappa B p65 synergistically promote the cell proliferation and invasion of oral squamous cell carcinoma. Translational Oncology 27, pages 101582.
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Chongyi Zhao, Shuo Yan, Yuzhu Song & Xueshan Xia. (2022) Roles of Antimicrobial Peptides in Gynecological Cancers. International Journal of Molecular Sciences 23:17, pages 10104.
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John Yun Niu, Iris Xiaoxue Yin, May Lei Mei, William Ka Kei Wu, Quan‐Li Li & Chun Hung Chu. (2021) The multifaceted roles of antimicrobial peptides in oral diseases. Molecular Oral Microbiology 36:3, pages 159-171.
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Noura Al Mansour, Ghada Al-Kafaji, Ali Al Mahmeed & Khalid M Bindayna. (2021) Dysregulation of human beta-defensin-3 expression in the peripheral blood of patients with sepsis. SAGE Open Medicine 9, pages 205031212110415.
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Dan Xu & Wuyuan Lu. (2020) Defensins: A Double-Edged Sword in Host Immunity. Frontiers in Immunology 11.
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Maria Paula Gomez Hernandez, Amber M. Bates, Emily E. Starman, Emily A. Lanzel, Carissa Comnick, Xian Jin Xie & Kim A. Brogden. (2019) HBD3 Induces PD-L1 Expression on Head and Neck Squamous Cell Carcinoma Cell Lines. Antibiotics 8:4, pages 161.
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Santosh K. Ghosh, Thomas S. McCormick & Aaron Weinberg. (2019) Human Beta Defensins and Cancer: Contradictions and Common Ground. Frontiers in Oncology 9.
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Ge Jin & Aaron Weinberg. (2019) Human antimicrobial peptides and cancer. Seminars in Cell & Developmental Biology 88, pages 156-162.
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Anne M. van der Does, Pieter S. Hiemstra & Neeloffer Mookherjee. 2019. Antimicrobial Peptides. Antimicrobial Peptides 149 171 .
De Yang, Zhen Han & Joost J. Oppenheim. (2017) Alarmins and immunity. Immunological Reviews 280:1, pages 41-56.
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Nityasri Venkiteswaran, Kassapa Ellepola, Chaminda Seneviratne, Yuan Lee, Kia Puan & Siew Wong. 2017. Microbial Biofilms. Microbial Biofilms 203 236 .
Dan Xu, Bing Zhang, Chongbing Liao, Wei Zhang, Weijia Wang, Ying Chang & Yongping Shao. (2016) Human beta-defensin 3 contributes to the carcinogenesis of cervical cancer via activation of NF-κB signaling. Oncotarget 7:46, pages 75902-75913.
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T. Hoppe, D. Kraus, N. Novak, R. Probstmeier, M. Frentzen, M. Wenghoefer, S. Jepsen & J. Winter. (2016) Oral pathogens change proliferation properties of oral tumor cells by affecting gene expression of human defensins. Tumor Biology 37:10, pages 13789-13798.
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Jochen Winter, Dominik Kraus, Jan Reckenbeil & Rainer Probstmeier. (2015) Oncogenic relevant defensins: expression pattern and proliferation characteristics of human tumor cell lines. Tumor Biology 37:6, pages 7959-7966.
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W Nittayananta. (2016) Oral fungi in HIV: challenges in antifungal therapies. Oral Diseases 22, pages 107-113.
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Nattawut Leelakanok, Carol L. Fischer, Amber M. Bates, Janet M. Guthmiller, Georgia K. Johnson, Aliasger K. Salem, Kim A. Brogden & Nicole K. Brogden. (2015) Cytotoxicity of HBD3 for dendritic cells, normal human epidermal keratinocytes, hTERT keratinocytes, and primary oral gingival epithelial keratinocytes in cell culture conditions. Toxicology Letters 239:2, pages 90-96.
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Meggy Suarez-Carmona, Pascale Hubert, Philippe Delvenne & Michael Herfs. (2015) Defensins: “Simple” antimicrobial peptides or broad-spectrum molecules?. Cytokine & Growth Factor Reviews 26:3, pages 361-370.
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Aornrutai Promsong, Whasun Oh Chung, Surada Satthakarn & Wipawee Nittayananta. (2015) Ellagic acid modulates the expression of oral innate immune mediators: potential role in mucosal protection. Journal of Oral Pathology & Medicine 44:3, pages 214-221.
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Izzat A. M. Al-Rayahi & Raghad H. H. Sanyi. (2015) The Overlapping Roles of Antimicrobial Peptides and Complement in Recruitment and Activation of Tumor-Associated Inflammatory Cells. Frontiers in Immunology 6.
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Whasun Lim & Gwonhwa Song. (2013) Discovery of Prognostic Factors for Diagnosis and Treatment of Epithelial-Derived Ovarian Cancer from Laying Hens. Journal of Cancer Prevention 18:3, pages 209-220.
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Piyushi Gupta, Sadashib Ghosh, Ashwat Nagarajan, Veer Singh Mehta & Ellora Sen. (2013) β-defensin-3 negatively regulates TLR4–HMGB1 axis mediated HLA-G expression in IL-1β treated glioma cells. Cellular Signalling 25:3, pages 682-689.
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Lauren E. Harvey, Karl G. Kohlgraf, Leslie A. Mehalick, Monica Raina, Erica N. Recker, Saumya Radhakrishnan, Samiksha Avinash Prasad, Robinson Vidva, Ann Progulske-Fox, Joseph E. Cavanaugh, Shireen Vali & Kim A. Brogden. (2013) Defensin DEFB103 bidirectionally regulates chemokine and cytokine responses to a pro-inflammatory stimulus. Scientific Reports 3:1.
Crossref
Wipawee Nittayananta, Marisa Kemapunmanus, Korntip Amornthatree, Sineepat Talungchit & Hutcha Sriplung. (2012) Oral human β‐defensin 2 in HIV‐infected subjects with long‐term use of antiretroviral therapy. Journal of Oral Pathology & Medicine 42:1, pages 53-60.
Crossref
Jochen Winter, Annette Pantelis, Dominik Kraus, Jan Reckenbeil, Rudolf Reich, Soeren Jepsen, Hans-Peter Fischer, Jean-Pierre Allam, Natalija Novak & Matthias Wenghoefer. (2012) Human α-defensin (DEFA) gene expression helps to characterise benign and malignant salivary gland tumours. BMC Cancer 12:1.
Crossref
Niharika Swain, Shwetha V. Kumar, Richa & Jigna Pathak. (2012) DEFENSINS: Potent biomarkers in Oral Squamous cell Carcinoma. Oral Oncology 48:8, pages e29-e30.
Crossref
Johann Röhrl, Barbara Huber, Gudrun E. Koehl, Edward K. Geissler & Thomas Hehlgans. (2012) Mouse β-Defensin 14 ( Defb14 ) Promotes Tumor Growth by Inducing Angiogenesis in a CCR6-Dependent Manner . The Journal of Immunology 188:10, pages 4931-4939.
Crossref
D. Kraus, J. Deschner, A. Jäger, M. Wenghoefer, S. Bayer, S. Jepsen, J. P. Allam, N. Novak, R. Meyer & J. Winter. (2011) Human β‐defensins differently affect proliferation, differentiation, and mineralization of osteoblast‐like MG63 cells. Journal of Cellular Physiology 227:3, pages 994-1003.
Crossref
Jochen Winter & Matthias Wenghoefer. (2012) Human Defensins: Potential Tools for Clinical Applications. Polymers 4:1, pages 691-709.
Crossref
Marco R. Kesting, Mechthild Stoeckelhuber, Alexandra Kuppek, Rafael Hasler, Nils Rohleder, Klaus-Dietrich Wolff & Markus Nieberler. (2012) Human β-Defensins and Psoriasin/S100A7 Expression in Salivary Glands. BioDrugs 26:1, pages 33-42.
Crossref
Fiona Semple & Julia R. Dorin. (2012) ß-Defensins: Multifunctional Modulators of Infection, Inflammation and More?. Journal of Innate Immunity 4:4, pages 337-348.
Crossref
Yu Shuyi, Wang Feng, Tang Jing, Huang Hongzhang, Wang Haiyan, Ma Pingping, Zheng Liwu, Roger A. Zwahlen & Yang Hongyu. (2011) Human beta-defensin-3 (hBD-3) upregulated by LPS via epidermal growth factor receptor (EGFR) signaling pathways to enhance lymphatic invasion of oral squamous cell carcinoma. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology 112:5, pages 616-625.
Crossref
G Diamond & LK Ryan. (2011) Beta-defensins: what are they REALLY doing in the oral cavity?. Oral Diseases 17:7, pages 628-635.
Crossref
Denys J. Loeffelbein, Lars Steinstraesser, Nils H. Rohleder, Rafael J. Hasler, Frank Jacobsen, Matthias Schulte, Jana Schnorrenberg, Frank Hölzle, Klaus-Dietrich Wolff & Marco R. Kesting. (2011) Expression of host defence peptides in the lip vermilion mucosa during early infancy. Journal of Oral Pathology & Medicine 40:8, pages 598-603.
Crossref
Whasun O. Chung & Henrik Dommisch. 2011. Innate Immune System of Skin and Oral Mucosa. Innate Immune System of Skin and Oral Mucosa 117 144 .
Y. K. Mburu, K. Abe, L. K. Ferris, S. N. Sarkar & R. L. Ferris. (2010) Human  -defensin 3 promotes NF- B-mediated CCR7 expression and anti-apoptotic signals in squamous cell carcinoma of the head and neck. Carcinogenesis 32:2, pages 168-174.
Crossref
Linda Hazlett & Minhao Wu. (2010) Defensins in innate immunity. Cell and Tissue Research 343:1, pages 175-188.
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Ge Jin. (2010) Using biomarkers to detect oral cancer holds potential for saving lives when the cancer is most curable. Biomarkers in Medicine 4:6, pages 835-838.
Crossref
Ge Jin, Hameem I. Kawsar, Stanley A. Hirsch, Chun Zeng, Xun Jia, Zhimin Feng, Santosh K. Ghosh, Qing Yin Zheng, Aimin Zhou, Thomas M. McIntyre & Aaron Weinberg. (2010) An Antimicrobial Peptide Regulates Tumor-Associated Macrophage Trafficking via the Chemokine Receptor CCR2, a Model for Tumorigenesis. PLoS ONE 5:6, pages e10993.
Crossref

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